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Volumn 28, Issue 11, 2013, Pages 1469-1478

Expression and localization of axin 2 in colorectal carcinoma and its clinical implication

Author keywords

Catenin; Axin 2; Colorectal carcinoma; Wnt catenin signaling

Indexed keywords

AXIN; AXIN 2; BETA CATENIN; UNCLASSIFIED DRUG;

EID: 84891827961     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-013-1709-6     Document Type: Article
Times cited : (18)

References (48)
  • 3
    • 33847397617 scopus 로고    scopus 로고
    • The canonical Wnt signalling pathway and its APC partner in colon cancer development
    • 16840506 10.1136/gut.2006.093310 1:CAS:528:DC%2BD2sXksVCqs70%3D
    • Schneikert J, Behrens J (2007) The canonical Wnt signalling pathway and its APC partner in colon cancer development. Gut 56(3):417-425
    • (2007) Gut , vol.56 , Issue.3 , pp. 417-425
    • Schneikert, J.1    Behrens, J.2
  • 4
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • 10.1146/annurev.cellbio.20.010403.113126 15473860 10.1146/annurev. cellbio.20.010403.113126 1:CAS:528:DC%2BD2cXhtVejsr7I
    • Logan CY, Nusse R (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20:781-810. doi: 10.1146/annurev.cellbio.20. 010403.113126
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 5
    • 0037344080 scopus 로고    scopus 로고
    • Wnt3a plays a major role in the segmentation clock controlling somitogenesis
    • 12636920 10.1016/S1534-5807(03)00055-8 1:CAS:528:DC%2BD3sXisVekuro%3D
    • Aulehla A, Wehrle C, Brand-Saberi B, Kemler R, Gossler A, Kanzler B, Herrmann BG (2003) Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell 4(3):395-406
    • (2003) Dev Cell , vol.4 , Issue.3 , pp. 395-406
    • Aulehla, A.1    Wehrle, C.2    Brand-Saberi, B.3    Kemler, R.4    Gossler, A.5    Kanzler, B.6    Herrmann, B.G.7
  • 6
    • 80455174708 scopus 로고    scopus 로고
    • Stem cell self-renewal in intestinal crypt
    • 10.1016/j.yexcr.2011.07.010 21787769 10.1016/j.yexcr.2011.07.010 1:CAS:528:DC%2BC3MXhsVaqtrnL
    • Simons BD, Clevers H (2011) Stem cell self-renewal in intestinal crypt. Exp Cell Res 317(19):2719-2724. doi: 10.1016/j.yexcr.2011.07.010
    • (2011) Exp Cell Res , vol.317 , Issue.19 , pp. 2719-2724
    • Simons, B.D.1    Clevers, H.2
  • 7
    • 0034096436 scopus 로고    scopus 로고
    • Stem cells: The intestinal stem cell as a paradigm
    • 10688867 10.1093/carcin/21.3.469 1:CAS:528:DC%2BD3cXitVeisbY%3D
    • Bach SP, Renehan AG, Potten CS (2000) Stem cells: the intestinal stem cell as a paradigm. Carcinogenesis 21(3):469-476
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 469-476
    • Bach, S.P.1    Renehan, A.G.2    Potten, C.S.3
  • 8
    • 47549098136 scopus 로고    scopus 로고
    • The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression
    • 10.1007/s10585-008-9156-4 18350253 10.1007/s10585-008-9156-4 1:CAS:528:DC%2BD1cXhtVeisL7E
    • Vincan E, Barker N (2008) The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression. Clin Exp Metastasis 25(6):657-663. doi: 10.1007/s10585-008-9156-4
    • (2008) Clin Exp Metastasis , vol.25 , Issue.6 , pp. 657-663
    • Vincan, E.1    Barker, N.2
  • 9
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • The Cancer Genome Network 10.1038/nature11252 10.1038/nature11252
    • The Cancer Genome Network (2012) Comprehensive molecular characterization of human colon and rectal cancer. Nature 487(7407):330-337. doi: 10.1038/nature11252
    • (2012) Nature , vol.487 , Issue.7407 , pp. 330-337
  • 10
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • 10.1016/j.ce 22682243 10.1016/j.cell.2012.05.012 1:CAS:528: DC%2BC38XosVaktrg%3D
    • Clevers H, Nusse R (2012) Wnt/beta-catenin signaling and disease. Cell 149(6):1192-1205. doi: 10.1016/j.ce
