Tumor necrosis factor gene variation and the bisk of mortality after burn injury: A cohort study

Journal of Burn Care and Research

Volumn 30, Issue 1, 2009, Pages 105-111

  Shalhub, Sherene ^a   Pham, Tarn N ^a   Gibran, Nicole S ^a   O'Keefe, Grant E ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ALLELE; ARTICLE; BLOOD SAMPLING; BURN; CONTROLLED STUDY; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; INFLAMMATION; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; RISK FACTOR; SEPTIC SHOCK; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; AREA UNDER CURVE; BURNS; CHI-SQUARE DISTRIBUTION; COHORT STUDIES; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; INJURY SEVERITY SCORE; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; ROC CURVE; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 59449097257     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0b013e3181921f60     Document Type: Article

References (40)

1. Latenser BA, Miller SF, Bessey PQ, et al. National Burn Repository 2006: a ten-year review. J Burn Care Res 2007;28: 635-58.
2. 2.O'Keefe GE, Hunt JL, Purdue GF. An evaluation of risk factors for mortality after bum trauma and the identification of gender-dependent differences in outcomes. J Am Coll Surg 2001;192:153-60.
3. McGwin G Jr, George RL, Cross JM, Rue LW. Improving the ability to predict mortality among burn patients. Burns 2008;34:320-7.
4. Kerby JD, McGwin G Jr, George RL, Cross JA, Chaudry IH, Rue LW 3rd. Sex differences in mortality after burn injury: results of analysis of the National Burn Repository of the American Burn Association. J Burn Care Res 2006;27: 452-6.
5. Zhao Z, Zhang F. Sequence context analysis of 8.2 million single nucleotide polymorphisms in the human genome. Gene 2006;366:316-24.
6. Cobb JP, O'Keefe GE. Injury research in the genomic era. Lancet 2004;363:2076-83.
7. Brookes AJ. The essence of SNPs. Gene 1999;234: 177-86.
8. Mira JP, Cariou A, Grail F, et al. Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. JAMA 1999; 282:561-8.
9. O'Keefe GE, Hybki DL, Munford RS. The G->A single nucleotide polymorphism at the - 308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma. J Trauma 2002;52:817-25.
10. Menges T, Konig IR, Hossain H, et al. Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor. Crit Care Med 2008; 36:1456-62.
11. Heesen M, Obertacke U, Schade FU, Bloemeke B, Majetschak M. The interleukin-6 G( -174)C polymorphism and the ex vivo interleukin-6 response to endotoxin in severely injured blunt trauma patients. Eur Cytokine Netw 2002;13:72-7.
12. Rivera-Chavez FA, Peters-Hybki DL, Barber RC, O'Keefe GE. Interleukin-6 promoter haplotypes and interleukin-6 cytokine responses. Shock 2003;20:218-23.
13. Arnalich F, Lopez-Maderuelo D, Codoceo R, et al. Interleukin- 1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis. Clin Exp Immunol 2002;127: 331-6.
14. Barber RC, Aragaki CC, Chang LY, et al. CD14-159 C allele is associated with increased risk of mortality after burn injury. Shock 2007;27:232-7.
15. Schwacha MG, Holland LT, Chaudry IH, Messina JL. Genetic variability in the immune-inflammatory response after major burn injury. Shock 2005;23:123-8.
16. Lin J, Yao YM, Huang ZH, et al. [The influence of CD 14 genomic polymorphism on CD14 gene expression as well as protein release and its clinical significance in patients with extensive burns.] Zhonghua Wai Ke Za Zhi 2006;44: 907-10.
17. Barber RC, Chang LY, Arnoldo BD, et al. Innate immunity SNPs are associated with risk for severe sepsis after burn injury. Clin Med Res 2006;4:250-5.
18. Greenhalgh DG, Saffle JR, Holmes JH, et al. American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res 2007;28:776-90.
