Investigating the relationship between COMT polymorphisms and working memory performance among childhood brain tumor survivors

Pediatric Blood and Cancer

Volumn 61, Issue 1, 2014, Pages 40-45

  Howarth, Robyn A ^a   Adamson, Amanda M ^a   Ashford, Jason M ^b   Merchant, Thomas E ^b   Ogg, Robert J ^b   Schulenberg, Stefan E ^c   Ogg, Susan ^b   Li, Jiang ^d   Wu, Shengjie ^b   Xiong, Xiaoping ^b   Conklin, Heather M ^b  

^a Department of Neuropsychology Children's Healthcare of Atlanta ^*  (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF MISSISSIPPI   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cancer; Dopamine; Genetics; Late effects; Prefrontal cortex; Working memory

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ADOLESCENT; ARTICLE; BRAIN TUMOR; CANCER RADIOTHERAPY; CHEEK MUCOSA; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; COGNITION; DNA EXTRACTION; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; TASK PERFORMANCE; VERBAL MEMORY; WORKING MEMORY; ADULT; CANCER SURVIVOR; COMPUTER ASSISTED RADIOTHERAPY; CRANIOPHARYNGIOMA; DNA POLYMORPHISM; EPENDYMOMA; GLIOMA; ORAL BIOPSY; BRAIN NEOPLASMS; GENETICS; NEUROPSYCHOLOGICAL TEST; PRESCHOOL CHILD; RADIATION RESPONSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHORT TERM MEMORY; SINGLE NUCLEOTIDE POLYMORPHISM; SKULL IRRADIATION; SURVIVOR;

ADOLESCENT; BRAIN NEOPLASMS; CATECHOL O-METHYLTRANSFERASE; CHILD; CHILD, PRESCHOOL; CRANIAL IRRADIATION; FEMALE; GENOTYPE; HUMANS; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, SINGLE NUCLEOTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SURVIVORS;

EID: 84891687226     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24649     Document Type: Article

References (43)

