메뉴 건너뛰기




Volumn 80, Issue 2, 2014, Pages 159-168

Molecular markers and targeted therapies for adrenocortical carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BEVACIZUMAB; CAPECITABINE; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FIBROBLAST GROWTH FACTOR; FIGITUMUMAB; GEFITINIB; GEMCITABINE; IMATINIB; LINSITINIB; MELANOCORTIN 2 RECEPTOR; MICRORNA; MOLECULAR MARKER; NVP AEW 541; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN B; STEROIDOGENIC FACTOR 1; THALIDOMIDE; VASCULOTROPIN;

EID: 84891872068     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12358     Document Type: Review
Times cited : (11)

References (112)
  • 1
    • 66749185880 scopus 로고    scopus 로고
    • Clinical review: Prevalence and incidence of endocrine and metabolic disorders in the United States: A comprehensive review
    • Golden, S.H., Robinson, K.A., Saldanha, I., et al,. (2009) Clinical review: prevalence and incidence of endocrine and metabolic disorders in the United States: a comprehensive review. Journal of Clinical Endocrinology and Metabolism, 94, 1853-1878.
    • (2009) Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 1853-1878
    • Golden, S.H.1    Robinson, K.A.2    Saldanha, I.3
  • 2
    • 33646593777 scopus 로고    scopus 로고
    • Extent of disease at presentation and outcome for adrenocortical carcinoma: Have we made progress?
    • DOI 10.1007/s00268-005-0329-x
    • Kebebew, E., Reiff, E., Duh, Q.Y., et al,. (2006) Extent of disease at presentation and outcome for adrenocortical carcinoma: have we made progress? World Journal of Surgery, 30, 872-878. (Pubitemid 43724119)
    • (2006) World Journal of Surgery , vol.30 , Issue.5 , pp. 872-878
    • Kebebew, E.1    Reiff, E.2    Duh, Q.-Y.3    Clark, O.H.4    McMillan, A.5
  • 4
    • 84862727987 scopus 로고    scopus 로고
    • The molecular basis of adrenocortical cancer
    • Lehmann, T., &, Wrzesinski, T., (2012) The molecular basis of adrenocortical cancer. Cancer Genetics, 205, 131-137.
    • (2012) Cancer Genetics , vol.205 , pp. 131-137
    • Lehmann, T.1    Wrzesinski, T.2
  • 7
    • 18844441782 scopus 로고    scopus 로고
    • Founder effect for the highly prevalent R337H mutation of tumor suppressor p53 in Brazilian patients with adrenocortical tumors
    • Pinto, E.M., Billerbeck, A.E., Villares, M.C., et al,. (2004) Founder effect for the highly prevalent R337H mutation of tumor suppressor p53 in Brazilian patients with adrenocortical tumors. Arquivos Brasileiros De Endocrinologia E Metabologia 48, 647-650.
    • (2004) Arquivos Brasileiros de Endocrinologia e Metabologia , vol.48 , pp. 647-650
    • Pinto, E.M.1    Billerbeck, A.E.2    Villares, M.C.3
  • 8
    • 84864328873 scopus 로고    scopus 로고
    • Expression profile of apoptosis-related genes in childhood adrenocortical tumors: Low level of expression of BCL2 and TNF genes suggests a poor prognosis
    • Lorea, C.F., Moreno, D.A., Borges, K.S., et al,. (2012) Expression profile of apoptosis-related genes in childhood adrenocortical tumors: low level of expression of BCL2 and TNF genes suggests a poor prognosis. European Journal of Endocrinology, 167, 199-208.
    • (2012) European Journal of Endocrinology , vol.167 , pp. 199-208
    • Lorea, C.F.1    Moreno, D.A.2    Borges, K.S.3
  • 11
    • 80053312970 scopus 로고    scopus 로고
    • Contemporary management of adrenocortical carcinoma
    • Zini, L., Porpiglia, F., &, Fassnacht, M., (2011) Contemporary management of adrenocortical carcinoma. European Urology, 60, 1055-1065.
