A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure

Blood

Volumn 122, Issue 15, 2013, Pages 2562-2571

  Aronovich, Anna ^a   Nur, Yaniv ^a   Shezen, Elias ^a   Rosen, Chava ^a   Zlotnikov Klionsky, Yael ^a   Milman, Irit ^a   Yarimi, Liran ^a   Hagin, David ^a   Rechavi, Gidi ^b   Martinowitz, Uriel ^c   Nagasawa, Takashi ^d,e   Frenette, Paul S ^f   Tchorsh Yutsis, Dalit ^a   Reisner, Yair ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b Cancer Research Center   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

^d KYOTO UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; CD34 ANTIGEN; COLLAGEN; GRANULOCYTE COLONY STIMULATING FACTOR; NESTIN; OSTEOCALCIN; OSTEOPONTIN; PROTEINASE ACTIVATED RECEPTOR 1; STROMAL CELL DERIVED FACTOR 1; THROMBIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MASS; BONE STRUCTURE; CELL GROWTH; CHIMERA; COLONY FORMING UNIT C; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; FROZEN SECTION; HEMATOCRIT; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; IMMUNOFLUORESCENCE TEST; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN WEIGHT; SPLENOMEGALY; STROMA CELL; TIBIAL METAPHYSIS; ANIMAL; BLOOD CLOTTING; BONE; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; RADIOGRAPHY;

ANIMALS; BLOOD COAGULATION; BONE AND BONES; FACTOR VIII; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTOR, PAR-1; SIGNAL TRANSDUCTION; STROMAL CELLS; THROMBIN; X-RAY MICROTOMOGRAPHY;

EID: 84891550694     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-08-447458     Document Type: Article

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