메뉴 건너뛰기




Volumn 288, Issue 52, 2013, Pages 36971-36982

GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and breast cancer cell invasion

Author keywords

[No Author keywords available]

Indexed keywords

BASAL-LIKE BREAST CANCERS; BREAST CANCER; BREAST CANCER CELLS; OVER-EXPRESSION; SMAD SIGNALING;

EID: 84891467322     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.506535     Document Type: Article
Times cited : (50)

References (44)
  • 1
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
    • Siegel, P. M., and Massagué, J. (2003) Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer. Nat. Rev. Cancer 3, 807-821
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massagué, J.2
  • 2
    • 33746510500 scopus 로고    scopus 로고
    • Pro-metastasis function of TGFβ mediated by the Smad pathway
    • Kang, Y. (2006) Pro-metastasis function of TGFβ mediated by the Smad pathway. J. Cell Biochem. 98, 1380-1390
    • (2006) J. Cell Biochem. , vol.98 , pp. 1380-1390
    • Kang, Y.1
  • 3
    • 0034785348 scopus 로고    scopus 로고
    • TGF-β signaling in tumor suppression and cancer progression
    • Derynck, R., Akhurst, R. J., and Balmain, A. (2001) TGF-β signaling in tumor suppression and cancer progression. Nat. Genet. 29, 117-129
    • (2001) Nat. Genet. , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 4
    • 0842333147 scopus 로고    scopus 로고
    • Prognostic significance of transforming growth factor β receptor II in estrogen receptor-negative breast cancer patients
    • Buck, M. B., Fritz, P., Dippon, J., Zugmaier, G., and Knabbe, C. (2004) Prognostic significance of transforming growth factor β receptor II in estrogen receptor-negative breast cancer patients. Clin. Cancer Res. 10, 491-498
    • (2004) Clin. Cancer Res. , vol.10 , pp. 491-498
    • Buck, M.B.1    Fritz, P.2    Dippon, J.3    Zugmaier, G.4    Knabbe, C.5
  • 5
    • 41149157649 scopus 로고    scopus 로고
    • TGFβ primes breast tumors for lung metastasis seeding through angiopoietin-like 4
    • Padua, D., Zhang, X. H., Wang, Q., Nadal, C., Gerald, W. L., Gomis, R. R., and Massagué, J. (2008) TGFβ primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133, 66-77
    • (2008) Cell , vol.133 , pp. 66-77
    • Padua, D.1    Zhang, X.H.2    Wang, Q.3    Nadal, C.4    Gerald, W.L.5    Gomis, R.R.6    Massagué, J.7
  • 6
    • 73949087506 scopus 로고    scopus 로고
    • GATA3 in development and cancer differentiation. Cells GATA have it!
    • Chou, J., Provot, S., and Werb, Z. (2010) GATA3 in development and cancer differentiation. cells GATA have it! J. Cell Physiol. 222, 42-49
    • (2010) J. Cell Physiol. , vol.222 , pp. 42-49
    • Chou, J.1    Provot, S.2    Werb, Z.3
  • 8
    • 33751202983 scopus 로고    scopus 로고
    • GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland
    • Kouros-Mehr, H., Slorach, E. M., Sternlicht, M. D., and Werb, Z. (2006) GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell 127, 1041-1055
    • (2006) Cell , vol.127 , pp. 1041-1055
    • Kouros-Mehr, H.1    Slorach, E.M.2    Sternlicht, M.D.3    Werb, Z.4
  • 11
    • 29244481995 scopus 로고    scopus 로고
    • Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis
    • Mehra, R., Varambally, S., Ding, L., Shen, R., Sabel, M. S., Ghosh, D., Chinnaiyan, A. M., and Kleer, C. G. (2005) Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis. Cancer Res. 65, 11259-11264
    • (2005) Cancer Res. , vol.65 , pp. 11259-11264
    • Mehra, R.1    Varambally, S.2    Ding, L.3    Shen, R.4    Sabel, M.S.5    Ghosh, D.6    Chinnaiyan, A.M.7    Kleer, C.G.8
