Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis

EMBO Molecular Medicine

Volumn 6, Issue 1, 2014, Pages 27-42

  Dalli, Jesmond ^a,d   Norling, Lucy V ^a   Montero Melendez, Trinidad ^a   Canova, Donata Federici ^a   Lashin, Hazem ^a   Pavlov, Anton M ^b   Sukhorukov, Gleb B ^b   Hinds, Charles J ^a,c   Perretti, Mauro ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Activation; Innate immunity; Lipoprotein receptor related protein 1; Neutrophil; Phagocytosis

Indexed keywords

ALPHA 2 MACROGLOBULIN; CATHELICIDIN; CHEMOKINE RECEPTOR CXCR2; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; CELL MEMBRANE; CYTOKINE RELEASE; DOWN REGULATION; ENDOTHELIUM CELL; EXUDATE; HUMAN; HUMAN CELL; HYPOTHERMIA; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; LEUKOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SEPSIS;

ALPHA-MACROGLOBULINS; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CYTOPLASMIC VESICLES; ESCHERICHIA COLI; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; KAPLAN-MEIER ESTIMATE; LEUKOCYTES; LIPOPOLYSACCHARIDES; MALE; MICE; MICROSPHERES; NEUTROPHILS; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-8B; SEPSIS;

EID: 84891948860     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201303503     Document Type: Article

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