The role of NOD2 in murine and human melioidosis

Journal of Immunology

Volumn 192, Issue 1, 2014, Pages 300-307

  Myers, Nicolle D ^a   Chantratita, Narisara ^b   Berrington, William R ^a   Chierakul, Wirongrong ^b   Limmathurotsakul, Direk ^b   Wuthiekanun, Vanaporn ^b   Robertson, Johanna D ^a   Liggitt, H Denny ^a   Peacock, Sharon J ^b,c   Skerrett, Shawn J ^a   West, T Eoin ^a,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CXCL1 CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERIAL REPRODUCTION; BURKHOLDERIA PSEUDOMALLEI; CELL STIMULATION; CELL STRAIN HEK293; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETIC VARIABILITY; HISTOPATHOLOGY; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; MELIOIDOSIS; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN FUNCTION; SEX DIFFERENCE; WILD TYPE;

EID: 84891122272     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1301436     Document Type: Article

References (47)

1. Wiersinga, W. J., B. J. Currie, and S. J. Peacock. 2012. Melioidosis. N. Engl. J. Med. 367: 1035-1044.
2. West, T. E., R. K. Ernst, M. J. Jansson-Hutson, and S. J. Skerrett. 2008. Activation of Toll-like receptors by Burkholderia pseudomallei. BMC Immunol. 9: 46.
3. West, T. E., W. Chierakul, N. Chantratita, D. Limmathurotsakul, V. Wuthiekanun, M. J. Emond, T. R. Hawn, S. J. Peacock, and S. J. Skerrett. 2012. Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis. Genes Immun. 13: 38-46.
4. Wiersinga, W. J., C. W. Wieland, M. C. Dessing, N. Chantratita, A. C. Cheng, D. Limmathurotsakul, W. Chierakul, M. Leendertse, S. Florquin, A. F. de Vos, et al. 2007. Toll-like receptor 2 impairs host defense in Gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis). PLoS Med. 4: e248.
5. West, T. E., N. Chantratita, W. Chierakul, D. Limmathurotsakul, V. Wuthiekanun, N. D. Myers, M. J. Emond, M. M. Wurfel, T. R. Hawn, S. J. Peacock, and S. J. Skerrett. 2013. Impaired TLR5 functionality is associated with survival in melioidosis. J. Immunol. 190: 3373-3379.
6. West, T. E., T. R. Hawn, and S. J. Skerrett. 2009. Toll-like receptor signaling in airborne Burkholderia thailandensis infection. Infect. Immun. 77: 5612-5622.
7. Franchi, L., J. H. Park, M. H. Shaw, N. Marina-Garcia, G. Chen, Y. G. Kim, and G. Núñez. 2008. Intracellular NOD-like receptors in innate immunity, infection and disease. Cell. Microbiol. 10: 1-8.
8. Shaw, M. H., T. Reimer, Y. G. Kim, and G. Nuñez. 2008. NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Curr. Opin. Immunol. 20: 377-382.
9. Inohara, N., M. Chamaillard, C. McDonald, and G. Nuñez. 2005. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 74: 355-383.
10. Kawai, T., and S. Akira. 2009. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int. Immunol. 21: 317-337.
11. Bourhis, L. L., and C. Werts. 2007. Role of Nods in bacterial infection. Microbes Infect. 9: 629-636.
12. Harley, V. S., D. A. Dance, G. Tovey, M. V. McCrossan, and B. S. Drasar. 1998. An ultrastructural study of the phagocytosis of Burkholderia pseudomallei. Microbios 94: 35-45.
13. Miao, E. A., D. P. Mao, N. Yudkovsky, R. Bonneau, C. G. Lorang, S. E. Warren, I. A. Leaf, and A. Aderem. 2010. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc. Natl. Acad. Sci. USA 107: 3076-3080.
14. Breitbach, K., G. W. Sun, J. Köhler, K. Eske, P. Wongprompitak, G. Tan, Y. Liu, Y. H. Gan, and I. Steinmetz. 2009. Caspase-1 mediates resistance in murine melioidosis. Infect. Immun. 77: 1589-1595.
