Fascin protein is critical for transforming growth factor β protein-induced invasion and filopodia formation in spindle-shaped tumor cells

Journal of Biological Chemistry

Volumn 286, Issue 45, 2011, Pages 38865-38875

  Sun, Jianwei ^a   He, Huifang ^a   Xiong, Yin ^a   Lu, Shuang ^a   Shen, Junling ^a,b   Cheng, Anna ^a   Chang, Wei Chiao ^c   Hou, Ming Feng ^c   Lancaster, Johnathan M ^a   Kim, Minjung ^a   Yang, Shengyu ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b QINGDAO AGRICULTURAL UNIVERSITY   (China)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST TUMOR; CYTOKINES; LATE STAGE; MESENCHYMAL CELLS; METASTATIC DISEASE; METASTATIC TUMORS; OVER-EXPRESSION; TRANSFORMING GROWTH FACTORS; TUMOR CELLS; TUMOR METASTASIS; TUMOR MICROENVIRONMENT;

ENZYME INHIBITION; PATHOLOGY; PROTEINS;

TUMORS;

FASCIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ACTIN FILAMENT; ARTICLE; BREAST TUMOR; CELL INVASION; CELL MIGRATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; FILOPODIUM; HUMAN; HUMAN TISSUE; LAMELLIPODIUM; MEMBRANE BIOLOGY; MEMBRANE PROTRUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SPINDLE CELL; TUMOR CELL; TUMOR MICROENVIRONMENT;

BREAST NEOPLASMS; CARRIER PROTEINS; CELL LINE, TUMOR; CELL SHAPE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICROFILAMENT PROTEINS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PSEUDOPODIA; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 80655125031     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.270413     Document Type: Article

References (42)

