Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion

Cellular Physiology and Biochemistry

Volumn 33, Issue 1, 2014, Pages 23-36

  Kang, Jung Woo ^a   Cho, Hong Ik ^a   Lee, Sun Mee ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

Autophagy; Calpain; Ischemia reperfusion; Mammalian target of rapamycin; Melatonin; Oxidative stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BECLIN 1; CALPAIN 1; CALPAIN 2; CASPASE 3; GLUTATHIONE; GLUTATHIONE DISULFIDE; MAMMALIAN TARGET OF RAPAMYCIN; MELATONIN; PROTEIN P62; RAPAMYCIN; INITIATION FACTOR 4E BINDING PROTEIN 1; PROTEIN; PROTEIN 70S6K; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; CALPAIN; PROTECTIVE AGENT; TARGET OF RAPAMYCIN KINASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOPHAGOSOME; AUTOPHAGY; CELL PROTECTION; CELL VACUOLE; CONTROLLED STUDY; LIPID PEROXIDATION; LIVER CELL DAMAGE; LIVER INJURY; LIVER ISCHEMIA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; CYTOSOLIC FRACTION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; LIVER PROTECTION; PROTEIN DEGRADATION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; LIVER; LIVER CELL; METABOLISM; PATHOLOGY; TIME FACTOR; ULTRASTRUCTURE; VASCULARIZATION;

MAMMALIA; MUS;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CALPAIN; HEPATOCYTES; LIVER; MELATONIN; MICE, INBRED C57BL; OXIDATIVE STRESS; PROTECTIVE AGENTS; REPERFUSION INJURY; SIROLIMUS; TIME FACTORS; TOR SERINE-THREONINE KINASES;

EID: 84891709303     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356647     Document Type: Article

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