메뉴 건너뛰기




Volumn 31, Issue 1, 2014, Pages 202-208

Upregulation of DNMT1 mediated by HBx suppresses RASSF1A expression independent of DNA methylation

Author keywords

DNA methylation; DNMT1; Hepatitis B virus X protein; Hepatocellular carcinoma; Ras association domain family 1A

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; HEPATITIS B VIRUS X PROTEIN; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TRANSCRIPTION FACTOR SP1; UPSTREAM STIMULATORY FACTOR;

EID: 84891950657     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2848     Document Type: Article
Times cited : (28)

References (40)
  • 1
    • 0036699940 scopus 로고    scopus 로고
    • Molecular pathogenesis of human hepatocellular carcinoma
    • Thorgeirsson SS and Grisham JW: Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31: 339-346, 2002.
    • (2002) Nat Genet , vol.31 , pp. 339-346
    • Thorgeirsson, S.S.1    Grisham, J.W.2
  • 2
    • 0034526950 scopus 로고    scopus 로고
    • Chronic hepatitis B virus infection in Asian countries
    • Merican I, Guan R, Amarapuka D, et al: Chronic hepatitis B virus infection in Asian countries. J Gastroenterol Hepatol 15: 1356-1361, 2000.
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 1356-1361
    • Merican, I.1    Guan, R.2    Amarapuka, D.3
  • 3
    • 33846473749 scopus 로고    scopus 로고
    • Hepatitis B virus-induced oncogenesis
    • Lupberger J and Hildt E: Hepatitis B virus-induced oncogenesis. World J Gastroenterol 13: 74-81, 2007.
    • (2007) World J Gastroenterol , vol.13 , pp. 74-81
    • Lupberger, J.1    Hildt, E.2
  • 4
    • 10744224746 scopus 로고    scopus 로고
    • HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice
    • Wang Y, Cui F, Lv Y, et al: HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice. Hepatology 39: 318-324, 2004.
    • (2004) Hepatology , vol.39 , pp. 318-324
    • Wang, Y.1    Cui, F.2    Lv, Y.3
  • 5
    • 21544483241 scopus 로고    scopus 로고
    • Methylation of the tumor suppressor gene RASSF1A in human tumors
    • Pfeifer GP and Dammann R: Methylation of the tumor suppressor gene RASSF1A in human tumors. Biochemistry 70: 576-583, 2005.
    • (2005) Biochemistry , vol.70 , pp. 576-583
    • Pfeifer, G.P.1    Dammann, R.2
  • 6
    • 77949658391 scopus 로고    scopus 로고
    • Clinicopathological significance of RASSF1A reduced expression and hypermethylation in hepatocellular carcinoma
    • Hu L, Chen G, Yu H and Qiu X: Clinicopathological significance of RASSF1A reduced expression and hypermethylation in hepatocellular carcinoma. Hepatol Int 4: 423-432, 2010.
    • (2010) Hepatol Int , vol.4 , pp. 423-432
    • Hu, L.1    Chen, G.2    Yu, H.3    Qiu, X.4
  • 7
    • 0037468934 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma
    • Schagdarsurengin U, Wilkens L, Steinemann D, et al: Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene 22: 1866-1871, 2003.
    • (2003) Oncogene , vol.22 , pp. 1866-1871
    • Schagdarsurengin, U.1    Wilkens, L.2    Steinemann, D.3
  • 8
    • 0041695472 scopus 로고    scopus 로고
    • Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas
    • Zhong S, Yeo W, Tang MW, Wong N, Lai PB and Johnson PJ: Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas. Clin Cancer Res 9: 3376-3382, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 3376-3382
    • Zhong, S.1    Yeo, W.2    Tang, M.W.3    Wong, N.4    Lai, P.B.5    Johnson, P.J.6
  • 9
    • 7044260782 scopus 로고    scopus 로고
    • Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: Old and new paradigms
    • Bréchot C: Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms. Gastroenterology 127 (Suppl 1): S56-S61, 2004.
