Variations in the Catechol O-methyltransferase Polymorphism and Prefrontally Guided Behaviors in Adolescents

Biological Psychiatry

Volumn 61, Issue 5, 2007, Pages 626-632

  Wahlstrom, Dustin ^a   White, Tonya ^a   Hooper, Catalina J ^a   Vrshek Schallhorn, Suzanne ^a   Oetting, William S ^a   Brott, Marcia J ^a   Luciana, Monica ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Adolescence; cognition; dopamine; genetics; neuropsychology; prefrontal cortex

Indexed keywords

CATECHOL METHYLTRANSFERASE; METHIONINE; VALINE;

ADOLESCENCE; ADOLESCENT; ARTICLE; ATTENTION; CHILD; CHILD BEHAVIOR; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR COORDINATION; MOTOR PERFORMANCE; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; WORKING MEMORY;

ADOLESCENT; ANALYSIS OF VARIANCE; ATTENTION; CATECHOL O-METHYLTRANSFERASE; CHILD; FEMALE; GENOTYPE; HUMANS; MALE; MEMORY, SHORT-TERM; MENTAL PROCESSES; METHIONINE; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, GENETIC; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE; REACTION TIME; VALINE;

EID: 33847352916     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2006.05.045     Document Type: Article

References (60)

1. Abi-Dargham A., Mawlawi O., Lombardo I., Gil R., Martinez D., Huang Y., et al. Prefrontal dopamine D1 receptors and working memory in schizophrenia. J Neurosci 22 (2002) 3708-3719
2. d-amphetamine sensitization in periadolescent mice compared with adult mice. Behav Neurosci 112 (1998) 1152-1166
3. Andersen S.L., Dumont N.L., and Teicher M.H. Developmental differences in dopamine synthesis inhibition by (+/-)-7-OH-DPAT. Naunyn Schmiedebergs Arch Pharmacol 356 (1997) 173-181
4. Banken J.A. Clinical utility of considering digits forward and digits backward as separate components of the Wechsler Adult Intelligence Scale-Revised. J Clin Psychol 41 (1985) 686-691
5. Bellgrove M.A., Domschke K., Hawi Z., Kirley A., Mullins C., Robertson I.H., et al. The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD. Exp Brain Res (2005). http://www.springerlink.com/media/MFTA2GMGWG7QF0GUUBEX/Contributions/M/F /7/E/MF7ELW7ME7699THB_html/fulltext.html Available: http://www.springerlink.com/media/MFTA2GMGWG 7QF0GUUBEX/Contributions/M/F/7/E/MF7ELW7ME7699THB_html/fulltext.html (accessed June 6, 2005)
6. Coulter C.L., Happe H.K., and Murrin L.C. Postnatal development of the dopamine transporter: A quantitative autoradiographic study. Dev Brain Res 92 (1996) 172-181
7. Diamond A., Briand L., Fossella J., and Gehlbach L. Genetic and neurochemical modulation of prefrontal cognitive functions in children. Am J Psychiatry 161 (2004) 125-132
8. 108/158Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci of U S A 98 (2001) 6917-6922
9. Glatt S.J., Faraone S.V., and Tsuang M.T. Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: Meta-analysis of case-control and family-based studies. Am J Psychiatry 160 (2003) 469-476
10. Glickstein S.B., DeSteno D.A., Hof P.R., and Schmauss C. Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention. Cereb Cortex 15 (2005) 1016-1024
11. Gogos J., Morgan M., Luine V., Santha M., Ogawa S., Pfaff D., and Karayiorgou M. Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci U S A 95 (1998) 9991-9996
12. Goldberg T.E., Egan M.F., Gscheidle T., Coppola R., Weickert T., Kolachana B.S., et al. Executive subprocesses in working memory: Relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Arch Gen Psychiatry 60 (2003) 889-896
13. Goldman-Rakic P.S. The cortical dopamine system: Role in memory and cognition. Adv Pharmacol 42 (1998) 707-711
14. Goldman-Rakic P.S., and Brown R.M. Regional changes in monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys. Neuroscience 6 (1981) 177-187
15. Granon S., Passetti F., Thomas K.L., Dalley J.W., Everitt B.J., and Robbins T.W. Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex. J Neurosci 20 (2000) 1208-1215
