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Volumn 70, Issue 11, 2010, Pages 4666-4675

Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by MicroRNA in childhood adrenocortical tumors

Author keywords

[No Author keywords available]

Indexed keywords

EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MICRORNA 100; MICRORNA 99A; SERINE; SOMATOMEDIN; UNCLASSIFIED DRUG;

EID: 77953168294     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3970     Document Type: Article
Times cited : (187)

References (42)
  • 1
    • 34249810952 scopus 로고    scopus 로고
    • Adrenocortical cancer: Pathophysiology and clinical management
    • Libé R, Fratticci A, Bertherat J. Adrenocortical cancer: pathophysiology and clinical management. Endocr Relat Cancer 2007;14:13-28.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 13-28
    • Libé, R.1    Fratticci, A.2    Bertherat, J.3
  • 2
    • 1542713361 scopus 로고    scopus 로고
    • Clinical and outcome characteristics of children with adrenocortical tumors. An analysis of 254 cases from the International Pediatric Adrenocortical Tumor Registry
    • Michalkiewicz E, Sandrini R, Figueiredo B, et al. Clinical and outcome characteristics of children with adrenocortical tumors. An analysis of 254 cases from the International Pediatric Adrenocortical Tumor Registry. J Clin Oncol 2004;22:838-845
    • (2004) J Clin Oncol , vol.22 , pp. 838-845
    • Michalkiewicz, E.1    Sandrini, R.2    Figueiredo, B.3
  • 3
    • 0035979262 scopus 로고    scopus 로고
    • An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma
    • Ribeiro RC, Sandrini F, Figueiredo B, et al. An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma. Proc Natl Acad Sci U S A 2001;98:9330-9335
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9330-9335
    • Ribeiro, R.C.1    Sandrini, F.2    Figueiredo, B.3
  • 4
    • 0034457110 scopus 로고    scopus 로고
    • Pediatric adrenocortical tumors: Molecular events leading to insulin-like growth factor II gene overexpression
    • Wilkin F, Gagné N, Paquette J, Oligny LL, Deal C. Pediatric adrenocortical tumors: molecular events leading to insulin-like growth factor II gene overexpression. J Clin Endocrin Metab 2000;85: 2048-2056
    • (2000) J Clin Endocrin Metab , vol.85 , pp. 2048-2056
    • Wilkin, F.1    Gagné, N.2    Paquette, J.3    Oligny, L.L.4    Deal, C.5
  • 5
    • 51149100337 scopus 로고    scopus 로고
    • High frequency of loss of heterozygosity at 11p15 and IGF2 overexpression is not associated with clinical outcome in childhood adrenocortical tumors positive for the R337H TP53 mutation
    • Rosati R, Cerrato F, Doghman M, et al. High frequency of loss of heterozygosity at 11p15 and IGF2 overexpression is not associated with clinical outcome in childhood adrenocortical tumors positive for the R337H TP53 mutation. Cancer Genet Cytogenet 2008;186:19-24.
    • (2008) Cancer Genet Cytogenet , vol.186 , pp. 19-24
    • Rosati, R.1    Cerrato, F.2    Doghman, M.3
  • 6
    • 51649083560 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors
    • Almeida MQ, Fragoso MC, Lotfi CF, et al. Expression of insulin-like growth factor-II and its receptor in pediatric and adult adrenocortical tumors. J Clin Endocrinol Metab 2008;93:3524-3531
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3524-3531
    • Almeida, M.Q.1    Fragoso, M.C.2    Lotfi, C.F.3
  • 7
    • 58149381997 scopus 로고    scopus 로고
    • Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma
    • Barlaskar FM, Spalding AC, Heaton JH, et al. Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma. J Clin Endocrinol Metab 2009;94:204-212
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 204-212