    • (2011) European Urology , vol.60 , pp. 1055-1065
    • Zini, L.1    Porpiglia, F.2    Fassnacht, M.3
  • 16
    • 33744952176 scopus 로고    scopus 로고
    • Clinical review: Adrenocortical carcinoma: Clinical update
    • DOI 10.1210/jc.2005-2639
    • Allolio, B., &, Fassnacht, M., (2006) Clinical review: adrenocortical carcinoma: clinical update. Journal of Clinical Endocrinology and Metabolism, 91, 2027-2037. (Pubitemid 43854976)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.6 , pp. 2027-2037
    • Allolio, B.1    Fassnacht, M.2
  • 18
    • 77957262044 scopus 로고    scopus 로고
    • Adjuvant therapy in patients with adrenocortical carcinoma: A position of an international panel
    • author reply e403
    • Berruti, A., Fassnacht, M., Baudin, E., et al,. (2010) Adjuvant therapy in patients with adrenocortical carcinoma: a position of an international panel. Journal of Clinical Oncology, 28, e401-e402; author reply e403.
    • (2010) Journal of Clinical Oncology , vol.28
    • Berruti, A.1    Fassnacht, M.2    Baudin, E.3
  • 20
    • 45749105609 scopus 로고    scopus 로고
    • Molecular markers and the pathogenesis of adrenocortical cancer
    • DOI 10.1634/theoncologist.2007-0243
    • Soon, P.S., McDonald, K.L., Robinson, B.G., et al,. (2008) Molecular markers and the pathogenesis of adrenocortical cancer. Oncologist, 13, 548-561. (Pubitemid 351872872)
    • (2008) Oncologist , vol.13 , Issue.5 , pp. 548-561
    • Soon, P.S.H.1    McDonald, K.L.2    Robinson, B.G.3    Sidhu, S.B.4
  • 21
    • 84887235975 scopus 로고    scopus 로고
    • Adrenocortical carcinoma is a lynch syndrome-associated cancer
    • Raymond, V.M., Everett, J.N., Furtado, L.V., et al,. (2013) Adrenocortical carcinoma is a lynch syndrome-associated cancer. Journal of Clinical Oncology, 31, 3012-3018.
    • (2013) Journal of Clinical Oncology , vol.31 , pp. 3012-3018
    • Raymond, V.M.1    Everett, J.N.2    Furtado, L.V.3
  • 23
    • 61449137784 scopus 로고    scopus 로고
    • Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival
    • de Reynies, A., Assie, G., Rickman, D.S., et al,. (2009) Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival. Journal of Clinical Oncology, 27, 1108-1115.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 1108-1115
    • De Reynies, A.1    Assie, G.2    Rickman, D.S.3
  • 24
    • 37549045051 scopus 로고    scopus 로고
    • Loss of heterozygosity of 17p13, with possible involvement of ACADVL and ALOX15B, in the pathogenesis of adrenocortical tumors
    • Soon, P.S., Libe, R., Benn, D.E., et al,. (2008) Loss of heterozygosity of 17p13, with possible involvement of ACADVL and ALOX15B, in the pathogenesis of adrenocortical tumors. Annals of Surgery, 247, 157-164.
    • (2008) Annals of Surgery , vol.247 , pp. 157-164
    • Soon, P.S.1    Libe, R.2    Benn, D.E.3
  • 28
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: News from the mutant p53 field
    • Brosh, R., &, Rotter, V., (2009) When mutants gain new powers: news from the mutant p53 field. Nature Reviews Cancer, 9, 701-713.
    • (2009) Nature Reviews Cancer , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, V.2
  • 29
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein, B., Lane, D., &, Levine, A.J., (2000) Surfing the p53 network. Nature, 408, 307-310.
    • (2000) Nature , vol.408 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 33
    • 0028177520 scopus 로고
    • P53 mutations in human adrenocortical neoplasms: Immunohistochemical and molecular studies
    • Reincke, M., Karl, M., Travis, W.H., et al,. (1994) p53 mutations in human adrenocortical neoplasms: immunohistochemical and molecular studies. Journal of Clinical Endocrinology and Metabolism, 78, 790-794.
