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Volumn 37, Issue 1, 2014, Pages 43-49

Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway

Author keywords

hypertensive myocardial remodeling; myocardial fibrosis; telmisartan; TGF 1 Smad

Indexed keywords

ALDOSTERONE; ANGIOTENSIN II; COLLAGEN FIBER; MATRIX METALLOPROTEINASE; SMAD PROTEIN; TELMISARTAN; TISSUE INHIBITOR OF METALLOPROTEINASE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84891807068     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2013.119     Document Type: Article
Times cited : (44)

References (26)
  • 2
    • 33745280899 scopus 로고    scopus 로고
    • Alterations in the Pattern of Collagen Deposition May Contribute to the Deterioration of Systolic Function in Hypertensive Patients With Heart Failure
    • DOI 10.1016/j.jacc.2006.01.077, PII S0735109706009065
    • López B, González A, Querejeta R, Larman M, Díez J. Alterations in the pattern of collagen deposition may contribute to the deterioration of systolic function in hypertensive patients with heart failure. J Am Coll Cardiol 2006; 48: 89-96. (Pubitemid 43929208)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.1 , pp. 89-96
    • Lopez, B.1    Gonzalez, A.2    Querejeta, R.3    Larman, M.4    Diez, J.5
  • 3
    • 21644466165 scopus 로고    scopus 로고
    • Negative regulation of TGF-β signaling in development
    • DOI 10.1038/sj.cr.7290246
    • Chen YG, Meng AM. Negative regulation of TGF-beta signaling in development. Cell Res 2004; 14: 441-449. (Pubitemid 43231788)
    • (2004) Cell Research , vol.14 , Issue.6 , pp. 441-449
    • Chen, Y.G.1    Meng, A.M.2
  • 4
    • 33646562542 scopus 로고    scopus 로고
    • The logic of TGF beta signaling
    • Massague J, Gomis RR. The logic of TGF beta signaling. FEBS Lett 2006; 580: 2811-2820.
    • (2006) FEBS Lett , vol.580 , pp. 2811-2820
    • Massague, J.1    Gomis, R.R.2
  • 5
    • 34248661541 scopus 로고    scopus 로고
    • Redox-sensitive myocardial remodeling and dysfunction in swine diet-induced experimental hypercholesterolemia
    • DOI 10.1016/j.atherosclerosis.2006.08.035, PII S0021915006004862
    • Zhu XY, Daghini E, Rodriguez-Porcel M, Chade AR, Napoli C, Lerman A, Lerman LO. Redox-sensitive myocardial remodeling and dysfunction in swine diet-induced experimental hypercholesterolemia. Atherosclerosis 2007; 193: 62-69. (Pubitemid 46776711)
    • (2007) Atherosclerosis , vol.193 , Issue.1 , pp. 62-69
    • Zhu, X.-Y.1    Daghini, E.2    Rodriguez-Porcel, M.3    Chade, A.R.4    Napoli, C.5    Lerman, A.6    Lerman, L.O.7
  • 6
    • 64649102284 scopus 로고    scopus 로고
    • Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload
    • Xia Y, Lee K, Li N, Corbett D, Mendoza L, Frangogiannis NG. Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem Cell Biol 2009; 131: 471-481.
    • (2009) Histochem Cell Biol , vol.131 , pp. 471-481
    • Xia, Y.1    Lee, K.2    Li, N.3    Corbett, D.4    Mendoza, L.5    Frangogiannis, N.G.6
  • 7
    • 0037465434 scopus 로고    scopus 로고
    • Progression from compensated hypertrophy to failure in the pressure-overloaded human: Heart structural deterioration and compensatory mechanisms
    • DOI 10.1161/01.CIR.0000051865.66123.B7
    • Hein S, Arnon E, Kostin S, Schönburg M, Elsässer A, Polyakova V, Bauer EP, Klövekorn WP, Schaper J. Progression from compensated hypertrophy to failure in the pressure-overloaded human heart-structural deterioration and compensatory mechanisms. Circulation 2003; 107: 984-991. (Pubitemid 36258721)
    • (2003) Circulation , vol.107 , Issue.7 , pp. 984-991
    • Hein, S.1    Arnon, E.2    Kostin, S.3    Schonburg, M.4    Elsasser, A.5    Polyakova, V.6    Bauer, E.P.7    Klovekorn, W.-P.8    Schaper, J.9
  • 9
    • 2942571336 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-β1 involves furin-convertase
    • DOI 10.1016/j.cardiores.2004.03.010, PII S0008636304001269
    • Stawowy P, Margeta C, Kallisch H, Seidah NG, Chrétien M, Fleck E, Graf K. Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-beta 1 involves furin-convertase. Cardiovasc Res 2004; 63: 87-97. (Pubitemid 38759813)
    • (2004) Cardiovascular Research , vol.63 , Issue.1 , pp. 87-97
