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Volumn 258, Issue , 2014, Pages 355-363

Acute exercise-induced activation of Phox2b-expressing neurons of the retrotrapezoid nucleus in rats may involve the hypothalamus

Author keywords

Breathing; C Fos immunoreactivity; Central autonomic pathways; Exercise; Medulla oblongata; Phox2b

Indexed keywords

HOMEODOMAIN PROTEIN; MESSENGER RNA; PAIRED LIKE HOMEOBOX 2B; PROTEIN C FOS; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 2;

EID: 84891113853     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.11.031     Document Type: Article
Times cited : (40)

References (58)
  • 1
    • 67651119955 scopus 로고    scopus 로고
    • Galanin microinjection into the PreBötzinger or the Bötzinger Complex terminates central inspiratory activity and reduces responses to hypoxia and hypercapnia in rat
    • Abbott S.B., Burke P.G., Pilowsky P.M. Galanin microinjection into the PreBötzinger or the Bötzinger Complex terminates central inspiratory activity and reduces responses to hypoxia and hypercapnia in rat. Respir Physiol Neurobiol 2009, 167:299-306.
    • (2009) Respir Physiol Neurobiol , vol.167 , pp. 299-306
    • Abbott, S.B.1    Burke, P.G.2    Pilowsky, P.M.3
  • 2
    • 80755127200 scopus 로고    scopus 로고
    • Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats
    • Abbott S.B., Stornetta R.L., Coates M.B., Guyenet P.G. Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats. J Neurosci 2011, 31:16410-16422.
    • (2011) J Neurosci , vol.31 , pp. 16410-16422
    • Abbott, S.B.1    Stornetta, R.L.2    Coates, M.B.3    Guyenet, P.G.4
  • 3
    • 67651114060 scopus 로고    scopus 로고
    • Abdominal expiratory activity in the rat brainstem-spinal cord in situ: patterns, origins and implications for respiratory rhythm generation
    • Abdala A.P., Rybak I.A., Smith J.C., Paton J.F. Abdominal expiratory activity in the rat brainstem-spinal cord in situ: patterns, origins and implications for respiratory rhythm generation. J Physiol 2009, 587:3539-3559.
    • (2009) J Physiol , vol.587 , pp. 3539-3559
    • Abdala, A.P.1    Rybak, I.A.2    Smith, J.C.3    Paton, J.F.4
  • 4
    • 84861662851 scopus 로고    scopus 로고
    • Pontomedullary and hypothalamic distribution of Fos-like immunoreactive neurons after acute exercise in rats
    • Barna B.F., Takakura A.C., Moreira T.S. Pontomedullary and hypothalamic distribution of Fos-like immunoreactive neurons after acute exercise in rats. Neuroscience 2012, 212:120-130.
    • (2012) Neuroscience , vol.212 , pp. 120-130
    • Barna, B.F.1    Takakura, A.C.2    Moreira, T.S.3
  • 6
    • 0028095459 scopus 로고
    • Spatially and temporally differentiated patterns of c-fos expression in the brainstem catecholaminergic cell groups induced by cardiovascular challenges in the rat
    • Chan R.K.W., Sawchenko P.E. Spatially and temporally differentiated patterns of c-fos expression in the brainstem catecholaminergic cell groups induced by cardiovascular challenges in the rat. J Comp Neurol 1994, 348:433-460.
    • (1994) J Comp Neurol , vol.348 , pp. 433-460
    • Chan, R.K.W.1    Sawchenko, P.E.2
  • 7
    • 0023162214 scopus 로고
    • Studies on arterial chemoreceptors in man
    • Cunningham D.J. Studies on arterial chemoreceptors in man. J Physiol 1987, 384:1-26.
    • (1987) J Physiol , vol.384 , pp. 1-26
    • Cunningham, D.J.1
  • 8
    • 65449121472 scopus 로고    scopus 로고
    • Antagonism of orexin receptor 1 (OX1R) in the retrotrapezoid nucleus (RTN) inhibits the ventilatory response to hypercapnia predominantly in wakefulness
    • Dias M.B., Li A., Nattie E.E. Antagonism of orexin receptor 1 (OX1R) in the retrotrapezoid nucleus (RTN) inhibits the ventilatory response to hypercapnia predominantly in wakefulness. J Physiol 2009, 587:2059-2067.