  • 12
    • 77951546955 scopus 로고    scopus 로고
    • GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition
    • Yan, W., Cao, Q. J., Arenas, R. B., Bentley, B., and Shao, R. (2010) GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition. J. Biol. Chem. 285, 14042-14051
    • (2010) J. Biol. Chem. , vol.285 , pp. 14042-14051
    • Yan, W.1    Cao, Q.J.2    Arenas, R.B.3    Bentley, B.4    Shao, R.5
  • 13
    • 84873364088 scopus 로고    scopus 로고
    • GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression
    • Chou, J., Lin, J. H., Brenot, A., Kim, J. W., Provot, S., and Werb, Z. (2013) GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat. Cell Biol. 15, 201-213
    • (2013) Nat. Cell Biol. , vol.15 , pp. 201-213
    • Chou, J.1    Lin, J.H.2    Brenot, A.3    Kim, J.W.4    Provot, S.5    Werb, Z.6
  • 16
    • 84875969667 scopus 로고    scopus 로고
    • Expression of GATA3 in MDA-MB-231 triplenegative breast cancer cells induces a growth inhibitory response to TGFß
    • Chu, I. M., Lai, W. C., Aprelikova, O., El Touny, L. H., Kouros-Mehr, H., and Green, J. E. (2013) Expression of GATA3 in MDA-MB-231 triplenegative breast cancer cells induces a growth inhibitory response to TGFß. PLoS ONE 8, e61125
    • (2013) PLoS ONE , vol.8
    • Chu, I.M.1    Lai, W.C.2    Aprelikova, O.3    El Touny, L.H.4    Kouros-Mehr, H.5    Green, J.E.6
  • 17
    • 77951116071 scopus 로고    scopus 로고
    • Migrastatin analogues target fascin to block tumour metastasis
    • Chen, L., Yang, S., Jakoncic, J., Zhang, J. J., and Huang, X. Y. (2010) Migrastatin analogues target fascin to block tumour metastasis. Nature 464, 1062-1066
    • (2010) Nature , vol.464 , pp. 1062-1066
    • Chen, L.1    Yang, S.2    Jakoncic, J.3    Zhang, J.J.4    Huang, X.Y.5
  • 19
    • 80655125031 scopus 로고    scopus 로고
    • Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells
    • Sun, J., He, H., Xiong, Y., Lu, S., Shen, J., Cheng, A., Chang, W. C., Hou, M. F., Lancaster, J. M., Kim, M., and Yang, S. (2011) Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells. J. Biol. Chem. 286, 38865-38875
    • (2011) J. Biol. Chem. , vol.286 , pp. 38865-38875
    • Sun, J.1    He, H.2    Xiong, Y.3    Lu, S.4    Shen, J.5    Cheng, A.6    Chang, W.C.7    Hou, M.F.8    Lancaster, J.M.9    Kim, M.10    Yang, S.11
  • 20
  • 21
    • 79956208360 scopus 로고    scopus 로고
    • Fascin. Invasive filopodia promoting metastasis
    • Machesky, L. M., and Li, A. (2010) Fascin. Invasive filopodia promoting metastasis. Commun. Integr. Biol. 3, 263-270
    • (2010) Commun. Integr. Biol. , vol.3 , pp. 263-270
    • MacHesky, L.M.1    Li, A.2
  • 23
  • 24
    • 77956765017 scopus 로고    scopus 로고
    • Specificity protein 1 regulates fascin expression in esophageal squamous cell carcinoma as the result of the epidermal growth factor/extracellular signal-regulated kinase signaling pathway activation
    • Lu, X. F., Li, E. M., Du, Z. P., Xie, J. J., Guo, Z. Y., Gao, S. Y., Liao, L. D., Shen, Z. Y., Xie, D., and Xu, L. Y. (2010) Specificity protein 1 regulates fascin expression in esophageal squamous cell carcinoma as the result of the epidermal growth factor/extracellular signal-regulated kinase signaling pathway activation. Cell. Mol. Life Sci. 67, 3313-3329
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 3313-3329
    • Lu, X.F.1    Li, E.M.2    Du, Z.P.3    Xie, J.J.4    Guo, Z.Y.5    Gao, S.Y.6    Liao, L.D.7    Shen, Z.Y.8    Xie, D.9    Xu, L.Y.10
  • 25
