Hydrolysis kinetics of propylene glycol monomethyl ether acetate in rats in vivo and in rat and human tissues in vitro

Toxicological Sciences

Volumn 75, Issue 1, 2003, Pages 31-39

  Domoradzki, J Y ^a   Brzak, K A ^a   Thornton, C M ^a  

^a DOW CHEMICAL COMPANY   (United States)

Author keywords

Human metabolism; Pharmacokinetics; Propylene glycol monomethyl ether; Propylene glycol monomethyl ether acetate; Rat metabolism

Indexed keywords

ACETIC ACID DERIVATIVE; DIMETHYL ETHER; PROPYLENE GLYCOL; SOLVENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; CALCULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DATA BASE; HUMAN; HUMAN TISSUE; HYDROLYSIS KINETICS; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LIVER; LIVER HOMOGENATE; MALE; NONHUMAN; PLASMA HALF LIFE; RAT; RAT STRAIN; TOXICOLOGY;

ANIMALS; AREA UNDER CURVE; HALF-LIFE; HUMANS; HYDROLYSIS; INJECTIONS, INTRAVENOUS; LIVER; MALE; PROPYLENE GLYCOLS; RATS; RATS, INBRED F344; SPECIES SPECIFICITY; TIME FACTORS;

ANIMALIA;

EID: 0042883950     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg177     Document Type: Article

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