    • (1994) Journal of Clinical Endocrinology and Metabolism , vol.78 , pp. 790-794
    • Reincke, M.1    Karl, M.2    Travis, W.H.3
  • 36
    • 78449270065 scopus 로고    scopus 로고
    • Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers
    • Ragazzon, B., Libe, R., Gaujoux, S., et al,. (2010) Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers. Cancer Research, 70, 8276-8281.
    • (2010) Cancer Research , vol.70 , pp. 8276-8281
    • Ragazzon, B.1    Libe, R.2    Gaujoux, S.3
  • 40
    • 18844379914 scopus 로고    scopus 로고
    • Deletion mapping of chromosome 17 in benign and malignant adrenocortical tumors associated with the Arg337His mutation of the p53 tumor suppressor protein
    • DOI 10.1210/jc.2004-0963
    • Pinto, E.M., Billerbeck, A.E., Fragoso, M.C., et al,. (2005) Deletion mapping of chromosome 17 in benign and malignant adrenocortical tumors associated with the Arg337His mutation of the p53 tumor suppressor protein. Journal of Clinical Endocrinology and Metabolism, 90, 2976-2981. (Pubitemid 40686352)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.5 , pp. 2976-2981
    • Pinto, E.M.1    Billerbeck, A.E.C.2    Fragoso, M.C.B.V.3    Mendonca, B.B.4    Latronico, A.C.5
  • 42
    • 0033975096 scopus 로고    scopus 로고
    • Beckwith-Wiedemann syndrome: Imprinting in clusters revisited
    • Maher, E.R., &, Reik, W., (2000) Beckwith-Wiedemann syndrome: imprinting in clusters revisited. Journal of Clinical Investigation, 105, 247-252. (Pubitemid 30094443)
    • (2000) Journal of Clinical Investigation , vol.105 , Issue.3 , pp. 247-252
    • Maher, E.R.1    Reik, W.2
  • 46
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: Overview and recent insights
    • DOI 10.1210/er.2006-0001
    • Samani, A.A., Yakar, S., LeRoith, D., et al,. (2007) The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocrine Reviews, 28, 20-47. (Pubitemid 46220849)
    • (2007) Endocrine Reviews , vol.28 , Issue.1 , pp. 20-47
    • Samani, A.A.1    Yakar, S.2    LeRoith, D.3    Brodt, P.4
  • 47
    • 0031784613 scopus 로고    scopus 로고
    • Increased levels of insulin-like growth factor II (IGF-II) and IGF- binding protein-2 are associated with malignancy in sporadic adrenocortical tumors
    • DOI 10.1210/jc.83.5.1713
    • Boulle, N., Logie, A., Gicquel, C., et al,. (1998) Increased levels of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 are associated with malignancy in sporadic adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism, 83, 1713-1720. (Pubitemid 28501047)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.5 , pp. 1713-1720
    • Boulle, N.1    Logie, A.2    Gicquel, C.3    Perin, L.4    Bouc, Y.L.5
  • 49
    • 0030996260 scopus 로고    scopus 로고
    • Insulin-like growth factor receptors in normal and tumorous adult human adrenocortical glands
    • Weber, M.M., Auernhammer, C.J., Kiess, W., et al,. (1997) Insulin-like growth factor receptors in normal and tumorous adult human adrenocortical glands. European Journal of Endocrinology, 136, 296-303. (Pubitemid 27130054)
    • (1997) European Journal of Endocrinology , vol.136 , Issue.3 , pp. 296-303
    • Weber, M.M.1    Auernhammer, C.J.2    Kiess, W.3    Engelhardt, D.4
  • 50
    • 77953168294 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors
    • Doghman, M., El Wakil, A., Cardinaud, B., et al,. (2010) Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors. Cancer Research, 70, 4666-4675.
    • (2010) Cancer Research , vol.70 , pp. 4666-4675
    • Doghman, M.1    El Wakil, A.2    Cardinaud, B.3
  • 51
    • 51649083560 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors
    • Almeida, M.Q., Fragoso, M.C., Lotfi, C.F., et al,. (2008) Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism, 93, 3524-3531.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 3524-3531
    • Almeida, M.Q.1    Fragoso, M.C.2    Lotfi, C.F.3
  • 52
    • 58149381997 scopus 로고    scopus 로고
    • Preclinical targeting of the type i insulin-like growth factor receptor in adrenocortical carcinoma
    • Barlaskar, F.M., Spalding, A.C., Heaton, J.H., et al,. (2009) Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma. Journal of Clinical Endocrinology and Metabolism, 94, 204-212.