16. Grossman M.H., Emanuel B.S., and Budaf M.L. Chromosomal mapping of the human catechol O-methyltransferase gene to 22q11.1-q11.2. Genomics 12 (1992) 822-825
17. Halstead W.C. Brain and Intelligence. A Quantitative Study of the Frontal Lobes (1947), University of Chicago Press, Chicago
18. Huotari M., Gogos J., Karayiorgou M., Koponen O., Forsberg M., Raasmaja A., et al. Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice. Eur J Neurosci 15 (2002) 246-256
19. Kalsbeek A., Voorn P., Buijs R.M., Pool C.W., and Uylings H.B.M. Development of the dopaminergic innervation in the prefrontal cortex of the rat. J Comp Neurol 269 (1998) 58-72
20. Kaufman A.S., McLean J., and Reynolds C. Analysis of WAIS-R factor patterns by sex and race. J Clin Psychol 47 (1991) 548-557
21. Lachman H.M., Papolos D.F., Saito T., Yu Y.M., Szumlanski C., and Weinshilboum R. Human catechol O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6 (1996) 243-250
22. Laviola G., Wood R.G., Kuhn C., and Francis R.L.P. Cocaine sensitization in preiadolescent and adult rats. J Psychopharmacol Exp Ther 275 (1995) 345-357
23. 1 dopamine receptors in the medial prefrontal cortex, striatum and nucleus accumbens of normal and neonatal 6-hydroxydopamine treated rats: A quantitative autoradiographic analysis. Dev Brain Res 62 (1991) 109-114
24. Lezak M.D., Howieson D.B., and Loring D.W. Neuropsychological Assessment. 4th ed (2004), Oxford University Press, New York
25. Lotta T., Vidgren J., Tilgmann C., Ulmanen I., Melén K., Julkunen I., and Taskinen J. Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 34 (1995) 4202-4210
26. Luciana M., and Collins P.F. Dopaminergic modulation of working memory for spatial but not object cues in normal humans. J Cog Neurosci 9 (1997) 330-347
27. Luciana M., Depue R.A., Arbisi P., and Leon A. Facilitation of working memory in humans by a D2 dopamine receptor agonist. J Cog Neurosci 4 (1992) 58-68
28. Luciana M., Hanson K.L., and Whitley C.B. A preliminary report on dopamine system reactivity in PKU: Acute effects of haloperidol on neuropsychological, physiological, and neuroendocrine functions. Psychopharmacology 175 (2004) 18-25
29. Malhotra A.K., Kestler L.J., Mazzanti C., Bates J.A., Goldberg T., and Goldman D. A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. Am J Psychiatry 159 (2002) 652-654
30. 158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci U S A 100 (2003) 6186-6191
31. Marshall W.A., and Tanner J.M. Variations in pattern of pubertal changes in girls. Arch Dis Child 44 (1969) 291-303
32. Marshall W.A., and Tanner J.M. Variations in pattern of pubertal changes in boys. Arch Dis Child 45 (1970) 13-23
33. 158Met genotype and performance on neuropsychological tasks in children with ADHD: A case-control study. BMC Psychiatry 4 (2004) 15-19
34. Monchi O., Petrides M., Doyon J., Postuma R.B., Worsley K., and Dagher A. Neural bases of set-shifting deficits in Parkinson's disease. J Neurosci 24 (2004) 702-710
35. Munafo M.R., Bowes L., Clark T.G., and Flint J. Lack of association of the COMT (Val(158/108) Met) gene and schizophrenia: A meta-analysis of case-control studies. Mol Psychiatry (2005). http://www.nature.com/cgitaf/DynaPage.taf?file=/mp/journal/vaop/ncurrent /full/4001664a.html&filetype=pdf Available: http://www.nature.com/cgitaf/DynaPage.taf?file=/mp/journal/vaop/ncurrent /full/4001664a.html&filetype=pdf (accessed June 6, 2005)
36. Moron J.A., Brockington A., Wise R.A., Rocha B.A., and Hope B.T. Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: Evidence from knock-out mouse lines. J Neurosci 22 (2002) 389-395
37. Napolitano A., Cesura A.M., and Da Prada M. The role of monoamine oxidase and catechol O-methyltransferase in dopaminergic neurotransmission. J Neural Transm 45 (1995) 35-45
38. Oldfield R.C. The assessment and analysis of handedness: The Edinburgh Inventory. Neuropsychologia 9 (1971) 97-113
