Persistent telomere cohesion triggers a prolonged anaphase

Molecular Biology of the Cell

Volumn 25, Issue 1, 2014, Pages 30-40

  Kim, Mi Kyung ^a   Smith, Susan ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COHESIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TANKYRASE; TANKYRASE 1; UNCLASSIFIED DRUG;

ANAPHASE; ARTICLE; CANCER CELL; CELL AGING; CELL LINE; CHROMOSOME; CONTROLLED STUDY; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOSIS; MITOSIS INHIBITION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; SISTER CHROMATID; TELOMERE;

ANAPHASE; CELL ADHESION MOLECULES; CELL AGING; FIBROBLASTS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; NUCLEAR PROTEINS; RNA, SMALL INTERFERING; TANKYRASES; TELOMERE; TELOMERE HOMEOSTASIS;

EID: 84891776770     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E13-08-0479     Document Type: Article

References (33)

1. Anderson DE, Losada A, Erickson HP, Hirano T (2002). Condensin and cohesin display different arm conformations with characteristic hinge angles. J Cell Biol 156, 419-424.
2. Bisht KK, Daniloski Z, Smith S (2013). SA1 binds directly to DNA via its unique AT-hook to promote sister chromatid cohesion at telomeres. J Cell Sci 126, 3493-503.
3. Bisht KK, Dudognon C, Chang WG, Sokol ES, Ramirez A, Smith S (2012). GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity. Mol Cell Biol 32, 3044-3053.
4. Canudas S, Houghtaling BR, Bhanot M, Sasa G, Savage SA, Bertuch AA, Smith S (2011). A role for heterochromatin protein 1{gamma} at human telomeres. Genes Dev 25, 1807-1819.
5. Canudas S, Houghtaling BR, Kim JY, Dynek JN, Chang WG, Smith S (2007). Protein requirements for sister telomere association in human cells. EMBO J 26, 4867-4878.
6. Canudas S, Smith S (2009). Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells. J Cell Biol 187, 165-173.
7. Chang P, Coughlin M, Mitchison TJ (2005). Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol 7, 1133-1139.
8. Dynek JN, Smith S (2004). Resolution of sister telomere association is required for progression through mitosis. Science 304, 97-100.
9. d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP (2003). A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194-198.
10. D'Amours D, Stegmeier F, Amon A (2004). Cdc14 and condensin control the dissolution of cohesin-independent chromosome linkages at repeated DNA. Cell 117, 455-469.
11. Fumagalli M et al. (2012). Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat Cell Biol 14, 355-365.
12. Haering CH, Lowe J, Hochwagen A, Nasmyth K (2002). Molecular architecture of SMC proteins and the yeast cohesin complex. Mol Cell 9, 773-788.
13. Hauf S, Roitinger E, Koch B, Dittrich CM, Mechtler K, Peters JM (2005). Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 3, e69.
14. Hauf S, Waizenegger IC, Peters JM (2001). Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science 293, 1320-1323.
15. Houghtaling BR, Cuttonaro L, Chang W, Smith S (2004). A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr Biol 14, 1621-1631.
16. Hsiao SJ, Smith S (2008). Tankyrase function at telomeres, spindle poles, and beyond. Biochimie 90, 83-92.
17. Hsiao SJ, Smith S (2009). Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ. J Cell Biol 184, 515-526.
18. Huang SM et al. (2009). Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614-620.
19. Kanda T, Sullivan KF, Wahl GM (1998). Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells. Curr Biol 8, 377-385.
20. Losada A, Yokochi T, Kobayashi R, Hirano T (2000). Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes. J Cell Biol 150, 405-416.
21. Lyons NA, Morgan DO (2011). Cdk1-dependent destruction of Eco1 prevents cohesion establishment after S phase. Mol Cell 42, 378-389.
22. Ofir R, Yalon-Hacohen M, Segev Y, Schultz A, Skorecki KL, Selig S (2002). Replication and/or separation of some human telomeres is delayed beyond S-phase in pre-senescent cells. Chromosoma 111, 147-155.
23. Palm W, de Lange T (2008). How shelterin protects mammalian telomeres. Annu Rev Genet 42, 301-334.
24. Remeseiro S, Cuadrado A, Carretero M, Martinez P, Drosopoulos WC, Canamero M, Schildkraut CL, Blasco MA, Losada A (2012). Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. EMBO J 31, 2076-2089.
25. Scherthan H, Jerratsch M, Li B, Smith S, Hulten M, Lock T, de Lange T (2000). Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores. Mol Biol Cell 11, 4189-4203.
26. Smith S, Giriat I, Schmitt A, de Lange T (1998). Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282, 1484-1487.
27. Sullivan M, Higuchi T, Katis VL, Uhlmann F (2004). Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase. Cell 117, 471-482.
28. Sumara I, Vorlaufer E, Gieffers C, Peters BH, Peters JM (2000). Characterization of vertebrate cohesin complexes and their regulation in prophase. J Cell Biol 151, 749-762.
29. Tanaka T, Fuchs J, Loidl J, Nasmyth K (2000). Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nat Cell Biol 2, 492-499.
30. van Steensel B, de Lange T (1997). Control of telomere length by the human telomeric protein TRF1. Nature 385, 740-743.
31. van Steensel B, Smogorzewska A, de Lange T (1998). TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413.
32. Waizenegger IC, Hauf S, Meinke A, Peters JM (2000). Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell 103, 399-410.
33. Yalon M, Gal S, Segev Y, Selig S, Skorecki KL (2004). Sister chromatid separation at human telomeric regions. J Cell Sci 117, 1961-1970.