-
1
-
-
52749085896
-
Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis
-
Wurfel MM, GordonAC,Holden TD, et al. Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis. Am J Respir Crit Care Med. 2008;178:710-720.
-
(2008)
Am J Respir Crit Care Med.
, vol.178
, pp. 710-720
-
-
Wurfel, M.M.1
Gordon, A.C.2
Holden, T.D.3
-
2
-
-
0036097720
-
The G->a single nucleotide polymorphism at the -308 position in the tumor necrosis factor-Alpha promoter increases the risk for severe sepsis after trauma
-
O'Keefe GE, Hybki DL, Munford RS. The G->a single nucleotide polymorphism at the -308 position in the tumor necrosis factor-Alpha promoter increases the risk for severe sepsis after trauma. J Trauma. 2002;52:817-825.
-
(2002)
J Trauma.
, vol.52
, pp. 817-825
-
-
O'Keefe, G.E.1
Hybki, D.L.2
Munford, R.S.3
-
3
-
-
59449097257
-
Tumor necrosis factor gene variation and the risk of mortality after burn injury: A cohort study
-
Shalhub S, Pham TN, Gibran NS, et al. Tumor necrosis factor gene variation and the risk of mortality after burn injury: A cohort study. J Burn Care Res. 2009;30:105-111.
-
(2009)
J Burn Care Res.
, vol.30
, pp. 105-111
-
-
Shalhub, S.1
Pham, T.N.2
Gibran, N.S.3
-
4
-
-
8744301714
-
TLR4 and TNF-Alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury
-
Barber RC, Aragaki CC, Rivera-Chavez FA, et al. TLR4 and TNF-Alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury. J Med Genet. 2004;41:808-813.
-
(2004)
J Med Genet.
, vol.41
, pp. 808-813
-
-
Barber, R.C.1
Aragaki, C.C.2
Rivera-Chavez, F.A.3
-
5
-
-
0032200809
-
Genetic component in the inflammatory response induced by bacterial lipopolysaccharide
-
De Maio A, Mooney ML, Matesic LE, et al. Genetic component in the inflammatory response induced by bacterial lipopolysaccharide. Shock. 1998;10:319-323.
-
(1998)
Shock.
, vol.10
, pp. 319-323
-
-
De Maio, A.1
Mooney, M.L.2
Matesic, L.E.3
-
6
-
-
0029922017
-
A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-Alpha concentrations and outcome of patients with severe sepsis
-
Stuber F, Petersen M, Bokelmann F, et al. A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-Alpha concentrations and outcome of patients with severe sepsis. Crit Care Med. 1996;24:381-384.
-
(1996)
Crit Care Med.
, vol.24
, pp. 381-384
-
-
Stuber, F.1
Petersen, M.2
Bokelmann, F.3
-
7
-
-
84155171255
-
A functional variant of lipopolysaccharide binding protein predisposes to sepsis and organ dysfunction in patients with major trauma
-
Zeng L, Gu W, Zhang AQ, et al. A functional variant of lipopolysaccharide binding protein predisposes to sepsis and organ dysfunction in patients with major trauma. Ann Surg. 2012;255:147-157.
-
(2012)
Ann Surg.
, vol.255
, pp. 147-157
-
-
Zeng, L.1
Gu, W.2
Zhang, A.Q.3
-
8
-
-
67649194968
-
Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: A cohort study
-
Shalhub S, Junker CE, Imahara SD, et al.Variation in the TLR4 gene influences the risk of organ failure and shock posttrauma: A cohort study. J Trauma. 2009;66:115-122.
-
(2009)
J Trauma.
, vol.66
, pp. 115-122
-
-
Shalhub, S.1
Junker, C.E.2
Imahara, S.D.3
-
9
-
-
77955383770
-
DAMPening inflammation by modulating TLR signalling
-
Piccinini AM, Midwood KS. DAMPening inflammation by modulating TLR signalling. Mediators Inflamm. 2010;2010.
-
(2010)
Mediators Inflamm.
, vol.2010
-
-
Piccinini, A.M.1
Midwood, K.S.2
-
10
-
-
78649335026
-
The role of toll-like receptors in acute and chronic lung inflammation
-
Lafferty EI, Qureshi ST, Schnare M. The role of toll-like receptors in acute and chronic lung inflammation. J Inflamm (Lond). 2010;7:57.
