Agrobacterium biology and crown gall disease

Plant-Associated Bacteria

Volumn , Issue , 2006, Pages 359-384

  Anand, Ajith ^a   Mysore, Kirankumar S ^a  

^a PLANT BIOLOGY DIVISION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84892037095     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4020-4538-7_11     Document Type: Chapter

References (169)

1. Akiyoshi, D. E., Klee, H., Amasino, R. M., Nester, E. W., & Gordon, M. P. (1984). T-DNA of Agrobacterium tumefaciens encodes an enzyme of cytokinin biosynthesis Proc. Natl. Acad. Sci., USA, 81, 5994-5998.
2. Allardet-Servant, A., Michaux-Charachon, S., Jumas-Bilak, E., Karayan, L., & Ramuz, M. (1993). Presence of one linear and one circular chromosome in the Agrobacterium tumefaciens C58 genome. J. Bacteriol., 175, 7869-7874.
3. Anand, A., & Mysore, K. S. (2005). Current advances in Agrobacterium-plant interactions and their implications on agricultural biotechnology. In A. Hemantarajan (Ed.), Advances in Plant Physiol: An International Treatise Series, Jodhpur: Scientific publishers (in press).
4. Ashby, A. M., Watson, M. D., Ladke, G. J., & Shaw, C. H. (1988). Ti plasmid-specified chemotaxis of Agrobacterium tumefaciens C58C1 toward vir-inducing phenolic compounds and soluble factores from monocotyledonous and dicotyledonous plants. J. Bacteriol., 170, 4181-4187.
5. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J. W., et al. (1996). SKP1 connects cell cycle regutlators to the ubiquitin proteolysis machinery through a novel motiff, F- box. Cell, 86, 263-274.
6. Bako, L., Umeda, M., Tiburcio, A. F., Schell, J., & Koncz, C. (2003). The VirD2 pilot protein of Agrobacterium-transferred DNA interacts with the TATA box-binding protein and a nuclear protein kinase in plants. Pro Natl. Acad. Sci., USA, 100, 10108-10113.
7. Ballas, N., & Citovsky, V. (1997). Nuclear localization signal binding protein from Arabidopsis mediates nuclear import of Agrobacterium VirD2 protein. Proc. Natl. Acad. Sci., USA, 94, 10723- 10728.
8. Baron, C., Llosa, M., Zhou, s., & Zambryski, P. C. (1997). VirB1, a component of the T-complex transfer machinery of Agrobacterium tumefaciens is processed to a C-terminal secreted product VirB1. J Bacteriol., 179, 1203-1210.
9. Barry, G. F., Rogers, S. G., Fraley, R. T., & Brand, L. (1984). Identification of a cloned cytokinin biosynthetic gene. Proc. Natl. Acad. Sci., USA, 81, 4776-4780.
10. Bash, R., & Matthysse, A. G. (2002). Attachment to roots and virulence of a chvB mutant of Agrobacterium tumefaciens are temperature sensitive. Mol. Plant Microbe Interact., 15, 160-163.
11. Baulcombe, D. C. (1999). Fast forward genetics based on virus-induced gene silencing. Curr. Opin. Plant Biol., 2, 109-113.
12. Binns, A. N., Beaupre, C. E., & Dale, M. (1995). Inhibition of VirB-mediated transfer of diversessubstrate from Agrobacterium tumefaciens by the IncQ plasmid RSF100. J. Bacteriol., 177, 4890-4899.
13. Braun, A. (1954). The physiology of plant tumors. Ann. Rev. Plant Physiol., 5, 133-162.
14. Braun, A. C. (1978). Plant tumors. Biochim. Biophys. Acata., 516, 167-191.
15. Braun, A. C. (1982). A history of the crown gall problem. In G. Kahl & J. Schell (Eds.), Molecular biology of plant tumors (pp. 155-210). New York: Academic Press.
16. Broothaerts, W., Mitchell, H. J., Weir, B., Kaines, S., Smith, L. M. A., Yang, W., et al. (2005). Gene transfer to plants by diverse species of bacteria. Nature, 433, 629-633.
17. Buchmann, I., Marner, F.-J., Schroder, G., Waffenschmidt, S., & Schroder, J. (1985). Tumour genes in plants: T-DNA encoded cytokinin biosynthesis EMBO J., 4, 853.
18. Bundock, P., & Hooykaas, P. J. (2002). Severe developmental defects, hypersensitivity to DNAdamaging agents, and lengthened telomeres in Arabidopsis MRE11 mutants. Plant Cell, 14, 2451- 2462.
19. Bundock, P., van Attikum, H., & Hooykaas, P. J. (2002). Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis 70 mutant. Nucl. Acids Res., 30, 3395-3400.
20. Burr, T. J., Bazzi, C., Sule, S., & Otten, L. (1998). Biology of Agrobactereium vitis and the development of disease control strategies. Plant Dis., 82, 1288-1297.
21. Burr, T. J., & Otten, L. (1999). Crown gall of grape: biology disease management. Annu. Rev. Phytopathol., 37, 53-80.