1. Mostow EN, Byrne J, Connelly RR, et al. Quality of life in long-term survivors of CNS tumours of childhood and adolescence. J Clin Oncol 1991;9:592-599.
2. Mulhern RK, Merchant TM, Gajjar A, et al. Late neurocognitive sequelae in survivors of brain tumours in childhood. Lancet 2004;5:399-408.
3. Ris MD, Packer R, Goldwein J, et al. Intellectual outcome after reduced-dose radiation therapy plus adjuvant chemotherapy for medulloblastoma: A Children's Cancer Group Study. J Clin Oncol 2001;19:3470-3476.
4. Law N, Bouffet E, Laughlin S, et al. Cerebello-thalamo-cerebral connections in pediatric brain tumor patients: Impact on working memory. Neuroimage 2011;56:2238-2248.
5. Wechsler D.Wechsler intelligence scale for children, 4th edition, integrated. Psychological Corporation, San Antonio, TX: 2003.
6. Baddeley A. Working memory. Oxford, England: Oxford University Press; 1986.
7. D'Esposito M, Postle BR, Rypma B. Prefrontal cortical contributions to working memory: Evidence from event-related fMRI studies. Exp Brain Res 2000;133:3-11.
8. Goldman-Rakic PS. Architecture of the prefrontal cortex and the central executive. Ann N YAcad Sci 1995;769:71-83.
9. Petrides M, Alivisatos B, Meyer E, et al. Functional activation of the human frontal cortex during performance of verbal working memory tasks. Proc Natl Acad Sci USA 1993;90:878-882.
10. Smith EE, Jonides J. Neuroimaging analyses of human working memory. Proc Natl Acad Sci USA 1998;95:12061-12068.
11. Packer RJ, Gurney JG, Punyko JA, et al. Long-term neurologic and neurosensory sequelae in adult survivors of a childhood brain tumor: Childhood cancer survivor study. J Clin Oncol 2003;21:3255- 3261.
12. Reddick WE, White HA, Glass JO, et al. Developmental model relating white matter volume to neurocognitive deficits in pediatric brain tumor survivors. Cancer 2003;97:2512-2519.
13. Ahles TA, Saykin AJ, Noll WW, et al. The relationship of APOE genotype to neuropsychological performance in long-term cancer survivors treated with standard dose chemotherapy. Psychooncology 2003;12:612-619.
14. Ferguson RJ, McDonald BC, Saykin AJ, et al. Brain structure and function differences in monozygotic twins: Possible effects of breast cancer chemotherapy. J Clin Oncol 2007;25:3866-3870.
15. Silverman DHS, Dy CJ, Castellon SA, et al. Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5-10 years after chemotherapy. Breast Cancer Res Treat 2007;103:303-311.
16. Mabbott DJ, Noseworthy MD, Bouffet E, et al. Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: Correlation with IQ. Neurooncol 2006;8:244-252.
17. Krull KR, Brouwers P, Jain N, et al. Folate pathway genetic polymorphisms are related to attention disorders in childhood leukemia survivors. J Pediatr 2008;152:101-105.
18. Krajinovic M, Labuda D, Mathonnet G, et al. Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes,DNArepair enzymes, and response to treatment of childhood acute lymphoblastic leukemia. Clin Can Res 2002;8:802-810.
19. Stenzel SL, Krull KR, Hockenberry M, et al. Oxidative stress and neurobehavioral problems in pediatric acute lymphoblastic leukemia patients undergoing chemotherapy. J Pediatr Hematol Oncol 2010;32:113- 118.
20. Diamond A, Goldman-Rakic P. Comparison of human infants and rhesus monkeys on Piaget's A-not-B task: Evidence for dependence on dorsolateral prefrontal cortex. Exp Brain Res 1989;74:24-40.
21. Mattay VS, Goldberg TE, Fera F, et al. Catechol O-methyltransferase Val158Met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA 2003;100:6186-6191.
22. Blasi G, Mattay VS, Bertolino A, et al. Effect of catechol-O-methyltransferase Val158Met genotype on attentional control. J Neurosci 2005;25:5038-5045.
23. Meyer-Lindenberg A, Kohn PD, Kolachana B, et al. Midbrain dopamine and prefrontal function in humans: Interaction and modulation by COMT genotype. Nat Neurosci 2005;8:594-596.
24. Palmatier MA, Kang AM, Kidd KK. Global variation in the frequencies of functionally different catechol- O-methyltransferase alleles. Biol Psychiatry 1999;46:557-567.
25. Egan MF, Goldberg TE, Kolachana BS, et al. Effect of COMT Val108/58Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci USA 2001;98:6917-6922.
26. Malhotra AK, Kestler LJ, Mazzanti C, et al. A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am J Psychiatry 2002;159:652-654.
27. Goldberg TE, Egan MF, Gscheidle T, et al. Executive subprocesses in working memory: Relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Arch Gen Psychiatry 2003; 60:889-896.
28. Bruder GE, Keilp JG. Xu H, et al. Catechol-O-methyltransferase (COMT) genotypes and working memory: Associations with differing cognitive operations. Biol Psychiatry 2005;58:901-907.
29. Diamond A, Briand L, Fossella J, et al. Genetic and neurochemical modulation of prefrontal cognitive functions in children. Am J Psychiatry 2004;161:125-132.
30. Wahlstrom D, White T, Hooper CJ, et al. Variations in the catechol-O-methyltransferase polymorphism and prefrontally guided behaviors in adolescents. Biol Psychiatry 2007;61:626-632.
31. Small BJ, Rawson KS, Walsh E, et al. Catechol-O-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors. Cancer 2011;117:1369-1376.
32. Conklin HM, Ashford JA, Howarth RA, et al. Working memory performance among childhood brain tumor survivors. J Int Neuropsychol Soc 2012;
33. Wechsler D. Wechsler abbreviated scale of intelligence. San Antonio, TX: Harcourt Assessment; 1999.
34. Wechsler D, Wechsler Adult. Intelligence scale, 3rd edition. San Antonio, TX: Psychological Corporation; 1999.
35. Barr CL, Wigg K, Malone M, et al. Linkage study of catechol-O-methyltransferase and attention deficit hyperactivity disorder. Am J Med Genet 1999;88:710-713.
36. Barratt WR, The Barratt Simplified Measure of Social Status. Retrieved from the Indiana State University website: http://wbarratt.indstate.edu/socialclass/BarrattSimplifed_Measure_of_Social_Status.pdf; 2006.
37. Vijayraghavan S, Wang M, Birnbaum SG, et al. Inverted-U dopamine D1 receptor actions on prefrontal neurons engaging in working memory. Nat Neurosci 2007;10:376-384.
38. Goldman-Rakic PS. The cortical dopamine system: Role in memory and cognition. Adv Pharmacol 1998;42:707-711.
39. Granon S, Passetti F, Thomas KL, et al. Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex. J Neurosci 2000;20:1208-1215.
40. Wardle MC, deWit H, Penton-Voak I, et al. Lack of association between COMTand working memory in a population-based cohort of healthy young adults. Neuropsychopharmacology 2013; 1-11.
41. Sesack SR, Hawrylak VA, Matus C, et al. Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J Neurosci 1998;18:2697-2708.
42. Thierry AM, Tassen JF, Blanc G, et al. Discovery of the mesocortical dopamine system: Some pharmacological and functional characteristics. In: Costa E, Gessa GL, editors. Advances in biochemical psychopharmacology. New York: Raven Press; 1977.
43. Wager TD, Smith EE. Neuroimaging studies of working memory: A meta-analysis. Cogn Affect Behav Neurosci 2003;3:255-274.