-
1
-
-
41149115123
-
The role of oxygen availability in embryonic development and stem cell function
-
Simon MC, Keith B (2008) The role of oxygen availability in embryonic development and stem cell function. Nat Rev Mol Cell Biol 9(4): 285-296.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.4
, pp. 285-296
-
-
Simon, M.C.1
Keith, B.2
-
2
-
-
67651146522
-
Neoadjuvant chemotherapy and radiotherapy followed by surgery in selected patients with stage IIIB non-small-cell lung cancer: A multicentre phase II trial
-
Stupp R, et al. (2009) Neoadjuvant chemotherapy and radiotherapy followed by surgery in selected patients with stage IIIB non-small-cell lung cancer: A multicentre phase II trial. Lancet Oncol 10(8): 785-793.
-
(2009)
Lancet Oncol
, vol.10
, Issue.8
, pp. 785-793
-
-
Stupp, R.1
-
3
-
-
0842325802
-
Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population
-
Brat DJ, et al. (2004) Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res 64(3): 920-927.
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 920-927
-
-
Brat, D.J.1
-
4
-
-
84860247330
-
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma
-
Cooper LA, et al. (2012) The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. Am J Pathol 180(5): 2108-2119.
-
(2012)
Am J Pathol
, vol.180
, Issue.5
, pp. 2108-2119
-
-
Cooper, L.A.1
-
5
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, et al. (2006) Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9(3): 157-173.
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 157-173
-
-
Phillips, H.S.1
-
6
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Cancer Genome Atlas Research Network
-
Verhaak RG, et al.; Cancer Genome Atlas Research Network (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17(1): 98-110.
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
-
7
-
-
33645294070
-
Oncomirs - MicroRNAs with a role in cancer
-
Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6(4): 259-269.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.4
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
9
-
-
48949116262
-
MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
-
Silber J, et al. (2008) miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 6:14.
-
(2008)
BMC Med
, vol.6
, pp. 14
-
-
Silber, J.1
-
10
-
-
56449126945
-
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
-
Godlewski J, et al. (2008) Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68(22): 9125-9130.
-
(2008)
Cancer Res
, vol.68
, Issue.22
, pp. 9125-9130
-
-
Godlewski, J.1
-
11
-
-
33847234988
-
A microRNA signature of hypoxia
-
Kulshreshtha R, et al. (2007) A microRNA signature of hypoxia. Mol Cell Biol 27(5): 1859-1867.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.5
, pp. 1859-1867
-
-
Kulshreshtha, R.1
-
12
-
-
77958516991
-
MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma
-
Davidson MR, et al. (2010) MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma. PLoS ONE 5(9):e12560.
-
(2010)
PLoS ONE
, vol.5
, Issue.9
-
-
Davidson, M.R.1
-
13
-
-
77950428314
-
MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor
-
Tie J, et al. (2010) MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. PLoS Genet 6(3):e1000879.
-
(2010)
PLoS Genet
, vol.6
, Issue.3
-
-
Tie, J.1
-
14
-
-
12344317031
-
Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers
-
Dickinson RE, et al. (2004) Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers. Br J Cancer 91(12): 2071-2078.
-
(2004)
Br J Cancer
, vol.91
, Issue.12
, pp. 2071-2078
-
-
Dickinson, R.E.1
-
15
-
-
0043170818
-
Frequent epigenetic inactivation of the SLIT2 gene in gliomas
-
Dallol A, et al. (2003) Frequent epigenetic inactivation of the SLIT2 gene in gliomas. Oncogene 22(29): 4611-4616.
-
(2003)
Oncogene
, vol.22
, Issue.29
, pp. 4611-4616
-
-
Dallol, A.1
-
16
-
-
4644313275
-
Gene expression profiling of gliomas strongly predicts survival
-
Freije WA, et al. (2004) Gene expression profiling of gliomas strongly predicts survival. Cancer Res 64(18): 6503-6510.
-
(2004)
Cancer Res
, vol.64
, Issue.18
, pp. 6503-6510
-
-
Freije, W.A.1
-
17
-
-
78650163455
-
Gene expression profiles of human glioblastomas are associated with both tumor cytogenetics and histopathology
-
Vital AL, et al. (2010) Gene expression profiles of human glioblastomas are associated with both tumor cytogenetics and histopathology. Neuro-oncol 12(9): 991-1003.