    • (2009) J Physiol , vol.587 , pp. 2059-2067
    • Dias, M.B.1    Li, A.2    Nattie, E.E.3
  • 9
    • 0036159866 scopus 로고    scopus 로고
    • The dorsomedial hypothalamus and the response to stress: part renaissance, part revolution
    • Dimicco J.A., Samuels B.C., Zaretskaia M.V., Zaretsky D.V. The dorsomedial hypothalamus and the response to stress: part renaissance, part revolution. Pharmacol Biochem Behav 2002, 71:469-480.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 469-480
    • Dimicco, J.A.1    Samuels, B.C.2    Zaretskaia, M.V.3    Zaretsky, D.V.4
  • 10
    • 84891046636 scopus 로고    scopus 로고
    • The fast exercise drive to breathe.
    • Duffin J (2013) The fast exercise drive to breathe. J Physiol, in press.
    • (2013) J Physiol, in press.
    • Duffin, J.1
  • 11
    • 0028271470 scopus 로고
    • Central integration of mechanisms in exercise hyperpnea
    • Eldridge F.L. Central integration of mechanisms in exercise hyperpnea. Med Sci Sports Exerc 1994, 26:319-327.
    • (1994) Med Sci Sports Exerc , vol.26 , pp. 319-327
    • Eldridge, F.L.1
  • 12
    • 0019497998 scopus 로고
    • Exercise hyperpnea and locomotion: parallel activation from the hypothalamus
    • Eldridge F.L., Millhorn D.E., Waldrop T.G. Exercise hyperpnea and locomotion: parallel activation from the hypothalamus. Science 1981, 211:844-846.
    • (1981) Science , vol.211 , pp. 844-846
    • Eldridge, F.L.1    Millhorn, D.E.2    Waldrop, T.G.3
  • 14
    • 70450214121 scopus 로고    scopus 로고
    • Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation
    • Fortuna M.G., Stornetta R.L., West G.H., Guyenet P.G. Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation. J Physiol 2009, 587:5121-5138.
    • (2009) J Physiol , vol.587 , pp. 5121-5138
    • Fortuna, M.G.1    Stornetta, R.L.2    West, G.H.3    Guyenet, P.G.4
  • 15
    • 0021132921 scopus 로고
    • Arterial blood acid-base regulation during exercise in rats
    • Fregosi R.F., Dempsey J.A. Arterial blood acid-base regulation during exercise in rats. J Appl Physiol 1984, 57:396-402.
    • (1984) J Appl Physiol , vol.57 , pp. 396-402
    • Fregosi, R.F.1    Dempsey, J.A.2
  • 16
    • 77949413839 scopus 로고    scopus 로고
    • Pareventricular hypothalamic nucleus: axonal projections to the brainstem
    • Geerling J.C., Shin J.W., Chimenti P.C., Loewy A.D. Pareventricular hypothalamic nucleus: axonal projections to the brainstem. J Comp Neurol 2010, 518:1460-1499.
    • (2010) J Comp Neurol , vol.518 , pp. 1460-1499
    • Geerling, J.C.1    Shin, J.W.2    Chimenti, P.C.3    Loewy, A.D.4
  • 17
    • 0015418946 scopus 로고
    • Cardiovascular and respiratory responses to changes in central command during isometric exercise at constant muscle tension
    • Goodwin G.M., McCloskey D.I., Mitchell J.H. Cardiovascular and respiratory responses to changes in central command during isometric exercise at constant muscle tension. J Physiol 1972, 226:173-190.
    • (1972) J Physiol , vol.226 , pp. 173-190
    • Goodwin, G.M.1    McCloskey, D.I.2    Mitchell, J.H.3
  • 19
    • 33745712914 scopus 로고    scopus 로고
    • The sympathetic control of blood pressure
    • Guyenet P.G. The sympathetic control of blood pressure. Nat Rev Neurosci 2006, 7:335-346.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 335-346
    • Guyenet, P.G.1
  • 22
    • 0022558279 scopus 로고
    • A search for brain stem cell groups integrating the defence reaction in the rat
    • Hilton S.M., Redfern W.S. A search for brain stem cell groups integrating the defence reaction in the rat. J Physiol 1986, 378:213-228.
