-
1
-
-
78549245806
-
Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
-
Yukl, S.A.; Shergill, A.; McQuaid, K.; Gianella, S.; Lampiris, H.; Hare, C.B.; Pandori, M.; Sinclair, E.; Günthard, H.F.; Fischer, M., et al. Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS 2010, 24, 2451-2460.
-
(2010)
AIDS
, vol.24
, pp. 2451-2460
-
-
Yukl, S.A.1
Shergill, A.2
McQuaid, K.3
Gianella, S.4
Lampiris, H.5
Hare, C.B.6
Pandori, M.7
Sinclair, E.8
Günthard, H.F.9
Fischer, M.10
-
2
-
-
79551614790
-
HIV infection, inflammation, immunosenescence, and aging
-
Deeks, S.G. HIV infection, inflammation, immunosenescence, and aging. Medicine 2011, 62, 141-155.
-
(2011)
Medicine
, vol.62
, pp. 141-155
-
-
Deeks, S.G.1
-
3
-
-
77954734865
-
Antiretroviral therapy and management of HIV infection
-
Volberding, P.A.; Deeks, S.G. Antiretroviral therapy and management of HIV infection. Lancet 2010, 376, 49-62.
-
(2010)
Lancet
, vol.376
, pp. 49-62
-
-
Volberding, P.A.1
Deeks, S.G.2
-
4
-
-
0028041714
-
Progress towards gene therapy for HIV infection
-
Yu, M.; Poeschla, E.; Wong-Staal, F. Progress towards gene therapy for HIV infection. Gene Ther. 1994, 1, 13-26.
-
(1994)
Gene Ther
, vol.1
, pp. 13-26
-
-
Yu, M.1
Poeschla, E.2
Wong-Staal, F.3
-
5
-
-
0032843345
-
Gene therapy for HIV infections: Intracellular immunization
-
Piché, A. Gene therapy for HIV infections: Intracellular immunization. Can. J. Infect. Dis. 1999, 10, 307-312.
-
(1999)
Can. J. Infect. Dis
, vol.10
, pp. 307-312
-
-
Piché, A.1
-
6
-
-
84877976331
-
Thirty years on: HIV receptor gymnastics and the prevention of infection
-
Weiss, R.A. Thirty years on: HIV receptor gymnastics and the prevention of infection. BMC Biol. 2013, 11, e57.
-
(2013)
BMC Biol
, vol.11
-
-
Weiss, R.A.1
-
7
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu, R.; Paxton, W.A.; Choe, S.; Ceradini, D.; Martin, S.R.; Horuk, R.; MacDonald, M.E.; Stuhlmann, H.; Koup, R.A.; Landau, N.R. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996, 86, 367-377.
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
Ceradini, D.4
Martin, S.R.5
Horuk, R.6
Macdonald, M.E.7
Stuhlmann, H.8
Koup, R.A.9
Landau, N.R.10
-
8
-
-
0007643930
-
Association between CCR5 genotype and the clinical course of HIV-1 infection
-
De Roda Husman, A.M.; Koot, M.; Cornelissen, M.; Keet, I.P.; Brouwer, M.; Broersen, S.M.; Bakker, M.; Roos, M.T.; Prins, M.; de Wolf, F.; et al. Association between CCR5 genotype and the clinical course of HIV-1 infection. Ann. Intern. Med. 1997, 127, 882-890.
-
(1997)
Ann. Intern. Med
, vol.127
, pp. 882-890
-
-
De Roda Husman, A.M.1
Koot, M.2
Cornelissen, M.3
Keet, I.P.4
Brouwer, M.5
Broersen, S.M.6
Bakker, M.7
Roos, M.T.8
Prins, M.9
de Wolf, F.10
-
10
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
Hütter, G.; Nowak, D.; Mossner, M.; Ganepola, S.; Müßig, A.; Allers, K.; Schneider, T.; Hofmann, J.; Kücherer, C.; Blau, O. et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N. Engl. J. Med. 2009, 360, 692-698.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 692-698
-
-
Hütter, G.1
Nowak, D.2
Mossner, M.3
Ganepola, S.4
Müßig, A.5
Allers, K.6
Schneider, T.7
Hofmann, J.8
Kücherer, C.9
Blau, O.10
-
11
-
-
79953117041
-
Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation
-
Allers, K.; Hütter, G.; Hofmann, J.; Loddenkemper, C.; Rieger, K.; Thiel, E.; Schneider, T. Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation. Blood 2011, 117, 2791-2799.
