The relationship between malnutrition and immune function in the elderly;Malnutrition und Infekte

Therapeutische Umschau

Volumn 71, Issue 1, 2014, Pages 55-61

  Iliakis, Dimitrios ^a   Kressig, Reto W ^a  

^a Felix Platter Spital   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2;

AGING; ANTIBODY RESPONSE; CELLULAR IMMUNITY; DELAYED HYPERSENSITIVITY; DISEASE ASSOCIATION; HOST; IMMUNE DEFICIENCY; INFECTION; INFLAMMATION; MALNUTRITION; MORBIDITY; MORTALITY; NUTRITIONAL STATUS; REVIEW; TH1 CELL; TH2 CELL;

CYTOKINES; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGIC FACTORS; IMMUNOMODULATION; MALNUTRITION; MODELS, IMMUNOLOGICAL;

EID: 84891879893     PISSN: 00405930     EISSN: None     Source Type: Journal    
DOI: 10.1024/0040-5930/a000481     Document Type: Review

References (34)

1. Immoberdorf R, Rühlin M, Beerli A, Ballmer PE. Mangelernährung-Unterernährung. Schweiz Med Forum 2011; 11: 782-786.
2. De Groot CP, van Staveren WA. Undernutrition in the Euopean SENECA studies. Clin Geriatr Med 2002; 18: 699-708.
3. Bauer JM, Volkert D, Wirth R et al. Diagnostik der Mangelernährung des älteren Menschen. Dtsch Med Wochenschr 2006; 131: 223-7.
4. Nordenram G, Ljunggren G, Cederholm T. Nutritional status and chewing capacity in nursing home residents. Aging 2001; 13: 370-7.
5. Elia M, Ritz P, Stubbs RJ. Total Energy expenditure in the elderly. Eur J Clic Nutr 2000; 54: S92-103.
6. Drescher T, Singler K, Ulrich A et al. Comparison of two malnutrition risk screening methods (MNA and NRS 2002) and their association with markers of protein malnutrition in geriatric hospitalized patients. Eur J Clin Nutr 2010; 64: 887-93.
7. Kondrup J, Rasmussen HH, Hamberg O et al. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr 2003; 22: 321-336.
8. Immoberdorf R, Stanga Z, Ballmer PE. Mangelernährung: Auswirkungen bei akuter Erkrankung. Schweiz Med Forum 2001; 1: 892-5.
9. Chioléro R, Revelly JP, Tappy L. Energy metabolism in sepsis and injury. Nutrition 1997; 13 (9 Suppl): 45S-51S.
10. Chandra RK. Nutrition, immunity and infection: from basic knowledge of dietary manipulation of immune responses to practical application of ameliorating suffering and improving survival. Proc Natl Acad Sci USA 1996; 93: 14304-07.
11. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis 2002; 2: 659-66.
12. Wintergerst ES, Maggini S, Hornig DH. Contribution of Selected Vitamins and Trace Elements to Immune Function. Ann Nutr Metab 2007; 51: 301-323.
13. Parkin J, Cohen B. An overview of the immune system. Lancet 2001; 357: 1777-89.
14. Castle S. Clinical relevance of agerelated immune dysfunction. Clin Infect Dis 2000; 31: 578-585.
15. Hazeldine J, Lord JM. The impact of ageing on natural killer cell function and potential consequences for health in older adults. Ageing Res Rev 2013; S1568-1637: 00022-6. [Epub ahead of print].
16. Lesourd BM, Mazari L, Ferry M. The role of Nutrition in immunity in the aged. Nutr Rev 1998; 56: S113-25.
17. Lesourd BM, Mazari L. Immune responses during recovery from protein-energy malnutrition. Clin Nutr 1997; 16 Suppl 1: 37-46.
18. Delano MJ, Moldawer LL. The origins of cachexia in acute and chronic inflammatory syndrome. Am J Hosp Palliat Care 2008; 25: 407-411.
19. Jeejeebhoy KN. Malnutrition, fatigue, frailty, vulnerability, sarcopenia and cachexia: overlap of clinical features. Curr Opin Clin Nutr Metab Care 2012; 15: 213-9.
20. Mazari L, Lesourd BM. Nutritional influences on immune response in healthy aged persons. Mech Ageing Dev 1998; 104: 25-40.
21. Ahluwalia N, Mastro AM, Ball R, Miles MP, Rajendra R, Handte G. Cytokine production by stimulated mononuclear cells did not change with aging in apparently healthy, well-nourished women. Mech Ageing Dev 2001; 122: 1269-79.
22. Lesourd B, Mazari L. Nutrition and immunity in the elderly. Proc Nutr Soc 1999; 58: 685-95.
23. Cederholm T, Jägrén C, Hellström K. Outcome of protein-energy malnutrition in elderly medical patients. Am J Med 1995; 98: 67-74.
24. Sullivan DH, Walls RC, Bopp MM. Protein-energy undernutrition and the risk of mortality within one year of hospital discharge: a followup study. J Am Geriatr Soc 1995; 43: 507-12.
25. Lesourd B. Protein undernutrition as the major cause of decreased immune function in the elderly: clinical and functional implications. Nutr Rev 1995; 53 (4 Pt 2): S86-91; discussion S92-4.
26. Chandra RK, Kumari S. Nutrition and immunity: an overview. J Nutr 1994; 124 (8 Suppl): 1433S-1435S.
27. Lesourd BM. Immunologic aging. Effect of denutrition. Ann Biol Clin (Paris) 1990; 48: 309-18.
28. Moulias R, Devillechabrolle A, Lesourd B et al. Respective roles of immune and nutritional factors in the priming of the immune response in the elderly. Mech Ageing Dev 1985; 31: 123-37.
29. Klasing KC. Nutritional aspects of leukocytic cytokines. J Nutr 1988; 118: 1436-46.
30. de la Fuente M, Muñoz ML. Impairment of phagocytic process in macrophages from young and old mice by protein malnutrition. Ann Nutr Metab 1992; 36: 41-7.
31. Meydani SN, Meydani M, Blumberg JB et al. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial. JAMA 1997; 277: 1380-6.
32. Troen AM, Mitchell B, Sorensen B et al. Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr 2006; 136: 189-94.
33. Walker EM, Walker SM. Effects of iron overload on the immune system. Ann Clin Lab Sci 2000; 30: 354-365.
34. Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr 2007; 98 Suppl 1: S29-35.