Platelet lysate mucohadesive formulation to treat oral mucositis in graft versus host disease patients: A new therapeutic approach

AAPS PharmSciTech

Volumn 12, Issue 3, 2011, Pages 893-899

  Del Fante, Claudia ^a   Perotti, Cesare ^a   Bonferoni, Maria Cristina ^b   Rossi, Silvia ^b   Sandri, Giuseppina ^b   Ferrari, Franca ^b   Scudeller, Luigia ^a   Caramella, Carla Marcella ^b  

^a FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

in vitro proliferation and wound healing test; in vivo assessment in graft versus host disease; mucositis; platelet lysate growth factors

Indexed keywords

DRUG VEHICLE; PLATELET DERIVED GROWTH FACTOR; PLATELET LYSATE MUCOADHESIVE FORMULATION; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; BIOCOMPATIBILITY; CELL LYSATE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FEASIBILITY STUDY; FIBROBLAST; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUTH CAVITY; MUCOADHESION; PRIORITY JOURNAL; STOMATITIS; THROMBOCYTE; WOUND HEALING;

ACRYLATES; ADMINISTRATION, BUCCAL; ADOLESCENT; ADULT; BLOOD PLATELETS; CELL EXTRACTS; CELL PROLIFERATION; CELLS, CULTURED; FIBROBLASTS; GRAFT VS HOST DISEASE; HUMANS; MIDDLE AGED; MOUTH MUCOSA; PLATELET-DERIVED GROWTH FACTOR; STOMATITIS; TISSUE ADHESIVES; VISCOSITY; WOUND HEALING;

EID: 80052588683     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-011-9649-3     Document Type: Article

References (16)

1. S Vokurka K Steinerova M Karas V Koza 2009 Characteristics and risk factors of oral mucositis after allogeneic stem cell transplantation with FLU/MEL conditioning regimen in context with BU/CY2 Bone Marrow Transplant 44 601 605 19349956 10.1038/bmt.2009.66 1:STN:280:DC%2BD1MjltVKjsA%3D%3D
2. NM Blijlevens 200 Implications of treatment-induced mucosal barrier injury Curr Opin Oncol 17 605 610
3. HV Worthington JE Clarkson OB Eden 2007 Interventions for preventing oral mucositis for patients with cancer receiving treatment Cochrane Database Syst Rev 4 CD000978 17943748
4. WJ van der Velden AH Herbers NM Blijlevens 2009 Palifermin in allogeneic HSCT: many questions remain Bone Marrow Transplant 43 85 86 18762763 10.1038/bmt.2008.269
5. S Langner P Staber N Schub M Gramatzki W Grothe G Behre W Rabitsch C Urban W Linkesch P Neumeister 2008 Palifermin reduces incidence and severity of oral mucositis in allogeneic stem-cell transplant recipients Bone Marrow Transplant 42 275 279 18500368 10.1038/bmt.2008.157 1:CAS:528:DC%2BD1cXhtVGgtbrP
6. E Gori M Arpinati F Bonifazi A Errico A Mega F Alberani V Sabbi G Costazza S Leanza C Borrelli M Berni C Feraut E Polato MC Altieri E Pirola MC Loddo M Banfi L Barzetti S Calza C Brignoli G Bandini A De Vivo A Bosi AM Baccarani 2007 Cryotherapy in the prevention of oral mucositis in patients receiving low-dose methotrexate following myeloablative allogeneic stem cell transplantation: a prospective randomized study of the Gruppo Italiano Trapianto di Midollo Osseo nurses group Bone Marrow Transplant 39 347 352 17277790 10.1038/sj.bmt.1705590 1:CAS:528:DC%2BD2sXisVKrtL8%3D (Pubitemid 46403926)
7. M Crowther A Avenell DJ Culligan 2009 Systematic review and meta-analyses of studies of glutamine supplementation in haematopoietic stem cell transplantation Bone Marrow Transplant 44 413 425 19270730 10.1038/bmt.2009.41 1:CAS:528:DC%2BD1MXht1KrtbzL
8. L Mazzucco D Medici M Serra R Panizza G Rivara S Orecchia R Libener E Cattana A Levis PG Betta P Borzini 2004 The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study Transfusion 44 1013 1018 15225241 10.1111/j.1537-2995.2004.03366.x 1:CAS:528:DC%2BD2cXmt1ClsL0%3D (Pubitemid 38823807)
9. VS Rajkumar X Shiwen M Bostrom P Leoni J Muddle M Ivarsson B Gerdin CP Denton G Bou-Gharios CM Black DJ Abraham 2006 Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing Am J Pathol 169 2254 2265 17148686 10.2353/ajpath.2006.060196 1:CAS:528:DC%2BD2sXhvV2nug%3D%3D (Pubitemid 351181983)
10. E Anitua M Sanchez AT Nurden P Nurden G Orive I Andia 2006 New insights into and novel applications for platelet-rich fibrin therapies Trends Biotechnol 24 227 234 16540193 10.1016/j.tibtech.2006.02.010 1:CAS:528: DC%2BD28XktVeiu7g%3D
11. P Borzini L Mazzucco 2005 Platelet gels and releasates Curr Opin Hematol 12 473 479 16217165 10.1097/01.moh.0000177831.70657.e8 (Pubitemid 41546479)
12. MC Bonferoni G Sandri S Rossi F Ferrari S Gibin C Caramella 2008 Chitosan citrate as multifunctional polymer for vaginal delivery. Evaluation of penetration enhancement and peptidase inhibition properties Eur J Pharm Sci 5 33 166 176 10.1016/j.ejps.2007.11.004
13. C Perotti C Del Fante C Tinelli G Viarengo L Scudeller M Zecca F Locatelli L Salvaneschi 2010 Extracorporeal photochemotherapy in graft-versus-host disease: a longitudinal study on factors influencing the response and survival in pediatric patients Transfusion 50 1359 1369 20113452 10.1111/j.1537-2995.2009.02577.x
14. Lubrizol Pharmaceutical Bulletin 23: Bioadhesion, http://www.lubrizol. com/Pharmaceutical/Literature/Bulletins.html
15. A Picardi A Lanti L Cudillo R Cerretti T Dentamaro G De Angelis A Ferraro A Di Veroli G Adorno W Arcese 2009 Platelet gel for treatment of mucocutaneous lesions related to graft-versus-host disease after allogeneic hematopoietic stem cell transplant Transfusion 50 501 506 19821947 10.1111/j.1537-2995.2009.02439. x
16. MM Imanguli SZ Pavletic JP Guadagnini JS Brahim JC Atkinson 2006 Chronic graft versus host disease of oral mucosa: review of available therapies Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101 175 183 16448918 10.1016/j.tripleo.2005.08.028 (Pubitemid 43163216)