19. Smith DL, Cairns BA, Ramadan F, et al. Effect of inhalation injury, burn size, and age on mortality: a study of 1447 consecutive burn patients. J Trauma 1994;37:655-9.
20. Jeschke MG, Mlcak RP, Finnerty CC, et al. Burn size determines the inflammatory and hypermetabolic response. Crit Care 2007;11:R90.
21. Kroeger KM, Abraham LJ. Identification of an AP-2 element in the -323 to -285 region of the TNF-alpha gene. Biochem Mol Biol Int 1996;40:43-51.
22. Hajeer AH, Hutchinson TV. TNF-alpha gene polymorphism: clinical and biological implications. Microsc Res Tech 2000; 50:216-28.
23. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 1997;94:3195-9.
24. Louis E, Franchimont D, Piron A, et al. Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans. Clin Exp Immunol 1998;113:401-6.
25. Heesen M, Kunz D, Bachmann-Mennenga B, Merk HF, BlDemeke B. Linkage disequilibrium between tumor necrosis factor (TNF)-alpha -308 G/A promoter and TNF- beta Ncol polymorphisms: association with TNF-alpha response of granulocytes to endotoxin stimulation. Crit Care Med 2003;31:211-4.
26. Lee YH, Rho YH, Choi SJ, Ji JD, Song GG. Association of TNF-alpha - 308 G/A polymorphism with responsiveness to TNF-alpha-blockers in rheumatoid arthritis: a meta-analysis. Rheumatol Int 2006;27:157-61.
27. Lee YH, Harley JB, Nath SK. Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. Eur J Hum Genet 2006;14:364-71.
28. Dianliang Z, Jieshou L, Zhiwei J, Baojun Y. Association of plasma levels of tumor necrosis factor (TNF)-alpha and its soluble receptors, two polymorphisms of the TNF gene, with acute severe pancreatitis and early septic shock due to it. Pancreas 2003;26:339-43.
29. Tang GJ, Huang SL, Yien HW, et al. Tumor necrosis factor gene polymorphism and septic shock in surgical infection. Crit Care Med 2000;28:2733-6.
30. Appoloni O, Dupont E, Vandercruys M, Andriens M, Duchateau J, Vincent JL. Association of tumor necrosis factor-2 allele with plasma tumor necrosis factor-alpha levels and mortality from septic shock. Am J Med 2001;110: 486-8.
31. Gordon AC, Lagan AL, Aganna E, et al. TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study. Genes Immun 2004;5:631-40.
32. Kovar FM, Marsik C, Cvitko T, Wagner OF, Jilma B, Endler G. The tumor necrosis factor alpha -308 G/A polymorphism does not influence inflammation and coagulation response in human endotoxemia. Shock 2007;27:238-41.
33. Zhang B, Huang YH, Chen Y, Yang Y, Hao ZL, Xie SL. Plasma tumor necrosis factor-alpha, its soluble receptors and interleukin-1 beta levels in critically burned patients. Burns 1998;24:599-603.
34. Marano MA, Fong Y, Moldawer LL, et al. Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality. Surg Gynecol Obstet 1990;170:32-8.
35. Sheridan RL, Ryan CM, Yin LM, Hurley J, Tompkins RG. Death in the burn unit: sterile multiple organ failure. Burns 1998;24:307-11.
36. Ioannidis JP, Trikalinos TA, Ntzani EE, Contopoulos-Ioannidis DG. Genetic associations in large versus small studies: an empirical assessment. Lancet 2003;361:567-71.
37. Klein MB, Silver G, Gamelli RL, et al. Inflammation and the host response to injury: an overview of the multicenter study of the genomic and proteomic response to burn injury. J Burn Care Res 2006;27:448-51.
38. Palmieri TL, Caruso DM, Foster KN, et al. Effect of blood transfusion on outcome after major burn injury: a multicenter study. Crit Care Med 2006;34:1602-7.
39. Wolf SE, Edelman LS, Kemalyan N, et al. Effects of oxandrolone on outcome measures in the severely burned: a multicenter prospective randomized double-blind trial. J Burn Care Res 2006;27:131-9.
40. Nadel S, Newport MJ, Booy R, Levin M. Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease. J Infect Dis 1996;174:878-80.