39. Rosa A., Peralta V., Cuesta M.J., Zarzuela A., Serrano F., Martinez-Larrea A., and Fananas L. New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis. Am J Psychiatry 161 (2004) 1110-1112
40. Rosenberg D.R., and Lewis D.A. Changes in the dopaminergic innervation of monkey prefrontal cortex during late postnatal development: A tyrosine hydroxylase immunohistochemical study. Biol Psychiatry 36 (1994) 272-277
41. Rosenberg D.R., and Lewis D.A. Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: A tyrosine hydroxylase immunohistochemical analysis. J Comp Neurol 358 (1995) 383-400
42. Roy E.A., and Square-Storer P.A. Evidence for common expressions of apraxia. In: Hammond G.R. (Ed). Cerebral Control of Speech and Limb Movements (1990), North-Holland, Amsterdam 477-502
43. Sawaguchi T., and Goldman-Rakic P.S. D1 dopamine receptors in prefrontal cortex: Involvement in working memory. Science 251 (1991) 947-950
44. Seeman P., Bzowej N.H., Guan H.C., Bergeron C., Becker L.E., Reynolds G.P., et al. Human brain dopamine receptors in children and aging adults. Synapse 1 (1987) 399-404
45. Servan-Schreiber D., Carter C.S., Bruno R.M., and Cohen J.D. Dopamine and the mechanisms of cognition: Part II. D-amphetamine effects in human subjects performing a selective attention task. Biol Psychiatry 43 (1998) 723-729
46. Sesak S.R., Hawrylak V.A., Matus C., Guido M.A., and Levey A.I. Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J Neurosci 18 (1998) 2697-2708
47. Spear L.P., and Brake S.C. Periadolescence: Age-dependent behavior and psychopharmacological responsivity in rats. Dev Psychobiol 16 (1983) 83-109
48. Tarazi F.I., Tomasini E.C., and Baldessarini R.J. Postnatal development of dopamine D1-like receptors in rat cortical and striatolimbic brain regions: An autoradiographic study. Dev Neurosci 21 (1999) 43-49
49. Teicher M.H., Barber N.I., Gelbard H.A., Gallitano A.L., Campbell A., Marsh E., and Baldessarini R.J. Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol. Neuropsychopharmacology 9 (1993) 147-156
50. Tunbridge E.M., Bannerman D.M., Sharp T., and Harrison P.J. COMT inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. J Neurosci 24 (2004) 5331-5335
51. Wang Y., Chan G.L.Y., Holden J.E., Dobko T., Mak E., Schulzer M., et al. Age-dependent decline of dopamine D1 receptors in human brain: A PET study. Synapse 30 (1998) 56-61
52. Volkow N.D., Gur R.C., Wang G.J., Fowler J.S., Moberg P.J., Ding Y.S., et al. Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals. Am J Psychiatry 155 (1998) 344-349
53. Wechsler D. Wechsler Intelligence Scale for Children-Third Edition (1991), Psychological Corporation, San Antonio, TX
54. Wechsler D. Wechsler Adult Intelligence Scale-Third Edition (1997), Psychological Corporation, San Antonio, TX
55. Wechsler D. Wechsler Memory Scale-Third Edition (1997), Psychological Corporation, San Antonio, TX
56. Weinshilboum R.M., Otterness D.M., and Szumlanski C.L. Methylation pharmacogenetics: Catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase. Annu Rev Pharmacol Toxicol 39 (1999) 19-52
57. Weinshilboum R.M., and Raymond F.A. Inheritance of low erythrocyte catechol-o-methyltransferase activity in man. Am J Hum Genet 29 (1977) 125-135
58. Williams G.V., and Goldman-Rakic P.S. Modulation of memory fields by dopamine D1 receptors in prefrontal cortex. Nature 376 (1995) 572-575
59. Yang Y.K., Chiu N.T., Chen C.C., Chen M., Yeh T.L., and Lee I.H. Correlation between fine motor activity and striatal dopamine D2 receptor density in patients with schizophrenia and healthy controls. Psychiatry Res Neuroimaging 123 (2003) 191-197
60. Yang Y.K., Yeh T.L., Chiu N.T., Lee I.H., Chen P.S., Lee L., and Jeffries K.J. Association between cognitive performance and striatal dopamine binding is higher in timing and motor tasks in patients with schizophrenia. Psychiatry Res Neuroimaging 131 (2004) 209-216