    • (2012) Cell , vol.149 , Issue.6 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 11
    • 0033971454 scopus 로고    scopus 로고
    • Biochemical interactions in the wnt pathway
    • 10656974 10.1016/S0167-4889(99)00158-5 1:CAS:528:DC%2BD3cXosVKitw%3D%3D
    • Seidensticker MJ, Behrens J (2000) Biochemical interactions in the wnt pathway. Biochim Biophys Acta 1495(2):168-182
    • (2000) Biochim Biophys Acta , vol.1495 , Issue.2 , pp. 168-182
    • Seidensticker, M.J.1    Behrens, J.2
  • 12
    • 0032562603 scopus 로고    scopus 로고
    • Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
    • 9554852 10.1126/science.280.5363.596 1:CAS:528:DyaK1cXjtVahs7o%3D
    • Behrens J, Jerchow BA, Wurtele M, Grimm J, Asbrand C, Wirtz R, Kuhl M, Wedlich D, Birchmeier W (1998) Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 280(5363):596-599
    • (1998) Science , vol.280 , Issue.5363 , pp. 596-599
    • Behrens, J.1    Jerchow, B.A.2    Wurtele, M.3    Grimm, J.4    Asbrand, C.5    Wirtz, R.6    Kuhl, M.7    Wedlich, D.8    Birchmeier, W.9
  • 13
    • 33644967242 scopus 로고    scopus 로고
    • Wnt signaling: Complexity at the surface
    • 16443747 10.1242/jcs.02826 1:CAS:528:DC%2BD28Xit1Klsbw%3D
    • Cadigan KM, Liu YI (2006) Wnt signaling: complexity at the surface. J Cell Sci 119(Pt 3):395-402
    • (2006) J Cell Sci , vol.119 , Issue.PART 3 , pp. 395-402
    • Cadigan, K.M.1    Liu, Y.I.2
  • 14
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
    • 11336703 10.1016/S1097-2765(01)00224-6 1:CAS:528:DC%2BD3MXjsVentL0%3D
    • Mao J, Wang J, Liu B, Pan W, Farr GH, Flynn C 3rd, Yuan H, Takada S, Kimelman D, Li L, Wu D (2001) Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell 7(4):801-809
    • (2001) Mol Cell , vol.7 , Issue.4 , pp. 801-809
    • Mao, J.1    Wang, J.2    Liu, B.3    Pan, W.4    Farr, G.H.5    Flynn III, C.6    Yuan, H.7    Takada, S.8    Kimelman, D.9    Li, L.10    Wu, D.11
  • 15
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • 10.1038/382638a0 8757136 10.1038/382638a0 1:CAS:528:DyaK28XltValtLg%3D
    • Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W (1996) Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382(6592):638-642. doi: 10.1038/382638a0
    • (1996) Nature , vol.382 , Issue.6592 , pp. 638-642
    • Behrens, J.1    Von Kries, J.P.2    Kuhl, M.3    Bruhn, L.4    Wedlich, D.5    Grosschedl, R.6    Birchmeier, W.7
  • 16
    • 0037778008 scopus 로고    scopus 로고
    • The Wnt signaling pathway and its role in tumor development
    • 10.1007/s00432-003-0431-0 12707770 1:STN:280:DC%2BD3s3itFGqtg%3D%3D
    • Lustig B, Behrens J (2003) The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol 129(4):199-221. doi: 10.1007/s00432-003-0431-0
    • (2003) J Cancer Res Clin Oncol , vol.129 , Issue.4 , pp. 199-221
    • Lustig, B.1    Behrens, J.2
  • 17
    • 23844507181 scopus 로고    scopus 로고
    • The role of the Wnt signalling pathway in colorectal tumorigenesis
    • 10.1042/BST0330672 16042571 1:CAS:528:DC%2BD2MXmvFSnu7w%3D
    • Behrens J (2005) The role of the Wnt signalling pathway in colorectal tumorigenesis. Biochem Soc Trans 33(Pt 4):672-675. doi: 10.1042/BST0330672
    • (2005) Biochem Soc Trans , vol.33 , Issue.PART 4 , pp. 672-675
    • Behrens, J.1
  • 18
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • 11809808 10.1128/MCB.22.4.1172-1183.2002 1:CAS:528:DC%2BD38XovVWqtg%3D%3D
    • Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F (2002) Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22(4):1172-1183
    • (2002) Mol Cell Biol , vol.22 , Issue.4 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 20
    • 18944388680 scopus 로고    scopus 로고
    • Mouse axin and axin2/conductin proteins are functionally equivalent in vivo