    • Barlaskar, F.M.1    Spalding, A.C.2    Heaton, J.H.3
  • 8
    • 36849073202 scopus 로고    scopus 로고
    • Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer
    • Doghman M, Karpova T, Rodrigues GA, et al. Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer. Mol Endocrinol 2007;21:2968-2987
    • (2007) Mol Endocrinol , vol.21 , pp. 2968-2987
    • Doghman, M.1    Karpova, T.2    Rodrigues, G.A.3
  • 9
    • 67349157055 scopus 로고    scopus 로고
    • A matter of dosage: SF-1 in adrenocortical development and cancer
    • Doghman M, Lalli E. A matter of dosage: SF-1 in adrenocortical development and cancer. Ann Endocrinol 2009;70:148-152
    • (2009) Ann Endocrinol , vol.70 , pp. 148-152
    • Doghman, M.1    Lalli, E.2
  • 10
    • 33846683317 scopus 로고    scopus 로고
    • Gene expression profiling of childhood adrenocortical tumors
    • West A, Neale GA, Pounds S, et al. Gene expression profiling of childhood adrenocortical tumors. Cancer Res 2007;67:600-608
    • (2007) Cancer Res , vol.67 , pp. 600-608
    • West, A.1    Neale, G.A.2    Pounds, S.3
  • 11
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 13
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004;101:2999-3004.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 14
    • 34547763335 scopus 로고    scopus 로고
    • Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/-nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors
    • Doghman M, Arhatte M, Thibout H, et al. Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/-nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors. J Clin Endocrinol Metab 2007;92: 3253-3260
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3253-3260
    • Doghman, M.1    Arhatte, M.2    Thibout, H.3
  • 15
    • 0032789933 scopus 로고    scopus 로고
    • Autocrine role of IGF-II in proliferation of human adrenocortical carcinoma NCI H295R cell line
    • Logié A, Boulle N, Gaston V, et al. Autocrine role of IGF-II in proliferation of human adrenocortical carcinoma NCI H295R cell line. J Mol Endocrinol 1999;23:23-32.
    • (1999) J Mol Endocrinol , vol.23 , pp. 23-32
    • Logié, A.1    Boulle, N.2    Gaston, V.3
  • 16
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell 2007;12:9-22.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 17
    • 57349174174 scopus 로고    scopus 로고
    • Development of an adrenocorticotropin-responsive human adrenocortical carcinoma cell line
    • Parmar J, Key RE, Rainey WE. Development of an adrenocorticotropin- responsive human adrenocortical carcinoma cell line. J Clin Endocrinol Metab 2008;93:4542-4546
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4542-4546
    • Parmar, J.1    Key, R.E.2    Rainey, W.E.3
  • 18
    • 21144443076 scopus 로고    scopus 로고
    • Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF
    • Guba M, Yezhelyev M, Eichhorn ME, et al. Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF. Blood 2005;105:4463-4469
    • (2005) Blood , vol.105 , pp. 4463-4469
    • Guba, M.1    Yezhelyev, M.2    Eichhorn, M.E.3
  • 19
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature 2005;435:834-838
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 20
    • 72749126286 scopus 로고    scopus 로고
    • Integrative molecular bioinformatics study of human adrenocortical tumors: MicroRNA, tissue-specific target prediction, and pathway analysis
    • Tömböl Z, Szabó PM, Molnár V, et al. Integrative molecular bioinformatics study of human adrenocortical tumors: microRNA, tissue-specific target prediction, and pathway analysis. Endocr Relat Cancer 2009;16:895-906.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 895-906
