Aging promotes b-1b cell responses to native, but not protein-conjugated, pneumococcal polysaccharides: Implications for vaccine protection in older adults

Journal of Infectious Diseases

Volumn 209, Issue 1, 2014, Pages 87-97

  Haas, Karen M ^a   Blevins, Maria W ^a   High, Kevin P ^a   Pang, Bing ^a   Swords, W Edward ^a   Yammani, Rama D ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

aging; B 1b cells; humoral immunity; Pneumovax23; Prevnar 13; Streptococcus pneumoniae; vaccines

Indexed keywords

IMMUNOGLOBULIN G; PNEUMOCOCCUS VACCINE;

ADULT; AGED; AGING; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; BACTEREMIA; BONE MARROW CELL; CELL EXPANSION; CONTROLLED STUDY; GENE REARRANGEMENT; GROUPS BY AGE; HUMORAL IMMUNITY; IMMUNIZATION; INFECTION SENSITIVITY; MALE; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SEROTYPE; SPLEEN CELL; SURVIVAL RATE; YOUNG ADULT;

AGING; B-1B CELLS; HUMORAL IMMUNITY; PNEUMOVAX23; PREVNAR-13; STREPTOCOCCUS PNEUMONIAE; VACCINES;

AGE FACTORS; ANIMALS; ANTIBODIES, BACTERIAL; B-LYMPHOCYTE SUBSETS; DISEASE SUSCEPTIBILITY; IMMUNITY, HUMORAL; MALE; MICE; MICE, INBRED C57BL; PNEUMOCOCCAL VACCINES; PNEUMONIA, PNEUMOCOCCAL; POLYSACCHARIDES, BACTERIAL;

EID: 84891365797     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit442     Document Type: Article

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