22. Cangelosi, G. A., Ankenbauer, R. G., & Nester, E. W. (1990). Sugars induce the Agrobacterium virulence genes through a periplasmic binding protein and a transmembrande signal protein. Proc. Natl. Acad. Sci., USA, 87, 6708-6712.
23. Cangelosi, G. A., Hung, L., Puvanesarajah, V., Stacey, G., Ozga, D. A., Leigh, J. A., et al. (1987). Common loci for Agrobacterium tumefaciens and Rhizobium meliloti exopolysaccharide synthesis and their roles in plant interactions J. Bacteriol., 169, 2086-2091.
24. Cascales, E., & Christie, P. J. (2004). Definition of a Bacterial Type IV Secretion Pathway for a DNA Substrate. Science, 304, 1170-1173.
25. Chen, L., Li, C. M., & Nester, E. W. (2000). Transferred DNA (T-DNA)-associated proteins of Agrobacterium tumefaciens are exported independently of virB. Pro. Natl. Acad. Sci., USA, 97, 7545-7550.
26. Chilton, M.-D., Drummond, M. H., Merlo, D. J., Sciaky, D., Montoya, A. L., Gordon, M. P., et al. (1977). Stable incorporation of plasmid DNA into higher plant cells: The molecular basis of crown gall tumorigenesis. Cell, 11, 263-271.
27. Chilton, M.-D., & Que, Q. (2003). Targeted integration of T-DNA into the tobacco genome at doublestranded breaks: new insights on the mechanism of T-DNA integration. Plant Physiol., 133, 956- 965.
28. Christie, P. J. (1997). Agrobacterium tumefaciens T-complex transport apparatus: A paradigm for a new family of multifunctional transporters in Eubacteria. J. Bacteriol., 179, 3085-3094.
29. Christie, P. J. (2001). Type IV secretion: Intercellular transfer of macromolecules by systems ancestrally related to conjugation machines. Mol. Microbiol., 40, 294-305.
30. Christie, P. J. (2004). Type IV secretion: The Agrobacterium VirB/D4 and related conjugation systems. Biochem. Biophys. Acta., 1694, 219-234.
31. Christie, P. J., & Vogel, J. P. (2000). Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells. Trends Microbiol., 8, 354-360.
32. Christie, P. J., Ward, J. E., Winans, S. C., & Nester, E. W. (1988). The Agrobacterium tumefaciens VirE2 gene product is a single -stranded-DNA-binding protein that associates with T-DNa. J. Bacteriol., 170, 2659-2667.
33. Citovsky, V., De Vos, G., & Zambryski, P. C. (1988). Single-stranded DNA binding protein encoded by the virE locus of Agrobacterium tumefaciens. Science, 240, 501-504.
34. Citovsky, V., Guralnick, B., Simon, M. N., & Wall, J. S. (1997). The molecular structure of Agrobacterium VirE2-single stranded DNA complexes involved in nuclear import. J. Mol. Biol., 271, 718-727.
35. Citovsky, V., Warnick, D., & Zambryski, P. C. (1994). Nuclear import of Agrobacterium VirD2 and VirE2 proteins in maize and tobacco. Proc. Natl. Acad. Sci., USA, 91, 3210-3214.
36. Citovsky, V., Wong, M. L., & Zambryski, P. C. (1989). Coooperative interaction of Agrobacterium VirE2 protein with single-stranded DNA: Implications for the T-DNA transfer process. Pro. Natl. Acad. Sci., USA, 86, 1193-1197.
37. Citovsky, V., Zupan, J., Warnick, D., & Zambryski, P. C. (1992). Nuclear localization of Agrobacterium VirE2 protein in plant cells. Science, 256, 1802-1805.
38. Collart, M. A. (2003). Global control of gene expression in yeast by the Ccr4-Not complex. Gene, 313, 1-16.
39. Collart, M. A., & Struhl, K. (1993). CDC39 an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible his3 promoters. EMBO J., 12, 177-186.
40. Das, A., Stachel, S., Ebert, P., Allenza, P., Montoya, A. L., & Nester, E. W. (1986). Promoters of Agrobacterium tumefaciens Ti-plasmid virulence genes. Nucl. Acids Res., 14, 1355-1364.
41. Davey, M. R., Curtis, I. S., Gartland, K. M. A., & Power, J. B. (1994). Agrobacterium-induced crown gall and hairy root diseases: Their biology and application to plant genetic engineering. In M. A. J. Williams (Ed.), Plant Galls (Vol. 49, pp 9-55). Systematics Association.
42. de Groot, M. J., Bundock, P., Hooykaas, P. J., & Beijersbergen, A. G. (1998). Agrobacterium tumefaciens-mediated transformation of filamentous fungi. Nat. Biotechnol., 16, 839-842.
43. de Iannino, N. I., & Ugalde, R. A. (1989). Biochemical characterization of avirulent Agrobacterium tumefaciens chvA mutants: Synthesis and excretion of beta-(1-2) gulcan. J. Bacteriol., 171, 2842- 2849.
