Rage mediates accelerated diabetic vein graft atherosclerosis induced by combined mechanical stress and ages via synergistic erk activation

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Li, Yuhuang ^a   Liu, Shuying ^a   Zhang, Zhengyu ^a   Xu, Qingbo ^b   Xie, Fukang ^a   Wang, Jingjing ^a   Ping, Suning ^a   Li, Chen ^a   Wang, Zhaojing ^a   Zhang, Min ^a   Huang, Jintao ^a   Chen, Dadi ^a   Hu, Liping ^a   Li, Chaohong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; GLUCOSE; KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ADVANCED GLYCOSYLATION END PRODUCT RECEPTOR; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; IMMUNOGLOBULIN RECEPTOR; MKI67 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE; CELL PROLIFERATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MECHANICAL STRESS; MOUSE; NEOINTIMA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER; STREPTOZOCIN DIABETES; VASCULAR SMOOTH MUSCLE; VEIN GRAFT; ANIMAL; C57BL MOUSE; DIABETIC ANGIOPATHY; EXPERIMENTAL DIABETES MELLITUS; GROWTH, DEVELOPMENT AND AGING; INTIMA; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSPLANTATION; VEIN;

MUS;

ANIMALS; ATHEROSCLEROSIS; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCOSYLATION END PRODUCTS, ADVANCED; KI-67 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, IMMUNOLOGIC; STRESS, MECHANICAL; TUNICA INTIMA; VEINS;

EID: 84859482152     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035016     Document Type: Article

References (44)