-
(2011)
Blood
, vol.117
, pp. 2791-2799
-
-
Allers, K.1
Hütter, G.2
Hofmann, J.3
Loddenkemper, C.4
Rieger, K.5
Thiel, E.6
Schneider, T.7
-
12
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin, X.-F.; An, D.S.; Chen, I.S.Y.; Baltimore, D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA 2003, 100, 183-188.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 183-188
-
-
Qin, X.-F.1
An, D.S.2
Chen, I.S.Y.3
Baltimore, D.4
-
13
-
-
0034149743
-
Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo
-
Bai, J.; Gorantla, S.; Banda, N.; Cagnon, L.; Rossi, J.; Akkina, R. Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo. Mol. Ther. 2000, 1, 244-254.
-
(2000)
Mol. Ther
, vol.1
, pp. 244-254
-
-
Bai, J.1
Gorantla, S.2
Banda, N.3
Cagnon, L.4
Rossi, J.5
Akkina, R.6
-
14
-
-
33745941234
-
T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery
-
Swan, C.H.; Bühler, B.; Steinberger, P.; Tschan, M.P.; Barbas, C.F.; Torbett, B.E. T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery. Gene Ther. 2006, 13, 1480-1492.
-
(2006)
Gene Ther
, vol.13
, pp. 1480-1492
-
-
Swan, C.H.1
Bühler, B.2
Steinberger, P.3
Tschan, M.P.4
Barbas, C.F.5
Torbett, B.E.6
-
15
-
-
0036290645
-
Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection
-
Schroers, R.; Davis, C.M.; Wagner, H.-J.; Chen, S.-Y. Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection. Gene Ther. 2002, 9, 889-897.
-
(2002)
Gene Ther
, vol.9
, pp. 889-897
-
-
Schroers, R.1
Davis, C.M.2
Wagner, H.-J.3
Chen, S.-Y.4
-
16
-
-
77949885010
-
A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
-
Shimizu, S.; Hong, P.; Arumugam, B.; Pokomo, L.; Boyer, J.; Koizumi, N.; Kittipongdaja, P.; Chen, A.; Bristol, G.; Galic, Z. et al. A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model. Blood 2010, 115, 1534-1544.
-
(2010)
Blood
, vol.115
, pp. 1534-1544
-
-
Shimizu, S.1
Hong, P.2
Arumugam, B.3
Pokomo, L.4
Boyer, J.5
Koizumi, N.6
Kittipongdaja, P.7
Chen, A.8
Bristol, G.9
Galic, Z.10
-
17
-
-
79952697048
-
Targeted genome editing in pluripotent stem cells using zinc-finger nucleases
-
Bobis-Wozowicz, S.; Osiak, A.; Rahman, S.H.; Cathomen, T. Targeted genome editing in pluripotent stem cells using zinc-finger nucleases. Methods 2011, 53, 339-346.
-
(2011)
Methods
, vol.53
, pp. 339-346
-
-
Bobis-Wozowicz, S.1
Osiak, A.2
Rahman, S.H.3
Cathomen, T.4
-
18
-
-
46949095221
-
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
-
Perez, E.E.; Wang, J.; Miller, J.C.; Jouvenot, Y.; Kim, K.A.; Liu, O.; Wang, N.; Lee, G.; Bartsevich, V.V.; Lee, Y.-L. et al. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat. Biotechnol. 2008, 26, 808-816.
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 808-816
-
-
Perez, E.E.1
Wang, J.2
Miller, J.C.3
Jouvenot, Y.4
Kim, K.A.5
Liu, O.6
Wang, N.7
Lee, G.8
Bartsevich, V.V.9
Lee, Y.-L.10
-
19
-
-
78650735673
-
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
-
Holt, N.; Wang, J.; Kim, K.; Friedman, G.; Wang, X.; Taupin, V.; Crooks, G.M.; Kohn, D.B.; Gregory, P.D.; Holmes, M.C. et al. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo. Nat. Biotechnol. 2010, 28, 839-847.