    • Tömböl, Z.1    Szabó, P.M.2    Molnár, V.3
  • 21
    • 73349137922 scopus 로고    scopus 로고
    • miR-195 and miR-483-5p identified as predictors of poor prognosis in adrenocortical cancer
    • Soon PS, Tacon LJ, Gill AJ, et al. miR-195 and miR-483-5p identified as predictors of poor prognosis in adrenocortical cancer. Clin Cancer Res 2009;15:7684-7692
    • (2009) Clin Cancer Res , vol.15 , pp. 7684-7692
    • Soon, P.S.1    Tacon, L.J.2    Gill, A.J.3
  • 22
    • 34548746977 scopus 로고    scopus 로고
    • MicroRNA signatures in human ovarian cancer
    • Iorio MV, Visone R, Di Leva G, et al. MicroRNA signatures in human ovarian cancer. Cancer Res 2007;67:8699-8707
    • (2007) Cancer Res , vol.67 , pp. 8699-8707
    • Iorio, M.V.1    Visone, R.2    Di Leva, G.3
  • 23
    • 39049086391 scopus 로고    scopus 로고
    • MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN
    • Yang H, Kong W, He L, et al. MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res 2008;68:425-433
    • (2008) Cancer Res , vol.68 , pp. 425-433
    • Yang, H.1    Kong, W.2    He, L.3
  • 24
    • 50849137458 scopus 로고    scopus 로고
    • MicroRNA expression profiles in serous ovarian carcinoma
    • Nam EJ, Yoon H, Kim SW, et al. MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res 2008;14: 2690-2695
    • (2008) Clin Cancer Res , vol.14 , pp. 2690-2695
    • Nam, E.J.1    Yoon, H.2    Kim, S.W.3
  • 26
    • 34248187964 scopus 로고    scopus 로고
    • MicroRNA expression profiles in head and neck cancer cell lines
    • Tran N, McLean T, Zhang X, et al. MicroRNA expression profiles in head and neck cancer cell lines. Biochem Biophys Res Commun 2007;358:12-17
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 12-17
    • Tran, N.1    McLean, T.2    Zhang, X.3
  • 27
    • 52049121293 scopus 로고    scopus 로고
    • Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue
    • Wong TS, Liu XB, Wong BY, Ng RW, Yuen AP, Wei WI. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 2008;14:2588-2592
    • (2008) Clin Cancer Res , vol.14 , pp. 2588-2592
    • Wong, T.S.1    Liu, X.B.2    Wong, B.Y.3    Ng, R.W.4    Yuen, A.P.5    Wei, W.I.6
  • 28
  • 29
    • 48249150023 scopus 로고    scopus 로고
    • Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer
    • Yamada H, Yanagisawa K, Tokumaru S, et al. Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer. Genes Chrom Cancer 2008;47:810-818
    • (2008) Genes Chrom Cancer , vol.47 , pp. 810-818
    • Yamada, H.1    Yanagisawa, K.2    Tokumaru, S.3
  • 30
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 2004;18:1926-1945
    • (2004) Genes Dev , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 32
    • 33748471980 scopus 로고    scopus 로고
    • mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
    • Frias MA, Thoreen CC, Jaffe JD, et al. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr Biol 2006;16:1865-1870
    • (2006) Curr Biol , vol.16 , pp. 1865-1870
    • Frias, M.A.1    Thoreen, C.C.2    Jaffe, J.D.3
  • 33
    • 32944457518 scopus 로고    scopus 로고
    • mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
    • O'Reilly KE, Rojo F, She QB, et al. mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res 2006;66:1500-1508
    • (2006) Cancer Res , vol.66 , pp. 1500-1508
    • O'Reilly, K.E.1    Rojo, F.2    She, Q.B.3
  • 34
    • 33747819801 scopus 로고    scopus 로고
    • mTOR and cancer: Insights into a complex relationship
    • Sabatini DM. mTOR and cancer: insights into a complex relationship. Nat Rev Cancer 2006;6:729-734
    • (2006) Nat Rev Cancer , vol.6 , pp. 729-734
    • Sabatini, D.M.1
  • 35
    • 23044465986 scopus 로고    scopus 로고
