Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria

Cancer Research

Volumn 70, Issue 21, 2010, Pages 8558-8568

  Gdynia, Georg ^a   Keith, Martina ^a   Kopitz, Jürgen ^a   Bergmann, Marion ^a   Fassl, Anne ^a   Weber, Alexander N R ^a   George, Julie ^a   Kees, Tim ^a   Zentgraf, Hans Walter ^a   Wiestler, Otmar D ^a   Schirmacher, Peter ^a   Roth, Wilfried ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; HIGH MOBILITY GROUP B1 PROTEIN; PROTEOME; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TEMOZOLOMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; CANCER CELL; CELL DEATH; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; ASTROCYTES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FREE RADICAL SCAVENGERS; GLIOBLASTOMA; HMGB1 PROTEIN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NECROSIS; PROTEOME; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 78449308794     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-0204     Document Type: Article

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