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Volumn 343, Issue 2, 2014, Pages 156-160

Targeted therapy in metastatic renal carcinoma

Author keywords

Adjuvant treatment; Metastatic disease; Renal cell carcinoma; Renal tumor; Target therapy

Indexed keywords

AXITINIB; BEVACIZUMAB; CEDIRANIB; ERLOTINIB; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PAZOPANIB; PLACEBO; RAPAMYCIN; RECOMBINANT ALPHA INTERFERON; SORAFENIB; SUNITINIB; TEMSIROLIMUS; VASCULOTROPIN;

EID: 84891829996     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.09.038     Document Type: Review
Times cited : (37)

References (40)
  • 1
    • 84871773566 scopus 로고    scopus 로고
    • Novel agents in renal carcinoma: a reality check
    • Najjar Y., Rini B. Novel agents in renal carcinoma: a reality check. Ther. Adv. Med. Oncol. 2012, 4(4):183-194.
    • (2012) Ther. Adv. Med. Oncol. , vol.4 , Issue.4 , pp. 183-194
    • Najjar, Y.1    Rini, B.2
  • 2
    • 28044434622 scopus 로고    scopus 로고
    • Targeted agents for the treatment of advanced renal cell carcinoma
    • Stadler W. Targeted agents for the treatment of advanced renal cell carcinoma. Cancer 2005, 104(11):2323-2333.
    • (2005) Cancer , vol.104 , Issue.11 , pp. 2323-2333
    • Stadler, W.1
  • 3
    • 0034119151 scopus 로고    scopus 로고
    • Novel investigative approaches for advanced renal cell carcinoma
    • Berg W., Divgi C., Nanus D., Motzer R. Novel investigative approaches for advanced renal cell carcinoma. Semin. Oncol. 2000, 27(2):234-239.
    • (2000) Semin. Oncol. , vol.27 , Issue.2 , pp. 234-239
    • Berg, W.1    Divgi, C.2    Nanus, D.3    Motzer, R.4
  • 5
    • 0034981265 scopus 로고    scopus 로고
    • Rasregulation of vascular endothelial growth factor and angiogenesis
    • Janusz R., Robert S. Rasregulation of vascular endothelial growth factor and angiogenesis. Methods Enzymol. 2001, 333:267-283.
    • (2001) Methods Enzymol. , vol.333 , pp. 267-283
    • Janusz, R.1    Robert, S.2
  • 6
    • 0036983115 scopus 로고    scopus 로고
    • The Ras-Raf-MEK-ERK pathway in the treatment of cancer
    • Hilger R., Scheulen M., Strumberg D. The Ras-Raf-MEK-ERK pathway in the treatment of cancer. Onkologie 2002 December, 25(6):511-518.
    • (2002) Onkologie , vol.25 , Issue.6 , pp. 511-518
    • Hilger, R.1    Scheulen, M.2    Strumberg, D.3
  • 8
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier B., Eisen T., Stadler W.M., et al. Sorafenib in advanced clear-cell renal-cell carcinoma. New Engl. J. Med. 2007, 356(2):125-134.
    • (2007) New Engl. J. Med. , vol.356 , Issue.2 , pp. 125-134
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 9
    • 33744984843 scopus 로고    scopus 로고
    • Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma
    • Ratain M.J., Eisen T., Stadler W.M., et al. Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. J. Clin. Oncol. 2006, 24(16):2505-2512.
    • (2006) J. Clin. Oncol. , vol.24 , Issue.16 , pp. 2505-2512
    • Ratain, M.J.1    Eisen, T.2    Stadler, W.M.3
  • 10
    • 33744954585 scopus 로고    scopus 로고
    • Sunitinib in patients with metastatic renal cell carcinoma
    • Motzer R., Rini B., Bukowski R., et al. Sunitinib in patients with metastatic renal cell carcinoma. JAMA 2006, 295(21):2516-2524.
    • (2006) JAMA , vol.295 , Issue.21 , pp. 2516-2524
    • Motzer, R.1    Rini, B.2    Bukowski, R.3
  • 12
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer R., Hutson T., Tomczak P., et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. New Engl. J. Med. 2007, 356(2):115-124.
    • (2007) New Engl. J. Med. , vol.356 , Issue.2 , pp. 115-124
    • Motzer, R.1    Hutson, T.2    Tomczak, P.3
  • 13
    • 49249133069 scopus 로고    scopus 로고
    • Quality of life in patients with metastatic renal cell carcinoma treated with sunitinib or interferon alfa: results from a phase III randomized trial
    • Cella D., Li J., Cappelleri J., et al. Quality of life in patients with metastatic renal cell carcinoma treated with sunitinib or interferon alfa: results from a phase III randomized trial. J. Clin. Oncol. 2008, 26(22):3763-3769.
    • (2008) J. Clin. Oncol. , vol.26 , Issue.22 , pp. 3763-3769
    • Cella, D.1    Li, J.2    Cappelleri, J.3
  • 15
    • 79953864160 scopus 로고    scopus 로고
    • Pazopanib for the treatment of renal cancer
    • Al-Marrawi M., Rini B. Pazopanib for the treatment of renal cancer. Expert Opin. Pharmacother. 2011, 12(7):1171-1189.
