Platelet lysate formulations based on mucoadhesive polymers for the treatment of corneal lesions

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 2, 2011, Pages 189-198

  Sandri, Giuseppina ^a   Bonferoni, Maria Cristina ^a   Rossi, Silvia ^a   Ferrari, Franca ^a   Mori, Michela ^a   Del Fante, Claudia ^b   Perotti, Cesare ^b   Scudeller, Luigia ^b   Caramella, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

chitosan; cornea; growth factors; polyacrylic acid; wound healing

Indexed keywords

CHITOSAN; POLYACRYLIC ACID; POLYMER;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL LYSATE; CELL PROLIFERATION; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA LESION; EPITHELIUM CELL; FIBROBLAST; FLOW KINETICS; HUMAN; HUMAN CELL; MUCOADHESION; NONHUMAN; PLATELET LYSATE; RABBIT; THROMBOCYTE; WOUND HEALING;

ACRYLIC RESINS; ANIMALS; CELL EXTRACTS; CELL PROLIFERATION; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; CORNEA; CORNEAL ULCER; DELAYED-ACTION PREPARATIONS; EPITHELIUM, CORNEAL; FIBROBLASTS; PHARMACEUTICAL VEHICLES; PLATELET-RICH PLASMA; RABBITS; WOUND HEALING;

EID: 78751538795     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2010.01208.x     Document Type: Article

References (31)

1. Anitua E, et al. New insight into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 2006; 24: 227-234.
2. Borzini P, Mazzucco L,. Platelet gels and releasates. Curr Opin Hematol 2005; 12: 473-479.
3. Dohan Ehrenfest DM, Rasmusson LT,. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to Albrektsson leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol 2009; 27: 158-167.
4. Doucet C, et al. Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 2005; 205: 228-236.
5. Stacey MC, et al. Randomised double-blind placebo controlled trial of topical autologous platelet lysate in venous ulcer healing. Eur J Vasc Endovasc Surg 2000; 20: 296-301.
6. Senet P, et al. Randomized trial and local biological effect of autologous platelets used as adjuvant therapy for chronic venous leg ulcers. J Vasc Surg 2003; 38: 1342-1348.
7. A and one manual procedure. Vox Sang 2009; 97: 110-118.
8. Crovetti G, et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apher Sci 2004; 30: 145-151.
9. Intini G,. The use of platelet-rich plasma in bone reconstruction therapy. Biomaterials 2009; 30: 4956-4966.
10. Mazzucco L, et al. The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study. Transfusion 2004; 44: 1013-1018.
11. Ogino Y, et al. The contribution of platelet-derived growth factor, transforming growth factor b1, and insulin-like growth factor 1 in platelet-rich plasma to the proliferation of osteoblast-like cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101: 724-729.
12. Anitua E, et al. The potential impact of the preparation rich in growth factors (PRGF) in different medical fields. Biomaterials 2007; 28: 4551-4560.
13. Sheridan MH, et al. Bioabsorbable polymer scaffolds for tissue engineering capable of sustained growth factor delivery. J Control Release 2000; 64: 91-102.
14. Yamamoto M, et al. Bone regeneration by transforming growth factor b1 released from a biodegradable hydrogel. J Control Release 2000; 64: 133-142.
15. Désiré L, et al. Sustained delivery of growth factors from methylidene malonate 2.1.2-based polymers. Biomaterials 2006; 27: 2609-2620.
16. Ho YC, et al. Heparin-functionalized chitosan-alginate scaffolds for controlled release of growth factor. Int J Pharm 2009; 376: 69-75.
17. Caramella CM, et al. Platelet lysate and bioadhesive compositions for the prevention and treatment of mucositis. Patent application n PCT/IT2008/000744, 2008.
18. Del Fante C, et al. Platelet derived growth factors in a mucoadhesive vehicle for treatment of patients with oral mucositis in graft versus host disease. Blood 2008; 112: 4333.
19. Yamada C, et al. Autologous serum eyedrops: literature review and implications for transfusion medicine specialists. Transfusion 2008; 48: 1245-1255.
20. Zhou Q, et al. TGFb mediated transition of corneal fibroblasts from a proinflammatory state to a profibrotic state through modulation of histone acetylation. J Cell Physiol 2010; 224: 135-143.
21. Dupps WJ, Wilson SE,. Biomechanics and wound healing in the cornea. Exp Eye Res 2006; 83: 709-720.
22. Geremicca W, et al. Blood components for clinical use in tissue regeneration: evaluations of corneal lesions treated with platelet lysate and considerations on repairing mechanisms. Blood Transfus 2010; 8: 107-112.
23. Ueno H, et al. Topical formulations and wound healing applications of chitosan. Adv Drug Del Rev 2001; 52: 105-115.
24. Minagawa T, et al. Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing. Carbohydr Polym 2007; 67: 640-644.
25. Ferrari F, et al. Technological induction of mucoadhesive properties on waxy starches by grinding. Eur J Pharm Sci 1997; 5: 277-285.
26. Popiolkiewicz J, et al. In vitro toxicity evaluation in the development of new anticancer drugs-genistein glycosides. Cancer Lett 2005; 229: 67-75.
27. Fotakis G, Timbrell JA,. In vitro cytoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride. Toxicol Lett 2006; 160: 171-177.
28. Lubrizol Pharmaceutical Bulletin, Pharmaceutical Bulletin 22, Edition: October 29, 2008.
29. He L, et al. A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 707-713.
30. Valeri CR, et al. Release of platelet-derived growth factors and proliferation of fibroblasts in the releasates from platelets stored in the liquid state at 22°C after stimulation with agonists. Transfusion 2006; 46: 225-229.
31. Ryan DG, et al. Involvement of S100A4 in stromal fibroblasts of the regenerating cornea. Invest Ophthalmol Vis Sci 2003; 44: 4255-4262.