The differential role of α1- and α5- containing GABAA receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats

International Journal of Neuropsychopharmacology

Volumn 12, Issue 9, 2009, Pages 1179-1193

  Savić, Miroslav M ^a   Milinković, Marija M ^a   Rallapalli, Sundari ^b   Clayton, Terry ^b   Joksimović, Srãån ^c   Van Linn, Michael ^b   Cook, James M ^b  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c Medicines and Medical Devices Agency of Serbia   (Serbia)

Author keywords

Benzodiazepine; GABAA subtype; learning; memory; sedation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BETA CCT; DIAZEPAM; LIGAND; UNCLASSIFIED DRUG; XLI 093; 1,3 BIS(8 ETHYNYL 5,6 DIHYDRO 5 METHYL 6 OXO 4H IMIDAZO(1,5 A)(1,4)BENZODIAZEPINE 3 CARBOXY)PROPYL DIESTER; 1,3-BIS(8-ETHYNYL-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO(1,5-A)(1,4)BENZODIAZEPINE-3-CARBOXY)PROPYL DIESTER; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; BETA CARBOLINE 3 CARBOXYLIC ACID TERT BUTYL ESTER; CARBOLINE DERIVATIVE; GABRA1 PROTEIN, HUMAN; GABRA1 PROTEIN, RAT; GABRA5 PROTEIN, RAT; HYPNOTIC SEDATIVE AGENT; IMIDAZOLE DERIVATIVE; TERT-BUTYL BETA-CARBOLINE-3-CARBOXYLATE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CLINICAL ASSESSMENT; CLINICAL EXAMINATION; CLINICAL TRIAL; COGNITION; CONTROLLED STUDY; DECLARATIVE MEMORY; DRUG EFFECT; DRUG EFFICACY; HUMAN; LATENT PERIOD; LOCOMOTION; MALE; MAZE TEST; MEMORY; NONHUMAN; PERFORMANCE; PRIORITY JOURNAL; RAT; RECALL; SEDATION; TASK PERFORMANCE; ANIMAL; ANIMAL BEHAVIOR; AROUSAL; COMPARATIVE STUDY; DOSE RESPONSE; METABOLISM; MOTOR ACTIVITY; REACTION TIME; SWIMMING; TIME; WISTAR RAT;

ANIMALS; ANTI-ANXIETY AGENTS; AROUSAL; BEHAVIOR, ANIMAL; BENZODIAZEPINONES; CARBOLINES; COGNITION; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA AGONISTS; GABA ANTAGONISTS; GABA-A RECEPTOR AGONISTS; GABA-A RECEPTOR ANTAGONISTS; HYPNOTICS AND SEDATIVES; IMIDAZOLES; MALE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; RATS; RATS, WISTAR; REACTION TIME; RECEPTORS, GABA-A; SWIMMING; TIME FACTORS;

EID: 77649270051     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145709000108     Document Type: Article

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