Maternal folate exposure in pregnancy and childhood asthma and allergy: A systematic review

Nutrition Reviews

Volumn 72, Issue 1, 2014, Pages 55-64

  Brown, Susan B ^a   Reeves, Katherine W ^a   Bertone Johnson, Elizabeth R ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Childhood allergy; Childhood asthma; Folate; Folic acid; Pregnancy

Indexed keywords

FOLIC ACID;

AIRWAY OBSTRUCTION; ALLERGY; ARTICLE; ASTHMA; ATOPIC DERMATITIS; ATOPY; CHEST TIGHTNESS; COUGHING; DIET SUPPLEMENTATION; DIETARY REFERENCE INTAKE; DISEASE ASSOCIATION; DNA METHYLATION; DYSPNEA; ECZEMA; ENVIRONMENTAL EXPOSURE; FIRST TRIMESTER PREGNANCY; FOLATE METABOLISM; FOLIC ACID BLOOD LEVEL; HUMAN; IMMUNIZATION; LOWER RESPIRATORY TRACT INFECTION; LUNG INFLATION; MATERNAL NUTRITION; NEURAL TUBE DEFECT; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PREGNANCY OUTCOME; PRENATAL EXPOSURE; RESPIRATORY TRACT INFLAMMATION; RISK REDUCTION; SECOND TRIMESTER PREGNANCY; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW; SYSTEMATIC REVIEW (TOPIC); THIRD TRIMESTER PREGNANCY; WHEEZING;

ASTHMA; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; HUMANS; HYPERSENSITIVITY; MATERNAL EXPOSURE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROSPECTIVE STUDIES; VITAMIN B COMPLEX;

EID: 84891829440     PISSN: 00296643     EISSN: 17534887     Source Type: Journal    
DOI: 10.1111/nure.12080     Document Type: Article

References (41)

