Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain

Pain

Volumn 155, Issue 1, 2014, Pages 28-36

  Ungard, Robert G ^a   Seidlitz, Eric P ^a   Singh, Gurmit ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Bone; Cancer; Cancer induced bone pain; Glutamate; Nociception; Sulfasalazine; System x C

Indexed keywords

4 CARBOXYPHENYLGLYCINE; GLUTAMATE TRANSPORTER; SALAZOSULFAPYRIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METASTASIS; BONE PAIN; BREAST ADENOCARCINOMA; CANCER CELL; CANCER PAIN; CONTROLLED STUDY; DRUG INHIBITION; ENZYME INHIBITION; ENZYME RELEASE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

BONE; CANCER; CANCER-INDUCED BONE PAIN; GLUTAMATE; NOCICEPTION; SULFASALAZINE; SYSTEM X(C)(-);

ADENOCARCINOMA; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOATES; BONE AND BONES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLUTAMIC ACID; GLYCINE; HUMANS; MICE; MICE, NUDE; PAIN; PAIN MEASUREMENT; SULFASALAZINE; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84891835737     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.08.030     Document Type: Article

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