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 839-847
-
-
Holt, N.1
Wang, J.2
Kim, K.3
Friedman, G.4
Wang, X.5
Taupin, V.6
Crooks, G.M.7
Kohn, D.B.8
Gregory, P.D.9
Holmes, M.C.10
-
20
-
-
84878528467
-
Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases
-
Li, L.; Krymskaya, L.; Wang, J.; Henley, J.; Rao, A.; Cao, L.-F.; Tran, C.-A.; Torres-Coronado, M.; Gardner, A.; Gonzalez, N. et al. Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases. Mol. Ther. 2013, 21, 1259-1269.
-
(2013)
Mol. Ther
, vol.21
, pp. 1259-1269
-
-
Li, L.1
Krymskaya, L.2
Wang, J.3
Henley, J.4
Rao, A.5
Cao, L.-F.6
Tran, C.-A.7
Torres-Coronado, M.8
Gardner, A.9
Gonzalez, N.10
-
21
-
-
79955785236
-
Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases
-
Wilen, C.B.; Wang, J.; Tilton, J.C.; Miller, J.C.; Kim, K.A.; Rebar, E.J.; Sherrill-Mix, S.A.; Patro, S.C.; Secreto, A.J.; Jordan, A.P.O.; et al. Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases. PLoS Pathog. 2011, 7, e1002020.
-
(2011)
PLoS Pathog
, vol.7
-
-
Wilen, C.B.1
Wang, J.2
Tilton, J.C.3
Miller, J.C.4
Kim, K.A.5
Rebar, E.J.6
Sherrill-Mix, S.A.7
Patro, S.C.8
Secreto, A.J.9
Jordan, A.P.O.10
-
22
-
-
84856753063
-
Hematopoietic-stem-cell-based gene therapy for HIV disease
-
Kiem, H.-P.; Jerome, K.R.; Deeks, S.G.; McCune, J.M. Hematopoietic-stem-cell-based gene therapy for HIV disease. Stem Cell 2012, 10, 137-147.
-
(2012)
Stem Cell
, vol.10
, pp. 137-147
-
-
Kiem, H.-P.1
Jerome, K.R.2
Deeks, S.G.3
McCune, J.M.4
-
23
-
-
62049083710
-
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells
-
Mitsuyasu, R.T.; Merigan, T.C.; Carr, A.; Zack, J.A.; Winters, M.A.; Workman, C.; Bloch, M.; Lalezari, J.; Becker, S.; Thornton, L. et al. Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells. Nat. Med. 2009, 15, 285-292.
-
(2009)
Nat. Med
, vol.15
, pp. 285-292
-
-
Mitsuyasu, R.T.1
Merigan, T.C.2
Carr, A.3
Zack, J.A.4
Winters, M.A.5
Workman, C.6
Bloch, M.7
Lalezari, J.8
Becker, S.9
Thornton, L.10
-
24
-
-
0037079706
-
Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome
-
Kang, E.M.; de Witte, M.; Malech, H.; Morgan, R.A.; Phang, S.; Carter, C.; Leitman, S.F.; Childs, R.; Barrett, A.J.; Little, R. et al. Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome. Blood 2002, 99, 698-701.
-
(2002)
Blood
, vol.99
, pp. 698-701
-
-
Kang, E.M.1
de Witte, M.2
Malech, H.3
Morgan, R.A.4
Phang, S.5
Carter, C.6
Leitman, S.F.7
Childs, R.8
Barrett, A.J.9
Little, R.10
-
25
-
-
0030919846
-
RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication
-
Bonyhadi, M.L.; Moss, K.; Voytovich, A.; Auten, J.; Kalfoglou, C.; Plavec, I.; Forestell, S.; Su, L.; Böhnlein, E.; Kaneshima, H. RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication. J. Virol. 1997, 71, 4707-4716.