15. Ceballos-Olvera, I., M. Sahoo, M. A. Miller, L. Del Barrio, and F. Re. 2011. Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1b is deleterious. PLoS Pathog. 7: e1002452.
16. Pudla, M., A. Kananurak, K. Limposuwan, S. Sirisinha, and P. Utaisincharoen. 2011. Nucleotide-binding oligomerization domain-containing protein 2 regulates suppressor of cytokine signaling 3 expression in Burkholderia pseudomalleiinfected mouse macrophage cell line RAW 264.7. Innate Immun. 17: 532-540.
17. West, T. E., N. D. Myers, D. Limmathurotsakul, H. D. Liggitt, N. Chantratita, S. J. Peacock, and S. J. Skerrett. 2010. Pathogenicity of high-dose enteral inoculation of Burkholderia pseudomallei to mice. Am. J. Trop. Med. Hyg. 83: 1066-1069.
18. West, T. E., N. D. Myers, H. D. Liggitt, and S. J. Skerrett. 2012. Murine pulmonary infection and inflammation induced by inhalation of Burkholderia pseudomallei. Int. J. Exp. Pathol. 93: 421-428.
19. Berrington, W. R., R. Iyer, R. D. Wells, K. D. Smith, S. J. Skerrett, and T. R. Hawn. 2010. NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila. Eur. J. Immunol. 40: 3519-3527.
20. Vannberg, F. O., S. J. Chapman, and A. V. Hill. 2011. Human genetic susceptibility to intracellular pathogens. Immunol. Rev. 240: 105-116.
21. Abraham, C., and J. H. Cho. 2006. Functional consequences of NOD2 (CARD15) mutations. Inflamm. Bowel Dis. 12: 641-650.
22. Zhang, F. R., W. Huang, S. M. Chen, L. D. Sun, H. Liu, Y. Li, Y. Cui, X. X. Yan, H. T. Yang, R. D. Yang, et al. 2009. Genomewide association study of leprosy. N. Engl. J. Med. 361: 2609-2618.
23. Berrington, W. R., M. Macdonald, S. Khadge, B. R. Sapkota, M. Janer, D. A. Hagge, G. Kaplan, and T. R. Hawn. 2010. Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states. J. Infect. Dis. 201: 1422-1435.
24. Grant, A. V., A. Alter, N. T. Huong, M. Orlova, N. Van Thuc, N. N. Ba, V. H. Thai, L. Abel, E. Schurr, and A. Alcais. 2012. Crohn's disease susceptibility genes are associated with leprosy in the Vietnamese population. J. Infect. Dis. 206: 1763-1767.
25. Theivanthiran, B., S. Batra, G. Balamayooran, S. Cai, K. Kobayashi, R. A. Flavell, and S. Jeyaseelan. 2012. NOD2 signaling contributes to host defense in the lungs against Escherichia coli infection. Infect. Immun. 80: 2558-2569.
26. Shimada, K., S. Chen, P. W. Dempsey, R. Sorrentino, R. Alsabeh, A. V. Slepenkin, E. Peterson, T. M. Doherty, D. Underhill, T. R. Crother, and M. Arditi. 2009. The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection. PLoS Pathog. 5: e1000379.
27. Opitz, B., A. Püschel, B. Schmeck, A. C. Hocke, S. Rosseau, S. Hammerschmidt, R. R. Schumann, N. Suttorp, and S. Hippenstiel. 2004. Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. J. Biol. Chem. 279: 36426-36432.
28. Kapetanovic, R., M. A. Nahori, V. Balloy, C. Fitting, D. J. Philpott, J. M. Cavaillon, and M. Adib-Conquy. 2007. Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophages. Infect. Immun. 75: 830-837.
29. Kobayashi, K. S., M. Chamaillard, Y. Ogura, O. Henegariu, N. Inohara, G. Nuñez, and R. A. Flavell. 2005. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307: 731-734.
30. Frutuoso, M. S., J. I. Hori, M. S. Pereira, D. S. Junior, F. Sonego, K. S. Kobayashi, R. A. Flavell, F. Q. Cunha, and D. S. Zamboni. 2010. The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila. Microbes Infect. 12: 819-827.
31. Travassos, L. H., L. A. Carneiro, M. Ramjeet, S. Hussey, Y. G. Kim, J. G. Magalhães, L. Yuan, F. Soares, E. Chea, L. Le Bourhis, et al. 2010. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat. Immunol. 11: 55-62.