    • (2004) Gastroenterology , vol.127 , Issue.SUPPL. 1
    • Bréchot, C.1
  • 10
    • 0025907983 scopus 로고
    • HBx gene of hepatitis B virus induces liver cancer in transgenic mice
    • Kim CM, Koike K, Saito I, Miyamura T and Jay G: HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 351: 317-320, 1991.
    • (1991) Nature , vol.351 , pp. 317-320
    • Kim, C.M.1    Koike, K.2    Saito, I.3    Miyamura, T.4    Jay, G.5
  • 11
    • 0033058294 scopus 로고    scopus 로고
    • Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein
    • Yu DY, Moon HB, Son JK, et al: Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein. J Hepatol 31: 123-132, 1999.
    • (1999) J Hepatol , vol.31 , pp. 123-132
    • Yu, D.Y.1    Moon, H.B.2    Son, J.K.3
  • 12
    • 34247190634 scopus 로고    scopus 로고
    • Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein
    • Park IY, Sohn BH, Yu E, et al: Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology 132: 1476-1494, 2007.
    • (2007) Gastroenterology , vol.132 , pp. 1476-1494
    • Park, I.Y.1    Sohn, B.H.2    Yu, E.3
  • 13
    • 61849154030 scopus 로고    scopus 로고
    • Proteomic profiling identifies aberrant epigenetic modifications induced by hepatitis B virus X protein
    • Tong A, Gou L, Lau QC, et al: Proteomic profiling identifies aberrant epigenetic modifications induced by hepatitis B virus X protein. J Proteome Res 8: 1037-1046, 2009.
    • (2009) J Proteome Res , vol.8 , pp. 1037-1046
    • Tong, A.1    Gou, L.2    Lau, Q.C.3
  • 14
    • 58149310908 scopus 로고    scopus 로고
    • Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A
    • Zheng DL, Zhang L, Cheng N, et al: Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A. J Hepatol 50: 377-387, 2009.
    • (2009) J Hepatol , vol.50 , pp. 377-387
    • Zheng, D.L.1    Zhang, L.2    Cheng, N.3
  • 15
    • 27144448810 scopus 로고    scopus 로고
    • Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1
    • Lee JO, Kwun HJ, Jung JK, Choi KH, Min DS and Jang KL: Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1. Oncogene 24: 6617-6625, 2005.
    • (2005) Oncogene , vol.24 , pp. 6617-6625
    • Lee, J.O.1    Kwun, H.J.2    Jung, J.K.3    Choi, K.H.4    Min, D.S.5    Jang, K.L.6
  • 16
    • 78249232586 scopus 로고    scopus 로고
    • INK4A promoter through upregulation of DNA methyltransferases in hepatocarcinogenesis
    • INK4A promoter through upregulation of DNA methyltransferases in hepatocarcinogenesis. Exp Mol Pathol 89: 268-275, 2010.
    • (2010) Exp Mol Pathol , vol.89 , pp. 268-275
    • Zhu, Y.1    Zhu, R.2    Shi, L.3
  • 17
    • 37349036468 scopus 로고    scopus 로고
    • DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721
    • Fan H, Zhao Z, Quan Y, Xu J, Zhang J and Xie W: DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721. Eur J Gastroenterol Hepatol 19: 952-961, 2007.
    • (2007) Eur J Gastroenterol Hepatol , vol.19 , pp. 952-961
    • Fan, H.1    Zhao, Z.2    Quan, Y.3    Xu, J.4    Zhang, J.5    Xie, W.6
  • 18
    • 28644433852 scopus 로고    scopus 로고
    • Identification of potential genes regulated by DNA methyltransferase 3B in a hepatocellular carcinoma cell line by RNA interference and microarray analysis
    • In Chinese
    • Xu J, Fan H, Zhao ZJ, Zhang JQ and Xie W: Identification of potential genes regulated by DNA methyltransferase 3B in a hepatocellular carcinoma cell line by RNA interference and microarray analysis. Yi Chuan Xue Bao 32: 1115-1127, 2005 (In Chinese).
    • (2005) Yi Chuan Xue Bao , vol.32 , pp. 1115-1127
    • Xu, J.1    Fan, H.2    Zhao, Z.J.3    Zhang, J.Q.4    Xie, W.5
  • 19
    • 0036712913 scopus 로고    scopus 로고
    • Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells
