Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABAA receptors

European Neuropsychopharmacology

Volumn 23, Issue 5, 2013, Pages 390-399

  Joksimović, Srdan ^a,b   Divljaković, Jovana ^b   Van Linn, Michael L ^c   Varagic, Zdravko ^d   Brajković, Gordana ^e   Milinković, Marija M ^b   Yin, Wenyuan ^c   Timić, Tamara ^b   Sieghart, Werner ^d   Cook, James M ^c   Savić, Miroslav M ^b  

^a Medicines and Medical Devices Agency of Serbia   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e UNIVERSITY OF DEFENCE   (Serbia)

Author keywords

Diazepam; GABAA subtype selective ligand; Two electrode voltage clamp; Water maze

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 8 ETHYNYL BETA CARBOLINE 3 CARBOXYLIC ACID TERT BUTYL ESTER; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; BETA CARBOLINE 3 CARBOXYLIC ACID TERT BUTYL ESTER; DIAZEPAM; GABAERGIC RECEPTOR AFFECTING AGENT; LIGAND; PARTIAL AGONIST; UNCLASSIFIED DRUG; WYS 8; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; GABRA1 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BRAIN TISSUE; CONTROLLED STUDY; ELECTRODE; IN VITRO STUDY; LATENT PERIOD; LEARNING DISORDER; MALE; MORRIS WATER MAZE TEST; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; SPATIAL LEARNING; SPATIAL LEARNING DEFICIT; SPATIAL MEMORY; TREATMENT DURATION; VOLTAGE CLAMP TECHNIQUE; XENOPUS LAEVIS; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FEMALE; MAZE TEST; MEMORY DISORDER; PATHOPHYSIOLOGY; PHYSIOLOGY; SPATIAL BEHAVIOR; WISTAR RAT; CHEMICALLY INDUCED; DRUG EFFECTS; TOXICITY;

ANIMALS; BENZODIAZEPINES; FEMALE; GABA MODULATORS; MALE; MAZE LEARNING; MEMORY DISORDERS; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SPATIAL BEHAVIOR; XENOPUS LAEVIS;

EID: 84891597940     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2012.05.003     Document Type: Article

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