    • Stawowy, P.1    Margeta, C.2    Kallisch, H.3    Seidah, N.G.4    Chretien, M.5    Fleck, E.6    Graf, K.7
  • 10
    • 34548414571 scopus 로고    scopus 로고
    • Myocardial fibrosis and diastolic dysfunction in patients with hypertension: Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)
    • DOI 10.1097/HJH.0b013e3282170ada, PII 0000487220070900000028
    • Mü ller-Brunotte R, Kahan T, López B, Edner M, González A, Díez J, Malmqvist K. Myocardial fibrosis and diastolic dysfunction in patients with hypertension: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA). J Hypertens 2007; 25: 1958-1966. (Pubitemid 47356638)
    • (2007) Journal of Hypertension , vol.25 , Issue.9 , pp. 1958-1966
    • Muller-Brunotte, R.1    Kahan, T.2    Lopez, B.3    Edner, M.4    Gonzalez, A.5    Diez, J.6    Malmqvist, K.7
  • 11
    • 3543086880 scopus 로고    scopus 로고
    • Different effects of antihypertensive therapies based on losartan or atenolol on ultrasound and biochemical markers of myocardial fibrosis: Results of a randomized trial
    • DOI 10.1161/01.CIR.0000137118.47943.5C
    • Ciulla MM, Paliotti R, Esposito A, D?̀ez J, López B, Dahlöf B, Nicholls MG, Smith RD, Gilles L, Magrini F, Zanchetti A. Different effects of antihypertensive therapies based on losartan or atenolol on ultrasound and biochemical markers of myocardial fibrosis-results of a randomized trial. Circulation 2004; 110: 552-557. (Pubitemid 39031172)
    • (2004) Circulation , vol.110 , Issue.5 , pp. 552-557
    • Ciulla, M.M.1    Paliotti, R.2    Esposito, A.3    Diez, J.4    Lopez, B.5    Dahlof, B.6    Nicholls, M.G.7    Smith, R.D.8    Gilles, L.9    Magrini, F.10    Zanchetti, A.11
  • 12
    • 34047137843 scopus 로고    scopus 로고
    • Role of activated renin-angiotensin system myocardial fibrosis and left ventricular diastolic dysfunction in diabetic patients - Reversal by chronic angiotensin II type 1A receptor blockade
    • DOI 10.1253/circj.71.524
    • Kawasaki D, Kosugi K, Waki H, Yamamoto K, Tsujino T, Masuyama T. Role of activated renin-angiotensin system in myocardial fibrosis and left ventricular diastolic dysfunction in diabetic patients-reversal by chronic angiotensin II type 1A receptor blockade. Circ J 2007; 71: 524-529. (Pubitemid 46513459)
    • (2007) Circulation Journal , vol.71 , Issue.4 , pp. 524-529
    • Kawasaki, D.1    Kosugi, K.2    Waki, H.3    Yamamoto, K.4    Tsujino, T.5    Masuyama, T.6
  • 13
    • 25644435620 scopus 로고    scopus 로고
    • Valsartan decreases type I collagen synthesis in patients with hypertrophic cardiomyopathy
    • DOI 10.1253/circj.69.1244
    • Kawano H, Toda G, Nakamizo R, Koide Y, Seto S, Yano K. Valsartan decreases type I collagen synthesis in patients with hypertrophic cardiomyopathy. Circ J 2005; 69: 1244-1248. (Pubitemid 41382947)
    • (2005) Circulation Journal , vol.69 , Issue.10 , pp. 1244-1248
    • Kawano, H.1    Toda, G.2    Nakamizo, R.3    Koide, Y.4    Seto, S.5    Yano, K.6
  • 14
    • 38049170536 scopus 로고    scopus 로고
    • Management of hypertension in patients with left ventricular hypertroph
    • Cuspidi C, Sala C, Zanchetti A. Management of hypertension in patients with left ventricular hypertroph. Curr Hypertens Rep 2007; 9: 498-505.
    • (2007) Curr Hypertens Rep , vol.9 , pp. 498-505
    • Cuspidi, C.1    Sala, C.2    Zanchetti, A.3
  • 15
    • 66549112420 scopus 로고    scopus 로고
    • Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study
    • Iraqi W, Rossignol P, Angioi M, Fay R, Nuée J, Ketelslegers JM, Vincent J, Pitt B, Zannad F. Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) Study. Circulation 2009; 119: 2471-2479.
    • (2009) Circulation , vol.119 , pp. 2471-2479
    • Iraqi, W.1    Rossignol, P.2    Angioi, M.3    Fay, R.4    Nuée, J.5    Ketelslegers, J.M.6    Vincent, J.7    Pitt, B.8    Zannad, F.9
  • 16
    • 53149102406 scopus 로고    scopus 로고
    • Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats
    • Zhao W, Zhao T, Chen Y, Ahokas RA, Sun Y. Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats. Mol Cell Biochem 2008; 317: 43-50.
    • (2008) Mol Cell Biochem , vol.317 , pp. 43-50
