Repeat MALDI MS imaging of a single tissue section using multiple matrices and tissue washes

Analytical and Bioanalytical Chemistry

Volumn 405, Issue 14, 2013, Pages 4719-4728

  Steven, Rory T ^a   Bunch, Josephine ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Lipid; MALDI; Mass spectrometry imaging; Protein; Tandem mass spectrometry

Indexed keywords

LIPIDS; MASS SPECTROMETRY; MOLECULAR IMAGING; PROTEINS; TISSUE;

COLLISION INDUCED DISSOCIATION; CYANO-4-HYDROXYCINNAMIC ACIDS; MALDI; MASS-SPECTROMETRY IMAGING; MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY; PARA-NITROANILINE (PNA); STRUCTURAL CHARACTERIZATION; TANDEM MASS SPECTROMETRY;

TISSUE ENGINEERING;

4-NITROANILINE; ALPHA-CYANO-4-HYDROXYCINNAMATE; ANILINE DERIVATIVE; COUMARIC ACID; LIPID; NERVE PROTEIN; PRESERVATION SOLUTION; 4 NITROANILINE; ALPHA CYANO 4 HYDROXYCINNAMIC ACID;

ANIMAL; BRAIN LEVEL; CHEMISTRY; IN VITRO STUDY; MASS SPECTROMETRY; MOUSE; ORGAN PRESERVATION; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; ARTICLE; METHODOLOGY;

ANILINE COMPOUNDS; ANIMALS; BRAIN CHEMISTRY; COUMARIC ACIDS; IN VITRO TECHNIQUES; LIPIDS; MICE; NERVE TISSUE PROTEINS; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84891666178     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-6899-9     Document Type: Article

References (46)