    • (2009) Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 204-212
    • Barlaskar, F.M.1    Spalding, A.C.2    Heaton, J.H.3
  • 54
    • 75749102231 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma
    • Haluska, P., Worden, F., Olmos, D., et al,. (2010) Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma. Cancer Chemotherapy and Pharmacology, 65, 765-773.
    • (2010) Cancer Chemotherapy and Pharmacology , vol.65 , pp. 765-773
    • Haluska, P.1    Worden, F.2    Olmos, D.3
  • 55
    • 68849086676 scopus 로고    scopus 로고
    • Preliminary activity in adrenocortical tumor (ACC) in phase i dose escalation study of intermittent oral dosing of OSI-906, a small-molecule insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase inhibitor in patients with advanced solid tumors
    • Carden, C.P., Frentzas, S., Langham, M., et al,. (2009) Preliminary activity in adrenocortical tumor (ACC) in phase I dose escalation study of intermittent oral dosing of OSI-906, a small-molecule insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase inhibitor in patients with advanced solid tumors. Journal of Clinical Oncology, 27.
    • (2009) Journal of Clinical Oncology , vol.27
    • Carden, C.P.1    Frentzas, S.2    Langham, M.3
  • 56
    • 50649101532 scopus 로고    scopus 로고
    • Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex
    • Kim, A.C., Reuter, A.L., Zubair, M., et al,. (2008) Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development, 135, 2593-2602.
    • (2008) Development , vol.135 , pp. 2593-2602
    • Kim, A.C.1    Reuter, A.L.2    Zubair, M.3
  • 58
    • 78650520052 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway in adrenocortical development and cancer
    • El Wakil, A., &, Lalli, E., (2011) The Wnt/beta-catenin pathway in adrenocortical development and cancer. Molecular and Cellular Endocrinology, 332, 32-37.
    • (2011) Molecular and Cellular Endocrinology , vol.332 , pp. 32-37
    • El Wakil, A.1    Lalli, E.2
  • 59
    • 53749096474 scopus 로고    scopus 로고
    • Wnt/beta-catenin and 3′,5′-cyclic adenosine 5′-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors
    • Gaujoux, S., Tissier, F., Groussin, L., et al,. (2008) Wnt/beta-catenin and 3′,5′-cyclic adenosine 5′-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism, 93, 4135-4140.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 4135-4140
    • Gaujoux, S.1    Tissier, F.2    Groussin, L.3
  • 60
    • 38049130282 scopus 로고    scopus 로고
    • Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas
    • Tadjine, M., Lampron, A., Ouadi, L., et al,. (2008) Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas. Clinical Endocrinology, 68, 264-270.
    • (2008) Clinical Endocrinology , vol.68 , pp. 264-270
    • Tadjine, M.1    Lampron, A.2    Ouadi, L.3
  • 62
    • 77952300541 scopus 로고    scopus 로고
    • Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development
    • Berthon, A., Sahut-Barnola, I., Lambert-Langlais, S., et al,. (2010) Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development. Human Molecular Genetics, 19, 1561-1576.
    • (2010) Human Molecular Genetics , vol.19 , pp. 1561-1576
    • Berthon, A.1    Sahut-Barnola, I.2    Lambert-Langlais, S.3
  • 64
    • 49249137734 scopus 로고    scopus 로고
    • The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells
    • Doghman, M., Cazareth, J., &, Lalli, E., (2008) The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells. Journal of Clinical Endocrinology and Metabolism, 93, 3222-3225.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 3222-3225
    • Doghman, M.1    Cazareth, J.2    Lalli, E.3
  • 65
    • 77954832944 scopus 로고    scopus 로고
    • Minireview: Steroidogenic factor 1: Its roles in differentiation, development, and disease
    • Schimmer, B.P., &, White, P.C., (2010) Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease. Molecular Endocrinology, 24, 1322-1337.