    • (1986) J Physiol , vol.378 , pp. 213-228
    • Hilton, S.M.1    Redfern, W.S.2
  • 23
    • 0032458669 scopus 로고    scopus 로고
    • Suprapontine control of respiration
    • Horn E.M., Waldrop T.G. Suprapontine control of respiration. Respir Physiol 1998, 114:201-211.
    • (1998) Respir Physiol , vol.114 , pp. 201-211
    • Horn, E.M.1    Waldrop, T.G.2
  • 24
    • 0037199829 scopus 로고    scopus 로고
    • Changes in the exercise activation of diencephalic and brainstem cardiorespiratory areas after training
    • Ichiyama R.M., Gilbert A.B., Waldrop T.G., Iwamoto G.A. Changes in the exercise activation of diencephalic and brainstem cardiorespiratory areas after training. Brain Res 2002, 947:225-233.
    • (2002) Brain Res , vol.947 , pp. 225-233
    • Ichiyama, R.M.1    Gilbert, A.B.2    Waldrop, T.G.3    Iwamoto, G.A.4
  • 25
    • 0030575322 scopus 로고    scopus 로고
    • Identification of diencephalic and brainstem cardiorespiratory areas activated during exercise
    • Iwamoto G.A., Wappel S.M., Fox G.M., Buetow K.A., Waldrop T.G. Identification of diencephalic and brainstem cardiorespiratory areas activated during exercise. Brain Res 1996, 726:109-122.
    • (1996) Brain Res , vol.726 , pp. 109-122
    • Iwamoto, G.A.1    Wappel, S.M.2    Fox, G.M.3    Buetow, K.A.4    Waldrop, T.G.5
  • 26
    • 33644559872 scopus 로고    scopus 로고
    • Distinct rhythm generators for inspiration and expiration in the juvenile rat
    • Janczewski W.A., Feldman J.L. Distinct rhythm generators for inspiration and expiration in the juvenile rat. J Physiol 2006, 570:407-420.
    • (2006) J Physiol , vol.570 , pp. 407-420
    • Janczewski, W.A.1    Feldman, J.L.2
  • 28
    • 77956843436 scopus 로고    scopus 로고
    • Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration
    • Marina N., Abdala A.P., Trapp S., Li A., Nattie E.E., Hewinson J., Smith J.C., Paton J.F., Gourine A.V. Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration. J Neurosci 2010, 30:12466-12473.
    • (2010) J Neurosci , vol.30 , pp. 12466-12473
    • Marina, N.1    Abdala, A.P.2    Trapp, S.3    Li, A.4    Nattie, E.E.5    Hewinson, J.6    Smith, J.C.7    Paton, J.F.8    Gourine, A.V.9
  • 29
    • 0029053701 scopus 로고
    • A review of the control of breathing during exercise
    • Mateika J.H., Duffin J. A review of the control of breathing during exercise. Eur J Appl Physiol 1995, 71:1-27.
    • (1995) Eur J Appl Physiol , vol.71 , pp. 1-27
    • Mateika, J.H.1    Duffin, J.2
  • 30
    • 0010651429 scopus 로고
    • Diencephalic regulation of respiration and arterial pressure during actual and fictive locomotion in cat
    • Millhorn D.E., Eldridge F.L., Waldrop T.G., Kiley J.P. Diencephalic regulation of respiration and arterial pressure during actual and fictive locomotion in cat. Circ Res 1987, 61:53-59.
    • (1987) Circ Res , vol.61 , pp. 53-59
    • Millhorn, D.E.1    Eldridge, F.L.2    Waldrop, T.G.3    Kiley, J.P.4
  • 31
    • 33947508131 scopus 로고    scopus 로고
    • Inhibitory input from slowly adapting lung stretch receptor to retrotrapezoid nucleus chemoreceptors
    • Moreira T.S., Takakura A.C., Colombari E., West G.H., Guyenet P.G. Inhibitory input from slowly adapting lung stretch receptor to retrotrapezoid nucleus chemoreceptors. J Physiol 2007, 580:285-300.