    • (2011) Expert Opin. Pharmacother. , vol.12 , Issue.7 , pp. 1171-1189
    • Al-Marrawi, M.1    Rini, B.2
  • 16
    • 80455129407 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors in the treatment of advanced renal cell carcinoma: focus on pazopanib
    • Vasudev N.S., Larkin J.M. Tyrosine kinase inhibitors in the treatment of advanced renal cell carcinoma: focus on pazopanib. Clin. Med. Insights Oncol. 2011, 5:333-342.
    • (2011) Clin. Med. Insights Oncol. , vol.5 , pp. 333-342
    • Vasudev, N.S.1    Larkin, J.M.2
  • 17
    • 84874527525 scopus 로고    scopus 로고
    • Third generation tyrosine kinase inhibitors and their development in advanced renal cell carcinoma
    • Bukowski R. Third generation tyrosine kinase inhibitors and their development in advanced renal cell carcinoma. Front Oncol. 2012, 2:13.
    • (2012) Front Oncol. , vol.2 , pp. 13
    • Bukowski, R.1
  • 18
    • 79952543555 scopus 로고    scopus 로고
    • Pazopanib: the newest tyrosine kinase inhibitor for the treatment of advanced or metastatic renal cell carcinoma
    • Keisner S., Shah S. Pazopanib: the newest tyrosine kinase inhibitor for the treatment of advanced or metastatic renal cell carcinoma. Drugs 2011, 71(4):443-454.
    • (2011) Drugs , vol.71 , Issue.4 , pp. 443-454
    • Keisner, S.1    Shah, S.2
  • 19
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial
    • Epub 2010 January 25
    • Sternberg C., Davis I., Mardiak J., et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J. Clin. Oncol. 2010 February 20, 28(6):1061-1068. Epub 2010 January 25.
    • (2010) J. Clin. Oncol. , vol.28 , Issue.6 , pp. 1061-1068
    • Sternberg, C.1    Davis, I.2    Mardiak, J.3
  • 21
    • 84862114798 scopus 로고    scopus 로고
    • Comprehensive overview of axitinib development in solid malignancies: focus on metastatic renal cell carcinoma
    • Carmichael C., Lau C., Josephson D., Pal S. Comprehensive overview of axitinib development in solid malignancies: focus on metastatic renal cell carcinoma. Clin. Adv. Hematol. Oncol. 2012, 10(5):307-314.
    • (2012) Clin. Adv. Hematol. Oncol. , vol.10 , Issue.5 , pp. 307-314
    • Carmichael, C.1    Lau, C.2    Josephson, D.3    Pal, S.4
  • 22
    • 35448934762 scopus 로고    scopus 로고
    • Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study
    • Rixe O., Bukowski R., Michaelson M., et al. Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study. Lancet Oncol. 2007, 8(11):975-984.
    • (2007) Lancet Oncol. , vol.8 , Issue.11 , pp. 975-984
    • Rixe, O.1    Bukowski, R.2    Michaelson, M.3
  • 23
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial
    • Rini B., Escudier B., Tomczak P., et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet 2011, 378(9807):1931-1939.
    • (2011) Lancet , vol.378 , Issue.9807 , pp. 1931-1939
    • Rini, B.1    Escudier, B.2    Tomczak, P.3
  • 24
    • 84857052966 scopus 로고    scopus 로고
    • Cediranib monotherapy in patients with advanced renal cell carcinoma: results of a randomised phase II study
    • Mulders P., Hawkins R., Nathan P., et al. Cediranib monotherapy in patients with advanced renal cell carcinoma: results of a randomised phase II study. Eur. J. Cancer 2012, 48(4):527-537.
    • (2012) Eur. J. Cancer , vol.48 , Issue.4 , pp. 527-537
    • Mulders, P.1    Hawkins, R.2    Nathan, P.3
  • 25
    • 56749161699 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
    • Rini B., Halabi S., Rosenberg J., et al. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. J. Clin. Oncol. 2008, 26(33):5422-5428.
    • (2008) J. Clin. Oncol. , vol.26 , Issue.33 , pp. 5422-5428
    • Rini, B.1    Halabi, S.2    Rosenberg, J.3
  • 26
    • 77952300540 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival
    • Escudier B., Bellmunt J., Négrier S., et al. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J. Clin. Oncol. 2010, 28(13):2144-2150.
    • (2010) J. Clin. Oncol. , vol.28 , Issue.13 , pp. 2144-2150
    • Escudier, B.1    Bellmunt, J.2    Négrier, S.3
  • 27
    • 33144463758 scopus 로고    scopus 로고
    • A review of erlotinib and its clinical use
    • P Tang, M Tsao, M Moore A review of erlotinib and its clinical use. Expert Opin. February 2006, (7):177-193.
    • (2006) Expert Opin. , Issue.7 , pp. 177-193
    • Tang, P.1    Tsao, M.2    Moore, M.3
  • 28
    • 30944452354 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib
    • ( 2005 by American Society of Clinical Oncology)
