Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress

Cell Death and Disease

Volumn 5, Issue 1, 2014, Pages

  Doti, N ^a,b,c   Reuther, C ^b   Scognamiglio, P L ^a   Dolga, A M ^b   Plesnila, N ^c,d   Ruvo, M ^a   Culmsee, C ^b  

^a CNR   (Italy)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

AIF CypA complex; Mitochondria; Neuronal death; Oxidative stress; Peptide inhibitor

Indexed keywords

APOPTOSIS INDUCING FACTOR; CALCIUM ION; CYCLOPHILIN A; GLUTAMIC ACID; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; IN VITRO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NERVE CELL NECROSIS; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TRANSPORT;

AMINO ACID MOTIFS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CYCLOPHILIN A; DOWN-REGULATION; HUMANS; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; PROTEIN BINDING;

EID: 84891783666     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.518     Document Type: Article

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