1. Wehby GL, Murray JC. The effects of prenatal use of folic acid and other dietary supplements on early child development. Matern Child Health J. 2008;12:180-187.
2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington DC: National Academy Press; 1998.
3. US Preventive Services Task Force. Folic acid for the prevention of neural tube defects: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2009;150:626-631.
4. Bailey LB. New standard for dietary folate intake in pregnant women. Am J Clin Nutr. 2000;71(Suppl 5):S1304-S1307.
5. Hoyo C, Murtha AP, Schildkraut JM, etal. Folic acid supplementation before and during pregnancy in the Newborn Epigenetics Study. BMC Public Health. 2011;11:1-8.
6. Lumley J, Watson L, Watson M, etal. Periconceptional supplementation with folate and/or multivitamins for preventing neural tube defects. Cochrane Database Syst Rev. 2001;(3):CD001056.
7. Suitor CW, Bailey LB. Dietary folate equivalents: interpretation and application. J Am Diet Assoc. 2000;100:88-94.
8. Crider KS, Bailey LB, Berry RJ. Folic acid food fortification - its history, effect, concerns, and future directions. Nutrients. 2011;3:370-384.
9. Adams T, Jeffreson S. Australia implements voluntary folate fortification. Am J Public Health. 1996;86:593-594.
10. Brown RD, Langshaw MW, Uhr EJ, etal. The impact of mandatory fortification of flour with folic acid on the blood folate levels of an Australian population. Med J Aust. 2011;194:65-67.
11. Wald NJ, Law MR, Morris JK, etal. Quantifying the effect of folic acid. Lancet. 2001;358:2069-2073.
12. Devereux G. Allergic disease: nutrition as a potential determinant of asthma. Proc Nutr Soc. 2010;69:1-10.
13. Moffatt MF, Gut IG, Demanais F, etal. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med. 2010;363:1211-1221.
14. Van Wonderen KE, Van Der Mark LB, Mohrs J, etal. Different definitions in childhood asthma: how dependable is the dependent variable? Eur Respir J. 2010;36:48-56.
15. Dodig S, Richter D, Zrinski-Topic R. Inflammatory markers in childhood asthma. Clin Chem Lab Med. 2011;49:587-599.
16. Allan K, Devereux G. Diet and asthma: nutrition implications from prevention to treatment. J Am Diet Assoc. 2011;111:258-268.
17. Matsui EC, Matsui W. Higher serum folate levels are associated with a lower risk of atopy and wheeze. J Allergy Clin Immunol. 2009;123:1253-1259.
18. Litonjua AA, Rifas-Shiman SL, Ly NP, etal. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 years of age. Am J Clin Nutr. 2006;84:903-911.
19. Kim JH, Ellwood PE, Asher MI. Diet and asthma: looking back, moving forward. Respir Res. 2009;10:1-7.
20. Husemoen LLN, Toft U, Fenger M, etal. The association between atopy and factors influencing folate metabolism: is the low folate status causally related to the development of atopy? Int J Epidemiol. 2006;35:954-961.
21. Hollingsworth JW, Maruoka S, Boon K, etal. In utero supplementation with methyl donors enhances allergic airway disease in mice. J Clin Invest. 2008;118:3462-3469.
22. Chmurzynska A. Fetal programming: link between early nutrition, DNA methylation, and complex diseases. Nutr Rev. 2010;68:87-98.
23. Martino DJ, Prescott SL. Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease. Allergy. 2010;65:7-15.
24. Virchow JC. Asthma and pregnancy. Semin Respir Crit Care Med. 2012;33:630-644.
25. Granell R, Heron J, Lewis S, etal. The association between mother and child MTHFR C677T polymorphisms, dietary folate intake and childhood atopy in a population-based, longitudinal birth cohort. Clin Exp Allergy. 2008;38:320-328.
26. Sibani S, Melnyk S, Pogribny IP, etal. Studies of methionine cycle intermediates (SAM, SAH), DNA methylation, and the impact of folate deficiency on tumor numbers in Min mice. Carcinogenesis. 2002;23:61-65.
27. Lucock M, Yates Z. Folic acid - vitamin and panacea or genetic time bomb? Nat Rev Genet. 2005;6:235-240.
28. Smith AD, Kim Y, Refsum H. Is folic acid good for everyone? Am J Clin Nutr. 2008;87:517-533.
29. Haberg SE, London SJ, Nafstad P, etal. Maternal folate levels in pregnancy and asthma in children at age 3 years. J Allergy Clin Immunol. 2011;127:262-264.
30. 12 in adults. Allergy. 2010;65:1446-1454.
31. Whitrow MJ, Moore VM, Rumbold AR, etal. Effect of supplemental folic acid in pregnancy on childhood asthma: a prospective birth cohort study. Am J Epidemiol. 2009;170:1486-1493.
32. Haberg SE, London SJ, Stigum H, etal. Folic acid supplements in pregnancy and early childhood respiratory health. Arch Dis Child. 2009;94:180-184.
33. Bekkers MB, Elstgeest LE, Scholtens S, etal. Maternal use of folic acid supplements during pregnancy and childhood respiratory health and atopy. Eur Respir J. 2012;39:1468-1474.
34. Dunstan JA, West C, McCarthy S, etal. The relationship between maternal folate status in pregnancy, cord blood folate levels, and allergic outcomes in early childhood. Allergy. 2012;67:50-57.
35. Miyake Y, Sasaki S, Tanaka K, etal. Maternal B vitamin intake during pregnancy and wheeze and eczema in Japanese infants aged 16-24 months: the Osaka Maternal and Child Health Study. Pediatr Allergy Immunol. 2011;22:69-74.
36. Magdelijns FJH, Mommers M, Penders J, etal. Folic acid use in pregnancy and the development of atopy, asthma, and lung function in childhood. Pediatrics. 2011;128:135-144.
37. Kiefte-de Jong J, Timmermans S, Jaddoe VW, etal. High circulating folate and vitamin B-12 concentrations in women during pregnancy are associated with increased prevalence of atopic dermatitis in their offspring. J Nutr. 2012;142:731-738.
38. Martinussen MP, Risnes KR, Jacobsen GW, etal. Folic acid supplementation in early pregnancy and asthma in children aged 6 years. Am J Obstet Gynecol. 2012;206:72.e1-e7.
39. Watanabe H, Fukuoka H, Sugiyama T, etal. Dietary folate intake during pregnancy and birth weight in Japan. Eur J Nutr. 2008;47:341-347.
40. Kim KN, Kim YJ, Chang N. Effects of the interaction between C677T 5, 10-methylenetetrahydrofolate reductase polymorphism and serum B vitamins on homocysteine levels in pregnant women. Eur J Clin Nutr. 2004;58:10-16.
41. Nilsen RM, Vollset SE, Gjsesing HK, etal. Patterns and predictors of folic acid supplement use among pregnant women: the Norwegian Mother and Child Cohort Study. Am J Clin Nutr. 2006;84:1134-1141.