    • (2007) J Physiol , vol.580 , pp. 285-300
    • Moreira, T.S.1    Takakura, A.C.2    Colombari, E.3    West, G.H.4    Guyenet, P.G.5
  • 34
    • 30944440241 scopus 로고    scopus 로고
    • Differential responsiveness of c-Fos expression in the rat medulla oblongata to different treadmill running speeds
    • Ohiwa N., Saito T., Chang H., Nakamura T., Soya H. Differential responsiveness of c-Fos expression in the rat medulla oblongata to different treadmill running speeds. Neurosci Res 2006, 54:124-132.
    • (2006) Neurosci Res , vol.54 , pp. 124-132
    • Ohiwa, N.1    Saito, T.2    Chang, H.3    Nakamura, T.4    Soya, H.5
  • 35
    • 84865020700 scopus 로고    scopus 로고
    • State-dependent modulation of breathing in urethane-anesthetized rats
    • Pagliardini S., Greer J.J., Funk G.D., Dickson C.T. State-dependent modulation of breathing in urethane-anesthetized rats. J Neurosci 2012, 32:11259-11270.
    • (2012) J Neurosci , vol.32 , pp. 11259-11270
    • Pagliardini, S.1    Greer, J.J.2    Funk, G.D.3    Dickson, C.T.4
  • 37
    • 84891084956 scopus 로고    scopus 로고
    • Defining the neuro-circuitry of exercise hyperpnoea.
    • Paterson DJ (2013) Defining the neuro-circuitry of exercise hyperpnoea. J Physiol, in press.
    • (2013) J Physiol, in press.
    • Paterson, D.J.1
  • 38
    • 0030731439 scopus 로고    scopus 로고
    • Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis
    • Pattyn A., Morin X., Cremer H., Goridis C., Brunet J.F. Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development 1997, 124:4065-4075.
    • (1997) Development , vol.124 , pp. 4065-4075
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.F.5
  • 41
    • 33748879744 scopus 로고    scopus 로고
    • Afferent and efferent connections of the rat retrotrapezoid nucleus
    • Rosin D.L., Chang D.A., Guyenet P.G. Afferent and efferent connections of the rat retrotrapezoid nucleus. J Comp Neurol 2006, 499:64-89.
    • (2006) J Comp Neurol , vol.499 , pp. 64-89
    • Rosin, D.L.1    Chang, D.A.2    Guyenet, P.G.3
  • 42
    • 0023891990 scopus 로고
    • Expression of c-fos protein in brain: metabolic mapping at the cellular level
    • Sagar S.M., Sharp F.R., Curran T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 1988, 240:1328-1330.
    • (1988) Science , vol.240 , pp. 1328-1330
    • Sagar, S.M.1    Sharp, F.R.2    Curran, T.3
  • 43
    • 0034668802 scopus 로고    scopus 로고
    • Regulation of sympathetic tone and arterial pressure by rostral ventrolateraç medulla after depletion of C1 cells in rat
    • Schreihofer A.M., Stornetta R.L., Guyenet P.G. Regulation of sympathetic tone and arterial pressure by rostral ventrolateraç medulla after depletion of C1 cells in rat. J Physiol 2000, 1:221-236.
    • (2000) J Physiol , vol.1 , pp. 221-236
    • Schreihofer, A.M.1    Stornetta, R.L.2    Guyenet, P.G.3
  • 44
    • 0023259612 scopus 로고
    • Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats
    • Shekhar A., DiMicco J.A. Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats. Neuropharmacology 1987, 26:407-417.
    • (1987) Neuropharmacology , vol.26 , pp. 407-417
    • Shekhar, A.1    DiMicco, J.A.2
  • 46
    • 34547572212 scopus 로고    scopus 로고
    • Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model
    • Soya H., Mukai A., Deocaris C.C., Ohiwa N., Chang H., Nishijima T., Fujikawa T., Togashi K., Saito T. Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model. Neurosci Res 2007, 58:341-348.
