Linkage study of Catechol-O-Methyltransferase and attention-deficit hyperactivity disorder

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 88, Issue 6, 1999, Pages 710-713

  Barr, Cathy L ^a,b   Wigg, Karen ^a   Malone, Molly ^b   Schachar, Russell ^b   Tannock, Rosemary ^b   Roberts, Wendy ^b   Kennedy, James L ^c  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Attention deficit hyperactivity disorder; Catechol O Methyltransferase; Genetics; Transmission Disequilibrium Test

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; CHROMOSOME 22Q; DNA DETERMINATION; ENZYME ANALYSIS; FEMALE; GENETIC LINKAGE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOLECULAR GENETICS; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ALLELES; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CATECHOL O-METHYLTRANSFERASE; CHILD; CONTINENTAL POPULATION GROUPS; EUROPE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE (GENETICS); MALE; NUCLEAR FAMILY; ONTARIO; POLYMORPHISM, GENETIC;

EID: 0033573227     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19991215)88:6<710::AID-AJMG23>3.0.CO;2-Q     Document Type: Article

References (29)

1. Boudikova B, Szumlanski C, Maidak B, Weinshilboum R. 1990. Human liver catechol-O-methyltransferase pharmacogenetics. Clin Pharmacol Ther 48:381-389.
2. Boyle MH, Offord DR, Racine Y, Fleming JE, Szatmari P, Sanford M. 1993. Evaluation of the revised Ontario Child Health Study scales. J Child Psychol Psychiatry 34:189-213.
3. Carlson C, Papolos D, Pandita RK, Faedda GL, Veit S, Goldberg R, Shprintzen R, et al. 1997. Molecular analysis of velo-cardio-facial syndrome patients with psychiatric disorders. Am J Hum Genet 60:851-859.
4. Conners CK, Wells KC, Parker JD, Sitarenios G, Diamond JM, Powell JW. 1997. A new self-report scale for assessment of adolescent psychopathology: factor structure, reliability, validity, and diagnostic sensitivity. J Abnorm Child Psychol 25:487-497.
5. Daniels JK, Williams NM, Williams J, Jones LA, Cardno AG, Murphy KC, Spurlock G, et al. 1996. No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity. Am J Psychiatry 153:268-270.
6. Gogos JA, Morgan M, Luine V, Santha M, Ogawa S, Pfaff D, Karayiorgou M. 1998. Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci USA 95:9991-9996.
7. Grossman MH, Emanuel BS, Budarf ML. 1992. Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2. Genomics 12:822-825.
8. Karayiorgou M, Altemus M, Galke BL, Goldman D, Murphy DL, Ott J, Gogos JA. 1997. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci USA 94:4572-4575.
9. Karayiorgou M, Gogos JA, Galke BL, Wolyniec PS, Nestadt G, Antonarakis SE, Kazazian HH, et al. 1998. Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility. Biol Psychiatry 43:425-431.
10. Kirov G, Murphy KC, Arranz MJ, Jones I, McCandles F, Kunugi H, Murray RM, et al. 1998. Low activity allele of catechol-O-methyltransferase gene associated with rapid cycling bipolar disorder. Mol Psychiatry 3:342-345.
11. Kovacs M. 1995. "Manual: The Children's Depression Inventory." Toronto: Multi-health Systems.
12. Lachman HM, Morrow B, Shprintzen R, Veit S, Parsia SS, Faedda G, Goldberg R, et al. 1996. Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome. Am J Med Genet 67:468-472.
13. Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM. 1996. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6:243-250.
14. Levy F, Barr C, Sunohara G. 1998. Directions of aetiologic research on attention deficit hyperactivity disorder. Aust NZJ Psychiatry 32:97-103.
15. Li T, Vallada H, Curtis D, Arranz M, Xu K, Cai G, Deng H, et al. 1997. Catechol-O-methyltransferase Val158Met polymorphism: frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar affective disorder. Pharmacogenetics 7:349-353.
16. Lotta T, Vidgren J, Tilgmann C, Ulmanen I, Melen K, Julkunen I, Taskinen J. 1995. Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 34:4202-4210.
17. Malone MA, Kershner JR, Swanson JM. 1994. Hemispheric processing and methylphenidate effects in attention-deficit hyperactivity disorder. J Child Neurol 9:181-189.
18. McLeod HL, Syvanen AC, Githang'a J, Indalo A, Ismail D, Dewadr K, Ulmanen I, et al. 1998. Ethnic differences in catechol O-methyltransferase pharmacogenetics: frequency of the codon 108/158 low activity allele is lower in Kenyan than Caucasian or Southwest Asian individuals. Pharmacogenetics 8:195-199.
19. Miller SA, Dykes DD, Polesky HF. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215.
20. Ohara K, Nagai M, Suzuki Y, Ohara K. 1998. Low activity allele of catechol-O-methyltransferase gene and Japanese unipolar depression. Neuroreport 9:1305-1308.
21. Reynolds CR, Richmond BO. 1985. "What I Think and Feel (RCMAS)." Los Angeles, CA: Western Psychological Services.
22. Scambler PJ, Kelly D, Lindsay E, Williamson R, Goldberg R, Shprintzen R, Wilson DI, et al. 1992. Velo-cardio-facial syndrome associated with chromosome 22 deletions encompassing the DiGeorge locus. Lancet 339:1138-1139.
23. Semel E, Wing E, Secord W. 1995. "Clinical Evaluation of Language Fundamentals. 3rd ed. (CELF-3)." San Antonio, TX: The Psychological Corporation.
24. Sham PC, Curtis D. 1995. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet 59:323-336.
25. Solanto MV. 1998. Neuropsychopharmacological mechanisms of stimulant drug action in attention-deficit hyperactivity disorder: a review and integration. Behav Brain Res 94:127-152.
26. Spielman RS, McGinnis RE, Ewens WJ. 1993. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516.
27. Szatmari P, Offord DR, Boyle MH. 1989. Ontario Child Health Study: prevalence of attention deficit disorder with hyperactivity. J Child Psychol Psychiatry 30:219-230.
28. Wechsler DI. 1991. Examiner's Manual: Wechsler Intelligence Scale for Children. 3rd ed. New York: The Psychological Corporation.
29. Wilkinson GS. 1993. Wide Range Achievement Test 3 - Revision 3. Wilmington, DE: Jastak Associates.