Nelfinavir Inhibits Intra-Mitochondrial Calcium Influx and Protects Brain against Hypoxic-Ischemic Injury in Neonatal Mice

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Utkina Sosunova, Irina V ^a   Niatsetskaya, Zoya V ^a   Sosunov, Sergey A ^a   Ratner, Veniamin I ^a   Matsiukevich, Dzmitry ^a   Ten, Vadim S ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE DIPHOSPHATE; CALCIUM ION; CYTOCHROME C; GLUCOSE; HISTAMINE; MEMBRANE PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NELFINAVIR; OXYGEN; RUTHENIUM RED; UNCLASSIFIED DRUG; UNIPORTER; CALCIUM; CALCIUM CHANNEL; CARRIER PROTEIN; MITOCHONDRIAL CALCIUM UNIPORTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN PROTECTION; CALCIUM TRANSPORT; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM; HIPPOCAMPUS; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEWBORN; NONHUMAN; PHOSPHORYLATION; PROTEIN SECRETION; REPERFUSION; ANIMAL; BRAIN; C57BL MOUSE; DRUG EFFECTS; HYPOXIA-ISCHEMIA, BRAIN; METABOLISM; MITOCHONDRION; PATHOLOGY; REPERFUSION INJURY; SECRETION (PROCESS);

MURINAE; MUS; RODENTIA;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CALCIUM; CALCIUM CHANNELS; CYTOCHROMES C; HYPOXIA-ISCHEMIA, BRAIN; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; NELFINAVIR; PHOSPHORYLATION; REPERFUSION INJURY; RUTHENIUM RED;

EID: 84876429613     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0062448     Document Type: Article

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