Protective effect of phosphatidylcholine on restoration of ethanol-injured hepatocytes related with caveolin-1

Journal of Membrane Biology

Volumn 247, Issue 1, 2014, Pages 73-80

  Zhang, Yuan ^a,d   Zou, Wei ^a,c   Cui, Fenggong ^a   Wang, Nan ^a,e   Zhang, Dongyan ^a,c   Cui, Yuying ^a   Liu, Peng ^b   Liu, Jing ^b  

^a LIAONING NORMAL UNIVERSITY   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c Liaoning Provincial Key Laboratory of Biotechnology and Drug Discovery   (China)

^d JILIN UNIVERSITY   (China)

^e Sixth People's Hospital of Dalian   (China)

Author keywords

Caveolin 1; Ethanol injury; Phosphatidylcholine; Protective effect

Indexed keywords

ALCOHOL; CAVEOLIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLCHOLINE; PROTEIN KINASE C ALPHA;

ABSORPTION; ARTICLE; CELL PROLIFERATION; CONDUCTANCE; CONTROLLED STUDY; DOWN REGULATION; ELECTRIC CONDUCTIVITY; ENVIRONMENTAL STRESS; ENZYME ACTIVITY; GENE SILENCING; IMMUNOBLOTTING; LIPID PEROXIDATION; LIVER CELL; LIVER PROTECTION; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; CAVEOLIN 1; ETHANOL; GENE EXPRESSION REGULATION; HEPATOCYTES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLCHOLINES; PLASMALOGENS; PROTECTIVE AGENTS; PROTEIN KINASE C-ALPHA; SWINE;

EID: 84891890976     PISSN: 00222631     EISSN: 14321424     Source Type: Journal    
DOI: 10.1007/s00232-013-9613-0     Document Type: Article

References (34)