1. Bunch J, Clench MR, Richards DS (2004) Determination of pharmaceutical compounds in skin by imaging matrix-assisted laser desorption/ionisation mass spectrometry. Rapid Commun Mass Spectrom 18(24):3051-3060. doi:10.1002/rcm.1725
2. Cornett DS, Frappier SL, Caprioli RM (2008) MALDI-FTICR imaging mass spectrometry of drugs and metabolites in tissue. Anal Chem 80(14):5648-5653
3. Crecelius AC, Cornett DS, Caprioli RM, Williams B, Dawant BM, Bodenheimer B (2005) Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry. J Am Soc Mass Spectrom 16(7):1093-1099
4. Balluff B, Rauser S, Meding S, Elsner M, Schöne C, Feuchtinger A, Schuhmacher C, Novotny A, Jütting U, Maccarrone G (2011) MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer. Am J Pathol 179:2720-2729
5. Guenther S, Römpp A, Kummer W, Spengler B (2011) APMALDI imaging of neuropeptides in mouse pituitary gland with 5 μm spatial resolution and high mass accuracy. Int J Mass Spectrom 305(2):228-237
6. Stoeckli M, Staab D, Staufenbiel M, Wiederhold KH, Signor L (2002) Molecular imaging of amyloid β peptides in mouse brain sections using mass spectrometry. Anal Biochem 311(1):33-39
7. Vidová V, Pól J, Volný M, Novák P, Havlíček V, Wiedmer SK, Holopainen JM (2010) Visualizing spatial lipid distribution in porcine lens by MALDI imaging high-resolution mass spectrometry. J Lipid Res 51(8):2295-2302
8. Cerruti CD, Benabdellah F, Laprévote O, Touboul D, Brunelle A (2012) MALDI imaging and structural analysis of rat brain lipid negative ions with 9-aminoacridine matrix. Anal Chem 84(5):2164-2171
9. Palmer AD, Griffiths R, Styles I, Claridge E, Calcagni A, Bunch J (2012) Sucrose cryo-protection facilitates imaging of whole eye sections by MALDI mass spectrometry. J Mass Spectrom 47(2):237-241
10. Angel PM, Spraggins JM, Baldwin HS, Caprioli R (2012) Enhanced sensitivity for high spatial resolution lipid analysis by negative ion mode matrix assisted laser desorption ionization imaging mass spectrometry. Anal Chem 84(3):1557-1564
11. Veloso A, Astigarraga E, Barreda-Gómez G, Manuel I, Ferrer I, Teresa Giralt M, Ochoa B, Fresnedo O, Rodríguez-Puertas R, Fernández JA (2011) Anatomical distribution of lipids in human brain cortex by imaging mass spectrometry. J Am Soc Mass Spectrom 22(2):329-338
12. Lanni EJ, Rubakhin SS, Sweedler JV (2012) Mass spectrometry imaging and profiling of single cells. J Proteomics 75:5036-5051
13. Stoeckli M, Staab D, Schweitzer A (2007) Compound and metabolite distribution measured by MALDI mass spectrometric imaging in whole-body tissue sections. Int J Mass Spectrom 260(2):195-202
14. Soltwisch J, Jaskolla TW, Hillenkamp FH, Karas M, Dreisewerd K (2012) Ion yields in UV-MALDI mass spectrometry as a function of excitation laser wavelength and optical and physico-chemical properties of classical and halogen-substituted MALDI matrixes. Anal Chem 84:6567-6576
15. Shanta SR, Zhou LH, Park YS, Kim YH, Kim Y, Kim KP (2011) Binary matrix for MALDI imaging mass spectrometry of phospholipids in both ion modes. Anal Chem 83(4):1252-1259
16. Luo G, Marginean I, Vertes A (2002) Internal energy of ions generated by matrix-assisted laser desorption/ionization. Anal Chem 74(24):6185-6190
17. Chernushevich IV, Loboda AV, Thomson BA (2001) An introduction to quadrupole-time-of-flight mass spectrometry. J Mass Spectrom 36(8):849-865
18. Yagnik GB, Korte AR, Lee YJ (2013) Multiplex mass spectrometry imaging for latent fingerprints. J Mass Spectrom 48(1):100-104
19. Perdian D, Lee YJ (2010) Imaging MS methodology for more chemical information in less data acquisition time utilizing a hybrid linear ion trap-orbitrap mass spectrometer. Anal Chem 82(22):9393-9400
20. Holle A, Haase A, Kayser M, Hohndorf J (2006) Optimizing UV laser focus profiles for improved MALDI performance. J Mass Spectrom 41(6):705-716. doi:10.1002/jms.1041
21. Clench MR, Trim PJ, Djidja MC, Atkinson SJ, Oakes K, Cole LM, Anderson DMG, Hart PJ, Francese S (2010) Introduction of a 20 kHz Nd:YVO4 laser into a hybrid quadrupole time-of-flight mass spectrometer for MALDI-MS imaging. Anal Bioanal Chem 397(8):3409-3419. doi:10.1007/s00216-010-3874-6
22. Wiegelmann M, Soltwisch J, Jaskolla TW, Dreisewerd K (2012) Matching the laser wavelength to the absorption properties of matrices increases the ion yield in UV-MALDI mass spectrometry. Anal Bioanal Chem [Epub ahead of print]
23. Chughtai S, Chughtai K, Pastor BC, Kiss A, Agrawal P, MacAleese L, Heeren R (2012) A multimodal mass spectrometry imaging approach for the study of musculoskeletal tissues. Int J Mass Spectrom 325-327:150-160