32. Cullinane, M., L. Gong, X. Li, N. Lazar-Adler, T. Tra, E. Wolvetang, M. Prescott, J. D. Boyce, R. J. Devenish, and B. Adler. 2008. Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines. Autophagy 4: 744-753.
33. Miceli-Richard, C., S. Lesage, M. Rybojad, A. M. Prieur, S. Manouvrier-Hanu, R. Häfner, M. Chamaillard, H. Zouali, G. Thomas, and J. P. Hugot. 2001. CARD15 mutations in Blau syndrome. Nat. Genet. 29: 19-20.
34. Kanazawa, N., I. Okafuji, N. Kambe, R. Nishikomori, M. Nakata-Hizume, S. Nagai, A. Fuji, T. Yuasa, A. Manki, Y. Sakurai, et al. 2005. Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome. Blood 105: 1195-1197.
35. Weidinger, S., N. Klopp, L. Rummler, S. Wagenpfeil, H. J. Baurecht, A. Gauger, U. Darsow, T. Jakob, N. Novak, T. Schafer, et al. 2005. Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults. Clin. Exp. Allergy 35: 866-872.
36. Kinose, D., E. Ogawa, T. Hirota, I. Ito, M. Kudo, A. Haruna, S. Marumo, Y. Hoshino, S. Muro, T. Hirai, et al. 2012. A NOD2 gene polymorphism is associated with the prevalence and severity of chronic obstructive pulmonary disease in a Japanese population. Respirology 17: 164-171.
37. Pan, H., Y. Dai, S. Tang, and J. Wang. 2012. Polymorphisms of NOD2 and the risk of tuberculosis: a validation study in the Chinese population. Int. J. Immunogenet. 39: 233-240.
38. Koh, G. C., M. F. Schreiber, R. Bautista, R. R. Maude, S. Dunachie, D. Limmathurotsakul, N. P. Day, G. Dougan, and S. J. Peacock. 2013. Host responses to melioidosis and tuberculosis are both dominated by interferonmediated signaling. PLoS One 8: e54961.
39. Abecasis, G. R., A. Auton, L. D. Brooks, M. A. DePristo, R. M. Durbin, R. E. Handsaker, H. M. Kang, G. T. Marth, and G. A. McVean; 1000 Genomes Project Consortium. 2012. An integrated map of genetic variation from 1,092 human genomes. Nature 491: 56-65.
40. Boyle, A. P., E. L. Hong, M. Hariharan, Y. Cheng, M. A. Schaub, M. Kasowski, K. J. Karczewski, J. Park, B. C. Hitz, S. Weng, et al. 2012. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22: 1790-1797.
41. Durlach, A., C. Clavel, A. Girard-Globa, and V. Durlach. 1999. Sex-dependent association of a genetic polymorphism of cholesteryl ester transfer protein with high-density lipoprotein cholesterol and macrovascular pathology in type II diabetic patients. J. Clin. Endocrinol. Metab. 84: 3656-3659.
42. Sentí, M., J. M. Fernández-Fernández, M. Tomás, E. Vázquez, R. Elosua, J. Marrugat, and M. A. Valverde. 2005. Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk. Circ. Res. 97: 1360-1365.
43. Corella, D., M. Guillén, O. Portolés, J. V. Sorlí, V. Alonso, J. Folch, and C. Sáiz. 2001. Gender specific associations of the Trp64Arg mutation in the beta3-adrenergic receptor gene with obesity-related phenotypes in a Mediterranean population: interaction with a common lipoprotein lipase gene variation. J. Intern. Med. 250: 348-360.
44. Ordovas, J. M. 2007. Gender, a significant factor in the cross talk between genes, environment, and health. Gend. Med. 4 (Suppl. B): S111-S122.
45. Lefèvre, N., F. Corazza, J. Duchateau, J. Desir, and G. Casimir. 2012. Sex differences in inflammatory cytokines and CD99 expression following in vitro lipopolysaccharide stimulation. Shock 38: 37-42.
46. Imahara, S. D., S. Jelacic, C. E. Junker, and G. E. O'Keefe. 2005. The influence of gender on human innate immunity. Surgery 138: 275-282.
47. Pennell, L. M., C. L. Galligan, and E. N. Fish. 2012. Sex affects immunity. J. Autoimmun. 38: J282-J291.