    • 15899843 10.1128/MCB.25.11.4371-4376.2005 1:CAS:528:DC%2BD2MXkslemtr4%3D
    • Chia IV, Costantini F (2005) Mouse axin and axin2/conductin proteins are functionally equivalent in vivo. Mol Cell Biol 25(11):4371-4376
    • (2005) Mol Cell Biol , vol.25 , Issue.11 , pp. 4371-4376
    • Chia, I.V.1    Costantini, F.2
  • 21
    • 2342613578 scopus 로고    scopus 로고
    • Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer
    • 10.1086/386293 15042511 10.1086/386293 1:CAS:528:DC%2BD2cXjvVeisbw%3D
    • Lammi L, Arte S, Somer M, Jarvinen H, Lahermo P, Thesleff I, Pirinen S, Nieminen P (2004) Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. Am J Hum Genet 74(5):1043-1050. doi: 10.1086/386293
    • (2004) Am J Hum Genet , vol.74 , Issue.5 , pp. 1043-1050
    • Lammi, L.1    Arte, S.2    Somer, M.3    Jarvinen, H.4    Lahermo, P.5    Thesleff, I.6    Pirinen, S.7    Nieminen, P.8
  • 22
    • 77955735139 scopus 로고    scopus 로고
    • Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer
    • 10.1158/0008-5472.CAN-10-1616 20663899 10.1158/0008-5472.CAN-10-1616 1:CAS:528:DC%2BC3cXhtVWqu7bJ
    • Metcalfe C, Ibrahim AE, Graeb M, de la Roche M, Schwarz-Romond T, Fiedler M, Winton DJ, Corfield A, Bienz M (2010) Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. Cancer Res 70(16):6629-6638. doi: 10.1158/0008-5472.CAN-10-1616
    • (2010) Cancer Res , vol.70 , Issue.16 , pp. 6629-6638
    • Metcalfe, C.1    Ibrahim, A.E.2    Graeb, M.3    De La Roche, M.4    Schwarz-Romond, T.5    Fiedler, M.6    Winton, D.J.7    Corfield, A.8    Bienz, M.9
  • 24
    • 65649146135 scopus 로고    scopus 로고
    • The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer
    • 10.1002/cncr.24254 19298008 10.1002/cncr.24254
    • Horst D, Reu S, Kriegl L, Engel J, Kirchner T, Jung A (2009) The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer. Cancer 115(10):2063-2070. doi: 10.1002/cncr.24254
    • (2009) Cancer , vol.115 , Issue.10 , pp. 2063-2070
    • Horst, D.1    Reu, S.2    Kriegl, L.3    Engel, J.4    Kirchner, T.5    Jung, A.6
  • 25
    • 0035964349 scopus 로고    scopus 로고
    • Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
    • 10.1073/pnas.171610498 11526241 10.1073/pnas.171610498 1:CAS:528:DC%2BD3MXmvFWiu7o%3D
    • Brabletz T, Jung A, Reu S, Porzner M, Hlubek F, Kunz-Schughart LA, Knuechel R, Kirchner T (2001) Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci U S A 98(18):10356-10361. doi: 10.1073/pnas.171610498
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.18 , pp. 10356-10361
    • Brabletz, T.1    Jung, A.2    Reu, S.3    Porzner, M.4    Hlubek, F.5    Kunz-Schughart, L.A.6    Knuechel, R.7    Kirchner, T.8
  • 26
    • 34648813274 scopus 로고    scopus 로고
    • Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer
    • 10.1002/ijc.22916 17631641 10.1002/ijc.22916 1:CAS:528: DC%2BD2sXhtFSjsL%2FM
    • Hlubek F, Brabletz T, Budczies J, Pfeiffer S, Jung A, Kirchner T (2007) Heterogeneous expression of Wnt/beta-catenin target genes within colorectal cancer. Int J Cancer 121(9):1941-1948. doi: 10.1002/ijc.22916
    • (2007) Int J Cancer , vol.121 , Issue.9 , pp. 1941-1948
    • Hlubek, F.1    Brabletz, T.2    Budczies, J.3    Pfeiffer, S.4    Jung, A.5    Kirchner, T.6
  • 28
    • 0031727409 scopus 로고    scopus 로고
    • Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front
    • 9820866 10.1016/S0344-0338(98)80129-5 1:CAS:528:DyaK1cXmvV2ntL0%3D
    • Brabletz T, Jung A, Hermann K, Gunther K, Hohenberger W, Kirchner T (1998) Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. Pathol Res Pract 194(10):701-704
    • (1998) Pathol Res Pract , vol.194 , Issue.10 , pp. 701-704
