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Volumn 28, Issue 1, 2014, Pages 138-146

Regulation of MEIS1 by distal enhancer elements in acute leukemia

Author keywords

comparative genomic analysis; enhancer elements; hematopoiesis; MEIS1

Indexed keywords

GREEN FLUORESCENT PROTEIN; HOMEODOMAIN PROTEIN; MEIS1 PROTEIN; TRANSCRIPTION FACTOR HOXA9; UNCLASSIFIED DRUG;

EID: 84891857803     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.260     Document Type: Article
Times cited : (16)

References (57)
  • 1
    • 0029082385 scopus 로고
    • Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice
    • Moskow JJ, Bullrich F, Huebner K, Daar IO, Buchberg AM. Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol Cell Biol 1995; 15: 5434-5443.
    • (1995) Mol Cell Biol , vol.15 , pp. 5434-5443
    • Moskow, J.J.1    Bullrich, F.2    Huebner, K.3    Daar, I.O.4    Buchberg, A.M.5
  • 3
    • 49449101077 scopus 로고    scopus 로고
    • Meis1 regulates the development of endothelial cells in zebrafish
    • Minehata K, Kawahara A, Suzuki T. meis1 regulates the development of endothelial cells in zebrafish. Biochem Biophys Res Commun 2008; 374: 647-652.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 647-652
    • Minehata, K.1    Kawahara, A.2    Suzuki, T.3
  • 4
    • 54449094316 scopus 로고    scopus 로고
    • Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease
    • Stankunas K, Shang C, Twu KY, Kao SC, Jenkins NA, Copeland NG et al. Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease. Circ Res 2008; 103: 702-709.
    • (2008) Circ Res , vol.103 , pp. 702-709
    • Stankunas, K.1    Shang, C.2    Twu, K.Y.3    Kao, S.C.4    Jenkins, N.A.5    Copeland, N.G.6
  • 5
    • 0036142691 scopus 로고    scopus 로고
    • Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny
    • DOI 10.1016/S0301-472X(01)00757-3, PII S0301472X01007573
    • Pineault N, Helgason CD, Lawrence HJ, Humphries RK. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol 2002; 30: 49-57. (Pubitemid 34059217)
    • (2002) Experimental Hematology , vol.30 , Issue.1 , pp. 49-57
    • Pineault, N.1    Helgason, C.D.2    Lawrence, H.J.3    Humphries, R.K.4
  • 6
    • 0036402593 scopus 로고    scopus 로고
    • Frequent co-expression of HoxA9 and Meis1 genes in infant acute lymphoblastic leukaemia with MLL rearrangement
    • DOI 10.1046/j.1365-2141.2002.03803.x
    • Imamura T, Morimoto A, Takanashi M, Hibi S, Sugimoto T, Ishii E et al. Frequent coexpression of HoxA9 and Meis1 genes in infant acute lymphoblastic leukaemia with MLL rearrangement. Br J Haematol 2002; 119: 119-121. (Pubitemid 35176508)
    • (2002) British Journal of Haematology , vol.119 , Issue.1 , pp. 119-121
    • Imamura, T.1    Morimoto, A.2    Takanashi, M.3    Hibi, S.4    Sugimoto, T.5    Ishii, E.6    Imashuku, S.7
  • 7
    • 0032981197 scopus 로고    scopus 로고
    • Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells
    • Kawagoe H, Humphries RK, Blair A, Sutherland HJ, Hogge DE. Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells. Leukemia 1999; 13: 687-698. (Pubitemid 29243618)
    • (1999) Leukemia , vol.13 , Issue.5 , pp. 687-698
    • Kawagoe, H.1    Humphries, R.K.2    Blair, A.3    Sutherland, H.J.4    Hogge, D.D.5
  • 8
  • 9
    • 0032715662 scopus 로고    scopus 로고
    • Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias
    • Lawrence HJ, Rozenfeld S, Cruz C, Matsukuma K, Kwong A, Komuves L et al. Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias. Leukemia 1999; 13: 1993-1999.