    • 67650731588 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation assays. Analyzing transcription factor binding and histone modifications in vivo
    • Pillai, S., Dasgupta, P., and Chellappan, S. P. (2009) Chromatin immunoprecipitation assays. Analyzing transcription factor binding and histone modifications in vivo. Methods Mol. Biol. 523, 323-339
    • (2009) Methods Mol. Biol. , vol.523 , pp. 323-339
    • Pillai, S.1    Dasgupta, P.2    Chellappan, S.P.3
  • 26
    • 33645507413 scopus 로고    scopus 로고
    • Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia. Defining the stages of invadopodia formation and function
    • Artym, V. V., Zhang, Y., Seillier-Moiseiwitsch, F., Yamada, K. M., and Mueller, S. C. (2006) Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia. Defining the stages of invadopodia formation and function. Cancer Res. 66, 3034-3043
    • (2006) Cancer Res. , vol.66 , pp. 3034-3043
    • Artym, V.V.1    Zhang, Y.2    Seillier-Moiseiwitsch, F.3    Yamada, K.M.4    Mueller, S.C.5
  • 27
    • 22844433788 scopus 로고    scopus 로고
    • 2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration
    • 2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration. J. Biol. Chem. 280, 27130-27137
    • (2005) J. Biol. Chem. , vol.280 , pp. 27130-27137
    • Yang, S.1    Huang, X.Y.2
  • 28
    • 33744520458 scopus 로고    scopus 로고
    • Role of tyrosine kinase Csk in G protein-coupled receptor- and receptor tyrosine kinaseinduced fibroblast cell migration
    • McGarrigle, D., Shan, D., Yang, S., and Huang, X. Y. (2006) Role of tyrosine kinase Csk in G protein-coupled receptor- and receptor tyrosine kinaseinduced fibroblast cell migration. J. Biol. Chem. 281, 10583-10588
    • (2006) J. Biol. Chem. , vol.281 , pp. 10583-10588
    • McGarrigle, D.1    Shan, D.2    Yang, S.3    Huang, X.Y.4
  • 29
    • 0042591370 scopus 로고    scopus 로고
    • The human fascin gene promoter is highly active in mature dendritic cells due to a stage-specific enhancer
    • Bros, M., Ross, X. L., Pautz, A., Reske-Kunz, A. B., and Ross, R. (2003) The human fascin gene promoter is highly active in mature dendritic cells due to a stage-specific enhancer. J. Immunol. 171, 1825-1834
    • (2003) J. Immunol. , vol.171 , pp. 1825-1834
    • Bros, M.1    Ross, X.L.2    Pautz, A.3    Reske-Kunz, A.B.4    Ross, R.5
  • 33
    • 79959541003 scopus 로고    scopus 로고
    • The "ins" and "outs" of podosomes and invadopodia. Characteristics, formation. And function
    • Murphy, D. A., and Courtneidge, S. A. (2011) The "ins" and "outs" of podosomes and invadopodia. Characteristics, formation. and function. Nat. Rev. Mol. Cell Biol. 12, 413-426
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 413-426
    • Murphy, D.A.1    Courtneidge, S.A.2
  • 34
    • 77951771838 scopus 로고    scopus 로고
    • Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
    • Schoumacher, M., Goldman, R. D., Louvard, D., and Vignjevic, D. M. (2010) Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J. Cell Biol. 189, 541-556
    • (2010) J. Cell Biol. , vol.189 , pp. 541-556
    • Schoumacher, M.1    Goldman, R.D.2    Louvard, D.3    Vignjevic, D.M.4
  • 35
    • 21844439742 scopus 로고    scopus 로고
    • Roles of fascin in human carcinoma motility and signaling. Prospects for a novel biomarker?
    • Hashimoto, Y., Skacel, M., and Adams, J. C. (2005) Roles of fascin in human carcinoma motility and signaling. Prospects for a novel biomarker? Int. J. Biochem. Cell Biol. 37, 1787-1804
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 1787-1804
    • Hashimoto, Y.1    Skacel, M.2    Adams, J.C.3
  • 36