-
(2010)
Neuro-oncol
, vol.12
, Issue.9
, pp. 991-1003
-
-
Vital, A.L.1
-
18
-
-
79957905986
-
Molecular subclassification of diffuse gliomas: Seeing order in the chaos
-
Huse JT, Phillips HS, Brennan CW (2011) Molecular subclassification of diffuse gliomas: Seeing order in the chaos. Glia 59(8): 1190-1199.
-
(2011)
Glia
, vol.59
, Issue.8
, pp. 1190-1199
-
-
Huse, J.T.1
Phillips, H.S.2
Brennan, C.W.3
-
19
-
-
33749366427
-
Primary glioblastomas express mesenchymal stem-like properties
-
Tso CL, et al. (2006) Primary glioblastomas express mesenchymal stem-like properties. Mol Cancer Res 4(9): 607-619.
-
(2006)
Mol Cancer Res
, vol.4
, Issue.9
, pp. 607-619
-
-
Tso, C.L.1
-
20
-
-
79952751773
-
MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway
-
Alajez NM, et al. (2011) MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res 71(6): 2381-2391.
-
(2011)
Cancer Res
, vol.71
, Issue.6
, pp. 2381-2391
-
-
Alajez, N.M.1
-
21
-
-
84875716955
-
MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity
-
Xia H, et al. (2013) MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity. Neuro-oncol 15(4): 413-422.
-
(2013)
Neuro-oncol
, vol.15
, Issue.4
, pp. 413-422
-
-
Xia, H.1
-
22
-
-
79959969874
-
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
-
Eyler CE, et al. (2011) Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 146(1): 53-66.
-
(2011)
Cell
, vol.146
, Issue.1
, pp. 53-66
-
-
Eyler, C.E.1
-
23
-
-
78449308794
-
Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria
-
Gdynia G, et al. (2010) Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria. Cancer Res 70(21): 8558-8568.
-
(2010)
Cancer Res
, vol.70
, Issue.21
, pp. 8558-8568
-
-
Gdynia, G.1
-
24
-
-
33845905487
-
Cytolytic cells induce HMGB1 release from melanoma cell lines
-
Ito N, et al. (2007) Cytolytic cells induce HMGB1 release from melanoma cell lines. J Leukoc Biol 81(1): 75-83.
-
(2007)
J Leukoc Biol
, vol.81
, Issue.1
, pp. 75-83
-
-
Ito, N.1
-
25
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418(6894): 191-195.
-
(2002)
Nature
, vol.418
, Issue.6894
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
26
-
-
57649217868
-
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
-
Thorburn J, et al. (2009) Autophagy regulates selective HMGB1 release in tumor cells that are destined to die. Cell Death Differ 16(1): 175-183.
-
(2009)
Cell Death Differ
, vol.16
, Issue.1
, pp. 175-183
-
-
Thorburn, J.1
-
27
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, et al. (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352(10): 997-1003.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
-
28
-
-
78650069506
-
Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain
-
Oliva CR, et al. (2010) Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. J Biol Chem 285(51): 39759-39767.
-
(2010)
J Biol Chem
, vol.285
, Issue.51
, pp. 39759-39767
-
-
Oliva, C.R.1
-
29
-
-
84883656941
-
Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma
-
Bhat KP, et al. (2013) Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma. Cancer Cell 24(3): 331-346.
-
(2013)
Cancer Cell
, vol.24
, Issue.3
, pp. 331-346
-
-
Bhat, K.P.1
-
30
-
-
0037432190
-
Requirement of autophosphorylated tyrosine 992 of EGF receptor and its docking protein phospholipase C gamma 1 for membrane ruffle formation
-
Nogami M, et al. (2003) Requirement of autophosphorylated tyrosine 992 of EGF receptor and its docking protein phospholipase C gamma 1 for membrane ruffle formation. FEBS Lett 536(1-3): 71-76.
-
(2003)
FEBS Lett
, vol.536
, Issue.1-3
, pp. 71-76
-
-
Nogami, M.1
-
31
-
-
78649753178
-
PI3KC2α, a class II PI3K, is required for dynamin-independent internalization pathways
-
Krag C, Malmberg EK, Salcini AE (2010) PI3KC2α, a class II PI3K, is required for dynamin-independent internalization pathways. J Cell Sci 123(Pt 24): 4240-4250.