44. Deng, W., Chen, L., Wood, D. W., Metcalfe, T., Liang, X., Gordon, M. P., et al. (1998). Agrobacterium VirD2 protein interacts with plant host cyclophilins. Proc. Natl. Acad. Sci., USA, 95, 7040-7045.
45. Dessaux, Y., Petit, A., Farrand, S. K., & Murphy, P. J. (1998). Opines and opine-like molecules involved in plant-Rhizobiaceae interactions. In H. P. Spaink, A. Kondorosi & P. J. J. Hooykass (Eds.), The Rhizobiaceae: molecular biology of model plant-asscociated bacteria. Dordrecht: Kluwer Academic Publishers.
46. Dinesh-Kumar, P., Anandalakshmi, R., Marathe, R., Schiff, M., & Liu, Y. (2003). Virus-induced gene silencing in Methods. In E. Grotewold (Ed.), Molecular Biology, Plant Functional Genomics: Methods and Protocols (Vol. 236, pp. 287-293). Totowa: Humana Press.
47. Ditt, R. F., Nester, E. W., & Comai, L. (2001). Plant gene expression response to Agrobacterium tumefaciens. Proc. Natl. Acad. Sci., USA, 98, 10954-10959.
48. Doty, S. L., Yu, M. C., Lundin, J. I., Heath, J. D., & Nester, E. W. (1996). Mutational analysis of the input domain of the VirA protein of Agrobacterium tumefaciens. J. Bacteriol., 178, 961-970.
49. Douglas, C., Halperin, W., Gordon, M. P., & Nester, E. W. (1985a). Specific attachment of Agrobacterium tumefaciens to bamboo cells in suspension cultures. J. Bacteriol., 161, 764-766.
50. Douglas, C. J., Staneloni, R. J., Rubin, R. A., & Nester, E. W. (1985b). Identification and genetic analysis of an Agrobacterium tumefaciens chromosomal virulence region. J. Bacteriol., 161, 850- 860.
51. Dworetzky, S. I., & Feldher, C. M. (1988). Translocation of RNA-coated gold particles through the nuclear pores of oocytes. J. Cell. Biol., 106, 575-584.
52. Escobar, M. A., Civerolo, E. L., Kristin, R., Summerfelt, K. R., & Dandekar, A. M. (2001). RNAimediated oncogene silencing confers resistance to crown gall tumorigenesis. Proc. Natl. Acad. Sci., USA, 98, 13437-13442.
53. Escobar, M. A., & Dandekar, A. M. (2003). Agrobacterium tumefaciens as an agent of disease. Trends Plant Sci, 8, 380-386.
54. Escudero, J., & Hohn, B. (1999). Transfer and integration of T-DNA without cell injury in the host plant. Plant Cell, 9, 2135-2142.
55. Farrand, S. K., van Berkum, P. B., & Oger, P. (2003). Agrobacterium is a definable genus of the family Rhizobiaceae. Int. J. Syst. Evol. Microbiol., 53, 1681-1687.
56. Firth, N., Ippen-Ihler, K., & Skurray, R. A. (1996). Structure and function of the F factor and mechanism of conjugation. In F. C. Neidhardt, R. C. III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznifoff, M. Riley, M. Schaechter & H. C. Umbarger (Eds.), Escherichia coli and Salmonella: cellular and molecular biology 2nd Edition. Washington D.C.: American Society for Microbiology.
57. Frolov, M. V., Benevolenskaya, E. V., & Birchler, J. A. (1998). Regena (Rga), a Drosophila Homolog of the Global Negative Transcriptional Regulator CDC36 (NOT2) from Yeast, Modifies Gene Expression and Suppresses Position Effect Variegation. Genetics, 148, 317-330.
58. Gallego, M. E., Jalut, N., & White, C. I. (2003). Telomerase dependence of telomere lengthening ku80 mutant Arabidopsis. Plant Cell, 15, 782-789.
59. Garfinkel, D. J., Simpson, R. B., Ream, L. W., White, F. F., Gordon, M. P., & Nester, E. W. (1981). Genetic analysis of crown gall: Fine structure map of the T-DNA by sit-directed mutagenesis. Cell, 27, 143-153.
60. Gelvin, S. B. (1998). Agrobacterium VirE2 proteins can form a complex with T strands in the plant cytoplasm. J. Bacteriol., 180, 4300-4302.
61. Gelvin, S. B. (2000). Agrobacterium and plant genes involved in T-DNA transfer and integration. Annu. Rev. Plant Physiol. Plant Mol. Biol., 51, 223-256.
62. Gelvin, S. B. (2003). Agrobacterium-mediated plant transformation: The biology behind the "genejockeying" tool. Microbiol. Mol. Biol. Rev., 67, 16-37.
63. Goodner, B., Hinkle, G., Gattung, S., Miller, N., Blanchard, M., Qurollo, B., et al. (2001). Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58. Science, 294, 2323-2328.
64. Hooykaas, P. J., Hofker, M., den Dulk-Ras, A., & Schilperoort, R. A. (1984). A comparison of virulence determinants in an octopine Ti plasmid, a nopaline Ti plasmid and an Ri plasmid by complementation analysis of Agrobacterium tumefaciens mutants. Plasmid, 11, 195-205.