-
(1997)
J. Virol
, vol.71
, pp. 4707-4716
-
-
Bonyhadi, M.L.1
Moss, K.2
Voytovich, A.3
Auten, J.4
Kalfoglou, C.5
Plavec, I.6
Forestell, S.7
Su, L.8
Böhnlein, E.9
Kaneshima, H.10
-
26
-
-
20844440241
-
Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34+ cells
-
Podsakoff, G.M.; Engel, B.C.; Carbonaro, D.A.; Choi, C.; Smogorzewska, E.M.; Bauer, G.; Selander, D.; Csik, S.; Wilson, K.; Betts, M.R. et al. Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34+ cells. Mol. Ther. 2005, 12, 77-86.
-
(2005)
Mol. Ther
, vol.12
, pp. 77-86
-
-
Podsakoff, G.M.1
Engel, B.C.2
Carbonaro, D.A.3
Choi, C.4
Smogorzewska, E.M.5
Bauer, G.6
Selander, D.7
Csik, S.8
Wilson, K.9
Betts, M.R.10
-
27
-
-
0033168686
-
A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children
-
Kohn, D.B.; Bauer, G.; Rice, C.R.; Rothschild, J.C.; Carbonaro, D.A.; Valdez, P.; Hao, Q.L.; Zhou, C.; Bahner, I.; Kearns, K. et al. A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children. Blood 1999, 94, 368-371.
-
(1999)
Blood
, vol.94
, pp. 368-371
-
-
Kohn, D.B.1
Bauer, G.2
Rice, C.R.3
Rothschild, J.C.4
Carbonaro, D.A.5
Valdez, P.6
Hao, Q.L.7
Zhou, C.8
Bahner, I.9
Kearns, K.10
-
28
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque, J.-M.; Triques, K.; Stevenson, M. Modulation of HIV-1 replication by RNA interference. Nature 2002, 418, 435-438.
-
(2002)
Nature
, vol.418
, pp. 435-438
-
-
Jacque, J.-M.1
Triques, K.2
Stevenson, M.3
-
29
-
-
1242319384
-
Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition
-
Das, A.T.; Brummelkamp, T.R.; Westerhout, E.M.; Vink, M.; Madiredjo, M.; Bernards, R.; Berkhout, B. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 2004, 78, 2601-2605.
-
(2004)
J. Virol
, vol.78
, pp. 2601-2605
-
-
Das, A.T.1
Brummelkamp, T.R.2
Westerhout, E.M.3
Vink, M.4
Madiredjo, M.5
Bernards, R.6
Berkhout, B.7
-
30
-
-
9144270207
-
Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides
-
Egelhofer, M.; Brandenburg, G.; Martinius, H.; Schult-Dietrich, P.; Melikyan, G.; Kunert, R.; Baum, C.; Choi, I.; Alexandrov, A.; von Laer, D. Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides. J. Virol. 2004, 78, 568-575.
-
(2004)
J. Virol
, vol.78
, pp. 568-575
-
-
Egelhofer, M.1
Brandenburg, G.2
Martinius, H.3
Schult-Dietrich, P.4
Melikyan, G.5
Kunert, R.6
Baum, C.7
Choi, I.8
Alexandrov, A.9
von Laer, D.10
-
31
-
-
34247208235
-
Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus
-
Van Lunzen, J.; Glaunsinger, T.; Stahmer, I.; von Baehr, V.; Baum, C.; Schilz, A.; Kuehlcke, K.; Naundorf, S.; Martinius, H.; Hermann, F. et al. Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus. Mol. Ther. 2007, 15, 1024-1033.
-
(2007)
Mol. Ther
, vol.15
, pp. 1024-1033
-
-
van Lunzen, J.1
Glaunsinger, T.2
Stahmer, I.3
von Baehr, V.4
Baum, C.5
Schilz, A.6
Kuehlcke, K.7
Naundorf, S.8
Martinius, H.9
Hermann, F.10
-
32
-
-
1542288934
-
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys
-
Stremlau, M.; Owens, C.M.; Perron, M.J.; Kiessling, M.; Autissier, P.; Sodroski, J. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 2004, 427, 848-853.
-
(2004)
Nature
, vol.427
, pp. 848-853
-
-
Stremlau, M.1
Owens, C.M.2
Perron, M.J.3
Kiessling, M.4
Autissier, P.5
Sodroski, J.6
-
33
-
-
33745800238
-
Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection
-
Li, Y.; Li, X.; Stremlau, M.; Lee, M.; Sodroski, J. Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection. J. Virol. 2006, 80, 6738-6744.