-
(2010)
J Inflamm (Lond)
, vol.7
, pp. 57
-
-
Lafferty, E.I.1
Qureshi, S.T.2
Schnare, M.3
-
11
-
-
77950817867
-
Early release of high mobility group box nuclear protein 1 after severe trauma in humans: Role of injury severity and tissue hypoperfusion
-
Cohen MJ, Brohi K, Calfee CS, et al. Early release of high mobility group box nuclear protein 1 after severe trauma in humans: Role of injury severity and tissue hypoperfusion. Crit Care. 2009;13:R174.
-
(2009)
Crit Care.
, vol.13
-
-
Cohen, M.J.1
Brohi, K.2
Calfee, C.S.3
-
12
-
-
33749019109
-
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock
-
Yang R, Harada T, Mollen KP, et al. Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock. Mol Med. 2006;12:105-114.
-
(2006)
Mol Med.
, vol.12
, pp. 105-114
-
-
Yang, R.1
Harada, T.2
Mollen, K.P.3
-
13
-
-
0036644042
-
Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
Takeuchi O, Sato S, Horiuchi T, et al. Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol. 2002;169:10-14.
-
(2002)
J Immunol.
, vol.169
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
-
14
-
-
34447108077
-
Triacylated lipoproteins derived from Mycoplasma pneumoniae activate nuclear factor-kappaB through toll-like receptors 1 and 2
-
Shimizu T, Kida Y, Kuwano K. Triacylated lipoproteins derived from Mycoplasma pneumoniae activate nuclear factor-kappaB through toll-like receptors 1 and 2. Immunology. 2007;121:473-483.
-
(2007)
Immunology.
, vol.121
, pp. 473-483
-
-
Shimizu, T.1
Kida, Y.2
Kuwano, K.3
-
15
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The Accp/sccm consensus conference committee. American college of chest physicians/society of critical care medicine
-
Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992;101:1644-1655.
-
(1992)
Chest.
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
-
16
-
-
34247235247
-
Acute kidney injury network: Report of an initiative to improve outcomes in acute kidney injury
-
Mehta RL, Kellum JA, Shah SV, et al. Acute Kidney Injury Network: Report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11:R31.
-
(2007)
Crit Care.
, vol.11
-
-
Mehta, R.L.1
Kellum, J.A.2
Shah, S.V.3
-
17
-
-
0033006003
-
Allelic discrimination using fluorogenic probes and the 5' nuclease assay
-
Livak KJ. Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet Anal. 1999;14:143-149.
-
(1999)
Genet Anal.
, vol.14
, pp. 143-149
-
-
Livak, K.J.1
-
18
-
-
31744435871
-
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
-
Skol AD, Scott LJ, Abecasis GR, et al. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet. 2006;38:209-213.
-
(2006)
Nat Genet.
, vol.38
, pp. 209-213
-
-
Skol, A.D.1
Scott, L.J.2
Abecasis, G.R.3
-
19
-
-
0034671803
-
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses
-
Wyllie DH, Kiss-Toth E, Visintin A, et al. Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses. J Immunol. 2000;165:7125-7132.
-
(2000)
J Immunol.
, vol.165
, pp. 7125-7132
-
-
Wyllie, D.H.1
Kiss-Toth, E.2
Visintin, A.3
-
21
-
-
80055098323
-
Deaths: Leading causes for 2007
-
Heron M. Deaths: Leading causes for 2007. Natl Vital Stat Rep. 2011;59:1-95.
-
(2011)
Natl Vital Stat Rep.
, vol.59
, pp. 1-95
-
-
Heron, M.1
-
22
-
-
79953223257
-
Epidemiology and risk factors of sepsis after multiple trauma: An analysis of 29,829 patients from the trauma registry of the german society for trauma surgery
-
Wafaisade A, Lefering R, Bouillon B, et al. Epidemiology and risk factors of sepsis after multiple trauma: An analysis of 29,829 patients from the Trauma Registry of the German Society for Trauma Surgery. Crit Care Med. 2011;39:621-628.
