Double suicide gene therapy using human neural stem cells against glioblastoma: Double safety measures

Journal of Neuro-Oncology

Volumn 116, Issue 1, 2014, Pages 49-57

  Lee, Ji Yeoun ^a,b   Lee, Do Hun ^c   Kim, Hyung A ^a,b   Choi, Seung Ah ^a,b   Lee, Hong Jun ^d   Park, Chul Kee ^e   Phi, Ji Hoon ^a,b   Wang, Kyu Chang ^a   Kim, Seung U ^d,f   Kim, Seung Ki ^a,b  

^a Seoul National University Children's Hospital   (South Korea)

^b Seoul National University Cancer Hospital   (South Korea)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d Chung Ang University College of Medicine   (South Korea)

^e Seoul National University Hospital   (South Korea)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Double suicide gene; Neural stem cell; Safety; Stem cell based gene therapy

Indexed keywords

CYTOSINE DEAMINASE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER LOCALIZATION; CANCER SURVIVAL; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SAFETY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEURAL STEM CELL; NONHUMAN; RAT; SUICIDE GENE THERAPY; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR VOLUME;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN NEOPLASMS; CELL MOVEMENT; CELL SURVIVAL; DISEASE MODELS, ANIMAL; GENES, TRANSGENIC, SUICIDE; GENETIC THERAPY; GLIOBLASTOMA; HUMANS; KI-67 ANTIGEN; MICE; MICE, INBRED BALB C; MICE, NUDE; NEURAL STEM CELLS;

EID: 84891754509     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-013-1264-6     Document Type: Article

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