    • (1999) Leukemia , vol.13 , pp. 1993-1999
    • Lawrence, H.J.1    Rozenfeld, S.2    Cruz, C.3    Matsukuma, K.4    Kwong, A.5    Komuves, L.6
  • 10
    • 20844444316 scopus 로고    scopus 로고
    • New insights into MLL gene rearranged acute leukemias using gene expression profiling: Shared pathways, lineage commitment, and partner genes
    • DOI 10.1038/sj.leu.2403746
    • Kohlmann A, Schoch C, Dugas M, Schnittger S, Hiddemann W, Kern W et al. New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes. Leukemia 2005; 19: 953-964. (Pubitemid 40862005)
    • (2005) Leukemia , vol.19 , Issue.6 , pp. 953-964
    • Kohlmann, A.1    Schoch, C.2    Dugas, M.3    Schnittger, S.4    Hiddemann, W.5    Kern, W.6    Haferlach, T.7
  • 13
    • 35948964020 scopus 로고    scopus 로고
    • Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential
    • DOI 10.1101/gad.1602107
    • Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML. Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential. Genes Dev 2007; 21: 2762-2774. (Pubitemid 350070722)
    • (2007) Genes and Development , vol.21 , Issue.21 , pp. 2762-2774
    • Wong, P.1    Iwasaki, M.2    Somervaille, T.C.P.3    So, C.W.E.4    Cleary, M.L.5
  • 14
    • 79960032630 scopus 로고    scopus 로고
    • Cell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex
    • Heuser M, Yun H, Berg T, Yung E, Argiropoulos B, Kuchenbauer F et al. Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. Cancer Cell 2011; 20: 39-52.
    • (2011) Cancer Cell , vol.20 , pp. 39-52
    • Heuser, M.1    Yun, H.2    Berg, T.3    Yung, E.4    Argiropoulos, B.5    Kuchenbauer, F.6
  • 15
    • 17144372606 scopus 로고    scopus 로고
    • Transplantable cell lines generated with NUP98-Hox fusion genes undergo leukemic progression by Meis1 independent of its binding to DNA
    • DOI 10.1038/sj.leu.2403696
    • Pineault N, Abramovich C, Humphries RK. Transplantable cell lines generated with NUP98-Hox fusion genes undergo leukemic progression by Meis1 independent of its binding to DNA. Leukemia 2005; 19: 636-643. (Pubitemid 40521169)
    • (2005) Leukemia , vol.19 , Issue.4 , pp. 636-643
    • Peneault, N.1    Abramovich, C.2    Humphries, R.K.3
  • 16
    • 84859635323 scopus 로고    scopus 로고
    • Downregulation of MEIS1 impairs long-term expansion of CD34\+ NPM1-mutated acute myeloid leukemia cells
    • Woolthuis CM, Han L, Verkaik-Schakel RN, Van Gosliga D, Kluin PM, Vellenga E et al. Downregulation of MEIS1 impairs long-term expansion of CD34\+ NPM1-mutated acute myeloid leukemia cells. Leukemia 2012; 26: 848-853.
    • (2012) Leukemia , vol.26 , pp. 848-853
    • Woolthuis, C.M.1    Han, L.2    Verkaik-Schakel, R.N.3    Van Gosliga, D.4    Kluin, P.M.5    Vellenga, E.6
  • 17
    • 77951742701 scopus 로고    scopus 로고
    • Meis1 maintains stemness signature in MLL-AF9 leukemia
    • Kumar AR, Sarver AL, Wu B, Kersey JH. Meis1 maintains stemness signature in MLL-AF9 leukemia. Blood 2010; 115: 3642-3643.
