Genome-wide association study identifies a potent locus associated with human opioid sensitivity

Molecular Psychiatry

Volumn 19, Issue 1, 2014, Pages 55-62

  Nishizawa, D ^a   Fukuda, K ^b   Kasai, S ^a   Hasegawa, J ^a   Aoki, Y ^a,b   Nishi, A ^a   Saita, N ^b   Koukita, Y ^b   Nagashima, M ^c   Katoh, R ^c   Satoh, Y ^c   Tagami, M ^c   Higuchi, S ^d   Ujike, H ^e,f   Ozaki, N ^c   Inada, T ^g   Iwata, N ^h   Sora, I ^a,i   Iyo, M ^j   Kondo, N ^k   Won, M J ^l   Naruse, N ^m   Uehara Aoyama, K ⁿ   Itokawa, M ^a   Koga, M ^o   Arinami, T ^o   Kaneko, Y ^b   Hayashida, M ^p   Ikeda, K ^a   more..

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b Department of Oral Health and Clinical Science   (Japan)

^c TOHO UNIVERSITY SAKURA MEDICAL CENTER   (Japan)

^d KURIHAMA NATIONAL HOSPITAL   (Japan)

^e Ujike Nishiguchi Clinic   (Japan)

^f NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g SEIWA HOSPITAL   (Japan)

^h FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^j CHIBA UNIVERSITY   (Japan)

^k Seimei Hospital   (Japan)

^l Koujin Hospital   (Japan)

^m Saitama Seishin iryo Center   (Japan)

ⁿ Kanagawa Kenritsu Seisin Iryo Senta Serigaya Byoin   (Japan)

^o UNIVERSITY OF TSUKUBA   (Japan)

^p JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

more..

Author keywords

analgesia; dependence; opioids; pharmacogenetics

Indexed keywords

FENTANYL; MESSENGER RNA; OPIATE;

ABDOMINAL SURGERY; ALCOHOLISM; ALLELE; ARTICLE; CREB1 GENE; DISEASE SEVERITY; DRUG DEPENDENCE; EATING DISORDER; ESTHETIC SURGERY; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; METHAMPHETAMINE DEPENDENCE; METTL21A GENE; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; CHROMOSOMES, HUMAN, PAIR 2; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA MODIFICATION METHYLASES; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHIATRIC STATUS RATING SCALES; RECONSTRUCTIVE SURGICAL PROCEDURES; SUBSTANCE-RELATED DISORDERS; YOUNG ADULT;

EID: 84891166214     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2012.164     Document Type: Article

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