65. Hooykaas, P. J., & Shilperoort, R. A. (1992). Agrobacterium and plant genetic engineering. Plant Mol. Biol., 19, 15-38.
66. Howard, E., Zupan, J., Citovsky, V., & Zambryski, P. C. (1992). The VirD2 protein of A. tumefaciens contains a C-terminal bipartite nuclear localization signal: Implications for nuclear uptake of DNA in plant cells. Cell, 68, 109-118.
67. Hwang, H.-H., & Gelvin, S. B. (2004). Plant Proteins That Interact with VirB2, the Agrobacterium tumefaciens Pilin Protein, Mediate Plant Transformation. Plant Cell, 16, 3148-3167.
68. Iyer, V. N., Klee, H. J., & Nester, E. W. (1982). Units of genetic expression in the virulence region of a plant tumor-inducing plasmid of Agrobacterium tumefaciens. Mol. Gen. Genet., 188, 418-424.
69. Jin, S., Prusti, R. K., Roitsch, T., Ankenbauer, R. G., & Nester, E. W. (1990). Phosphorylation of the VirG protein of Agrobacterium tumefaciens by the autophosphorylated VirA protein: Essential role in biological activity of VirG J. Bacteriol., 172, 4945.
70. Jin, S., Roitsch, T., Christie, P. J., & Nester, E. W. (1990). The regulatoy VirG protein specifically binds to a cis-acting regulatory sequence involved in transcriptional activation of Agrobacterium tumefaciens virulence genes J. Bacteriol., 172, 531.
71. Jin, S., Song, Y., Pan, S., & Nester, E. W. (1993). Characterization of a virG mutation that confers constitutive virulence gene expression in Agrobacterium tumefaciens. Mol. Microbiol., 7, 555-562.
72. Kado, C. I. (2000). The role of T-pilus in horizontal gene transfer and tumorigenesis. Curr. Opin. Microbiol., 3, 643-648.
73. Keane, P. J., Kerr, A., & New, P. B. (1970). Crown gall of stone fruit. II. indentification and nomenclature of Agrobacterium isolates. Aust. J. Biol. Sci., 23, 585-595.
74. Kerr, A., & Panagopoulos, C. G. (1977). Biotypes of IAgrobacterium radiobacter var. tubefaciens and their biiological control. Phytopathol Z., 90, 172-179.
75. Kim, C.-H., Baek, J. K., Lee, J., Yang, M., & Farrand, S. K. (2001). Intracellular accumulation of mannopine, an opine produced by crown gall tumors, transiently inhibits growth of Agrobacterium tumefaciens. Mol. Plant Microbe Interact., 14, 793-803.
76. Koepp, D. M., Harper, J. W., & Elledge, S. J. (1999). How the cyclin became a cyclin: regulated proteolysis in the cell cycle. Cell, 97, 431-434.
77. Kovalchuk, O., Telyuk, P., Kovalchuk, L., Kovalchuk, I., & Titov, V. (2003). Novel plant bioassays for monitoring the genotoxicity of drinking water from the inhabited areas of the Ukraine affected by the Chernobyl accident. Bull. Environ. Contam. Toxicol., 70, 847-853.
78. Kunik, T., Tzfira, T., Kapulnik, Y., Gafni, Y., Dingwall, C., & Citovsky, V. (2001). Genetic transformation of HeLa cells by Agrobacterium. Proc. Natl. Acad. Sci., USA, 98, 1871-1876.
79. Lacroix, B., Vaidya, M., Tzfira, T., & Citovsky, V. (2005). The VirE3 protein of Agrobacterium mimics a host cell function required for plant genetic transformation. EMBO J., 24, 428-437.
80. Lee, H., Humann, J. L., Pitrak, J. S., Cuperus, J. T., Parks, T. D., Whistler, C. A., et al. (2003). Translation start sequences affect the efficiency of silencing of Agrobacterium tumefaciens T-DNA oncogenes. Plant Physiol., 133, 966-977.
81. Lee, Y.-W., Jin, S., Sim, W.-S., & Nester, E. W. (1995). Genetic evidence for direct sensing of phenolic compounds by the VirA protein of Agrobacterium tumefaciens. Proc. Natl. Acad. Sci., USA, 92, 12245-12249.
82. Lessl, M., & Lanka, E. (1994). Common mechanisms in bacterial conjugation and Ti-mediated T-DNA transfer to plant cells. Cell, 77, 321-324.
83. Li, J., Krichevsky, A., Vaidya, M., Tzfira, T., & Citovsky, V. (2005). Uncoupling of the functions of the Arabidopsis VIP1 protein in transient and stable plant genetic transformation by Agrobacterium. Proc. Natl. Acad. Sci., USA, 102, 5733-5738.
84. Li, J., Wolf, S. G., Elbaum, M., & Tzfira, T. (2005). Exploring cargo transport mechanics in the type IV secretion systems. Trends in Microbiol., 13, 295-298.