-
(2006)
J. Virol
, vol.80
, pp. 6738-6744
-
-
Li, Y.1
Li, X.2
Stremlau, M.3
Lee, M.4
Sodroski, J.5
-
34
-
-
41149134501
-
Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34(+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with human fetal tissue
-
Anderson, J.; Akkina, R. Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34(+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with human fetal tissue. Human Gene Ther. 2008, 19, 217-228.
-
(2008)
Human Gene Ther
, vol.19
, pp. 217-228
-
-
Anderson, J.1
Akkina, R.2
-
35
-
-
70349655695
-
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
-
Neagu, M.R.; Ziegler, P.; Pertel, T.; Strambio-De-Castillia, C.; Grütter, C.; Martinetti, G.; Mazzucchelli, L.; Grütter, M.; Manz, M.G.; Luban, J. Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J. Clin. Invest. 2009, 119, 3035-3047.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 3035-3047
-
-
Neagu, M.R.1
Ziegler, P.2
Pertel, T.3
Strambio-De-Castillia, C.4
Grütter, C.5
Martinetti, G.6
Mazzucchelli, L.7
Grütter, M.8
Manz, M.G.9
Luban, J.10
-
36
-
-
18744408157
-
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes
-
Li, X.; Afif, H.; Cheng, S.; Martel-Pelletier, J.; Pelletier, J.-P.; Ranger, P.; Fahmi, H. Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. J. Rheumatol. 2005, 32, 887-895.
-
(2005)
J. Rheumatol
, vol.32
, pp. 887-895
-
-
Li, X.1
Afif, H.2
Cheng, S.3
Martel-Pelletier, J.4
Pelletier, J.-P.5
Ranger, P.6
Fahmi, H.7
-
37
-
-
1642380210
-
A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif)
-
Schröfelbauer, B.; Chen, D.; Landau, N.R. A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif). Proc. Natl. Acad. Sci. USA 2004, 101, 3927-3932.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3927-3932
-
-
Schröfelbauer, B.1
Chen, D.2
Landau, N.R.3
-
38
-
-
61449243774
-
Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants
-
McNatt, M.W.; Zang, T.; Hatziioannou, T.; Bartlett, M.; Ben Fofana, I.; Johnson, W.E.; Neil, S.J.D.; Bieniasz, P.D.; Hope, T.J. Species-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variants. PLoS Pathog. 2009, 5, e1000300.
-
(2009)
PLoS Pathog
, vol.5
-
-
McNatt, M.W.1
Zang, T.2
Hatziioannou, T.3
Bartlett, M.4
Ben Fofana, I.5
Johnson, W.E.6
Neil, S.J.D.7
Bieniasz, P.D.8
Hope, T.J.9
-
39
-
-
77955608799
-
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma
-
DiGiusto, D.L.; Krishnan, A.; Li, L.; Li, H.; Li, S.; Rao, A.; Mi, S.; Yam, P.; Stinson, S.; Kalos, M. et al. RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Sci. Transl. Med. 2010, 2, 36ra43.
-
(2010)
Sci. Transl. Med
, vol.2
-
-
Digiusto, D.L.1
Krishnan, A.2
Li, L.3
Li, H.4
Li, S.5
Rao, A.6
Mi, S.7
Yam, P.8
Stinson, S.9
Kalos, M.10
-
40
-
-
74349091890
-
Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo
-
Kiem, H.-P.; Wu, R.A.; Sun, G.; von Laer, D.; Rossi, J.J.; Trobridge, G.D. Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo. Gene Ther. 2010, 17, 37-49.
-
(2010)
Gene Ther
, vol.17
, pp. 37-49
-
-
Kiem, H.-P.1
Wu, R.A.2
Sun, G.3
von Laer, D.4
Rossi, J.J.5
Trobridge, G.D.6
-
41
-
-
33751001588
-
Silencing of HIV-1 with RNA interference: A multiple shRNA approach
-
ter Brake, O.; Konstantinova, P.; Ceylan, M.; Berkhout, B. Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol. Ther. 2006, 14, 883-892.