    • (2010) Molecular Endocrinology , vol.24 , pp. 1322-1337
    • Schimmer, B.P.1    White, P.C.2
  • 66
    • 77952773441 scopus 로고    scopus 로고
    • Adrenocortical development and cancer: Focus on SF-1
    • Lalli, E., (2010) Adrenocortical development and cancer: focus on SF-1. Journal of Molecular Endocrinology, 44, 301-307.
    • (2010) Journal of Molecular Endocrinology , vol.44 , pp. 301-307
    • Lalli, E.1
  • 69
    • 77749233736 scopus 로고    scopus 로고
    • Steroidogenic factor 1 overexpression and gene amplification are more frequent in adrenocortical tumors from children than from adults
    • Almeida, M.Q., Soares, I.C., Ribeiro, T.C., et al,. (2010) Steroidogenic factor 1 overexpression and gene amplification are more frequent in adrenocortical tumors from children than from adults. Journal of Clinical Endocrinology and Metabolism, 95, 1458-1462.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , pp. 1458-1462
    • Almeida, M.Q.1    Soares, I.C.2    Ribeiro, T.C.3
  • 72
    • 77957771843 scopus 로고    scopus 로고
    • High diagnostic and prognostic value of steroidogenic factor-1 expression in adrenal tumors
    • Sbiera, S., Schmull, S., Assie, G., et al,. (2010) High diagnostic and prognostic value of steroidogenic factor-1 expression in adrenal tumors. Journal of Clinical Endocrinology and Metabolism, 95, E161-E171.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95
    • Sbiera, S.1    Schmull, S.2    Assie, G.3
  • 73
    • 66749179396 scopus 로고    scopus 로고
    • Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists
    • Doghman, M., Cazareth, J., Douguet, D., et al,. (2009) Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists. Journal of Clinical Endocrinology and Metabolism, 94, 2178-2183.
    • (2009) Journal of Clinical Endocrinology and Metabolism , vol.94 , pp. 2178-2183
    • Doghman, M.1    Cazareth, J.2    Douguet, D.3
  • 74
    • 0021604062 scopus 로고
    • Control of adrenocortical growth in vivo
    • Dallman, M.F., (1984) Control of adrenocortical growth in vivo. Endocrine Research, 10, 213-242. (Pubitemid 15018384)
    • (1984) Endocrine Research , vol.10 , Issue.3-4 , pp. 213-242
    • Dallman, M.F.1
  • 78
    • 84881557332 scopus 로고    scopus 로고
    • Expression of Wnt and TGF-beta pathway components and key adrenal transcription factors in adrenocortical tumors: Association to carcinoma aggressiveness
    • Parviainen, H., Schrade, A., Kiiveri, S., et al,. (2013) Expression of Wnt and TGF-beta pathway components and key adrenal transcription factors in adrenocortical tumors: association to carcinoma aggressiveness. Pathology, Research and Practice, 209, 503-509.
    • (2013) Pathology, Research and Practice , vol.209 , pp. 503-509
    • Parviainen, H.1    Schrade, A.2    Kiiveri, S.3
  • 79
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • DOI 10.1056/NEJMra0706596
    • Kerbel, R.S., (2008) Tumor angiogenesis. New England Journal of Medicine, 358, 2039-2049. (Pubitemid 351656458)
    • (2008) New England Journal of Medicine , vol.358 , Issue.19 , pp. 2039-2049
    • Kerbel, R.S.1
  • 80
    • 0035704913 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor in angiogenesis
    • DOI 10.1159/000046610
    • Ferrara, N., &, Gerber, H.P., (2001) The role of vascular endothelial growth factor in angiogenesis. Acta Haematologica, 106, 148-156. (Pubitemid 34124153)
    • (2001) Acta Haematologica , vol.106 , Issue.4 , pp. 148-156
    • Ferrara, N.1    Gerber, H.-P.2
  • 82
    • 0034489211 scopus 로고    scopus 로고
    • Expression of the angiogenesis markers vascular endothelial growth factor-A, thrombospondin-1, and platelet-derived endothelial cell growth factor in human sporadic adrenocortical tumors: Correlation with genotypic alterations
    • DOI 10.1210/jc.85.12.4734
    • de Fraipont, F., El Atifi, M., Gicquel, C., et al,. (2000) Expression of the angiogenesis markers vascular endothelial growth factor-A, thrombospondin-1, and platelet-derived endothelial cell growth factor in human sporadic adrenocortical tumors: correlation with genotypic alterations. Journal of Clinical Endocrinology and Metabolism, 85, 4734-4741. (Pubitemid 32157660)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.12 , pp. 4734-4741
    • De Fraipont, F.1    El Atifi, M.2    Gicquel, C.3    Bertagna, X.4    Chambaz, E.M.5    Feige, J.J.6
  • 83
    • 0033629896 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor evaluation in blood serum of patients with hormonally active and inactive adrenal gland tumours
    • Kolomecki, K., Stepien, H., &, Narebski, J.M., (2000) Vascular endothelial growth factor and basic fibroblast growth factor evaluation in blood serum of patients with hormonally active and inactive adrenal gland tumours. Cytobios, 101, 55-64.