85. Lippincott, B. B., & Lippincot, J. A. (1969). Bacterial attachment to a specific wound site as an essential stage in tumor initiation by Agrobacterium tumefaciens. J. Bacteriol., 97, 620-628.
86. Lippincott, J. A., & Lippincott, B. B. (1981). Crown gall, a "alignant plant tumor". In H. E. Kaiser (Ed.), Neoplasms: Comparative pathology of growth in animals, plants, and man. Baltimore: Williams & Wilkins.
87. Liu, Y., Schiff, M., & Dinesh-Kumar, P. (2002). Virus-induced gene silencing in tomato. Plant J., 31, 777-786.
88. Liu, Y., Schiff, M., Marathe, R., & Dinesh-Kumar, P. (2002). Tobacco Rar1, EDS1 and NPR1/NIMI1 like genes are required for N-mediated resistance to tobacco mosaic virus. Plant J., 30, 415-429.
89. Matthysse, A. G. (1986). Initial interactions of Agrobacterium tumefaciens with plant host cells. Cri. Rev. Microbiol., 13, 281-307.
90. Matthysse, A. G. (1994). Conditoned medium promotes the attachment of Agrobacterium tumefaciens strain NT1 to carrot cells. Protoplasma, 183, 131-136.
91. Matthysse, A. G., Yarnall, H. A., & Young, N. (1996). Requirement for genes with homology to ABC transport systems for attachment and virulence of Agrobacterium tumefaciens. J. Bacteriol., 178, 5302-5308.
92. Mittendorf, V. V., Robertson, E. J., Leech, R. M., Kruger, N., Steinbuchel, A., & Poirier, Y. (1998). Synthesis of medium-chain-length polyhydroxyalkanoates in Arabidosis thaliana using intermediates of peroxisomal fatty acid betaoxidation. Proc. Natl. Acad. Sci., USA, 95, 13397- 13402.
93. Mysore, K. S., Ranjith Kumar, C. T., & Gelvin, S. B. (2000). Arabidipsis ecotypes and mutants that are recalcitrant to Agrobacterium rooot transformation are susceptible to germ-line transformation. Plant J., 21, 9-16.
94. Nair, G. R., Liu, Z., & Binns, A. N. (2003). Re-examining the role of the cryptic plasmid pAtC58 in the virulence of Agrobacterium tumefaciens strain C58. Plant Physiol., 133, 989-999.
95. Nam, J., Matthysse, A., & Gelvin, S. B. (1997). Differences in susceptibility of Arabidopsis ecotypes to crown gall disease may result from a deficiency in T-DNA integration. Plant Cell, 19, 317-333.
96. Nam, J., Mysore, K. S., Zheng, C., Knue, M. K., Matthysse, A. G., & Gelvin, G. B. (1999). Identification of T-DNA tagged Arabidopsis mutants that are resistant to transformation by Agrobacterium. Mol. Gen. Genet., 261, 429-438.
97. Narasimhulu, S. B., Deng, X.-B., Sarria, R., & Gelvin, S. B. (1996). Early transcription of Agrobacterium T-DNA genes in tobacco and maize. Plant Cell, 8, 873-886.
98. Nester, E. W., Gordon, M. P., Amasino, R. M., & Yanofsky, M. F. (1984). Crown gall: A molecular and physiological analysis Ann. Rev. Plant Physiol., 35, 387-413.
99. Peart, J. R., Cook, G., Feys, B. J., Parker, J. E., & Baulcombe, D. C. (2002). An EDS1 orthologue is required for N-mediated resistance against tobacco mosaic virus. Plant J., 29, 569-579.
100. Pemberton, L. F., Rosenblum, J. S., & Blobel, G. (1999). Nuclear import of the TATA-binding protein: mediation by the karyopherin Kap 114p and a possible mechanism for intranuclear targeting. J. Cell Biol., 145, 1407-1417.
101. Piers, K. L., Heath, J. D., Liang, X., Stephens, K. M., & Nester, E. W. (1996). Agrobacterium tumifaciens-mediated transformation of yeast. Proc. Natl. Acad. Sci., USA, 93, 1613-1618.
102. Powell, A., & Gordon, M. P. (1989). Tumor formation in plants. In A. Marcus (Ed.), The bio-chemistry of plants (Vol. 15, pp. 617-651). New York: Academic Press.
103. Powell, B. S., Rogowsky, P. M., & Kado, C. I. (1989). virG of Agrobacterium tumefaciens plasmid pTiC58 encodes a DNA-binding protein Mol. Microbiol., 3, 411-419.
104. Ream, L. W., Gordon, M. P., & Nester, E. W. (1983). Multiple mutations in the T region of the Agrobacterium tumefaciens tumor-inducing plasmid Proc. Natl. Acad. Sci., USA, 80, 1660-1664.
105. Regensburg-Tuink, A. J. G., & Hooykaas, P. J. J. (1993). Transgenic N. glauca plants expressing bacterial virulence gene virF are converted into hosts for nopaline strains of A. tumefaciens Nature, 363, 69-71.