-
(2010)
J Cell Sci
, vol.123
, Issue.PART 24
, pp. 4240-4250
-
-
Krag, C.1
Malmberg, E.K.2
Salcini, A.E.3
-
32
-
-
45949107072
-
Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma
-
Chakraborty S, Mohiyuddin SM, Gopinath KS, Kumar A (2008) Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma. BMC Cancer 8:163.
-
(2008)
BMC Cancer
, vol.8
, pp. 163
-
-
Chakraborty, S.1
Mohiyuddin, S.M.2
Gopinath, K.S.3
Kumar, A.4
-
33
-
-
84879695087
-
ARAF acts as a scaffold to stabilize BRAF:CRAF heterodimers
-
Rebocho AP, Marais R (2013) ARAF acts as a scaffold to stabilize BRAF:CRAF heterodimers. Oncogene 32(26): 3207-3212.
-
(2013)
Oncogene
, vol.32
, Issue.26
, pp. 3207-3212
-
-
Rebocho, A.P.1
Marais, R.2
-
34
-
-
84866920135
-
Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1
-
Chou CW, et al. (2012) Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1. Neurooncol 14(10): 1227-1238.
-
(2012)
Neurooncol
, vol.14
, Issue.10
, pp. 1227-1238
-
-
Chou, C.W.1
-
35
-
-
79959928027
-
Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids
-
Kolenda J, et al. (2011) Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids. J Neurooncol 103(1): 43-58.
-
(2011)
J Neurooncol
, vol.103
, Issue.1
, pp. 43-58
-
-
Kolenda, J.1
-
36
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z, et al. (2009) Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15(6): 501-513.
-
(2009)
Cancer Cell
, vol.15
, Issue.6
, pp. 501-513
-
-
Li, Z.1
-
37
-
-
36949007159
-
Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha
-
Lu Y, Liang K, Li X, Fan Z (2007) Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha. Mol Cancer 6:63.
-
(2007)
Mol Cancer
, vol.6
, pp. 63
-
-
Lu, Y.1
Liang, K.2
Li, X.3
Fan, Z.4
-
38
-
-
77952238683
-
Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells
-
Xu L, et al. (2010) Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells. Oncogene 29(18): 2616-2627.
-
(2010)
Oncogene
, vol.29
, Issue.18
, pp. 2616-2627
-
-
Xu, L.1
-
39
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
Zhong H, et al. (2000) Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res 60(6): 1541-1545.
-
(2000)
Cancer Res
, vol.60
, Issue.6
, pp. 1541-1545
-
-
Zhong, H.1
-
40
-
-
84856159550
-
C-Jun, at the crossroad of the signaling network
-
Meng Q, Xia Y (2011) c-Jun, at the crossroad of the signaling network. Protein Cell 2(11): 889-898.
-
(2011)
Protein Cell
, vol.2
, Issue.11
, pp. 889-898
-
-
Meng, Q.1
Xia, Y.2
-
41
-
-
84868612850
-
Hypoxia-induced angiogenesis: Good and evil
-
Krock BL, Skuli N, Simon MC (2011) Hypoxia-induced angiogenesis: Good and evil. Genes Cancer 2(12): 1117-1133.
-
(2011)
Genes Cancer
, vol.2
, Issue.12
, pp. 1117-1133
-
-
Krock, B.L.1
Skuli, N.2
Simon, M.C.3
-
42
-
-
67651098992
-
Endothelial deletion of hypoxia-inducible factor-2alpha (HIF- 2alpha) alters vascular function and tumor angiogenesis
-
Skuli N, et al. (2009) Endothelial deletion of hypoxia-inducible factor-2alpha (HIF- 2alpha) alters vascular function and tumor angiogenesis. Blood 114(2): 469-477.
-
(2009)
Blood
, vol.114
, Issue.2
, pp. 469-477
-
-
Skuli, N.1
-
43
-
-
84859700702
-
Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes
-
Skuli N, et al. (2012) Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes. J Clin Invest 122(4): 1427-1443.
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1427-1443
-
-
Skuli, N.1
-
44
-
-
84875755046
-
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
-
Cheng L, et al. (2013) Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell 153(1): 139-152.
-
(2013)
Cell
, vol.153
, Issue.1
, pp. 139-152
-
-
Cheng, L.1
|