    • (2000) Cytobios , vol.101 , pp. 55-64
    • Kolomecki, K.1    Stepien, H.2    Narebski, J.M.3
  • 84
    • 0035287650 scopus 로고    scopus 로고
    • Usefulness of VEGF, MMP-2, MMP-3 and TIMP-2 serum level evaluation in patients with adrenal tumours
    • Kolomecki, K., Stepien, H., Bartos, M., et al,. (2001) Usefulness of VEGF, MMP-2, MMP-3 and TIMP-2 serum level evaluation in patients with adrenal tumours. Endocrine Regulations, 35, 9-16. (Pubitemid 33711948)
    • (2001) Endocrine Regulations , vol.35 , Issue.1 , pp. 9-16
    • Kolomecki, K.1    Stepien, H.2    Bartos, M.3    Kuzdak, K.4
  • 85
    • 84858758545 scopus 로고    scopus 로고
    • Significance of heparanase-1 and vascular endothelial growth factor in adrenocortical carcinoma angiogenesis: Potential for therapy
    • Xu, Y.Z., Zhu, Y., Shen, Z.J., et al,. (2011) Significance of heparanase-1 and vascular endothelial growth factor in adrenocortical carcinoma angiogenesis: potential for therapy. Endocrine, 40, 445-451.
    • (2011) Endocrine , vol.40 , pp. 445-451
    • Xu, Y.Z.1    Zhu, Y.2    Shen, Z.J.3
  • 87
    • 75149143015 scopus 로고    scopus 로고
    • Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma
    • Wortmann, S., Quinkler, M., Ritter, C., et al,. (2010) Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma. European Journal of Endocrinology, 162, 349-356.
    • (2010) European Journal of Endocrinology , vol.162 , pp. 349-356
    • Wortmann, S.1    Quinkler, M.2    Ritter, C.3
  • 88
    • 0025193837 scopus 로고
    • Immunohistochemial expression of epidermal growth factor receptors in human adrenocortical carcinoma
    • DOI 10.1016/0046-8177(90)90227-V
    • Kamio, T., Shigematsu, K., Sou, H., et al,. (1990) Immunohistochemical expression of epidermal growth factor receptors in human adrenocortical carcinoma. Human Pathology, 21, 277-282. (Pubitemid 20081227)
    • (1990) Human Pathology , vol.21 , Issue.3 , pp. 277-282
    • Kamio, T.1    Shigematsu, K.2    Sou, H.3    Kawai, K.4    Tsuchiyama, H.5
  • 89
    • 66349120812 scopus 로고    scopus 로고
    • An analysis of potential surrogate markers of target-specific therapy in archival materials of adrenocortical carcinoma
    • Nakamura, M., Miki, Y., Akahira, J., et al,. (2009) An analysis of potential surrogate markers of target-specific therapy in archival materials of adrenocortical carcinoma. Endocrine Pathology, 20, 17-23.
