Simplified captopril analogues as NDM-1 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 1, 2014, Pages 386-389

  Li, Ningning ^a,b   Xu, Yintong ^a,b   Xia, Qiang ^a,b   Bai, Cuigai ^b   Wang, Taiyi ^a,b   Wang, Lei ^a,b   He, Dingdi ^a,b   Xie, Nannan ^a,b   Li, Lixin ^b   Wang, Jing ^b   Zhou, Hong Gang ^a,b   Xu, Feng ^a,b   Yang, Cheng ^a,b   Zhang, Quan ^a   Yin, Zheng ^a,b   Guo, Yu ^a   Chen, Yue ^a,b  

^a NANKAI UNIVERSITY   (China)

^b Tianjin International Joint Academy of Biotechnology and Medicine   (China)

Author keywords

3 Mercapto 2 methylpropanoic acid; Captopril; Metalantidote; NDM 1 inhibitor

Indexed keywords

2 FLUORO BENZYL AMIDE; 2 HYDROXYL BENZYL AMIDE; 3 MERCAPTO 2 METHYLPROPANOIC ACID; 3 METHYL BENZYL AMIDE; AMIDE; ANTIDOTE; BENZYL AMIDE; BETA LACTAMASE INHIBITOR; BROMO THIOZOLE AMIDE; BUTYL AMIDE; CAPTOPRIL; HYDROXYLAMIDE DERIVATIVE; IMIDAZOLE; ISOBUTYRIC ACID; METAL; METHYL OXAZOLE AMIDE; METHYL SULFONYL ETHYL AMIDE; METHYL SULFYL ETHYL AMIDE; NEW DELHI METALLO BETA LACTAMASE 1 INHIBITOR; PHENYL AMIDE; THIOZOLE AMIDE; UNCLASSIFIED DRUG; HYDROLASE INHIBITOR; METALLO BETA LACTAMASE; NEW DELHI METALLO BETA LACTAMASE 1; PROPIONIC ACID DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; INTOXICATION; PHARMACOPHORE; BIOLOGICAL ACTIVITY; ENANTIOMER; HEAVY METAL POISONING; HYDROLYSIS; IC50;

BACTERIA (MICROORGANISMS);

3-MERCAPTO-2-METHYLPROPANOIC ACID; CAPTOPRIL; METALANTIDOTE; NDM-1 INHIBITOR;

BETA-LACTAMASES; CAPTOPRIL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84891490437     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.10.068     Document Type: Article

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