    • (2007) Neurosci Res , vol.58 , pp. 341-348
    • Soya, H.1    Mukai, A.2    Deocaris, C.C.3    Ohiwa, N.4    Chang, H.5    Nishijima, T.6    Fujikawa, T.7    Togashi, K.8    Saito, T.9
  • 48
    • 84875263316 scopus 로고    scopus 로고
    • Arterial chemoreceptor activation reduces the activity of parapyramidal serotonergic neurons in rats
    • Takakura A.C., Moreira T.S. Arterial chemoreceptor activation reduces the activity of parapyramidal serotonergic neurons in rats. Neuroscience 2013, 237:199-207.
    • (2013) Neuroscience , vol.237 , pp. 199-207
    • Takakura, A.C.1    Moreira, T.S.2
  • 49
    • 79551529524 scopus 로고    scopus 로고
    • Ventrolateral medulla mechanisms involved in cardiorespiratory responses to central chemoreceptor activation in rats
    • Takakura A.C., Colombari E., Menani J.V., Moreira T.S. Ventrolateral medulla mechanisms involved in cardiorespiratory responses to central chemoreceptor activation in rats. Am J Physiol Regul Integr Comp Physiol 2011, 300:R501-R510.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.300
    • Takakura, A.C.1    Colombari, E.2    Menani, J.V.3    Moreira, T.S.4
  • 51
  • 52
    • 45249119097 scopus 로고    scopus 로고
    • Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats
    • Takakura A.C., Moreira T.S., Stornetta R.L., West G.H., Gwilt J.M., Guyenet P.G. Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats. J Physiol 2008, 586:2975-2991.
    • (2008) J Physiol , vol.586 , pp. 2975-2991
    • Takakura, A.C.1    Moreira, T.S.2    Stornetta, R.L.3    West, G.H.4    Gwilt, J.M.5    Guyenet, P.G.6
  • 54
    • 80155147930 scopus 로고    scopus 로고
    • An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis
    • Tupone D., Madden C.J., Cano G., Morrison S.F. An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis. J Neurosci 2011, 31:15944-15955.
    • (2011) J Neurosci , vol.31 , pp. 15944-15955
    • Tupone, D.1    Madden, C.J.2    Cano, G.3    Morrison, S.F.4
  • 55
    • 0033152526 scopus 로고    scopus 로고
    • Properties of C1 and other ventrolateral medullary neurones with hypothalamic projections in the rat
    • Verberne A.J., Stornetta R.L., Guyenet P.G. Properties of C1 and other ventrolateral medullary neurones with hypothalamic projections in the rat. J Physiol 1999, 517:477-494.
    • (1999) J Physiol , vol.517 , pp. 477-494
    • Verberne, A.J.1    Stornetta, R.L.2    Guyenet, P.G.3
  • 56
    • 0023875535 scopus 로고
    • Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation
    • Waldrop T.G., Bauer R.M., Iwamoto G.A. Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation. Brain Res 1988, 444:84-94.
    • (1988) Brain Res , vol.444 , pp. 84-94
    • Waldrop, T.G.1    Bauer, R.M.2    Iwamoto, G.A.3
  • 57
    • 33645052461 scopus 로고    scopus 로고
    • New insights into central cardiovascular control during exercise in humans: a central command update
    • Williamson J.W., Fadel P.J., Mitchell J.H. New insights into central cardiovascular control during exercise in humans: a central command update. Exp Physiol 2006, 91:51-58.
    • (2006) Exp Physiol , vol.91 , pp. 51-58
    • Williamson, J.W.1    Fadel, P.J.2    Mitchell, J.H.3
  • 58
    • 33744801936 scopus 로고    scopus 로고
    • Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice
    • Zhang W., Sakurai T., Fukuda Y., Kuwaki T. Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice. Am J Physiol Regul Integr Comp Physiol 2006, 290:R1654-R1663.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Zhang, W.1    Sakurai, T.2    Fukuda, Y.3    Kuwaki, T.4


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