    • Brabletz, T.1    Jung, A.2    Hermann, K.3    Gunther, K.4    Hohenberger, W.5    Kirchner, T.6
  • 29
    • 84863230264 scopus 로고    scopus 로고
    • Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling
    • 10.1158/0008-5472 22318865 10.1158/0008-5472.CAN-11-3222 1:CAS:528:DC%2BC38XktVanu7s%3D
    • Horst D, Chen J, Morikawa T, Ogino S, Kirchner T, Shivdasani RA (2012) Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling. Cancer Res 72(6):1547-1556. doi: 10.1158/0008-5472
    • (2012) Cancer Res , vol.72 , Issue.6 , pp. 1547-1556
    • Horst, D.1    Chen, J.2    Morikawa, T.3    Ogino, S.4    Kirchner, T.5    Shivdasani, R.A.6
  • 30
    • 84891834478 scopus 로고    scopus 로고
    • Wiley Edition. 6th Uicc (2002) (eds) W.C
    • Sobin LH, Wittekind C (eds) (2002) UICC 6th edition. Wiley
    • Sobin, L.H.1
  • 32
    • 0036841930 scopus 로고    scopus 로고
    • Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases
    • 10.1016/S0002-9440(10)64452-5 12414522 10.1016/S0002-9440(10)64452-5 1:CAS:528:DC%2BD38XptV2gtLs%3D
    • Lubeseder-Martellato C, Guenzi E, Jörg A, Töpolt K, Naschberger E, Kremmer E, Zietz C, Tschachler E, Hutzler P, Schwemmle M, Matzen K, Grimm T, Ensoli B, Stürzl M (2002) Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol 161(5):1749-1759. doi: 10.1016/S0002-9440(10)64452-5
    • (2002) Am J Pathol , vol.161 , Issue.5 , pp. 1749-1759
    • Lubeseder-Martellato, C.1    Guenzi, E.2    Jörg, A.3    Töpolt, K.4    Naschberger, E.5    Kremmer, E.6    Zietz, C.7    Tschachler, E.8    Hutzler, P.9    Schwemmle, M.10    Matzen, K.11    Grimm, T.12    Ensoli, B.13    Stürzl, M.14
  • 34
    • 0026780550 scopus 로고
    • Expression of platelet-derived growth factor and its receptor in AIDS-related Kaposi sarcoma in vivo suggests paracrine and autocrine mechanisms of tumor maintenance
    • 1323124 10.1073/pnas.89.15.7046
    • Stürzl M, Roth WK, Brockmeyer NH, Zietz C, Speiser B, Hofschneider PH (1992) Expression of platelet-derived growth factor and its receptor in AIDS-related Kaposi sarcoma in vivo suggests paracrine and autocrine mechanisms of tumor maintenance. Proc Natl Acad Sci U S A 89(15):7046-7050
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.15 , pp. 7046-7050
    • Stürzl, M.1    Roth, W.K.2    Brockmeyer, N.H.3    Zietz, C.4    Speiser, B.5    Hofschneider, P.H.6
  • 35
    • 57349108800 scopus 로고    scopus 로고
    • Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression
    • Weinländer K, Naschberger E, Lehmann MH, Tripal P, Paster W, Stockinger H, Hohenadl C, Stürzl M (2008) Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression. Faseb J 22 (12):4168-4178
    • (2008) Faseb J , vol.22 , Issue.12 , pp. 4168-4178
    • Weinländer, K.N.1
  • 36
    • 69549108768 scopus 로고    scopus 로고
    • RNA extraction from archival formalin-fixed paraffin-embedded tissue: A comparison of manual, semiautomated, and fully automated purification methods
    • 10.1373/clinchem.2008.122572 19617290 10.1373/clinchem.2008.122572 1:CAS:528:DC%2BD1MXhtVynt77E
    • Bohmann K, Hennig G, Rogel U, Poremba C, Mueller BM, Fritz P, Stoerkel S, Schaefer KL (2009) RNA extraction from archival formalin-fixed paraffin-embedded tissue: a comparison of manual, semiautomated, and fully automated purification methods. Clin Chem 55(9):1719-1727. doi: 10.1373/clinchem.2008.122572
    • (2009) Clin Chem , vol.55 , Issue.9 , pp. 1719-1727
    • Bohmann, K.1    Hennig, G.2    Rogel, U.3    Poremba, C.4    Mueller, B.M.5    Fritz, P.6    Stoerkel, S.7    Schaefer, K.L.8
  • 39
    • 79952167236 scopus 로고    scopus 로고
    • Quantitative determination of estrogen receptor, progesterone receptor, and HER2 mRNA in formalin-fixed paraffin-embedded tissue - A new option for predictive biomarker assessment in breast cancer
