Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors

Stem Cells

Volumn 32, Issue 3, 2014, Pages 649-661

  Tang, Jonathan ^a   Fernandez Garcia, Ignacio ^b   Vijayakumar, Sangeetha ^b   Martinez Ruis, Haydeliz ^b   Illa Bochaca, Irineu ^b   Nguyen, David H ^b   Mao, Jian Hua ^a   Costes, Sylvain V ^a   Barcellos Hoff, Mary Helen ^b  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Breast cancer; Epithelial mesenchymal transition; In silico modeling; Ionizing radiation; Mammary stem cell; Multiscale; Notch; Transforming growth factor

Indexed keywords

BREAST CANCER; EPITHELIAL-MESENCHYMAL TRANSITION; IN SILICO MODELING; IONIZING RADIATION; MAMMARY STEM CELL; MULTISCALE; NOTCH; TRANSFORMING GROWTH FACTOR Β;

AGING; ANIMALS; BIOLOGICAL MARKERS; CELL LINE; CELL LINEAGE; CELL PROLIFERATION; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; EPITHELIAL CELLS; FEMALE; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, ANIMAL; MICE; MORPHOGENESIS; RADIATION, IONIZING; RECEPTORS, ESTROGEN; RECEPTORS, NOTCH; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84891105556     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1533     Document Type: Article

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