    • Hainsworth J., Sosman J., Spigel D., Edwards D., Baughman C., Greco A. Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib. J. Clin. Oncol. 2005, 23:7889-7896. ( 2005 by American Society of Clinical Oncology).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7889-7896
    • Hainsworth, J.1    Sosman, J.2    Spigel, D.3    Edwards, D.4    Baughman, C.5    Greco, A.6
  • 29
    • 35648938219 scopus 로고    scopus 로고
    • Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer
    • ( 2007 by American Society of Clinical Oncology)
    • Bukowski R.M., Kabbinavar F.F., Figlin R.A., et al. Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer. J. Clin. Oncol. 2007, 25:4536-4541. ( 2007 by American Society of Clinical Oncology).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4536-4541
    • Bukowski, R.M.1    Kabbinavar, F.F.2    Figlin, R.A.3
  • 30
    • 77956439852 scopus 로고    scopus 로고
    • Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib
    • Flaig T., Costa L., Gustafson D., et al. Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib. Br. J. Cancer 2010, 103:796-801.
    • (2010) Br. J. Cancer , vol.103 , pp. 796-801
    • Flaig, T.1    Costa, L.2    Gustafson, D.3
  • 31
    • 84866948962 scopus 로고    scopus 로고
    • Biomarkers: the next therapeutic hurdle in metastatic renal cell carcinoma
    • Sonpavde G., Choueiri T. Biomarkers: the next therapeutic hurdle in metastatic renal cell carcinoma. Br. J. Cancer 2012, 107(7):1009-1016.
    • (2012) Br. J. Cancer , vol.107 , Issue.7 , pp. 1009-1016
    • Sonpavde, G.1    Choueiri, T.2
  • 32
    • 79960364349 scopus 로고    scopus 로고
    • Future directions in renal cell carcinoma: 2011 and beyond
    • Cho D., Atkins M. Future directions in renal cell carcinoma: 2011 and beyond. Hematol. Oncol. Clin. North Am. 2011, 25(4):917-935.
    • (2011) Hematol. Oncol. Clin. North Am. , vol.25 , Issue.4 , pp. 917-935
    • Cho, D.1    Atkins, M.2
  • 33
    • 84862986202 scopus 로고    scopus 로고
    • MTOR pathway inhibition in renal cell carcinoma
    • (Epub 2010 March 5)
    • Pinto M., Redondo S., Espinosa A., Zamora A., Castelo F., González B. mTOR pathway inhibition in renal cell carcinoma. Urol. Oncol. July-August 2012, 30(4):356-361. (Epub 2010 March 5).
    • (2012) Urol. Oncol. , vol.30 , Issue.4 , pp. 356-361
    • Pinto, M.1    Redondo, S.2    Espinosa, A.3    Zamora, A.4    Castelo, F.5    González, B.6
  • 34
  • 35
    • 79953889736 scopus 로고    scopus 로고
    • Everolimus for the treatment of advanced renal cell carcinoma
    • Amato R. Everolimus for the treatment of advanced renal cell carcinoma. Expert Opin. Pharmacother. 2011, 12(7):1143-1155.
    • (2011) Expert Opin. Pharmacother. , vol.12 , Issue.7 , pp. 1143-1155
    • Amato, R.1
  • 36
    • 77952301116 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and everolimus in patients with advanced renal cell carcinoma
    • (Epub 2010 April 5)
    • Spigel D.R., Anthony Greco F., Waterhouse D.M., et al. Phase II trial of bevacizumab and everolimus in patients with advanced renal cell carcinoma. J. Clin. Oncol. May 1 2010, 28(13):2131-2136. (Epub 2010 April 5).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.13 , pp. 2131-2136
    • Spigel, D.R.1    Anthony Greco, F.2    Waterhouse, D.M.3
  • 37
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial
    • Motzer R., Escudier B., Oudard S., et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 2008, 372(9637):449-456.
    • (2008) Lancet , vol.372 , Issue.9637 , pp. 449-456
    • Motzer, R.1    Escudier, B.2    Oudard, S.3
  • 38
    • 34548528069 scopus 로고    scopus 로고
    • Negrier Sea. Phase I/II trial of temsirolimus combined with interferon alfa for advanced renal cell carcinoma
    • Motzer R., Hudes G., Curti B., McDermott D., Escudier B. Negrier Sea. Phase I/II trial of temsirolimus combined with interferon alfa for advanced renal cell carcinoma. J. Clin. Oncol. 2007, 25(25):3958-3964.
    • (2007) J. Clin. Oncol. , vol.25 , Issue.25 , pp. 3958-3964
    • Motzer, R.1    Hudes, G.2    Curti, B.3    McDermott, D.4    Escudier, B.5
  • 39
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • Hudes G., Carducci M., Tomczak P., et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. New Engl. J. Med. 2007, 356(22):2271-2281.
    • (2007) New Engl. J. Med. , vol.356 , Issue.22 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3


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