Thermosensitive eyedrops containing platelet lysate for the treatment of corneal ulcers

International Journal of Pharmaceutics

Volumn 426, Issue 1-2, 2012, Pages 1-6

  Sandri, Giuseppina ^a   Bonferoni, Maria Cristina ^a   Rossi, Silvia ^a   Ferrari, Franca ^a   Mori, Michela ^a   Del Fante, Claudia ^b   Perotti, Cesare ^b   Caramella, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Cornea; Growth factors; Mucoadhesion; Platelet lysate; Thermogelling; Wound healing

Indexed keywords

CHONDROITIN SULFATE; EYE DROPS; HYDROXYPROPYLMETHYLCELLULOSE; PLATELET DERIVED GROWTH FACTOR AB;

ANIMAL CELL; ARTICLE; CELL GROWTH; CELL LYSATE; CELL PROLIFERATION; CELL THERAPY; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA ULCER; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; EXPERIMENTAL RABBIT; HEAT SENSITIVITY; IN VITRO STUDY; MUCOADHESION; NONHUMAN; PRIORITY JOURNAL; STORAGE TEMPERATURE; THERMOGENESIS; THERMOSTABILITY; THROMBOCYTE; THROMBOCYTE LYSATE; WOUND HEALING;

ADHESIVENESS; ANIMALS; BIOLOGICAL AGENTS; BLOOD PLATELETS; CELL EXTRACTS; CELL LINE; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; CHONDROITIN SULFATES; CORNEAL ULCER; DRUG CARRIERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIUM, CORNEAL; GELS; HUMANS; METHYLCELLULOSE; OPHTHALMIC SOLUTIONS; PLATELET-DERIVED GROWTH FACTOR; RABBITS; RHEOLOGY; TEMPERATURE; WOUND HEALING;

EID: 84857791283     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.12.059     Document Type: Article

References (19)

1. E. Anitua New insight into and novel applications for platelet-rich fibrin therapies Trends Biotechnol. 24 2006 227 234
2. M.C. Bonferoni Microparticle systems based on polymer drug interaction for ocular delivery of ciprofloxacin. I. In vitro characterization J. Drug Deliv. Sci. Technol. 17 2007 57 62 (Pubitemid 46347816)
3. C. Caramella Rheological and tensile tests for the assessment of polymer-mucin interaction Eur. J. Pharm. Biopharm. 40 1994 213 217 (Pubitemid 24276310)
4. S.S. Deepa Specific molecular interactions of over sulfated chondroitin sulfate e with various heparin-binding growth factors J. Biol. Chem. 277 2002 43707 43716
5. C. Del Fante Platelet lysate mucohadesive formulation to treat oral mucositis in graft versus host disease patients: a new therapeutic approach AAPS Pharm. Sci. Technol. 12 2011 893 899
6. W.J. Dupps, and S.E. Wilson Biomechanics and wound healing in the cornea Exp. Eye Res. 83 2006 709 720 (Pubitemid 44292672)
7. W. Geremicca Blood components for clinical use in tissue regeneration: evaluations of corneal lesions treated with platelet lysate and considerations on reparing mechanisms Blood Trans. 8 2010 107 112
8. J.J. Lim Development of nano and microscale chandroitin sulfate particles for controlled growth factors delivery Acta Biomater. 7 2011 986 995
9. X.H. Lin Functions of heparan sulfate proteoglycans in cell signaling during development Development 131 2004 6009 6021
10. S.Q. Liu Effects of salts in the hofmeister series and solvent isotopes on the gelation mechanisms for hydroxypropylmethyl cellulose hydrogels J. Appl. Polym. Sci. 109 2008 363 372
11. L. Lu, P.S. Reinach, and W.W. Kao Corneal epithelial wound healing Exp. Biol. Med. 226 2001 653 664 (Pubitemid 32619604)
12. L. Macri, D. Silverstein, and R.A.F. Clark Growth factor binding to the pericellular matrix and its importance in tissue engineering Adv. Drug Deliv. Rev. 59 2007 1366 1381 (Pubitemid 350090013)
13. G. Sandri Platelet lysate formulations based on mucoadhesive polymers for the treatment of corneal lesions J. Pharm. Pharmacol. 63 2011 189 198
14. N. Sarkar Kinetics of thermal gelation of methylcellulose and hydroxypropylmethylcellulose in aqueous solutions Carbohydrate Polym. 26 1995 195 203
15. M. Szcs Mucoadhesive behaviour of emulsion containing polymeric emulsifier Eur. J. Pharm. Sci. 34 2008 226 235
16. A.H.H. Talasaz In situ gel forming systems of poloxamer 407 and hydroxypropyl cellulose or hydroxypropyl methyl cellulose mixtures for controlled delivery of vancomycin J. Appl. Polym. Sci. 109 2008 2369 2374
17. C. Yamada Autologous serum eyedrops: literature review and implications for transfusion medicine specialists Transfusion 48 2008 1245 1255 (Pubitemid 351793487)
18. F.-S.X. Yu Growth factors and corneal epithelial wound healing Brain Res. Bull. 81 2010 229 235
19. X.H. Zou Specific interactions between human fibroblasts and particular chondroitin sulfate molecules for wound healing Acta Biomater. 5 2009 1588 1595