    • Tao Q, Huang H, Geiman TM, et al: Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum Mol Genet 11: 2091-2102, 2002.
    • (2002) Hum Mol Genet , vol.11 , pp. 2091-2102
    • Tao, Q.1    Huang, H.2    Geiman, T.M.3
  • 20
    • 32844460417 scopus 로고    scopus 로고
    • DNA hypermethylation status of multiple genes in soft tissue sarcomas
    • Kawaguchi Ki, Oda Y, Saito T, et al: DNA hypermethylation status of multiple genes in soft tissue sarcomas. Mod Pathol 19: 106-114, 2006.
    • (2006) Mod Pathol , vol.19 , pp. 106-114
    • Ki, K.1    Oda, Y.2    Saito, T.3
  • 21
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S and Pfeifer GP: Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet 25: 315-319, 2000.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 22
    • 77951176116 scopus 로고    scopus 로고
    • CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
    • Chen L, Chan THM, Yuan YF, et al: CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. J Clin Invest 120: 1178-1191, 2010.
    • (2010) J Clin Invest , vol.120 , pp. 1178-1191
    • Chen, L.1    Chan, T.H.M.2    Yuan, Y.F.3
  • 23
    • 0141954011 scopus 로고    scopus 로고
    • Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer
    • Yan PS, Shi H, Rahmatpanah F, et al: Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer. Cancer Res 63: 6178-6186, 2003.
    • (2003) Cancer Res , vol.63 , pp. 6178-6186
    • Yan, P.S.1    Shi, H.2    Rahmatpanah, F.3
  • 24
    • 19944429131 scopus 로고    scopus 로고
    • Tumor susceptibility of Rassf1a knockout mice
    • Tommasi S, Dammann R, Zhang Z, et al: Tumor susceptibility of Rassf1a knockout mice. Cancer Res 65: 92-98, 2005.
    • (2005) Cancer Res , vol.65 , pp. 92-98
    • Tommasi, S.1    Dammann, R.2    Zhang, Z.3
  • 25
    • 0035795676 scopus 로고    scopus 로고
    • Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression
    • Burbee DG, Forgacs E, Zöchbauer-Müller S, et al: Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Natl Cancer Inst 93: 691-699, 2001.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 691-699
    • Burbee, D.G.1    Forgacs, E.2    Zöchbauer-Müller, S.3
  • 26
    • 1842536844 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas
    • Hesson L, Bièche I, Krex D, et al: Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas. Oncogene 23: 2408-2419, 2004.
    • (2004) Oncogene , vol.23 , pp. 2408-2419
    • Hesson, L.1    Bièche, I.2    Krex, D.3
  • 27
    • 0035912820 scopus 로고    scopus 로고
    • The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis
    • Dreijerink K, Braga E, Kuzmin I, et al: The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. Proc Natl Acad Sci USA 98: 7504-7509, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7504-7509
    • Dreijerink, K.1    Braga, E.2    Kuzmin, I.3
  • 28
    • 0037096818 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
    • Kuzmin I, Gillespie JW, Protopopov A, et al: The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells. Cancer Res 62: 3498-3502, 2002.
    • (2002) Cancer Res , vol.62 , pp. 3498-3502
    • Kuzmin, I.1    Gillespie, J.W.2    Protopopov, A.3
  • 29
    • 2442482316 scopus 로고    scopus 로고
    • RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma
    • Chow LS, Lo KW, Kwong J, et al: RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma. Int J Cancer 109: 839-847, 2004.
    • (2004) Int J Cancer , vol.109 , pp. 839-847
    • Chow, L.S.1    Lo, K.W.2    Kwong, J.3
  • 30
    • 4043131815 scopus 로고    scopus 로고
    • Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene
    • Li J, Wang F, Protopopov A, et al: Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene. Oncogene 23: 5941-5949, 2004.
