The frequency of α4β7(high) memory CD4+ T cells correlates with susceptibility to rectal simian immunodeficiency virus infection.

Journal of acquired immune deficiency syndromes (1999)

Volumn 64, Issue 4, 2013, Pages 325-331

  Martinelli, Elena ^a   Veglia, Filippo ^b   Goode, Diana ^b   Guerra Perez, Natalia ^b   Aravantinou, Meropi ^b   Arthos, James ^b   Piatak, Michael ^b   Lifson, Jeffrey D ^b   Blanchard, James ^b   Gettie, Agegnehu ^b   Robbiani, Melissa ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

ANIMAL; CD4+ T LYMPHOCYTE; CLASSIFICATION; DISEASE PREDISPOSITION; FLOW CYTOMETRY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MALE; METABOLISM; PHYSIOLOGY; RECTUM; RHESUS MONKEY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE SUSCEPTIBILITY; FLOW CYTOMETRY; IMMUNOLOGIC MEMORY; INTEGRINS; MACACA MULATTA; MALE; RECTUM; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84891703277     PISSN: None     EISSN: 19447884     Source Type: Journal    
DOI: 10.1097/qai.0b013e31829f6e1a     Document Type: Article

References (35)

1. Lancet Infect Dis Boily 9 118 2009 10.1016/S1473-3099(09)70021-0. Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies.
2. Top HIV Med Cohen 12 104 2004 HIV and sexually transmitted diseases: lethal synergy.
3. Nat Rev Microbiol Galvin 2 33 2004 10.1038/nrmicro794 The role of sexually transmitted diseases in HIV transmission.
4. Nature Haase 464 217 2010 10.1038/nature08757 Targeting early infection to prevent HIV-1 mucosal transmission.
5. Proc Natl Acad Sci USA Cicala 106 20877 2009 10.1073/pnas.0911796106. The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.
6. J Med Primatol Kader 38 suppl 1 24 2009 10.1111/j.1600-0684.2009.00372.x. CD4 T cell subsets in the mucosa are CD28Ki-67-HLA-DR-CD69 but show differential infection based on alpha4beta7 receptor expression during acute SIV infection.
7. Nat Med Zhu 15 886 2009 10.1038/nm.2006. Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition.
8. Mucosal Immunol Kader 2 439 2009 10.1038/mi.2009.90. Alpha4()beta7(hi)CD4() memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.
9. Mucosal Immunol Wang 2 518 2009 10.1038/mi.2009.104. Monitoring alpha4beta7 integrin expression on circulating CD4 T cells as a surrogate marker for tracking intestinal CD4 T-cell loss in SIV infection.
10. J Immunol Ansari 186 1044 2011 10.4049/jimmunol.1003052. Blocking of alpha4beta7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques.
11. Curr Mol Med Gorfu 9 836 2009 10.2174/156652409789105525 Role of beta7 integrins in intestinal lymphocyte homing and retention.
12. J Immunol Trimble 185 7107 2010 10.4049/jimmunol.1002756. Human papillomavirus 16-associated cervical intraepithelial neoplasia in humans excludes CD8 T cells from dysplastic epithelium.
13. J Infect Dis Kelly 184 885 2001 10.1086/323341. Chlamydia trachomatis infection induces mucosal addressin cell adhesion molecule-1 and vascular cell adhesion molecule-1, providing an immunologic link between the fallopian tube and other mucosal tissues.
14. J Transl Med Cicala 9 suppl 1 S2 2011 10.1186/1479-5876-9-S1-S2 HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV.
15. PLoS Pathog Nawaz 7 e1001301 2011 10.1371/journal.ppat.1001301. The genotype of early-transmitting HIV gp120s promotes alpha(4)beta(7)-reactivity, revealing alpha(4)beta(7)CD4 T cells as key targets in mucosal transmission.
16. J Virol Singer 85 5504 2011 10.1128/JVI.02422-10. The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simianhuman immunodeficiency virus infection in macaques.
17. J Virol Lifson 75 10187 2001 10.1128/JVI.75.21.10187-10199.2001. Role of CD8() lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment.
18. J Med Primatol Cline 34 303 2005 10.1111/j.1600-0684.2005.00128.x. Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS.
19. Nat Immunol Arthos 9 301 2008 10.1038/ni1566. HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
20. Clin Vaccine Immunol Campbell 17 1148 2010 10.1128/CVI.00533-09. Analytical and biological considerations in the measurement of cell-associated CCR5 and CXCR4 mRNA and protein.
21. Nature Mattapallil 434 1093 2005 10.1038/nature03501. Massive infection and loss of memory CD4 T cells in multiple tissues during acute SIV infection.
22. Cell Pope 78 389 1994 10.1016/0092-8674(94)90418-9. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1.
23. Adv Exp Med Biol Pope 417 395 1997 10.1007/978-1-4757-9966-8_64. Cutaneous dendritic cells promote replication of immunodeficiency viruses.
24. Curr Top Microbiol Immunol Steinman 276 1 2003. The interaction of immunodeficiency viruses with dendritic cells.
25. J Leukoc Biol Teleshova 74 683 2003 10.1189/jlb.0403178 Immunodeficiency virus exploitation of dendritic cells in the early steps of infection.
26. AIDS Res Ther Langford 4 11 2007 10.1186/1742-6405-4-11 Predictors of disease progression in HIV infection: a review.
27. Crit Rev Immunol Denucci 29 87 2009 10.1615/CritRevImmunol.v29.i2.10 Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there.
28. J Virol Stone 84 7083 2010 10.1128/JVI.00481-10. A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251.
29. Proc Natl Acad Sci USA Keele 105 7552 2008 10.1073/pnas.0802203105. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.
30. J Virol Gnanadurai 84 12245 2010 10.1128/JVI.01603-10. Genetic identity and biological phenotype of a transmittedfounder virus representative of nonpathogenic simian immunodeficiency virus infection in African green monkeys.
31. J Virol Chohan 79 6528 2005 10.1128/JVI.79.10.6528-6531.2005. Selection for human immunodeficiency virus type 1 envelope glycosylation variants with shorter V1-V2 loop sequences occurs during transmission of certain genetic subtypes and may impact viral RNA levels.
32. Am J Reprod Immunol Kelly 61 438 2009 10.1111/j.1600-0897.2009.00704.x. Two different homing pathways involving integrin beta7 and E-selectin significantly influence trafficking of CD4 cells to the genital tract following Chlamydia muridarum infection.
33. Blood Kwa 118 2763 2011 10.1182/blood-2011-02-339515. Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques.
34. Immunol Rev Kelsall 206 132 2005 10.1111/j.0105-2896.2005.00292.x Involvement of intestinal dendritic cells in oral tolerance, immunity to pathogens, and inflammatory bowel disease.
35. Semin Immunol Johansson 17 284 2005 10.1016/j.smim.2005.05.010 Phenotype and function of intestinal dendritic cells.