    • 10.1097/PDM.0b013e3181e3630c 21326033 10.1097/PDM.0b013e3181e3630c
    • Müller BM, Kronenwett R, Hennig G, Euting H, Weber K, Bohmann K, Weichert W, Altmann G, Roth C, Winzer KJ, Kristiansen G, Petry C, Dietel M, Denkert C (2011) Quantitative determination of estrogen receptor, progesterone receptor, and HER2 mRNA in formalin-fixed paraffin-embedded tissue - a new option for predictive biomarker assessment in breast cancer. Diagn Mol Pathol 20(1):1-10. doi: 10.1097/PDM.0b013e3181e3630c
    • (2011) Diagn Mol Pathol , vol.20 , Issue.1 , pp. 1-10
    • Müller, B.M.1    Kronenwett, R.2    Hennig, G.3    Euting, H.4    Weber, K.5    Bohmann, K.6    Weichert, W.7    Altmann, G.8    Roth, C.9    Winzer, K.J.10    Kristiansen, G.11    Petry, C.12    Dietel, M.13    Denkert, C.14
  • 40
    • 0035710433 scopus 로고    scopus 로고
    • Real-time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded biopsies
    • 10.1006/meth.2001.1263 11846610 10.1006/meth.2001.1263 1:CAS:528:DC%2BD38XhtFelt7g%3D
    • Lehmann U, Kreipe H (2001) Real-time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded biopsies. Methods 25(4):409-418. doi: 10.1006/meth.2001.1263
    • (2001) Methods , vol.25 , Issue.4 , pp. 409-418
    • Lehmann, U.1    Kreipe, H.2
  • 42
    • 1242272084 scopus 로고    scopus 로고
    • Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway
    • 10.1074/jbc.M307253200 14630927 10.1074/jbc.M307253200 1:CAS:528:DC%2BD2cXhtFeqtro%3D
    • Wiechens N, Heinle K, Englmeier L, Schohl A, Fagotto F (2004) Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway. J Biol Chem 279(7):5263-5267. doi: 10.1074/jbc.M307253200
    • (2004) J Biol Chem , vol.279 , Issue.7 , pp. 5263-5267
    • Wiechens, N.1    Heinle, K.2    Englmeier, L.3    Schohl, A.4    Fagotto, F.5
  • 44
    • 33646583259 scopus 로고    scopus 로고
    • Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention
    • 10.1242/jcs.02864 12 16554443 10.1242/jcs.02864 1:CAS:528: DC%2BD28Xks1Wjtb0%3D
    • Krieghoff E, Behrens J, Mayr B (2006) Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention. J Cell Sci 119(Pt 7):1453-1463. doi: 10.1242/jcs.02864 12
    • (2006) J Cell Sci , vol.119 , Issue.PART 7 , pp. 1453-1463
    • Krieghoff, E.1    Behrens, J.2    Mayr, B.3
  • 45
    • 77950368590 scopus 로고    scopus 로고
    • Conductin/axin2 and Wnt signalling regulates centrosome cohesion
    • 10.1038/embor.2010.23 20300119 10.1038/embor.2010.23 1:CAS:528: DC%2BC3cXjsFWjsbs%3D
    • Hadjihannas MV, Bruckner M, Behrens J (2010) Conductin/axin2 and Wnt signalling regulates centrosome cohesion. EMBO Rep 11(4):317-324. doi: 10.1038/embor.2010.23
    • (2010) EMBO Rep , vol.11 , Issue.4 , pp. 317-324
    • Hadjihannas, M.V.1    Bruckner, M.2    Behrens, J.3
  • 46
    • 33746096996 scopus 로고    scopus 로고
    • Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer
    • 10.1073/pnas.0604206103 16815967 10.1073/pnas.0604206103 1:CAS:528:DC%2BD28XntFWmsbs%3D
    • Hadjihannas MV, Bruckner M, Jerchow B, Birchmeier W, Dietmaier W, Behrens J (2006) Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer. Proc Natl Acad Sci U S A 103(28):10747-10752. doi: 10.1073/pnas.0604206103
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.28 , pp. 10747-10752
    • Hadjihannas, M.V.1    Bruckner, M.2    Jerchow, B.3    Birchmeier, W.4    Dietmaier, W.5    Behrens, J.6
  • 47
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • 10.1038/386623a0 9121588 10.1038/386623a0 1:CAS:528:DyaK2sXisFCntrk%3D
    • Lengauer C, Kinzler KW, Vogelstein B (1997) Genetic instability in colorectal cancers. Nature 386(6625):623-627. doi: 10.1038/386623a0
    • (1997) Nature , vol.386 , Issue.6625 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.