1. Mareel, M., and Leroy, A. (2003) Physiol. Rev. 83, 337-376
2. Webb, D. J., Parsons, J. T., and Horwitz, A. F. (2002) Nat. Cell Biol. 4, E97-100
3. Mogilner, A., and Rubinstein, B. (2005) Biophys. J. 89, 782-795
4. Hashimoto, Y., Skacel, M., and Adams, J. C. (2005) Int. J. Biochem. Cell Biol. 37, 1787-1804
5. Vignjevic, D., Schoumacher, M., Gavert, N., Janssen, K. P., Jih, G., Laé, M., Louvard, D., Ben-Ze'ev, A., and Robine, S. (2007) Cancer Res. 67, 6844-6853
6. Chen, L., Yang, S., Jakoncic, J., Zhang, J. J., and Huang, X. Y. (2010) Nature 464, 1062-1066
7. Pelosi, G., Pasini, F., Fraggetta, F., Pastorino, U., Iannucci, A., Maisonneuve, P., Arrigoni, G., De Manzoni, G., Bresaola, E., and Viale, G. (2003) Lung Cancer 42, 203-213
8. Hashimoto, Y., Skacel, M., Lavery, I. C., Mukherjee, A. L., Casey, G., and Adams, J. C. (2006) BMC Cancer 6, 241
9. Hashimoto, Y., Shimada, Y., Kawamura, J., Yamasaki, S., and Imamura, M. (2004) Oncology 67, 262-270
10. Hashimoto, Y., Ito, T., Inoue, H., Okumura, T., Tanaka, E., Tsunoda, S., Higashiyama, M., Watanabe, G., Imamura, M., and Shimada, Y. (2005) Clin. Cancer Res. 11, 2597-2605
11. Yoder, B. J., Tso, E., Skacel, M., Pettay, J., Tarr, S., Budd, T., Tubbs, R. R., Adams, J. C., and Hicks, D. G. (2005) Clin. Cancer Res. 11, 186-192
12. Puppa, G., Maisonneuve, P., Sonzogni, A., Masullo, M., Chiappa, A., Valerio, M., Zampino, M. G., Franceschetti, I., Capelli, P., Chilosi, M., Menestrina, F., Viale, G., and Pelosi, G. (2007) Br. J. Cancer 96, 1118-1126
13. Hashimoto, Y., Parsons, M., and Adams, J. C. (2007) Mol. Biol. Cell 18, 4591-4602
14. Padua, D., Zhang, X. H., Wang, Q., Nadal, C., Gerald, W. L., Gomis, R. R., and Massagué, J. (2008) Cell 133, 66-77
15. Kang, Y. (2006) J. Cell Biochem. 98, 1380-1390
16. Stoler, A. B., Stenback, F., and Balmain, A. (1993) J. Cell Biol. 122, 1103-1117
17. Derynck, R., Akhurst, R. J., and Balmain, A. (2001) Nat. Genet. 29, 117-129
18. Neve, R. M., Chin, K., Fridlyand, J., Yeh, J., Baehner, F. L., Fevr, T., Clark, L., Bayani, N., Coppe, J. P., Tong, F., Speed, T., Spellman, P. T., DeVries, S., Lapuk, A., Wang, N. J., Kuo, W. L., Stilwell, J. L., Pinkel, D., Albertson, D. G., Waldman, F. M., McCormick, F., Dickson, R. B., Johnson, M. D., Lippman, M., Ethier, S., Gazdar, A., and Gray, J. W. (2006) Cancer Cell 10, 515-527
19. Goncharuk, V. N., Ross, J. S., and Carlson, J. A. (2002) J. Cutan Pathol. 29, 430-438
20. He, W., Dorn, D. C., Erdjument-Bromage, H., Tempst, P., Moore, M. A., and Massagué, J. (2006) Cell 125, 929-941
21. Yang, S., and Huang, X. Y. (2005) J. Biol. Chem. 280, 27130-27137
22. Yang, S., Zhang, J. J., and Huang, X. Y. (2009) Cancer Cell 15, 124-134
23. Ridley, A. J., Schwartz, M. A., Burridge, K., Firtel, R. A., Ginsberg, M. H., Borisy, G., Parsons, J. T., and Horwitz, A. R. (2003) Science 302, 1704-1709
24. Moustakas, A., and Stournaras, C. (1999) J. Cell Sci. 112, 1169-1179
25. Bakin, A. V., Safina, A., Rinehart, C., Daroqui, C., Darbary, H., and Helfman, D. M. (2004) Mol. Biol. Cell 15, 4682-4694
26. Machesky, L. M., and Li, A. (2010) Commun. Integr. Biol. 3, 263-270
27. Vignjevic, D., Kojima, S., Aratyn, Y., Danciu, O., Svitkina, T., and Borisy, G. G. (2006) J. Cell Biol. 174, 863-875
28. Derynck, R., and Zhang, Y. E. (2003) Nature 425, 577-584
29. Hashimoto, Y., Loftis, D. W., and Adams, J. C. (2009) PLoS One 4, e5130
30. Bros, M., Ross, X. L., Pautz, A., Reske-Kunz, A. B., and Ross, R. (2003) J. Immunol. 171, 1825-1834
31. Feng, X. H., Lin, X., and Derynck, R. (2000) EMBO J. 19, 5178-5193
32. Romano, L. A., and Runyan, R. B. (2000) Dev. Biol. 223, 91-102
33. Liu, X., Sun, Y., Weinberg, R. A., and Lodish, H. F. (2001) Cytokine Growth Factor Rev. 12, 1-8
34. Minn, A. J., Gupta, G. P., Siegel, P. M., Bos, P. D., Shu, W., Giri, D. D., Viale, A., Olshen, A. B., Gerald, W. L., and Massagué, J. (2005) Nature 436, 518-524
35. Grothey, A., Hashizume, R., Ji, H., Tubb, B. E., Patrick, C. W., Jr., Yu, D., Mooney, E. E., and McCrea, P. D. (2000) Oncogene 19, 4864-4875
36. Adorno, M., Cordenonsi, M., Montagner, M., Dupont, S., Wong, C., Hann, B., Solari, A., Bobisse, S., Rondina, M. B., Guzzardo, V., Parenti, A. R., Rosato, A., Bicciato, S., Balmain, A., and Piccolo, S. (2009) Cell 137, 87-98
37. Massagué, J., and Chen, Y. G. (2000) Genes Dev. 14, 627-644
38. Buck, M. B., Fritz, P., Dippon, J., Zugmaier, G., and Knabbe, C. (2004) Clin. Cancer Res. 10, 491-498
39. Hagedorn, H. G., Bachmeier, B. E., and Nerlich, A. G. (2001) Int. J. Oncol. 18, 669-681
40. Yamaguchi, H., Lorenz, M., Kempiak, S., Sarmiento, C., Coniglio, S., Symons, M., Segall, J., Eddy, R., Miki, H., Takenawa, T., and Condeelis, J. (2005) J. Cell Biol. 168, 441-452
41. Schoumacher, M., Goldman, R. D., Louvard, D., and Vignjevic, D. M. (2010) J. Cell Biol. 189, 541-556
42. Li, A., Dawson, J. C., Forero-Vargas, M., Spence, H. J., Yu, X., König, I., Anderson, K., and Machesky, L. M. (2010) Curr. Biol. 20, 339-345