1. Aleynik MK, Lieber CS (2001) Dilinoleoylphosphatidylcholine decreases ethanol-induced cytochrome P4502E1. Biochem Biophys Res Commun 288:1047-1051 (Pubitemid 33140991)
2. Aleynik MK, Leo MA, Aleynik SI et al (1999) Polyenylphosphatidylcholine opposes the increase of cytochrome P24502E1 by ethanol and corrects its iron-induced decrease. Alcohol Clin Exp Res 23:96-100 (Pubitemid 29068471)
3. Bishop WR, Bell RM (1988) Assembly of phospholipids into cellular membranes: biosynthesis, transmembrane movement and intracellular translocation. Annu Rev Cell Biol 4:579-610 (Pubitemid 19139267)
4. Cao Q, Mak KM, Lieber CS (2002a) Dilinoleoylphosphatidylcholine decreases acetaldehyde induced TNF-α generation in Kupffer cells of ethanol-fed rats. Biochem Biophys Res Commun 299:459-464 (Pubitemid 35365651)
5. Cao Q, Mak KM, Lieber CS (2002b) Dilinoleoylphosphatidylcholine decreases LPS2 induced TNF-α generation in Kupffer cells of ethanol-fed rats: respective roles of MAPKs and NF-κB. Biochem Biophys Res Commun 294:849-853 (Pubitemid 34687194)
6. Cohen AW, Razani B, Schubert W et al (2004) Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation. Diabetes 53:1261-1270 (Pubitemid 38569012)
7. Fataccioli V (2004) Effects of chronic ethanol administration on rat liver proteasome activities: relationship with oxidative stress. Hepatology 34:14-20
8. Fernandez MA, Albor C, Ingelmo-Torres M et al (2006) Cav-1 is essential for liver regeneration. Science 313(5793):1628-1632 (Pubitemid 44414035)
9. Folch J, Lee MB, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226:497-509
10. Fujimoto T, Kogo H, Ishiguro K, Tauchi K, Nomura R (2001) Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell. J Cell Biol 152:1079-1085 (Pubitemid 34286082)
11. Hou CY, Zhao DY, Cao Y, Wang DS (2010) Protective effects of soybean phospholipid liposomes on neonatal rat hepatocytes induced by carbon tetrachloride. China J Modern Med 20:3716-3719
12. Ito J et al (2002) Apolipoprotein A-I induces translocation of cholesterol, phospholipid, and caveolin-1 to cytosol in rat astrocytes. J Biol Chem 277:7929-7935 (Pubitemid 34968243)
13. Kidd PM (2000) Dietary phospholipids as anti-aging nutraceuticals. In: Klatz RA, Goldman R (eds) Anti-aging medical therapeutics. Health Quest Publications, Chicago, pp 83-301
14. Kurzchalia TV, Parton RG (1999) Membrane microdomains and caveolae. Curr Opin Cell Biol 11:424-431 (Pubitemid 29396787)
15. Li J, Hassan GS, Williams TM et al (2005) Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation. Cell Cycle 4:1817-1825 (Pubitemid 41827329)
16. Mak KM, Wen KF, Ren CL et al (2003) Dilinoleoylphosphatidylcholine reproduces the antiapoptotic actions of polyenylphosphatidylcholine against ethanol-induced hepatocyte apoptosis. Alcohol Clin Exp Res 27:997-1005 (Pubitemid 36759390)
17. Morrison K, Witte K, Mayers JR, Schuh AL, Audhya A (2012) Roles of acidic phospholipids and nucleotides in regulating membrane binding and activity of a calcium-independent phospholipase A2 Isoform J. Biol Chem 287:38824-38834
18. Ostermeyer AG, Paci JM, Zeng Y, Lublin DM, Munro S, Brown DA (2001) Accumulation of caveolin in the endoplasmic reticulum redirects the protein to lipid storage droplets. J Cell Biol 152:1071-1078 (Pubitemid 34286081)
19. Parton RG (2007) The multiple faces of caveolae. Nat Rev Mol Cell Biol 8:185-194
20. Pol A, Luetterforst R, Lindsay M, Heino S, Ikonen E, Parton RGA (2001) Caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance. J Cell Biol 152:1057-1070 (Pubitemid 34286080)
21. Regente M, Corti Monzón G, de la Canal L (2008) Phospholipids are present in extracellular fluids of imbibing sunflower seeds and are modulated by hormonal treatments. J Exp Bot 59:553-562 (Pubitemid 351640733)
22. Ren G, Liu Y, Wang XM, Zhao CH, Zou W (2008) Role of caveolin-1 down-regulation by iRNA in human hepatocyte proliferation. Chin J Hepatol 16:379-382
23. Seo HR, Kwan YW, Cho CK, Bae S, Lee SJ, Soh JW, Chung HY, Lee YS (2004) PKCalpha induces differentiation through ERK1/2 phosphorylation in mouse keratinocytes. Exp Mol Med 36:292-299 (Pubitemid 39279525)
24. Sergent O, Pereira M, Belhomme C et al (2005) Role for membrane fluidity in ethanol-induced oxidative stress of primary rat hepatocytes. J Pharmacol Exp Ther 1:5
25. Stewart SF, Vidali M, Day CP et al (2004) Oxidative stress as a trigger for cellular responses in patients with ethanolic liver disease. Hepatology 39:197-203 (Pubitemid 38461482)
26. Tauchi-Sato K, Ozeki S, Houjou T, Taguchi R, Fujimoto T (2002) The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition. J Biol Chem 277:44507-44512 (Pubitemid 36157885)
27. Tessitore L, Marengo B, Vance DE et al (2003) Expression of phosphatidylethnolamine N-methyItransferase in human hepatoceller carcinomas. Oncology 65(2):152-158 (Pubitemid 37025977)
28. Wang L, Liu C, Jia D, Zou W (2006) Separation and purification of phosphatidylcholine in swine liver and its inhibition effect on proliferation of rat hepatoma cells. Chin J Chromatogr 24:271-274
29. Wen-sheng W (2006) Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2. Cancer Lett 239:27-35 (Pubitemid 43946586)
30. Williams TM, Lisanti MP (2005) Caveolin-1 in oncogenic transformation, cancer, and metastasis. Am J Physiol Cell Physiol 288:494-506 (Pubitemid 40229478)
31. Yu Z, Zhang Y, Jia D, Zou W (2008a) The protective effects of hepatic-derived phospholipids on alcohol induced hepatic injury. Acta Nutrimenta Sinica 30:313-315
32. Yu Z, Zhang Y, Jia D, Cui Y, Zou W (2008b) The protective effects of phosphatidylcholine on hepatic cells injury induced by ethanol in vitro. Chin Hepatol 5:398-400
33. Zhou Z, Sun X, James Kang Y (2002) Metallothionein protection against alcoholic liver injury through inhibition of oxidative stress. Exp Biol Med 227:214-222
34. Zou W, Li ZY, Li YL et al (2002) Overexpression of PEMT2 downregulates the PI3 K/Akt signaling pathway in rat hepatoma cells. Biochim Biophys Acta 1581:49-56 (Pubitemid 34312047)