    • (2009) Endocrine Pathology , vol.20 , pp. 17-23
    • Nakamura, M.1    Miki, Y.2    Akahira, J.3
  • 90
    • 78649705561 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in adrenocortical tumors: Analysis of gene sequence, protein expression and correlation with clinical outcome
    • Adam, P., Hahner, S., Hartmann, M., et al,. (2010) Epidermal growth factor receptor in adrenocortical tumors: analysis of gene sequence, protein expression and correlation with clinical outcome. Modern Pathology, 23, 1596-1604.
    • (2010) Modern Pathology , vol.23 , pp. 1596-1604
    • Adam, P.1    Hahner, S.2    Hartmann, M.3
  • 93
    • 58249101005 scopus 로고    scopus 로고
    • The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors
    • Huang, F., Greer, A., Hurlburt, W., et al,. (2009) The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors. Cancer Research, 69, 161-170.
    • (2009) Cancer Research , vol.69 , pp. 161-170
    • Huang, F.1    Greer, A.2    Hurlburt, W.3
  • 95
    • 34548845901 scopus 로고    scopus 로고
    • Precursor lesions of the adrenal gland
    • DOI 10.1159/000105811
    • van Nederveen, F.H., &, de Krijger, R.R., (2007) Precursor lesions of the adrenal gland. Pathobiology, 74, 285-290. (Pubitemid 47450574)
    • (2007) Pathobiology , vol.74 , Issue.5 , pp. 285-290
    • Van Nederveen, F.H.1    De Krijger, R.R.2
  • 96
    • 14944378110 scopus 로고    scopus 로고
    • CASE 2. Response in a patient with metastatic adrenal cortical carcinoma with thalidomide
    • Chacon, R., Tossen, G., Loria, F.S., et al,. (2005) CASE 2. Response in a patient with metastatic adrenal cortical carcinoma with thalidomide. Journal of Clinical Oncology, 23, 1579-1580.
    • (2005) Journal of Clinical Oncology , vol.23 , pp. 1579-1580
    • Chacon, R.1    Tossen, G.2    Loria, F.S.3
  • 97
  • 98
    • 79953767181 scopus 로고    scopus 로고
    • MicroRNA profiling of adrenocortical tumors reveals miR-483 as a marker of malignancy
    • Patterson, E.E., Holloway, A.K., Weng, J., et al,. (2011) MicroRNA profiling of adrenocortical tumors reveals miR-483 as a marker of malignancy. Cancer, 117, 1630-1639.
    • (2011) Cancer , vol.117 , pp. 1630-1639
    • Patterson, E.E.1    Holloway, A.K.2    Weng, J.3
  • 99
    • 79956291547 scopus 로고    scopus 로고
    • Differential expression of microRNA-675, microRNA-139-3p and microRNA-335 in benign and malignant adrenocortical tumours
    • Schmitz, K.J., Helwig, J., Bertram, S., et al,. (2011) Differential expression of microRNA-675, microRNA-139-3p and microRNA-335 in benign and malignant adrenocortical tumours. Journal of Clinical Pathology, 64, 529-535.
    • (2011) Journal of Clinical Pathology , vol.64 , pp. 529-535
    • Schmitz, K.J.1    Helwig, J.2    Bertram, S.3
  • 100
    • 72749126286 scopus 로고    scopus 로고
    • Integrative molecular bioinformatics study of human adrenocortical tumors: MicroRNA, tissue-specific target prediction, and pathway analysis
    • Tombol, Z., Szabo, P.M., Molnar, V., et al,. (2009) Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis. Endocrine-Related Cancer, 16, 895-906.
    • (2009) Endocrine-Related Cancer , vol.16 , pp. 895-906
    • Tombol, Z.1    Szabo, P.M.2    Molnar, V.3
  • 101
    • 46249083024 scopus 로고    scopus 로고
    • MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations
    • DOI 10.1002/hep.22256
    • Ladeiro, Y., Couchy, G., Balabaud, C., et al,. (2008) MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology, 47, 1955-1963. (Pubitemid 351952843)
    • (2008) Hepatology , vol.47 , Issue.6 , pp. 1955-1963
    • Ladeiro, Y.1    Couchy, G.2    Balabaud, C.3    Bioulac-Sage, P.4    Pelletier, L.5    Rebouissou, S.6    Zucman-Rossi, J.7
  • 102
    • 73349137922 scopus 로고    scopus 로고
    • MiR-195 and miR-483-5p identified as predictors of poor prognosis in adrenocortical cancer
    • Soon, P.S., Tacon, L.J., Gill, A.J., et al,. (2009) miR-195 and miR-483-5p identified as predictors of poor prognosis in adrenocortical cancer. Clinical Cancer Research, 15, 7684-7692.