1. Cooper SA, Whaley-Connell A, Habibi J, Wei Y, Lastra G, et al. (2007) Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance. Am J Physiol Heart Circ Physiol 293: H2009-2023.
2. Nilsson PM, Cederholm J, (2011) Diabetes, hypertension, and outcome studies: overview 2010. Diabetes Care 34 (Suppl 2): S109-113.
3. Koka V, Wang W, Huang XR, Kim-Mitsuyama S, Truong LD, et al. (2006) Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications. Circulation 113: 1353-1360.
4. Cooper ME, (2001) Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy. Diabetologia 44: 1957-1972.
5. Salzberg SP, Filsoufi F, Anyanwu A, von Harbou K, Karlof E, et al. (2006) Increased neointimal formation after surgical vein grafting in a murine model of type 2 diabetes. Circulation 114: I302-307.
6. Brownlee M, (1995) Advanced protein glycosylation in diabetes and aging. Annu Rev Med 46: 223-234.
7. Vlassara H, Palace MR, (2002) Diabetes and advanced glycation endproducts. J Intern Med 251: 87-101.
8. Yamagishi S, (2011) Role of advanced glycation end products (AGEs) and receptor for AGEs (RAGE) in vascular damage in diabetes. Exp Gerontol 46: 217-224.
9. Li JH, Wang W, Huang XR, Oldfield M, Schmidt AM, et al. (2004) Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway. Am J Pathol 164: 1389-1397.
10. Soro-Paavonen A, Watson AM, Li J, Paavonen K, Koitka A, et al. (2008) Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes 57: 2461-2469.
11. Bu DX, Rai V, Shen X, Rosario R, Lu Y, et al. (2010) Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice. Circ Res 106: 1040-1051.
12. Rosen P, Nawroth PP, King G, Moller W, Tritschler HJ, et al. (2001) The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society. Diabetes Metab Res Rev 17: 189-212.
13. Schmidt AM, Yan SD, Wautier JL, Stern D, (1999) Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 84: 489-497.
14. Vlassara H, Fuh H, Donnelly T, Cybulsky M, (1995) Advanced glycation endproducts promote adhesion molecule (VCAM-1, ICAM-1) expression and atheroma formation in normal rabbits. Mol Med 1: 447-456.
15. Aronson D, (2003) Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes. J Hypertens 21: 3-12.
16. Bierhaus A, Nawroth PP, (2009) Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications. Diabetologia 52: 2251-2263.
17. Lombard JH, Eskinder H, Kauser K, Osborn JL, Harder DR, (1990) Enhanced norepinephrine sensitivity in renal arteries at elevated transmural pressure. Am J Physiol 259: H29-33.
18. Dobrin PB, (1995) Mechanical factors associated with the development of intimal and medial thickening in vein grafts subjected to arterial pressure. A model of arteries exposed to hypertension. Hypertension 26: 38-43.
19. Prado CM, Ramos SG, Alves-Filho JC, Elias J Jr, Cunha FQ, et al. (2006) Turbulent flow/low wall shear stress and stretch differentially affect aorta remodeling in rats. J Hypertens 24: 503-515.
20. Loop FD, Lytle BW, Cosgrove DM, Stewart RW, Goormastic M, et al. (1986) Influence of the internal-mammary-artery graft on 10-year survival and other cardiac events. N Engl J Med 314: 1-6.
21. Li C, Xu Q, (2000) Mechanical stress-initiated signal transductions in vascular smooth muscle cells. Cell Signal 12: 435-445.
22. Cheng Z, Hu L, Fu W, Zhang Q, Liao X, (2007) Expression of survivin and its splice variants in gastric cancer. J Huazhong Univ Sci Technolog Med Sci 27: 393-398.
23. Hu Y, Bock G, Wick G, Xu Q, (1998) Activation of PDGF receptor alpha in vascular smooth muscle cells by mechanical stress. FASEB J 12: 1135-1142.
24. Williams B, (1998) Mechanical influences on vascular smooth muscle cell function. J Hypertens 16: 1921-1929.
25. Zou Y, Dietrich H, Hu Y, Metzler B, Wick G, et al. (1998) Mouse model of venous bypass graft arteriosclerosis. Am J Pathol 153: 1301-1310.
26. Lewko B, Stepinski J, (2009) Hyperglycemia and mechanical stress: targeting the renal podocyte. J Cell Physiol 221: 288-295.
27. Zou Y, Akazawa H, Qin Y, Sano M, Takano H, et al. (2004) Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 6: 499-506.
28. Chien S, (2007) Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am J Physiol Heart Circ Physiol 292: H1209-1224.
29. Li C, Hu Y, Mayr M, Xu Q, (1999) Cyclic strain stress-induced mitogen-activated protein kinase (MAPK) phosphatase 1 expression in vascular smooth muscle cells is regulated by Ras/Rac-MAPK pathways. J Biol Chem 274: 25273-25280.
30. Zauli G, Toffoli B, di Iasio MG, Celeghini C, Fabris B, et al. (2010) Treatment with recombinant tumor necrosis factor-related apoptosis-inducing ligand alleviates the severity of streptozotocin-induced diabetes. Diabetes 59: 1261-1265.
31. Mayr U, Mayr M, Li C, Wernig F, Dietrich H, et al. (2002) Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice. Circ Res 90: 197-204.
32. Leitges M, Mayr M, Braun U, Mayr U, Li C, et al. (2001) Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice. J Clin Invest 108: 1505-1512.
33. Galler A, Muller G, Schinzel R, Kratzsch J, Kiess W, et al. (2003) Impact of metabolic control and serum lipids on the concentration of advanced glycation end products in the serum of children and adolescents with type 1 diabetes, as determined by fluorescence spectroscopy and nepsilon-(carboxymethyl)lysine ELISA. Diabetes Care 26: 2609-2615.
34. Kim JY, Park HK, Yoon JS, Kim SJ, Kim ES, et al. (2008) Advanced glycation end product (AGE)-induced proliferation of HEL cells via receptor for AGE-related signal pathways. Int J Oncol 33: 493-501.
35. Banes AJ, Gilbert J, Taylor D, Monbureau O, (1985) A new vacuum-operated stress-providing instrument that applies static or variable duration cyclic tension or compression to cells in vitro. J Cell Sci 75: 35-42.
36. Villacorta L, Zhang J, Garcia-Barrio MT, Chen XL, Freeman BA, et al. (2007) Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway. Am J Physiol Heart Circ Physiol 293: H770-776.
37. Hu Y, Zhang Z, Torsney E, Afzal AR, Davison F, et al. (2004) Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice. J Clin Invest 113: 1258-1265.
38. Hilker M, Tellmann G, Buerke M, Gloger K, Moersig W, et al. (2002) Proliferative activity in stenotic human aortocoronary bypass grafts. Cardiovasc Pathol 11: 284-290.
39. Park L, Raman KG, Lee KJ, Lu Y, Ferran LJ Jr, et al. (1998) Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 4: 1025-1031.
40. Bucciarelli LG, Wendt T, Qu W, Lu Y, Lalla E, et al. (2002) RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice. Circulation 106: 2827-2835.
41. Zhou Z, Wang K, Penn MS, Marso SP, Lauer MA, et al. (2003) Receptor for AGE (RAGE) mediates neointimal formation in response to arterial injury. Circulation 107: 2238-2243.
42. Sakaguchi T, Yan SF, Yan SD, Belov D, Rong LL, et al. (2003) Central role of RAGE-dependent neointimal expansion in arterial restenosis. J Clin Invest 111: 959-972.
43. Meloche J, Paulin R, Courboulin A, Lambert C, Barrier M, et al. (2011) RAGE-Dependent Activation of the Oncoprotein Pim1 Plays a Critical Role in Systemic Vascular Remodeling Processes. Arterioscler Thromb Vasc Biol 31: 2114-2124.
44. Shi Y, O'Brien JE, Fard A, Mannion JD, Wang D, et al. (1996) Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 94: 1655-1664.