Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 4, 2007, Pages 1337-1341

  Ahmad, Shoeb ^a   Tang, Wenxue ^a   Chang, Qing ^a   Qu, Yan ^a   Hibshman, Jill ^a   Li, Yuhua ^a   Söhl, Goran ^b   Willecke, Klaus ^b   Chen, Ping ^a   Lin, Xi ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Gap junction; Hearing rescue; Hereditary deafness

Indexed keywords

CONNEXIN 26; CONNEXIN 30;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL CHROMOSOME; CELL DEATH; COCHLEA; CONTROLLED STUDY; GAP JUNCTION; GENE EXPRESSION; GENE MUTATION; HAIR CELL; HEARING ACUITY; HEARING IMPAIRMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL DEATH; COCHLEA; CONNEXINS; DEAFNESS; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HAIR CELLS; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION;

BACTERIA (MICROORGANISMS); MUS;

EID: 33846590621     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0606855104     Document Type: Article

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