Melanocortin 2 receptor is required for adrenal gland development, steroidogenesis, and neonatal gluconeogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 46, 2007, Pages 18205-18210

  Chida, Dai ^a,b   Nakagawa, Shinichi ^c   Nagai, So ^d   Sagara, Hiroshi ^a   Katsumata, Harumi ^e   Imaki, Toshihiro ^e   Suzuki, Harumi ^b   Mitani, Fumiko ^f   Ogishima, Tadashi ^g   Shimizu, Chikara ^d   Kotaki, Hayato ^a   Kakuta, Shigeru ^a   Sudo, Katsuko ^a,h   Koike, Takao ^d   Kubo, Mitsumasa ⁱ   Iwakura, Yoichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^c Japan Science and Technology Agency   (Japan)

^d HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e NIPPON MEDICAL SCHOOL   (Japan)

^f KEIO UNIVERSITY   (Japan)

^g KYUSHU UNIVERSITY   (Japan)

^h TOKYO MEDICAL UNIVERSITY   (Japan)

ⁱ HOKKAIDO UNIVERSITY OF EDUCATION   (Japan)

Author keywords

Adrenocorticotropic hormone (ACTH); Familial glucocorticoid deficiency (FGD); Hypothalamus pituitary adrenal; Zona fasciculata

Indexed keywords

CORTICOTROPIN; MELANOCORTIN 2 RECEPTOR;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; GENE FUNCTION; GENE INACTIVATION; GLUCONEOGENESIS; HYPOGLYCEMIA; KIDNEY MEDULLA; MOUSE; NONHUMAN; PERINATAL DEVELOPMENT; PHENOTYPE; PRIORITY JOURNAL; STEROIDOGENESIS; ZONA FASCICULATA; ZONA GLOMERULOSA;

ADRENAL GLANDS; ANIMALS; ANIMALS, NEWBORN; GLUCONEOGENESIS; MICE; MICE, KNOCKOUT; RECEPTOR, MELANOCORTIN, TYPE 2; STEROIDS;

ANIMALIA; MUS;

EID: 36749073453     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0706953104     Document Type: Article

References (31)

1. Dallman MF (1984) Endocr Res 10:213-242.
2. Yaswen L, Diehl N, Brennan MB, Hochgeschwender U (1999) Nat Med 5:1066-1070.
3. Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, et al. (2004) Proc Natl Acad Sci USA 101:4695-4700.
4. Coll AP, Challis BG, Yeo GS, Snell K, Piper SJ, Halsall D, Thresher RR, O'Rahilly S (2004) Endocrinology 145:4721-4727.
5. Smart JL, Tolle V, Otero-Corchon V, Low MJ (2007) Endocrinology 148:647-659.
6. Clark AJL, Weber A (1998) Endocr Rev 19:828-843.
7. Metherell LA, Chapple JP, Cooray S, David A, Becker C, Ruschendorf F, Naville D, Begeot M, Khoo B, Nurnberg P, et al. (2005) Nat Genet 37:166-170.
8. Genin E, Huebner A, Jaillard C, Faure A, Halaby G, Saka N, Clark AJ, Durand P, Begeot M, Naville D (2002) Hum Genet 111:428-434.
9. Shimizu C, Kubo M, Saeki T, Matsumura T, Ishizuka T, Kijima H, Kakinuma M, Koike T (1997) Gene 188:17-21.
10. Clark AJ, Cammas FM, Watt A, Kapas S, Weber A (1997) J Mol Med 75:394-399.
11. Coll AP, Challis BG, Lopez M, Piper S, Yeo GS, O'Rahilly S (2005) Diabetes 54:2269-2276.
12. Miller WL (1988) Endocr Rev 9:295-318.
13. Finotto S, Krieglstein K, Schober A, Deimling F, Lindner K, Bruhl B, Beier K, Metz J, Garcia-Arraras JE, Roig-Lopez JL, et al. (1999) Development (Cambridge, UK) 126:2935-2944.
14. Pilkis SJ, Granner DK (1992) Annu Rev Physiol 54:885-909.
15. Girard J, Ferre P, Pegorier JP, Duee PH (1992) Physiol Rev 72:507-562.
16. Wang ND, Finegold MJ, Bradley A, Ou CN, Abdelsayed SV, Wilde MD, Taylor LR, Wilson DR, Darlington GJ (1995) Science 269:1108-1112.
17. Tronche F, Opherk C, Moriggl R, Kellendonk C, Reimann A, Schwake L, Reichardt HM, Stangl K, Gau D, Hoeflich A, et al. (2004) Genes Dev 18:492-497.
18. Smart JL, Tolle V, Low MJ (2006) J Clin Invest 116:495-505.
19. Clark AJ, Metherell LA, Cheetham ME, Huebner A (2005) Trends Endocrinol Metab 16:451-457.
20. Hershkovitz L, Beuschlein F, Klammer S, Krup M, Weinstein Y (2007) Endocrinology 148:976-988.
21. Karpac J, Ostwald D, Bui S, Hunnewell P, Shankar M, Hochgeschwender U (2005) Endocrinology 146:2555-2562.
22. Estivariz FE, Iturriza F, McLean C, Hope J, Lowry PJ (1982) Nature 297:419-422.
23. Coll AP, Fassnacht M, Klammer S, Hahner S, Schulte DM, Piper S, Tung YC, Challis BG, Weinstein Y, Allolio B, et al. (2006) J Endocrinol 190:515-525.
24. Clark AJ, McLoughlin L, Grossman A (1993) Lancet 341:461-462.
25. Lin L, Hindmarsh PC, Metherell LA, Alzyoud M, Al-Ali M, Brain CE, Clark AJ, Dattani MT, Achermann JC (2007) Clin Endocrinol (Oxford) 66:205-210.
26. Cole TJ, Blendy JA, Monaghan AP, Krieglstein K, Schmid W, Aguzzi A, Fantuzzi G, Hummler E, Unsicker K, Schutz G (1995) Genes Dev 9:1608-1621.
27. Boston BA, Cone RD (1996) Endocrinology 137:2043-2050.
28. Genuth S, Lebovitz HE (1965) Endocrinology 76:1093-1099.
29. Arck PC, Slominski A, Theoharides TC, Peters EM, Paus R (2006) J Invest Dermatol 126:1697-1704.
30. Matsuki T, Isoda K, Horai R, Nakajima A, Aizawa Y, Suzuki K, Ohsuzu F, Iwakura Y (2005) Circulation 112:1323-1331.
31. Wang X, Seed B (December 15, 2003) Nucleic Acids Res 31, 10.1093/nar/gng154.