Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells

Cellular Signalling

Volumn 26, Issue 3, 2014, Pages 603-610

  Matsuhashi, Sachiko ^a   Hamajima, Hiroshi ^a   Xia, JingHe ^a   Zhang, Hao ^b   Mizuta, Toshihiko ^a   Anzai, Keizo ^a   Ozaki, Iwata ^a  

^a SAGA UNIVERSITY   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; EGF; Huh7 hepatoma cells; PDCD4; TGF 1; TPA

Indexed keywords

ALANINE; EPIDERMAL GROWTH FACTOR; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOGENIC AGENT; PEPTIDES AND PROTEINS; PHOSPHATIDYLINOSITOL 3 KINASE; PROGRAMMED CELL DEATH 4; PROTEASOME; PROTEIN BETA TRCP; PROTEIN KINASE B; S6 KINASE; S6 KINASE 1; SERINE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; CANCER CELL; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MUTANT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

APOPTOSIS; EGF; HUH7 HEPATOMA CELLS; PDCD4; TGF-Β1; TPA;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; EPIDERMAL GROWTH FACTOR; HUMANS; LIVER NEOPLASMS; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS; SMAD PROTEINS; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84891444142     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2013.11.038     Document Type: Article

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