    • (2004) Oncogene , vol.23 , pp. 5941-5949
    • Li, J.1    Wang, F.2    Protopopov, A.3
  • 31
  • 32
    • 0033945861 scopus 로고    scopus 로고
    • DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    • Rountree MR, Bachman KE and Baylin SB: DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet 25: 269-277, 2000.
    • (2000) Nat Genet , vol.25 , pp. 269-277
    • Rountree, M.R.1    Bachman, K.E.2    Baylin, S.B.3
  • 33
    • 0033919595 scopus 로고    scopus 로고
    • DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
    • Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL and Wolffe AP: DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 25: 338-342, 2000.
    • (2000) Nat Genet , vol.25 , pp. 338-342
    • Robertson, K.D.1    Ait-Si-Ali, S.2    Yokochi, T.3    Wade, P.A.4    Jones, P.L.5    Wolffe, A.P.6
  • 34
    • 0024083068 scopus 로고
    • Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated
    • Höller M, Westin G, Jiricny J and Schaffner W: Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev 2: 1127-1135, 1988.
    • (1988) Genes Dev , vol.2 , pp. 1127-1135
    • Höller, M.1    Westin, G.2    Jiricny, J.3    Schaffner, W.4
  • 35
    • 0029933660 scopus 로고    scopus 로고
    • Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene
    • Pieper RO, Patel S, Ting SA, Futscher BW and Costello JF: Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene. J Biol Chem 271: 13916-13924, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 13916-13924
    • Pieper, R.O.1    Patel, S.2    Ting, S.A.3    Futscher, B.W.4    Costello, J.F.5
  • 36
    • 18144415066 scopus 로고    scopus 로고
    • Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter
    • Strunnikova M, Schagdarsurengin U, Kehlen A, Garbe JC, Stampfer MR and Dammann R: Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter. Mol Cell Biol 25: 3923-3933, 2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 3923-3933
    • Strunnikova, M.1    Schagdarsurengin, U.2    Kehlen, A.3    Garbe, J.C.4    Stampfer, M.R.5    Dammann, R.6
  • 37
    • 0022374891 scopus 로고
    • Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region
    • Sawadogo M and Roeder RG: Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region. Cell 43: 165-175, 1985.
    • (1985) Cell , vol.43 , pp. 165-175
    • Sawadogo, M.1    Roeder, R.G.2
  • 38
    • 0029868498 scopus 로고    scopus 로고
    • Functional domains of the transcription factor USF2: Atypical nuclear localization signals and context-dependent transcriptional activation domains
    • Luo X and Sawadogo M: Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains. Mol Cell Biol 16: 1367-1375, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 1367-1375
    • Luo, X.1    Sawadogo, M.2
  • 39
    • 0030695247 scopus 로고    scopus 로고
    • Cloning of an inr-and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1
    • Roy AL, Du H, Gregor PD, Novina CD, Martinez E and Roeder RG: Cloning of an inr-and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. EMBO J 16: 7091-7104, 1997.
    • (1997) EMBO J , vol.16 , pp. 7091-7104
    • Roy, A.L.1    Du, H.2    Gregor, P.D.3    Novina, C.D.4    Martinez, E.5    Roeder, R.G.6
  • 40
    • 0033523885 scopus 로고    scopus 로고
    • Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation
    • Majumder S, Ghoshal K, Li Z, Bo Y and Jacob ST: Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation. Oncogene 18: 6287-6295, 1999.
    • (1999) Oncogene , vol.18 , pp. 6287-6295
    • Majumder, S.1    Ghoshal, K.2    Li, Z.3    Bo, Y.4    Jacob, S.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.