106. Rhee, Y., Gurel, F., Gafni, Y., Dingwall, C., & Citovsky, V. (2000). A genetic system for detection of protein nuclear import and export. Nat. Biotechnol., 18, 443-437.
107. Rho, H. S., Kang, S., & Lee, Y. H. (2001). Agrobacterium tumefaciens-mediated transformation of plant pathogenic fungus, Magnaporthe grisea. Mol. Cells, 12, 407-411.
108. Riha, K., Watson, J. M., Parkey, J., & Shippen, D. E. (2002). Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. EMBO J., 21, 2819-2826.
109. Rossi, L., Hohn, B., & Tinland, B. (1993). The VirD2 protein of Agrobacterium tumefaciens carries nuclear localization signals important for transfer of T-DNA to plant. Mol. Gen. Genet., 239, 345- 353.
110. Rossi, L., Hohn, B., & Tinland, B. (1996). Integration of completed transferred DNA units is dependent on the activity of virulence E2 protein of Agrobacterium tumefaciens. Proc. Natl. Acad. Sci., USA, 93, 126-130.
111. Rout, M. P., & Wente, S. R. (1994). Pores for thought: nuclear pore complex proteins. Trends Cell. Biol., 4, 357-365.
112. Schrammeijer, B., Beijersbergen, A. G., Idler, K. B., Melchers, L. S., Thompson, D. V., & Hooykaas, P. J. (2000). Sequence analysis of the vir-region from Agrobacterium tumefaciens octopine Ti plasmid pTi15955. J. Exp. Bot., 51, 1167-1169.
113. Schrammeijer, B., den Dulk-Ras, A., Vergunst, A. C., Jurado Jacome, E., & Hooykaas, P. J. J. (2003). Analysis of Vir protein translocation from Agrobacterium tumefaciens using Saccharomyces cerevisiae as a model: Evidence for transport of a novel effector proteinVirE3. Nucl. Acids Res., 31, 860-868.
114. Schrammeijer, B., Risseeuw, E., Pansegrau, W., Regensburg-Tuink, T. J., W.L., C., & Hooykaas, P. J. J. (2001). Interaction of the virulence protein VirF of Agrobacterium tumefaciens with plant homologs of the yeast Skp1 protein. Curr. Biol., 11, 258-262.
115. Sheng, J., & Citovsky, V. (1996). Agrobacterium-plant cell DNA transport: Have virulence proteins, will travel. Plant Cell, 8, 1699-1710.
116. Shimoda, N., Toyoda-Yamamoto, A., Aoke, S., & Machida, Y. (1993). Genetic evidence for an interaction between and VirA sensor protein and the ChvE sugar-binding protein of Agrobacterium J. Biol. Chem., 268, 26552-26558.
117. Shurvinton, C. E., Hodges, L., & Ream, W. (1992). A nuclear localization signal and the C-terminal omega sequence in the Agrobacterium tumefaciens VirD2 endonuclease are important for tumor formation. Proc. Natl. Acad. Sci., USA, 89, 11837-11841.
118. Smith, E. F., & Townsend, C. O. (1907). A plant tumor of bacterial orgins. Science, 25, 671-673.
119. Stachel, S. E., Messens, E., van Montagu, M., & Zambryski, P. C. (1985). Identification of the signal molecules produced by wounded plant cell that activate T-DNA transfer in Agrobacterium tumefaciens. Nature, 318, 624-629.
120. Stachel, S. E., Nester, E. W., & Zambryski, P. C. (1986). A plant cell factor induces Agrobacterium tumefaciens vir gene expression Proc. Natl. Acad. Sci., USA, 83, 379-383.
121. Stachel, S. E., Timmerman, B., & Zambryski, P. C. (1986). Generation of single-stranded T-DNA molecules during the initial stages of T-DNA transfer from Agrobacterium tumefaciens to plant cells. Nature, 322, 706-712.
122. Stafford, H. A. (2000). Crown gall disease and Agrobacterium Tumefaciens: A study of the history, present knowlege, missing information, and impact on molecular genetics. In The Botanical Review (Vol. 66, pp. 99-118). Bronx, NY: NYBG Press.
123. Staub, J. M., Garcia, B., Graves, J., Hajdukiewicz, P. T., Hunter, P., Nehra, N., et al. (2000). High-yield production of a human therapeutic protein in tobacco chloroplasts. Nat. Biotechnol., 18, 333-338.
124. Stock, J. B., Lukat, G. S., & Stock, A. M. (1991). Bacterial chemotaxis and the molecular logic of intracellular signal transduction networks. Annu. Rev. Biophys. Chem., 20, 109-136.
125. Stock, J. B., Stock, A. M., & Mottonen, J. M. (1990). Signal transduction in bacteria. Nature, 344, 395- 400.
126. Sundberg, C., Meek, L., Carroll, K., Das, A., & Ream, W. (1996). VirE1 protein mediates export of the single-stranded DNA binding protein VirE2 from Agrobacterium tumefaciens into plant cells. J. Bacteriol., 178, 1207-1212.