    • Zhao, W.1    Zhao, T.2    Chen, Y.3    Ahokas, R.A.4    Sun, Y.5
  • 17
    • 0035914339 scopus 로고    scopus 로고
    • Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3
    • Yuan WH, Varga J. Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. J Biol Chem 2001; 276: 38502-38510.
    • (2001) J Biol Chem , vol.276 , pp. 38502-38510
    • Yuan, W.H.1    Varga, J.2
  • 18
    • 41149122223 scopus 로고    scopus 로고
    • Atrial natriuretic peptide inhibits transforming growth factor β-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts
    • DOI 10.1161/CIRCRESAHA.107.157677
    • Li P, Wang D, Lucas J, Oparil S, Xing D, Cao X, Novak L, Renfrow MB, Chen YF. Atrial natriuretic peptide inhibits transforming growth factor beta-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts. Circ Res 2008; 102: 185-192. (Pubitemid 351651122)
    • (2008) Circulation Research , vol.102 , Issue.2 , pp. 185-192
    • Li, P.1    Wang, D.2    Lucas, J.3    Oparil, S.4    Xing, D.5    Cao, X.6    Novak, L.7    Renfrow, M.B.8    Chen, Y.-F.9
  • 19
    • 31944442876 scopus 로고    scopus 로고
    • The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophy
    • DOI 10.116110.1161/01.HYP.0000193504.51489.cf
    • D'Amore A, Black MJ, Thomas WG. The angiotensin II type 2 receptor causes constitutive growth of cardiomyocytes and does not antagonize angiotensin II type 1 receptor-mediated hypertrophy. Hypertension 2005; 46: 1347-1354. (Pubitemid 43189734)
    • (2005) Hypertension , vol.46 , Issue.6 , pp. 1347-1354
    • D'Amore, A.1    Black, M.J.2    Thomas, W.G.3
  • 20
    • 0041885281 scopus 로고    scopus 로고
    • Hypertension, matrix metalloproteinases and target organ damage
    • DOI 10.1097/00004872-200309000-00009
    • Donnelly R, Collinson DJ, Manning G. Hypertension, matrix metalloproteinases and target organ damage. J Hypertens 2003; 21: 1627-1630. (Pubitemid 37076343)
    • (2003) Journal of Hypertension , vol.21 , Issue.9 , pp. 1627-1630
    • Donnelly, R.1    Collinson, D.J.2    Manning, G.3
  • 21
    • 33645806742 scopus 로고    scopus 로고
    • Fibrosis in heart disease: Understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia
    • Khan R, Sheppard R. Fibrosis in heart disease: understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia. Immunology 2006; 118: 10-24.
    • (2006) Immunology , vol.118 , pp. 10-24
    • Khan, R.1    Sheppard, R.2
  • 22
    • 70350462126 scopus 로고    scopus 로고
    • Reduced phosphorylation of the TGF-Beta signal transducer Smad2 in emphysematous human lung
    • Leppäranta O, Myllärniemi M, Salmenkivi K, Kinnula VL, Keski-Oja J, Koli K. Reduced phosphorylation of the TGF-Beta signal transducer Smad2 in emphysematous human lung. COPD 2009; 6: 234-241.
    • (2009) COPD , vol.6 , pp. 234-241
    • Leppäranta, O.1    Myllärniemi, M.2    Salmenkivi, K.3    Kinnula, V.L.4    Keski-Oja, J.5    Koli, K.6
  • 23
    • 78651363548 scopus 로고    scopus 로고
    • Angiotensin II receptors and drug discovery in cardiovascular disease
    • Dasgupta C, Zhang L. Angiotensin II receptors and drug discovery in cardiovascular disease. Drug Discov Today 2011; 16: 22-34.
    • (2011) Drug Discov Today , vol.16 , pp. 22-34
    • Dasgupta, C.1    Zhang, L.2
  • 25
    • 77957554153 scopus 로고    scopus 로고
    • Effects of captopril and telmisartan on matrix metalloproteinase-2 and-9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats
    • Okada M, Kosaka N, Hoshino Y, Yamawaki H, Hara Y. Effects of captopril and telmisartan on matrix metalloproteinase-2 and-9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biol Pharm Bull 2010; 33: 1517-1521.
    • (2010) Biol Pharm Bull , vol.33 , pp. 1517-1521
    • Okada, M.1    Kosaka, N.2    Hoshino, Y.3    Yamawaki, H.4    Hara, Y.5
  • 26
    • 55949135607 scopus 로고    scopus 로고
    • Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats
    • Liang B, Leenen FH. Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats. J Cardiovasc Pharmacol 2008; 51: 457-466.
    • (2008) J Cardiovasc Pharmacol , vol.51 , pp. 457-466
    • Liang, B.1    Leenen, F.H.2


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