    • (2010) Blood , vol.115 , pp. 3642-3643
    • Kumar, A.R.1    Sarver, A.L.2    Wu, B.3    Kersey, J.H.4
  • 18
    • 79956367111 scopus 로고    scopus 로고
    • Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation
    • Orlovsky K, Kalinkovich A, Rozovskaia T, Shezen E, Itkin T, Alder H et al. Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation. Proc Natl Acad Sci USA 2011; 108: 7956-7961.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 7956-7961
    • Orlovsky, K.1    Kalinkovich, A.2    Rozovskaia, T.3    Shezen, E.4    Itkin, T.5    Alder, H.6
  • 19
    • 0031194634 scopus 로고    scopus 로고
    • Cloning and mapping of the MEIS1 gene, the human homolog of a murine leukemogenic gene
    • DOI 10.1006/geno.1997.4766
    • Smith Jr JE, Bollekens JA, Inghirami G, Takeshita K. Cloning and mapping of the MEIS1 gene, the human homolog of a murine leukemogenic gene. Genomics 1997; 43: 99-103. (Pubitemid 27310529)
    • (1997) Genomics , vol.43 , Issue.1 , pp. 99-103
    • Smith Jr., J.E.1    Bollekens, J.A.2    Inghirami, G.3    Takeshita, K.4
  • 20
    • 77955493246 scopus 로고    scopus 로고
    • Identification of E74-like factor 1 (ELF1) as a transcriptional regulator of the Hox cofactor MEIS1
    • Xiang P, Lo C, Argiropoulos B, Lai CB, Rouhi A, Imren S et al. Identification of E74-like factor 1 (ELF1) as a transcriptional regulator of the Hox cofactor MEIS1. Exp Hematol 2010; 38: 808 e791-792.
    • (2010) Exp Hematol , vol.38 , Issue.808
    • Xiang, P.1    Lo, C.2    Argiropoulos, B.3    Lai, C.B.4    Rouhi, A.5    Imren, S.6
  • 21
    • 40749115192 scopus 로고    scopus 로고
    • CREB regulates Meis1 expression in normal and malignant hematopoietic cells [14]
    • DOI 10.1038/sj.leu.2404933, PII 2404933
    • Esparza SD, Chang J, Shankar DB, Zhang B, Nelson SF, Sakamoto KM et al. CREB regulates Meis1 expression in normal and malignant hematopoietic cells. Leukemia 2008; 22: 665-667. (Pubitemid 351386747)
    • (2008) Leukemia , vol.22 , Issue.3 , pp. 665-667
    • Esparza, S.D.1    Chang, J.2    Shankar, D.B.3    Zhang, B.4    Nelson, S.F.5    Sakamoto, K.M.6
  • 22
    • 77957348625 scopus 로고    scopus 로고
    • Combinatorial transcriptional control in blood stem/progenitor cells: Genome-wide analysis of ten major transcriptional regulators
    • Wilson NK, Foster SD, Wang X, Knezevic K, Schutte J, Kaimakis P et al. Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell 2010; 7: 532-544.
    • (2010) Cell Stem Cell , vol.7 , pp. 532-544
    • Wilson, N.K.1    Foster, S.D.2    Wang, X.3    Knezevic, K.4    Schutte, J.5    Kaimakis, P.6
  • 23
    • 3042740671 scopus 로고    scopus 로고
    • Comparative genomics at the vertebrate extremes
    • DOI 10.1038/nrg1350
    • Boffelli D, Nobrega MA, Rubin EM et al. Comparative genomics at the vertebrate extremes. Nat Rev Genet 2004; 5: 456-465. (Pubitemid 38915412)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.6 , pp. 456-465
    • Boffelli, D.1    Nobrega, M.A.2    Rubin, E.M.3
  • 28
    • 34347244234 scopus 로고    scopus 로고
    • Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish
    • Fisher S, Grice EA, Vinton RM, Bessling SL, Urasaki A, Kawakami K et al. Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish. Nat Protoc 2006; 1: 1297-1305.