24. Matusch A, Fenn LS, Depboylu C, Klietz M, Strohmer S, McLean JA, Becker JS (2012) Combined elemental and biomolecular mass spectrometry imaging for probing the inventory of tissue at a micrometer scale. Anal Chem 84(7):3170-3178
25. Garrett TJ, Prieto-Conaway MC, Kovtoun V, Bui H, Izgarian N, Stafford G, Yost RA (2007) Imaging of small molecules in tissue sections with a new intermediate-pressure MALDI linear ion trap mass spectrometer. Int J Mass Spectrom 260(2):166-176
26. Eberlin LS, Liu X, Ferreira CR, Santagata S, Agar NYR, Cooks RG (2011) Desorption electrospray ionization then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections. Anal Chem 83(22):8366-8371
27. Seeley EH, Oppenheimer SR, Mi D, Chaurand P, Caprioli RM (2008) Enhancement of protein sensitivity for MALDI imaging mass spectrometry after chemical treatment of tissue sections. J Am Soc Mass Spectrom 19(8):1069-1077
28. Race AM, Styles IB, Bunch J (2012) Inclusive sharing of mass spectrometry imaging data requires a converter for all. J Proteomics 75(16):5111-5112. doi:10.1016/j.jprot.2012.05.035
29. Jurchen JC, Rubakhin SS, Sweedler JV (2005)MALDI-MS imaging of features smaller than the size of the laser beam. J Am Soc Mass Spectrom 16(10):1654-1659. doi:10.1016/j.jasms.2005.06.006
30. Simmons DA (2008) Improved MALDI-MS imaging performance using continuous laser rastering. Applied Biosystems Technical Note
31. Steven RT, Race AM, Bunch J (2013) para-Nitroaniline is a promising matrix for MALDI-MS imaging on intermediate pressure MS systems. J Am Soc Mass Spectrom. doi:10.1007/s13361-013-0586-0
32. Jackson SN, Ugarov M, Post JD, Egan T, Langlais D, Schultz JA, Woods AS (2008) A study of phospholipids by ion mobility TOFMS. J Am Soc Mass Spectrom 19(11):1655-1662
33. Fournier I, Beavis R, Blais J, Tabet J, Bolbach G (1997) Hysteresis effects observed in MALDI using oriented, protein-doped matrix crystals. Int J Mass Spectrom Ion Process 169:19-29
34. Fournier I, Tabet JC, Bolbach G (2002) Irradiation effects in MALDI and surface modifications: part I: sinapinic acid monocrystals. Int J Mass Spectrom 219(3):515-523
35. Fournier I, Marinach C, Tabet JC, Bolbach G (2003) Irradiation effects in MALDI, ablation, ion production, and surface modifications. Part II: 2,5-dihydroxybenzoic acid monocrystals. J Am Soc Mass Spectrom 14(8):893-899. doi:10.1016/S1044-0305(03) 00347-7
36. Tarzi OI, Nonami H, Erra-Balsells R (2009) The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2, 5-dihydroxybenzoic acid, 2, 4, 6-trihydroxyacetophenone, α-cyano-4-hydroxycinnamic acid, 3, 5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane. J Mass Spectrom 44(2):260-277
37. Wang HYJ, Liu CB, Wu HW, Kuo JS (2010) Direct profiling of phospholipids and lysophospholipids in rat brain sections after ischemic stroke. Rapid Commun Mass Spectrom 24(14):2057-2064
38. Amstalden van Hove ER, Smith DF, Heeren R (2010) A concise review of mass spectrometry imaging. J Chromatogr A 1217(25):3946-3954
39. Al-Saad KA, Siems WF, Hill H, Zabrouskov V, Knowles NR (2003) Structural analysis of phosphatidylcholines by post-source decay matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. J Am Soc Mass Spectrom 14(4):373-382
40. Stübiger G, Belgacem O (2007) Analysis of lipids using 2, 4, 6-trihydroxyacetophenone as a matrix for MALDI mass spectrometry. Anal Chem 79(8):3206-3213
41. Carter CL, McLeod CW, Bunch J (2011) Imaging of phospholipids in formalin fixed rat brain sections by matrix assisted laser desorption/ ionization mass spectrometry. J Am Soc Mass Spectrom 22(11):1991-1998
42. Prideaux B, Dartois V, Staab D, Weiner DM, Goh A, Via LE, Barry CE III, Stoeckli M (2011) High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions. Anal Chem 83(6):2112-2118
43. Khatib-Shahidi S, Andersson M, Herman JL, Gillespie TA, Caprioli RM (2006) Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Anal Chem 78(18):6448-6456
44. Alzate O (2009) Neuroproteomics. CRC, Boca Raton
45. Shrivas K, Hayasaka T, Goto-Inoue N, Sugiura Y, Zaima N, Setou M (2010) Ionic matrix for enhanced MALDI imaging mass spectrometry for identification of phospholipids in mouse liver and cerebellum tissue sections. Anal Chem 82(21):8800-8806
46. Zemski Berry KA, Hankin JA, Barkley RM, Spraggins JM, Caprioli RM, Murphy RC (2011) MALDI imaging of lipid biochemistry in tissues by mass spectrometry. Chem Rev 111(10):6491-6512. doi:10.1021/cr200280p