Calcium alginate particles for the combined delivery of platelet lysate and vancomycin hydrochloride in chronic skin ulcers

International Journal of Pharmaceutics

Volumn 461, Issue 1-2, 2014, Pages 505-513

  Mori, Michela ^a   Rossi, Silvia ^a   Bonferoni, Maria Cristina ^a   Ferrari, Franca ^a   Sandri, Giuseppina ^a   Riva, Federica ^a   Del Fante, Claudia ^b   Perotti, Cesare ^b   Caramella, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b Immunohaematology and Transfusion Service and Cell Therapy Unit of Fondazione IRCCS S Matteo   (Italy)

Author keywords

Freeze dried beads; Platelet lysate; Skin ulcers; Vancomycin hydrochloride; Wound healing

Indexed keywords

CALCIUM ALGINATE; PLATELET DERIVED GROWTH FACTOR AB; VANCOMYCIN; ALGINIC ACID; ANTIINFECTIVE AGENT; GEL; GLUCURONIC ACID; HEXURONIC ACID; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR AB;

ARTICLE; CELL DENSITY; CELL LYSATE; CELL PROLIFERATION; CELL VIABILITY; CHRONIC DISEASE; CHRONIC WOUND; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG FORMULATION; DRUG RELEASE; FIBROBLAST; FREEZE DRYING; GAUZE DRESSING; GELATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; SKIN ULCER; THROMBOCYTE; VISCOSITY; WOUND FLUID; WOUND HEALING; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; GEL; MEDICINAL CHEMISTRY; METABOLISM; PATHOLOGY; PROCEDURES;

ALGINATES; ANTI-BACTERIAL AGENTS; BLOOD PLATELETS; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; FREEZE DRYING; GELS; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; PLATELET-DERIVED GROWTH FACTOR; SKIN ULCER; VANCOMYCIN; WOUND HEALING;

EID: 84891765105     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.12.020     Document Type: Article

References (20)

1. E. Anitua, M. Sanchez, G. Orive, and I. Andia The potential impact of the preparation rich in growth factors (PRGF) in different medical fields Biomaterials 28 2007 4551 4560 (Pubitemid 47271893)
2. J.S. Boateng, K.H. Matthews, N.E.S. Howard, and G.M. Eccleston Wound healing dressing and drug delivery system: a review J. Pharm. Sci. 97 2008 2892 2923
3. P. Borzini, and L. Mazzucco Platelet gels and releasates Curr. Opin. Hematol. 12 2005 473 479 (Pubitemid 41546479)
4. C.M. Caramella, G. Sandri, S. Rossi, M. Mori, M.C. Bonferoni, F. Ferrari, C. Del Fante, and C. Perotti New therapeutic platforms for the treatment of epithelial and cutaneous lesions Curr. Drug Deliv. 10 2013 18 31
5. G. Crovetti, G. Martinelli, M. Issi, M. Barone, M. Guizzardi, B. Campanati, M. Moroni, and A. Carabelli Platelet gel for healing cutaneous chronic wounds Transfus. Apheresis Sci. 30 2004 145 151 (Pubitemid 38519799)
6. P.N. Dean, F. Dolbeare, H. Gratzner, G.C. Rice, and J.W. Gray Cell-cycle analysis using a monoclonal antibody to BrdUrd Cell Tissue Kinet. 17 1984 427 436 (Pubitemid 14051025)
7. C. Del Fante, C. Perotti, M.C. Bonferoni, S. Rossi, G. Sandri, F. Ferrari, L. Scudeller, and C.M. Caramella Platelet lysate mucohadesive formulation to treat oral mucositis in graft versus host disease patients: a new therapeutic approach AAPS PharmSciTech 12 2011 893 899
8. T.G. Denis, T. Dai, Y.-Y. Huang, and M.R. Hambling Wound-healing properties of chitosan and its use in wound dressings biopharmaceuticals B. Sarmento, J. das Neves, Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics 2012 John Wiley & Sons, Ltd. Chichester 281 304
9. D.M. Dohan Ehrenfest, and L.T. Rasmusson Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to Albrektsson leucocyte- and platelet rich fibrin (L-PRF) Trends Biotechnol. 27 2009 158 167
10. P.A. Hall, and D.A. Levison Review: assessment of cell proliferation in histological material J. Clin. Pathol. 43 1990 184 192 (Pubitemid 20087565)
11. L. Mazzucco, D. Medici, M. Serra, R. Panizza, G. Rivara, S. Orecchia, R. Libener, E. Cattana, A. Levis, P.G. Betta, and P. Borzini The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study Transfusion 44 2004 1013 1018 (Pubitemid 38823807)
12. Y. Ogino, Y. Ayukawa, and T. Kukita The contribution of platelet-derived growth factor, transforming growth factor-β1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblast-like cells Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol. 101 2006 724 729 (Pubitemid 43775450)
13. E. Ranzato, M. Patrone, L. Mazzucco, and B. Burlando Platelet lysate stimulates wound repair of HaCaT keratinocytes Br. J. Dermatol. 159 2008 537 545
14. S. Rossi, A. Faccendini, M.C. Bonferoni, F. Ferrari, G. Sandri, C. Del Fante, C. Perotti, and C.M. Caramella Sponge-like dressings based on biopolymers for the delivery of platelet lysate to skin chronic wounds Int. J. Pharm. 440 2013 207 215
15. S. Rossi, F. Ferrari, M.C. Bonferoni, G. Sandri, A. Faccendini, A. Puccio, and C.M. Caramella Comparison of poloxamer- and chitosan-based thermally sensitive gels for the treatment of vaginal mucositis Drug Dev. Ind. Pharm. 2013 10.3109/03639045.2012.762654 (in press)
16. G. Sandri, M.C. Bonferoni, F. Ferrari, S. Rossi, C. Del Fante, C. Perotti, A. Gallanti, and C.M. Caramella An in situ gelling buccal spray containing platelet lysate for the treatment of oral mucositis Curr. Drug Discov. Technol. 8 2011 277 285
17. G. Sandri, M.C. Bonferoni, S. Rossi, F. Ferrari, M. Mori, C. Del Fante, C. Perotti, L. Scudeller, and C.M. Caramella Platelet lysate formulations based on mucoadhesive polymers for the treatment of corneal lesions J. Pharm. Pharmacol. 63 2011 189 198
18. G. Sandri, M.C. Bonferoni, S. Rossi, F. Ferrari, M. Mori, C. Del Fante, C. Perotti, and C.M. Caramella Thermosensitive eyedrops containing platelet lysate for the treatment of corneal ulcers Int. J. Pharm. 426 2012 1 6
19. A. Thomas, K.G. Harding, and K. Moore Aginates from wound dressing activate human macrophages to secrete tumor necrosis factor-α Biomaterials 21 2000 1797 1802 (Pubitemid 30365043)
20. S. Werner, and R. Grose Regulation of wound healing by growth factors and cytochines Physiol. Rev. 83 2003 835 870 (Pubitemid 36828927)