SuperBiHelix method for predicting the pleiotropic ensemble of G-protein-coupled receptor conformation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 1, 2014, Pages

  Bray, Jenelle K ^a,b   Abrol, Ravinder ^a,c   Goddard III, William A ^a   Trzaskowski, Bartosz ^a,d   Scott, Caitlin E ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b STANFORD UNIVERSITY   (United States)

^c CEDARS SINAI MEDICAL CENTER   (United States)

^d UNIVERSITY OF WARSAW   (Poland)

Author keywords

2 adrenergic receptor; A2A adenosine receptor; Constitutive activity; Functional selectivity; Protein structure prediction

Indexed keywords

CANNABINOID 1 RECEPTOR; G PROTEIN COUPLED RECEPTOR;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DOCKING; PLEIOTROPY; PRIORITY JOURNAL; PROCEDURES; PROTEIN CONFORMATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; SUPERBIHELIX METHOD;

A2A ADENOSINE RECEPTOR; CONSTITUTIVE ACTIVITY; FUNCTIONAL SELECTIVITY; PROTEIN STRUCTURE PREDICTION; Β2-ADRENERGIC RECEPTOR;

ALGORITHMS; BINDING SITES; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, ADENOSINE A2A; RECEPTOR, CANNABINOID, CB1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SOFTWARE;

EID: 84891928230     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321233111     Document Type: Article

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