    • (2009) Clinical Cancer Research , vol.15 , pp. 7684-7692
    • Soon, P.S.1    Tacon, L.J.2    Gill, A.J.3
  • 103
    • 67650480396 scopus 로고    scopus 로고
    • Microarray gene expression and immunohistochemistry analyses of adrenocortical tumors identify IGF2 and Ki-67 as useful in differentiating carcinomas from adenomas
    • Soon, P.S., Gill, A.J., Benn, D.E., et al,. (2009) Microarray gene expression and immunohistochemistry analyses of adrenocortical tumors identify IGF2 and Ki-67 as useful in differentiating carcinomas from adenomas. Endocrine-Related Cancer, 16, 573-583.
    • (2009) Endocrine-Related Cancer , vol.16 , pp. 573-583
    • Soon, P.S.1    Gill, A.J.2    Benn, D.E.3
  • 104
    • 84882802768 scopus 로고    scopus 로고
    • Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients
    • Chabre, O., Libe, R., Assie, G., et al,. (2013) Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. Endocrine-Related Cancer, 20, 579-594.
    • (2013) Endocrine-Related Cancer , vol.20 , pp. 579-594
    • Chabre, O.1    Libe, R.2    Assie, G.3
  • 105
    • 82755187564 scopus 로고    scopus 로고
    • Extracellular microRNA: A new source of biomarkers
    • Etheridge, A., Lee, I., Hood, L., et al,. (2011) Extracellular microRNA: a new source of biomarkers. Mutation Research, 717, 85-90.
    • (2011) Mutation Research , vol.717 , pp. 85-90
    • Etheridge, A.1    Lee, I.2    Hood, L.3
  • 108
    • 84861333951 scopus 로고    scopus 로고
    • DNA methylation profiling identifies global methylation differences and markers of adrenocortical tumors
    • Rechache, N.S., Wang, Y., Stevenson, H.S., et al,. (2012) DNA methylation profiling identifies global methylation differences and markers of adrenocortical tumors. Journal of Clinical Endocrinology and Metabolism, 97, E1004-E1013.
    • (2012) Journal of Clinical Endocrinology and Metabolism , vol.97
    • Rechache, N.S.1    Wang, Y.2    Stevenson, H.S.3
  • 109
    • 84864770512 scopus 로고    scopus 로고
    • Comprehensive DNA methylation analysis of benign and malignant adrenocortical tumors
    • Fonseca, A.L., Kugelberg, J., Starker, L.F., et al,. (2012) Comprehensive DNA methylation analysis of benign and malignant adrenocortical tumors. Genes Chromosomes Cancer, 51, 949-960.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 949-960
    • Fonseca, A.L.1    Kugelberg, J.2    Starker, L.F.3
  • 110
    • 75149143015 scopus 로고    scopus 로고
    • Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma
    • Wortmann, S., Quinkler, M., Ritter, C., et al,. (2010) Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma. European Journal of Endocrinology, 162, 349-356.
    • (2010) European Journal of Endocrinology , vol.162 , pp. 349-356
    • Wortmann, S.1    Quinkler, M.2    Ritter, C.3
  • 112
    • 65749083279 scopus 로고    scopus 로고
    • A phase II trial of gefitinib monotherapy in patients with unresectable adrenocortical carcinoma (ACC)
    • Samnotra, V., Vassilopoulou-Sellin, R., &, Fojo, A.T., (2007) A phase II trial of gefitinib monotherapy in patients with unresectable adrenocortical carcinoma (ACC). Journal of Clinical Oncology.
    • (2007) Journal of Clinical Oncology
    • Samnotra, V.1    Vassilopoulou-Sellin, R.2    Fojo, A.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.