-
(2006)
Mol. Ther
, vol.14
, pp. 883-892
-
-
ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
42
-
-
84867743427
-
Endogenous MCM7 MicroRNA cluster as a novel platform to multiplex small interfering and nucleolar RNAs for combinational HIV-1 gene therapy
-
Chung, J.; Zhang, J.; Li, H.; Ouellet, D.L.; DiGiusto, D.L.; Rossi, J.J. Endogenous MCM7 MicroRNA cluster as a novel platform to multiplex small interfering and nucleolar RNAs for combinational HIV-1 gene therapy. Human Gene Ther. 2012, 23, 1200-1208.
-
(2012)
Human Gene Ther
, vol.23
, pp. 1200-1208
-
-
Chung, J.1
Zhang, J.2
Li, H.3
Ouellet, D.L.4
Digiusto, D.L.5
Rossi, J.J.6
-
43
-
-
84875012329
-
Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells
-
Choudhary, R.; Baturin, D.; Fosmire, S.; Freed, B.; Porter, C.C. Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells. PLoS One 2013, 8, e59594.
-
(2013)
PLoS One
, vol.8
-
-
Choudhary, R.1
Baturin, D.2
Fosmire, S.3
Freed, B.4
Porter, C.C.5
-
44
-
-
84891480145
-
Genetic modification of mouse bone marrow by lentiviral vector-mediated delivery of hypoxanthine-Guanine phosphoribosyltransferase short hairpin RNA confers chemoprotection against 6-thioguanine cytotoxicity
-
Hacke, K.; Treger, J.A.; Bogan, B.T.; Schiestl, R.H.; Kasahara, N. Genetic modification of mouse bone marrow by lentiviral vector-mediated delivery of hypoxanthine-Guanine phosphoribosyltransferase short hairpin RNA confers chemoprotection against 6-thioguanine cytotoxicity. Transplant. Proc. 2013, 45, 2040-2044.
-
(2013)
Transplant. Proc
, vol.45
, pp. 2040-2044
-
-
Hacke, K.1
Treger, J.A.2
Bogan, B.T.3
Schiestl, R.H.4
Kasahara, N.5
-
45
-
-
77954633050
-
HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals
-
Trono, D.; van Lint, C.; Rouzioux, C.; Verdin, E.; Barré-Sinoussi, F.; Chun, T.-W.; Chomont, N. HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals. Science 2010, 329, 174-180.
-
(2010)
Science
, vol.329
, pp. 174-180
-
-
Trono, D.1
van Lint, C.2
Rouzioux, C.3
Verdin, E.4
Barré-Sinoussi, F.5
Chun, T.-W.6
Chomont, N.7
-
46
-
-
84863337769
-
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
-
Shan, L.; Deng, K.; Shroff, N.S.; Durand, C.M.; Rabi, S.A.; Yang, H.-C.; Zhang, H.; Margolick, J.B.; Blankson, J.N.; Siliciano, R.F. Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 2012, 36, 491-501.
-
(2012)
Immunity
, vol.36
, pp. 491-501
-
-
Shan, L.1
Deng, K.2
Shroff, N.S.3
Durand, C.M.4
Rabi, S.A.5
Yang, H.-C.6
Zhang, H.7
Margolick, J.B.8
Blankson, J.N.9
Siliciano, R.F.10
-
47
-
-
84858790935
-
Small molecules and big killers: The challenge of eliminating the latent HIV reservoir
-
Migueles, S.A.; Connors, M. Small molecules and big killers: The challenge of eliminating the latent HIV reservoir. Immunity 2012, 36, 320-321.
-
(2012)
Immunity
, vol.36
, pp. 320-321
-
-
Migueles, S.A.1
Connors, M.2
-
48
-
-
84863705453
-
Therapeutic vaccines against HIV infection
-
Garcia, F.; León, A.; Gatell, J.; Plana, M.; Gallart, T. Therapeutic vaccines against HIV infection. Hum. Vaccines 2012, 8, 569-581.
-
(2012)
Hum. Vaccines
, vol.8
, pp. 569-581
-
-
Garcia, F.1
León, A.2
Gatell, J.3
Plana, M.4
Gallart, T.5
-
49
-
-
78650311033
-
Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine
-
Papagno, L.; Alter, G.; Assoumou, L.; Murphy, R.L.; Garcia, F.; Clotet, B.; Larsen, M.; Braibant, M.; Marcelin, A.-G.; Costagliola, D. et al. Comprehensive analysis of virus-specific T-cells provides clues for the failure of therapeutic immunization with ALVAC-HIV vaccine. AIDS 2011, 25, 27-36.
