Antisense oligonucleotide-stimulated transcriptional pausing reveals RNA exit channel specificity of RNA polymerase and mechanistic contributions of NusA and RfaH

Journal of Biological Chemistry

Volumn 289, Issue 2, 2014, Pages 1151-1163

  Kolb, Kellie E ^a   Hein, Pyae P ^a   Landick, Robert ^a,b  

^a Department of Biochemistry ^*  (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE; ANTISENSE RNA; BACTERIAL TRANSCRIPTION; DNA OLIGONUCLEOTIDES; RNA POLYMERASE; RNA STRUCTURES;

OLIGONUCLEOTIDES;

RNA;

ANTISENSE OLIGODEOXYNUCLEOTIDE; BACTERIAL RNA; COMPLEMENTARY RNA; DOUBLE STRANDED DNA; DOUBLE STRANDED RNA; ELONGATION FACTOR; ELONGATION FACTOR NUSA; ELONGATION FACTOR RFAH; RNA POLYMERASE; SHORT HAIRPIN RNA; SINGLE STRANDED RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CONCENTRATION (PARAMETERS); DNA FLANKING REGION; DNA RNA HYBRIDIZATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEIC ACID STRUCTURE; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA CONFORMATION; RNA STABILITY; TRANSCRIPTION ELONGATION; TRANSCRIPTION PAUSING;

BACTERIAL TRANSCRIPTION; GENE EXPRESSION; GENE REGULATION; NUSA; RFAH; RNA POLYMERASE; TRANSCRIPTION; TRANSCRIPTION FACTORS; TRANSCRIPTION REGULATION; TRANSCRIPTIONAL PAUSING;

DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, GENETIC; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDE ELONGATION FACTORS; RNA, BACTERIAL; RNA, DOUBLE-STRANDED; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84891910083     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.521393     Document Type: Article

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