127. Swart, S., Logman, T. J. J., Smit, G., Lugtenberg, B. J. J., & Kijne, J. W. (1994). Purfication and partial characterization of a glycoprotein from pea (Pisum sativum) with receptor activity for rhicadhesin, an attachment protein of Rhizobiaceae. Plant Mol. Biol., 24, 171-183.
128. Tao, Y., Rao, P. K., Bhattacharjee, S., & Gelvin, S. B. (2004). Expression of plant protein phosphatase 2C interferes with nuclear import of the Agrobacterium T-complex protein VirD2. Proc. Natl. Acad. Sci., USA, 101, 5164-5169.
129. Thomashow, M. F., Hugly, S., Buchholz, W. G., & Thomashow, L. S. (1986). Molecular basis for the auxin-independent phenotype of crown gall tumor tissues Science, 231, 616-618.
130. Tighe, S. W., de Lajudie, P., Dipietro, K., Lindstrom, K., Nick, G., & Jarvis, B. D. W. (2000). Analysis of cellular fatty acids and phenotypic relationships of Agrobacterium, Bradyhizobium, Mesorhizobium, Rhizobium and Sinorhizobium species using the Sherlock Microbial Identification System. Int. J. Syst. Evol. Microbiol., 50, 787-801.
131. Tzfira, T., & Citovsky, V. (2000). From host recognition to T-DNA integration: The function of bacterial and plant genes in the Agrobacterium-plant cell interaction. Mol. Plant. Pathol., 1, 201-121.
132. Tzfira, T., & Citovsky, V. (2001). Comaprision between nuclear import of nopaline-and octopine specific VirE2 protein of Agrobacterium on plant and animal cells. Mol. Plant Pathol., 2, 171-176.
133. Tzfira, T., & Citovsky, V. (2002). Partners-in-infection: Host proteins involved in the transformation of plant cells by Agrobacterium. Trends Cell Biol., 12, 121-129.
134. Tzfira, T., & Citovsky, V. (2003). The Agrobacterium-plant cell interaction. Taking biology lessons from a bug. Plant Physiol., 133, 943-947.
135. Tzfira, T., Li, J., Lacroix, B., & Citovsky, V. (2004). Agrobacterium T-DNA integration: molecules and models. Trends Genet., 20, 375-383.
136. Tzfira, T., Rhee, Y., Chen, M.-H., & Citovsky, V. (2000). Nucleic acid transport in plant-microbe interactions: The molecules that walk through the walls. Annu.Rev. Microbiol., 54, 187-219.
137. Tzfira, T., Rhee, Y., Chen, M.-H., Kunik, T., & Citovsky, V. (2000). Nucleic acid transport in plantmicrobe interactions: The molecules that walk through the walls. Annu. Rev. Microbiol., 54, 187- 219.
138. Tzfira, T., Vaidya, M., & Citovsky, V. (2001). VIP1, an Arabidopsis protein that interacts with Agrobacterium VirE2, is involved in VirE2 nuclear import and Agrobacterium infectivity. EMBO J., 20, 3596-3607.
139. Tzfira, T., Vaidya, M., & Citovsky, V. (2002). Increasing plant susceptibility to Agrobacterium by overexpression of the Arabidopsis nuclear protein VIP1. Proc. Natl. Acad. Sci., USA, 99, 10435- 10440.
140. Tzfira, T., Vaidya, M., & Citovsky, V. (2004). Involvement of targeted proteolysis in plant genetic transformation by Agrobacterium. Nature, 431, 87-92.
141. Uttaro, A. D., Cangelosi, G. A., Geremia, R. A., Nester, E. W., & Ugalde, R. A. (1990). Biochemical characterization of avirulent exoC mutants of Agrobacterium tumefaciens J. Bacteriol., 172, 1640- 1646.
142. van Attikum, H., Bundock, P., & Hooykaas, P. J. (2001). Non-homologous end-joining proteins are required for Agrobacterium T-DNA integration. EMBO J., 20, 6550-6558.
143. van Attikum, H., Bundock, P., Overmeer, R. M., Lee, L.-Y., Gelvin, S. B., & Hooyakaas, P. J. J. (2003). The Arabidopsis AtLIG4 gene is required for the repair of DNA damage, but not for the integration of Agrobacterium T-DNA. Nucl. Acids Res., 31, 4247-4255.
144. van Attikum, H., & Hooyakaas, P. J. J. (2003). Genetic requirements for the targeted integration of Agrobacterium T-DNA integration. EMBO J., 20, 6550-6558.
145. Van Onckelen, H., Rudelsheim, P., Inze, D., Follin, A., Messens, E., Horemans, S., et al. (1985). Tobacco plants transformed with the Agrobacterium T-DNA gene 1 contain high amounts of indole-3-acetamide FEBS Letters, 181, 373-376.
146. Veena, J. H., Doerge, R. W., & Gelvin, S. B. (2003). Transfer of T-DNA and Vir proteins to plant cells by Agrobacterium tumefaciens induces expression of host genes involved in mediating transformation and suppresses host defense gene expression. Plant J., 35, 219-226.