-
(2011)
AIDS
, vol.25
, pp. 27-36
-
-
Papagno, L.1
Alter, G.2
Assoumou, L.3
Murphy, R.L.4
Garcia, F.5
Clotet, B.6
Larsen, M.7
Braibant, M.8
Marcelin, A.-G.9
Costagliola, D.10
-
50
-
-
23244463710
-
Impact of therapeutic immunization on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection
-
Kinloch-de Loes, S.; Hoen, B.; Smith, D.E.; Autran, B.; Lampe, F.C.; Phillips, A.N.; Goh, L.-E.; Andersson, J.; Tsoukas, C.; Sonnerborg, A. et al. Impact of therapeutic immunization on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection. J. Infect. Dis. 2005, 192, 607-617.
-
(2005)
J. Infect. Dis
, vol.192
, pp. 607-617
-
-
Kinloch-De loes, S.1
Hoen, B.2
Smith, D.E.3
Autran, B.4
Lampe, F.C.5
Phillips, A.N.6
Goh, L.-E.7
Andersson, J.8
Tsoukas, C.9
Sonnerborg, A.10
-
51
-
-
33846574833
-
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes
-
Bozzacco, L.; Trumpfheller, C.; Siegal, F.P.; Mehandru, S.; Markowitz, M.; Carrington, M.; Nussenzweig, M.C.; Piperno, A.G.; Steinman, R.M. DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes. Proc. Natl. Acad. Sci. USA 2007, 104, 1289-1294.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1289-1294
-
-
Bozzacco, L.1
Trumpfheller, C.2
Siegal, F.P.3
Mehandru, S.4
Markowitz, M.5
Carrington, M.6
Nussenzweig, M.C.7
Piperno, A.G.8
Steinman, R.M.9
-
52
-
-
84872037286
-
A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication
-
García, F.; Climent, N.; Guardo, A.C.; Gil, C.; León, A.; Autran, B.; Lifson, J.D.; Martínez-Picado, J.; Dalmau, J.; Clotet, B. et al. A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication. Sci. Transl. Med. 2013, 5, 166ra2.
-
(2013)
Sci. Transl. Med
, vol.5
-
-
García, F.1
Climent, N.2
Guardo, A.C.3
Gil, C.4
León, A.5
Autran, B.6
Lifson, J.D.7
Martínez-Picado, J.8
Dalmau, J.9
Clotet, B.10
-
53
-
-
77953311689
-
Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody
-
Joseph, A.; Zheng, J.H.; Chen, K.; Dutta, M.; Chen, C. Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody. J. Virol. 2010, 84, 6645-6653.
-
(2010)
J. Virol
, vol.84
, pp. 6645-6653
-
-
Joseph, A.1
Zheng, J.H.2
Chen, K.3
Dutta, M.4
Chen, C.5
-
54
-
-
0033887418
-
Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes
-
Cooper, L.J.; Kalos, M.; Lewinsohn, D.A.; Riddell, S.R.; Greenberg, P.D. Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes. J. Virol. 2000, 74, 8207-8212.
-
(2000)
J. Virol
, vol.74
, pp. 8207-8212
-
-
Cooper, L.J.1
Kalos, M.2
Lewinsohn, D.A.3
Riddell, S.R.4
Greenberg, P.D.5
-
55
-
-
57349118383
-
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor
-
Varela-Rohena, A.; Molloy, P.E.; Dunn, S.M.; Li, Y.; Suhoski, M.M.; Carroll, R.G.; Milicic, A.; Mahon, T.; Sutton, D.H.; Laugel, B. et al. Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor. Nat. Med. 2008, 14, 1390-1395.