    • 11344285907 scopus 로고    scopus 로고
    • The expression of fascin, an actinbundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course
    • Yoder, B. J., Tso, E., Skacel, M., Pettay, J., Tarr, S., Budd, T., Tubbs, R. R., Adams, J. C., and Hicks, D. G. (2005) The expression of fascin, an actinbundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course. Clin. Cancer Res. 11, 186-192
    • (2005) Clin. Cancer Res. , vol.11 , pp. 186-192
    • Yoder, B.J.1    Tso, E.2    Skacel, M.3    Pettay, J.4    Tarr, S.5    Budd, T.6    Tubbs, R.R.7    Adams, J.C.8    Hicks, D.G.9
  • 37
    • 80655144746 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration
    • Snyder, M., Huang, X. Y., and Zhang, J. J. (2011) Signal transducers and activators of transcription 3 (STAT3) directly regulates cytokine-induced fascin expression and is required for breast cancer cell migration. J. Biol. Chem. 286, 38886-38893
    • (2011) J. Biol. Chem. , vol.286 , pp. 38886-38893
    • Snyder, M.1    Huang, X.Y.2    Zhang, J.J.3
  • 38
    • 68949111887 scopus 로고    scopus 로고
    • TGF-β promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways
    • Fu, H., Hu, Z., Wen, J., Wang, K., and Liu, Y. (2009) TGF-β promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways. Acta Biochim. Biophys. Sin. 41, 648-656
    • (2009) Acta Biochim. Biophys. Sin. , vol.41 , pp. 648-656
    • Fu, H.1    Hu, Z.2    Wen, J.3    Wang, K.4    Liu, Y.5
  • 39
    • 60849087975 scopus 로고    scopus 로고
    • Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and correspondingmRNAexpression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-β-Induced epithelial-mesenchymal transition
    • Keshamouni, V. G., Jagtap, P., Michailidis, G., Strahler, J. R., Kuick, R., Reka, A. K., Papoulias, P., Krishnapuram, R., Srirangam, A., Standiford, T. J., Andrews, P. C., and Omenn, G. S. (2009) Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and correspondingmRNAexpression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-β-Induced epithelial-mesenchymal transition. J. Proteome Res. 8, 35-47
    • (2009) J. Proteome Res. , vol.8 , pp. 35-47
    • Keshamouni, V.G.1    Jagtap, P.2    Michailidis, G.3    Strahler, J.R.4    Kuick, R.5    Reka, A.K.6    Papoulias, P.7    Krishnapuram, R.8    Srirangam, A.9    Standiford, T.J.10    Andrews, P.C.11    Omenn, G.S.12
  • 40
    • 79953699628 scopus 로고    scopus 로고
    • The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-κB signals
    • Kress, A. K., Kalmer, M., Rowan, A. G., Grassmann, R., and Fleckenstein, B. (2011) The tumor marker Fascin is strongly induced by the Tax oncoprotein of HTLV-1 through NF-κB signals. Blood 117, 3609-3612
    • (2011) Blood , vol.117 , pp. 3609-3612
    • Kress, A.K.1    Kalmer, M.2    Rowan, A.G.3    Grassmann, R.4    Fleckenstein, B.5
  • 42
    • 0037039160 scopus 로고    scopus 로고
    • Physical and functional interaction between GATA-3 and Smad3 allows TGF-β regulation of GATA target genes
    • Blokzijl, A., ten Dijke, P., and Ibáñez, C. F. (2002) Physical and functional interaction between GATA-3 and Smad3 allows TGF-β regulation of GATA target genes. Curr. Biol. 12, 35-45
    • (2002) Curr. Biol. , vol.12 , pp. 35-45
    • Blokzijl, A.1    Ten Dijke, P.2    Ibáñez, C.F.3
  • 44
    • 58149236744 scopus 로고    scopus 로고
    • Roles of TGFβ in metastasis
    • Padua, D., and Massagué, J. (2009) Roles of TGFβ in metastasis. Cell Res 19, 89-102
    • (2009) Cell Res , vol.19 , pp. 89-102
    • Padua, D.1    Massagué, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.