147. Vergunst, A. C., van Lier, M. C. M., den Dulk-Ras, A., & Hooykaas, P. J. (2003). Recognition of the Agrobacterium VirE2 translocation signal by the VirB/D4 transport system does not require VirE1. Plant Physiol, 133, 978-988.
148. Viss, W., Humann, J. L., Cook, M., Driver, J., & Ream, W. (2003). Crown-gall-resistant transgenic apple trees that silence Agrobacterium tumefaciens T-DNA oncogenes. Mol. Breeding, 12, 283- 295.
149. Wagner, V. T., & Matthysse, A. (1992). Involvement of a vitronectin-like protein in attachment of Agrobacterium tumefaciens to carrot suspension culture cells. J. Bacteriol., 174, 5999-6003.
150. Ward, E. R., & Barnes, W. M. (1988). VirD2 protein of Agrobacterium tumefaciens very tightly linked to the 5' end of T-strand DNA. Science, 242, 927-930.
151. Winans, S. C. (1991). An Agrobacterium two-component regulatory system for the detection of chemicals released from plant wounds Mol. Microbiol., 5, 2345.
152. Winans, S. C. (1992). Two-way chemical signaling in Agrobacterium-plant interactions Microbiol. Rev., 56, 12.
153. Winans, S. C., Mantis, N. J., Chen, C. Y., Chang, C. H., & Han, D. C. (1994). Host recognition by the VirA, VirG two-component regulatory proteins of Agrobacterium tumefaciens. Res. Microbiol., 145, 461-473.
154. Wood, D. W., Setubal, J. C., Kaul, R., Monks, D. E., Kitajima, J. P., Okura, V. K., et al. (2001). Science, 294, 2317-2323.
155. 2 accumulation and resistance to Phytophthora infestans. Plant Cell, 15, 706-718.
156. Young, C., & Nester, E. W. (1988). Association of the virD2 protein with the 5' end of T strands in Agrobacterium tumefaciens. J. Bacteriol., 170, 3367-3374.
157. Zambryski, P. C., Depicker, A., Kruger, K., & Goodman, H. M. (1982). Tumor induction by Agrobacterium tumefaciens: Analysis of the boundaries of T-DNA. Mol. Appl. Genet., 1, 361-370.
158. Zhou, X.-R., & Christie, P. J. (1999). Mutagenesis of the Agrobacterium VirE2 single-stranded DNAbinding protein identifies regions required for self association and interaction with VirE1 and a permissive site for hybrid protein construction. J. Bacteriol., 181, 4342-4352.
159. Zhu, J., Oger, P., Schrammeijer, B., Hooyakaas, P. J. J., Farrand, S. K., & Winans, S. C. (2000). The bases of crown gall tumorigenesis. J. Bacteriol., 182, 3885-3895.
160. Zhu, Y., Nam, J., Carpita, N. C., Matthysse, A. G., & Gelvin, S. B. (2003a). Agrobacterium-mediated root transformation is inhibited by mutation of an Arabidopsis cellulose synthase-like gene. Plant Physiol, 133, 1000-1010.
161. Zhu, Y., Nam, J., Mysore, K. S., Lee, L.-Y., Cao, H., Valentine, L., et al. (2003b). Identification of Arabidopsis rat mutants. Plant Physiol, 132, 494-505.
162. Ziemienowicz, A., Gorlich, D., Lanka, E., Hohn, B., & Rossi, L. (1999). Import of DNA into mammalian nuclei by proteins originating from a plant pathogenic bacterium. Proc. Natl. Acad. Sci., USA, 96, 3729-3733.
163. Ziemienowicz, A., Merkle, F., Schoumacher, B., Hohn, B., & Rossi, L. (2001). Import of Agrobacterium T-DNA into plant nuclei: Two distinct functions of VirD2 and VirE2 proteins. Plant Cell, 13, 369-384.
164. Zorreguieta, A., Geremia, R. A., Cavaignac, S., Cangelosi, G. A., Nester, E. W., & Ugalde, R. A. (1988). Identification of the product of anAgrobacterium tumefaciens chromosomal virulence gene. Mol. Plant-Microbe Interact., 1, 121-127.
165. Zupan, J., Citovsky, V., & Zambryski, P. C. (1996). Agrobacterium VirE2 protein mediates nuclear uptake of ssDNA in plant cells. Proc. Natl. Acad. Sci., USA, 93, 2392-2397.
166. Zupan, J., Muth, T. R., Draper, O., & Zambryski, P. C. (2000). The transfer of DNA from Agrobacterium tumefaciens into plants: A feast of fundamental insights. Plant J., 23, 11-28.
167. Zupan, J., Ward, D., & Zambryski, P. C. (1998). Assembley of the VirB transport complex for DNA transfer from Agrobacterium tumefaciens to plant cells. Curr. Opin. Microbiol., 1, 649-655.
168. Zupan, J., & Zambryski, P. C. (1995). Transfer of T-DNA from Agrobacterium to the plant cell. Plant Physiol., 107, 1041-1047.
169. Zupan, J., & Zambryski, P. C. (1997). The Agrobacterium DNA transfer complex. Crit. Rev. Plant Sci., 16, 279-2995.