-
(2008)
Nat. Med
, vol.14
, pp. 1390-1395
-
-
Varela-Rohena, A.1
Molloy, P.E.2
Dunn, S.M.3
Li, Y.4
Suhoski, M.M.5
Carroll, R.G.6
Milicic, A.7
Mahon, T.8
Sutton, D.H.9
Laugel, B.10
-
56
-
-
84891469461
-
-
Redirected High Affinity Ga-Specific Autologous T Cells for HIV Gene Therapy. Available online, accessed on 19 December 2013
-
Redirected High Affinity Ga-Specific Autologous T Cells for HIV Gene Therapy. Available online: http://clinicaltrials.gov/show/NCT00991224 (accessed on 19 December 2013).
-
-
-
-
57
-
-
84860718270
-
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells
-
Scholler, J.; Brady, T.L.; Binder-Scholl, G.; Hwang, W.-T.; Plesa, G.; Hege, K.M.; Vogel, A.N.; Kalos, M.; Riley, J.L.; Deeks, S.G. et al. Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells. Sci. Transl. Med. 2012, 4, 132ra53.
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Scholler, J.1
Brady, T.L.2
Binder-Scholl, G.3
Hwang, W.-T.4
Plesa, G.5
Hege, K.M.6
Vogel, A.N.7
Kalos, M.8
Riley, J.L.9
Deeks, S.G.10
-
58
-
-
0034254611
-
Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects
-
Mitsuyasu, R.T.; Anton, P.A.; Deeks, S.G.; Scadden, D.T.; Connick, E.; Downs, M.T.; Bakker, A.; Roberts, M.R.; June, C.H.; Jalali, S. et al. Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects. Blood 2000, 96, 785-793.
-
(2000)
Blood
, vol.96
, pp. 785-793
-
-
Mitsuyasu, R.T.1
Anton, P.A.2
Deeks, S.G.3
Scadden, D.T.4
Connick, E.5
Downs, M.T.6
Bakker, A.7
Roberts, M.R.8
June, C.H.9
Jalali, S.10
-
59
-
-
84877030619
-
Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression
-
Vatakis, D.N.; Arumugam, B.; Kim, S.G.; Bristol, G.; Yang, O.; Zack, J.A. Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression. Mol. Ther. 2013, 21, 1055-1063.
-
(2013)
Mol. Ther
, vol.21
, pp. 1055-1063
-
-
Vatakis, D.N.1
Arumugam, B.2
Kim, S.G.3
Bristol, G.4
Yang, O.5
Zack, J.A.6
-
60
-
-
84861206611
-
In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells
-
Kitchen, S.G.; Levin, B.R.; Bristol, G.; Rezek, V.; Kim, S.; Aguilera-Sandoval, C.; Balamurugan, A.; Yang, O.O.; Zack, J.A. In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells. PLoS Pathog. 2012, 8, e1002649.
-
(2012)
PLoS Pathog
, vol.8
-
-
Kitchen, S.G.1
Levin, B.R.2
Bristol, G.3
Rezek, V.4
Kim, S.5
Aguilera-Sandoval, C.6
Balamurugan, A.7
Yang, O.O.8
Zack, J.A.9
-
61
-
-
78650664088
-
Rapid T cell receptor delineation reveals clonal expansion limitation of the magnitude of the HIV-1-specific CD8+ T cell response
-
Balamurugan, A.; Ng, H.L.; Yang, O.O. Rapid T cell receptor delineation reveals clonal expansion limitation of the magnitude of the HIV-1-specific CD8+ T cell response. J. Immunol. 2010, 185, 5935-5942.
-
(2010)
J. Immunol
, vol.185
, pp. 5935-5942
-
-
Balamurugan, A.1
Ng, H.L.2
Yang, O.O.3
-
62
-
-
59449098985
-
Gene therapy for immunodeficiency due to adenosine deaminase deficiency
-
Aiuti, A.; Cattaneo, F.; Galimberti, S.; Benninghoff, U.; Cassani, B.; Callegaro, L.; Scaramuzza, S.; Andolfi, G.; Mirolo, M.; Brigida, I. et al. Gene therapy for immunodeficiency due to adenosine deaminase deficiency. N. Engl. J. Med. 2009, 360, 447-458.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 447-458
-
-
Aiuti, A.1
Cattaneo, F.2
Galimberti, S.3
Benninghoff, U.4
Cassani, B.5
Callegaro, L.6
Scaramuzza, S.7
Andolfi, G.8
Mirolo, M.9
Brigida, I.10
|