-
(2011)
Crit Care Med.
, vol.39
, pp. 621-628
-
-
Wafaisade, A.1
Lefering, R.2
Bouillon, B.3
-
23
-
-
34548618251
-
Sequence variability and protein domain architectures for bovine Toll-like receptors 1, 5, and 10
-
Seabury CM, Cargill EJ, Womack JE. Sequence variability and protein domain architectures for bovine Toll-like receptors 1, 5, and 10. Genomics. 2007;90:502-515.
-
(2007)
Genomics
, vol.90
, pp. 502-515
-
-
Seabury, C.M.1
Cargill, E.J.2
Womack, J.E.3
-
24
-
-
77951640946
-
A method and server for predicting damaging missense mutations
-
Adzhubei IA, Schmidt S, Peshkin L, et al. A method and server for predicting damaging missense mutations. Nat Methods. 2010;7:248-249.
-
(2010)
Nat Methods.
, vol.7
, pp. 248-249
-
-
Adzhubei, I.A.1
Schmidt, S.2
Peshkin, L.3
-
25
-
-
0035026704
-
Predicting deleterious amino acid substitutions
-
Ng PC, Henikoff S. Predicting deleterious amino acid substitutions. Genome Res. 2001;11:863-874.
-
(2001)
Genome Res.
, vol.11
, pp. 863-874
-
-
Ng, P.C.1
Henikoff, S.2
-
26
-
-
77957654090
-
Leprosy and the adaptation of human toll-like receptor 1
-
Wong SH, Gochhait S, Malhotra D, et al. Leprosy and the adaptation of human toll-like receptor 1. PLoS Pathog. 2010;6:e1000979.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Wong, S.H.1
Gochhait, S.2
Malhotra, D.3
-
27
-
-
67650105333
-
Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women
-
Hawn TR, Scholes D, Li SS, et al. Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. PLoS One. 2009;4: E5990.
-
(2009)
PLoS One
, vol.4
-
-
Hawn, T.R.1
Scholes, D.2
Li, S.S.3
-
28
-
-
78149419608
-
Common variants of TLR1 associate with organ dysfunction and sustained pro-inflammatory responses during sepsis
-
Pino-Yanes M, Corrales A, Casula M, et al. Common variants of TLR1 associate with organ dysfunction and sustained pro-inflammatory responses during sepsis. PLoS One. 2010;5:e13759.
-
(2010)
PLoS One.
, vol.5
-
-
Pino-Yanes, M.1
Corrales, A.2
Casula, M.3
-
29
-
-
77954027299
-
The toll-like receptor 1 variant S248N influences placental malaria
-
Hamann L, Bedu-Addo G, Eggelte TA, et al. The toll-like receptor 1 variant S248N influences placental malaria. Infect Genet Evol. 2010;10:785-789.
-
(2010)
Infect Genet Evol.
, vol.10
, pp. 785-789
-
-
Hamann, L.1
Bedu-Addo, G.2
Eggelte, T.A.3
-
30
-
-
79952132519
-
Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: A case-control study in the Korean population
-
Lee JS, Park HK, Suh JS, et al. Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: A case-control study in the Korean population. Int J Immunogenet. 2011;38:133-138.
-
(2011)
Int J Immunogenet.
, vol.38
, pp. 133-138
-
-
Lee, J.S.1
Park, H.K.2
Suh, J.S.3
-
31
-
-
46049084570
-
Toll-like receptor heterodimer variants protect from childhood asthma
-
92 e81-e88
-
KormannMS, DepnerM, Hartl D, et al. Toll-like receptor heterodimer variants protect from childhood asthma. J Allergy Clin Immunol. 2008;122:86-92, 92. e81- e88.
-
(2008)
J Allergy Clin Immunol.
, vol.122
, pp. 86-92
-
-
Kormann, M.S.1
Depner, M.2
Hartl, D.3
-
32
-
-
35448943896
-
Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer
-
Chen YC, Giovannucci E, Kraft P, et al. Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2007;16:1982-1989.
-
(2007)
Cancer Epidemiol Biomarkers Prev.
, vol.16
, pp. 1982-1989
-
-
Chen, Y.C.1
Giovannucci, E.2
Kraft, P.3
|