    • (2006) Nat Protoc , vol.1 , pp. 1297-1305
    • Fisher, S.1    Grice, E.A.2    Vinton, R.M.3    Bessling, S.L.4    Urasaki, A.5    Kawakami, K.6
  • 29
    • 84864548794 scopus 로고    scopus 로고
    • Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells
    • Zhang Y, Yan X, Sashida G, Zhao X, Rao Y, Goyama S et al. Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells. Blood 2012; 120: 1118-1129.
    • (2012) Blood , vol.120 , pp. 1118-1129
    • Zhang, Y.1    Yan, X.2    Sashida, G.3    Zhao, X.4    Rao, Y.5    Goyama, S.6
  • 30
    • 0344466803 scopus 로고    scopus 로고
    • The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator
    • Schreiner SA, Garcia-Cuellar MP, Fey GH, Slany RK. The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator. Leukemia 1999; 13: 1525-1533. (Pubitemid 29465614)
    • (1999) Leukemia , vol.13 , Issue.10 , pp. 1525-1533
    • Schreiner, S.A.1    Garcia-Cuellar, M.P.2    Fey, G.H.3    Slany, R.K.4
  • 31
    • 79959514392 scopus 로고    scopus 로고
    • MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome
    • Wang QF, Wu G, Mi S, He F, Wu J, Dong J et al. MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome. Blood 2011; 117: 6895-6905.
    • (2011) Blood , vol.117 , pp. 6895-6905
    • Wang, Q.F.1    Wu, G.2    Mi, S.3    He, F.4    Wu, J.5    Dong, J.6
  • 33
    • 33745152719 scopus 로고    scopus 로고
    • Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression
    • Blanchette M, Bataille AR, Chen X, Poitras C, Laganiere J, Lefebvre C et al. Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression. Genome Res 2006; 16: 656-668.
    • (2006) Genome Res , vol.16 , pp. 656-668
    • Blanchette, M.1    Bataille, A.R.2    Chen, X.3    Poitras, C.4    Laganiere, J.5    Lefebvre, C.6
  • 34
    • 3242878193 scopus 로고    scopus 로고
    • ECR Browser: A tool for visualizing and accessing data from comparisons of multiple vertebrate genomes
    • DOI 10.1093/nar/gkh355
    • Ovcharenko I, Nobrega MA, Loots GG, Stubbs L. ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucleic Acids Res 2004; 32: W280-W286. (Pubitemid 38997344)
    • (2004) Nucleic Acids Research , vol.32 , Issue.WEB SERVER ISS.
    • Ovcharenko, I.1    Nobrega, M.A.2    Loots, G.G.3    Stubbs, L.4
  • 36
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, Harp LF et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 2009; 459: 108-112.
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1    Hon, G.C.2    Hawkins, R.D.3    Kheradpour, P.4    Stark, A.5    Harp, L.F.6
  • 41
    • 0038518208 scopus 로고    scopus 로고
    • Virology. Picking the right spot
    • Trono D. Virology. Picking the right spot. Science 2003; 300: 1670-1671.
    • (2003) Science , vol.300 , pp. 1670-1671
    • Trono, D.1
  • 46
    • 24144500001 scopus 로고    scopus 로고
    • Zebrafish as a model for myelopoiesis during embryogenesis
    • DOI 10.1016/j.exphem.2005.06.010, PII S0301472X05002924
    • Berman JN, Kanki JP, Look AT. Zebrafish as a model for myelopoiesis during embryogenesis. Exp Hematol 2005; 33: 997-1006. (Pubitemid 41226498)
    • (2005) Experimental Hematology , vol.33 , Issue.9 SPEC. ISS. , pp. 997-1006
    • Berman, J.N.1    Kanki, J.P.2    Look, A.T.3
  • 47
    • 18244392936 scopus 로고    scopus 로고
    • Scl is required for dorsal aorta as well as blood formation in zebrafish embryos
    • DOI 10.1182/blood-2004-09-3547
    • Patterson LJ, Gering M, Patient R. Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood 2005; 105: 3502-3511. (Pubitemid 40628192)
    • (2005) Blood , vol.105 , Issue.9 , pp. 3502-3511
    • Patterson, L.J.1    Gering, M.2    Patient, R.3
  • 48
    • 0035829517 scopus 로고    scopus 로고
    • Gridlock signalling pathway fashions the first embryonic artery
    • DOI 10.1038/35102599
    • Zhong TP, Childs S, Leu JP, Fishman MC. Gridlock signalling pathway fashions the first embryonic artery. Nature 2001; 414: 216-220. (Pubitemid 33051237)
    • (2001) Nature , vol.414 , Issue.6860 , pp. 216-220
    • Zhong, T.P.1    Childs, S.2    Leu, J.P.3    Fishman, M.C.4
  • 49
    • 0033780145 scopus 로고    scopus 로고
    • Building the vertebrate vasculature: Research is going swimmingly
    • Roman BL, Weinstein BM. Building the vertebrate vasculature: research is going swimmingly. Bioessays 2000; 22: 882-893.