    • AKT is highly phosphorylated in pheochromocytomas but not in benign adrenocortical tumors
    • Fassnacht M, Weismann D, Ebert S, et al. AKT is highly phosphorylated in pheochromocytomas but not in benign adrenocortical tumors. J Clin Endocrinol Metab 2005;90:4366-4370
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4366-4370
    • Fassnacht, M.1    Weismann, D.2    Ebert, S.3
  • 36
    • 0034489211 scopus 로고    scopus 로고
    • Expression of the angiogenesis markers vascular endothelial growth factor-A, thrombospondin-1, and platelet-derived endothelial cell growth factor in human sporadic adrenocortical tumors: Correlation with genotypic alterations
    • de Fraipont F, El Atifi M, Gicquel C, Bertagna X, Chambaz EM, Feige JJ. Expression of the angiogenesis markers vascular endothelial growth factor-A, thrombospondin-1, and platelet-derived endothelial cell growth factor in human sporadic adrenocortical tumors: correlation with genotypic alterations. J Clin Endocrinol Metab 2000;85:4734-4741
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4734-4741
    • De Fraipont, F.1    El Atifi, M.2    Gicquel, C.3    Bertagna, X.4    Chambaz, E.M.5    Feige, J.J.6
  • 37
    • 50949132066 scopus 로고    scopus 로고
    • Human cytomegalovirus infection alters the expression of cellular microRNA species that affect its replication
    • Wang FZ, Weber F, Croce C, Liu CG, Liao X, Pellett PE. Human cytomegalovirus infection alters the expression of cellular microRNA species that affect its replication. J Virol 2008;82:9065-9074
    • (2008) J Virol , vol.82 , pp. 9065-9074
    • Wang, F.Z.1    Weber, F.2    Croce, C.3    Liu, C.G.4    Liao, X.5    Pellett, P.E.6
  • 38
    • 40949137463 scopus 로고    scopus 로고
    • A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells
    • Yaba A, Bianchi V, Borini A, Johnson J. A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells. Reprod Sci 2008;15:128-138
    • (2008) Reprod Sci , vol.15 , pp. 128-138
    • Yaba, A.1    Bianchi, V.2    Borini, A.3    Johnson, J.4
  • 39
    • 60549112707 scopus 로고    scopus 로고
    • The serine 2481-autophosphorylated form of mammalian target of rapamycin (mTOR) is localized to midzone and midbody in dividing cancer cells
    • Vazquez-Martin A, Oliveras-Ferraros C, Bernadó L, López-Bonet E, Menendez JA. The serine 2481-autophosphorylated form of mammalian target of rapamycin (mTOR) is localized to midzone and midbody in dividing cancer cells. Biochem Biophys Res Commun 2009;380:638-643
    • (2009) Biochem Biophys Res Commun , vol.380 , pp. 638-643
    • Vazquez-Martin, A.1    Oliveras-Ferraros, C.2    Bernadó, L.3    López-Bonet, E.4    Menendez, J.A.5
  • 41
    • 33749000851 scopus 로고    scopus 로고
    • Depletion of type IA regulatory subunit (RIα) of protein kinase a (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency
    • Mavrakis M, Lippincott-Schwartz J, Stratakis CA, Bossis I. Depletion of type IA regulatory subunit (RIα) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Hum Mol Genet 2006;15:2962-2971
    • (2006) Hum Mol Genet , vol.15 , pp. 2962-2971
    • Mavrakis, M.1    Lippincott-Schwartz, J.2    Stratakis, C.A.3    Bossis, I.4
  • 42
    • 65949092330 scopus 로고    scopus 로고
    • MicroRNA signature of primary pigmented nodular adrenocortical disease: Clinical correlations and regulation ofWnt signaling
    • Iliopoulos D, Bimpaki EI, Nesterova M, Stratakis CA. MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation ofWnt signaling. Cancer Res 2009;69:3278-3282
    • (2009) Cancer Res , vol.69 , pp. 3278-3282
    • Iliopoulos, D.1    Bimpaki, E.I.2    Nesterova, M.3    Stratakis, C.A.4


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