    • (2000) Bioessays , vol.22 , pp. 882-893
    • Roman, B.L.1    Weinstein, B.M.2
  • 50
    • 39049086371 scopus 로고    scopus 로고
    • Qualifying the relationship between sequence conservation and molecular function
    • DOI 10.1101/gr.7205808
    • Cooper GM, Brown CD. Qualifying the relationship between sequence conservation and molecular function. Genome Res 2008; 18: 201-205. (Pubitemid 351240729)
    • (2008) Genome Research , vol.18 , Issue.2 , pp. 201-205
    • Cooper, G.M.1    Brown, C.D.2
  • 52
    • 39049147650 scopus 로고    scopus 로고
    • Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b
    • DOI 10.1101/gr.6929408
    • Mcgaughey DM, Vinton RM, Huynh J, Al-Saif A, Beer MA, Mccallion AS et al. Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b. Genome Res 2008; 18: 252-260. (Pubitemid 351240735)
    • (2008) Genome Research , vol.18 , Issue.2 , pp. 252-260
    • McGaughey, D.M.1    Vinton, R.M.2    Huynh, J.3    Al-Saif, A.4    Beer, M.A.5    McCallion, A.S.6
  • 53
    • 77949977555 scopus 로고    scopus 로고
    • Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
    • Ghisletti S, Barozzi I, Mietton F, Polletti S, De Santa F, Venturini E et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 2010; 32: 317-328.
    • (2010) Immunity , vol.32 , pp. 317-328
    • Ghisletti, S.1    Barozzi, I.2    Mietton, F.3    Polletti, S.4    De Santa, F.5    Venturini, E.6
  • 54
    • 70249100266 scopus 로고    scopus 로고
    • HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis
    • Hu YL, Fong S, Ferrell C, Largman C, Shen WF. HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis. Mol Cell Biol 2009; 29: 5181-5192.
    • (2009) Mol Cell Biol , vol.29 , pp. 5181-5192
    • Hu, Y.L.1    Fong, S.2    Ferrell, C.3    Largman, C.4    Shen, W.F.5
  • 56
    • 84862966022 scopus 로고    scopus 로고
    • Identification and characterization of Hoxa9 binding sites in hematopoietic cells
    • Huang Y, Sitwala K, Bronstein J, Sanders D, Dandekar M, Collins C et al. Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood 2012; 119: 388-398.
    • (2012) Blood , vol.119 , pp. 388-398
    • Huang, Y.1    Sitwala, K.2    Bronstein, J.3    Sanders, D.4    Dandekar, M.5    Collins, C.6
  • 57
    • 33645871853 scopus 로고    scopus 로고
    • An autoregulatory element maintains HOXA10 expression in endometrial epithelial cells
    • Discussion 1107-1109
    • Kelly M, Daftary G, Taylor HS. An autoregulatory element maintains HOXA10 expression in endometrial epithelial cells. Am J Obstet Gynecol 2006; 194: 1100-1107, Discussion 1107-1109.
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 1100-1107
    • Kelly, M.1    Daftary, G.2    Taylor, H.S.3


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